iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088850

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03081550

Gene Name

WDR59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000003864.2	ENSOGAT00000003868.2	ENSOGAP00000003437.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.30e-19	67.0	190	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d  ++l+++s D+++k WD+r+ 
   Q: 190  HLSKIHGLDWhPDseHILATSSQDNSVKFWDYRQP 224
           99*********6665778*************9876 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAARWSSENV VVEFRDSQAT AMSVDCLGQH AVLSGRRFLY IVNLDAPFEG HRKISRQSKW 60
DIGAVQWNPH DSFAHYFAAS SNQRVDLYKW KDGSGEVGTT LQGHTRVISD LDWAVFEPDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCAC GATGGAGCAG CGAGAACGTG GTGGTGGAGT TTCGGGACTC CCAGGTAGGC 60
TTGAGGGGCT GAAAGGAGCC GTCTGGGCAT GCGCCCTCCC CTCTTCCCTT CCCCGCGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	97.13	0.00e+00	1920.00
IUUC-Apl-004021	Anas platyrhynchos	88.84	0.00e+00	1687.00
IUUC-Aca-004977	Anolis carolinensis	85.01	0.00e+00	1710.00
IUUC-Ago-007961	Ashbya gossypii	29.83	2.00e-57	218.00
IUUC-Acl-008161	Aspergillus clavatus	28.60	2.00e-55	211.00
IUUC-Afl-008686	Aspergillus flavus	28.07	9.00e-58	219.00
IUUC-Afu-008932	Aspergillus fumigatus	34.57	5.00e-52	200.00
IUUC-Ani-009493	Aspergillus nidulans	28.00	4.00e-59	224.00
IUUC-Ang-009876	Aspergillus niger	28.76	3.00e-58	221.00
IUUC-Aor-009926	Aspergillus oryzae	28.07	1.00e-57	219.00
IUUC-Ate-010274	Aspergillus terreus	33.44	2.00e-50	194.00
IUUC-Ame-011297	Astyanax mexicanus	70.53	0.00e+00	1406.00
IUUC-Bgr-012173	Blumeria graminis	31.48	4.00e-44	174.00
IUUC-Bta-013261	Bos taurus	97.23	0.00e+00	1932.00
IUUC-Bci-013971	Botrytis cinerea	32.84	2.00e-46	181.00
IUUC-Cja-019167	Callithrix jacchus	96.61	0.00e+00	1916.00
IUUC-Cfa-020287	Canis familiaris	96.71	0.00e+00	1913.00
IUUC-Cpo-022510	Cavia porcellus	94.48	0.00e+00	1822.00
IUUC-Csa-023474	Chlorocebus sabaeus	95.97	0.00e+00	1947.00
IUUC-Cho-024634	Choloepus hoffmanni	93.14	0.00e+00	787.00
IUUC-Cin-025642	Ciona intestinalis	32.87	1.00e-132	467.00
IUUC-Csv-025848	Ciona savignyi	44.66	2.00e-54	205.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	32.80	2.00e-44	175.00
IUUC-Cne-027088	Cryptococcus neoformans	27.80	1.00e-43	172.00
IUUC-Dre-028753	Danio rerio	71.81	0.00e+00	1397.00
IUUC-Dno-029733	Dasypus novemcinctus	94.86	0.00e+00	1868.00
IUUC-Dor-030781	Dipodomys ordii	97.46	0.00e+00	986.00
IUUC-Dme-031803	Drosophila melanogaster	34.58	2.00e-150	526.00
IUUC-Ete-032622	Echinops telfairi	87.89	0.00e+00	1702.00
IUUC-Eca-033344	Equus caballus	97.64	0.00e+00	1921.00
IUUC-Eeu-034523	Erinaceus europaeus	87.03	0.00e+00	1657.00
IUUC-Fca-035650	Felis catus	97.74	0.00e+00	1938.00
IUUC-Fal-037404	Ficedula albicollis	88.51	0.00e+00	1721.00
IUUC-Fox-037955	Fusarium oxysporum	33.81	2.00e-43	171.00
IUUC-Fso-038289	Fusarium solani	33.23	3.00e-47	184.00
IUUC-Gmo-038547	Gadus morhua	68.37	0.00e+00	1381.00
IUUC-Ggr-039858	Gaeumannomyces graminis	36.46	6.00e-43	170.00
IUUC-Gga-041030	Gallus gallus	88.60	0.00e+00	1732.00
IUUC-Gac-042581	Gasterosteus aculeatus	71.17	0.00e+00	1435.00
IUUC-Ggo-044641	Gorilla gorilla	97.74	0.00e+00	1942.00
IUUC-Hsa-046134	Homo sapiens	97.95	0.00e+00	1942.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	97.29	0.00e+00	756.00
IUUC-Kpa-049091	Komagataella pastoris	32.63	1.00e-45	179.00
IUUC-Lch-050288	Latimeria chalumnae	74.97	0.00e+00	1469.00
IUUC-Loc-052802	Lepisosteus oculatus	74.32	0.00e+00	1499.00
IUUC-Lma-053296	Leptosphaeria maculans	32.60	3.00e-48	187.00
IUUC-Laf-053997	Loxodonta africana	95.57	0.00e+00	1948.00
IUUC-Mcc-055855	Macaca mulatta	97.84	0.00e+00	1930.00
IUUC-Meu-056898	Macropus eugenii	95.20	0.00e+00	734.00
IUUC-Mor-056913	Magnaporthe oryzae	34.98	2.00e-42	168.00
IUUC-Mpo-057612	Magnaporthe poae	36.82	2.00e-43	171.00
IUUC-Mla-059097	Melampsora laricipopulina	30.37	1.00e-46	181.00
IUUC-Mga-059218	Meleagris gallopavo	88.61	0.00e+00	1698.00
IUUC-Mvi-060251	Microbotryum violaceum	31.60	1.00e-46	182.00
IUUC-Mmr-061093	Microcebus murinus	95.38	0.00e+00	1873.00
IUUC-Mdo-062757	Monodelphis domestica	92.98	0.00e+00	1823.00
IUUC-Mmu-063839	Mus musculus	94.26	0.00e+00	1922.00
IUUC-Mpu-065977	Mustela putorius furo	97.33	0.00e+00	1927.00
IUUC-Mlu-067460	Myotis lucifugus	95.27	0.00e+00	1918.00
IUUC-Nfi-068250	Neosartorya fischeri	34.57	4.00e-52	200.00
IUUC-Ncr-068710	Neurospora crassa	32.45	4.00e-45	177.00
IUUC-Nle-070011	Nomascus leucogenys	97.64	0.00e+00	1935.00
IUUC-Opr-070731	Ochotona princeps	90.76	0.00e+00	1759.00
IUUC-Ont-072165	Oreochromis niloticus	70.64	0.00e+00	1420.00
IUUC-Oan-072887	Ornithorhynchus anatinus	91.38	0.00e+00	1846.00
IUUC-Ocu-073926	Oryctolagus cuniculus	95.75	0.00e+00	1776.00
IUUC-Ola-087111	Oryzias latipes	67.87	0.00e+00	1354.00
IUUC-Oar-090291	Ovis aries	96.92	0.00e+00	1924.00
IUUC-Ptr-091044	Pan troglodytes	97.64	0.00e+00	1931.00
IUUC-Pan-092374	Papio anubis	95.77	0.00e+00	1942.00
IUUC-Psi-093170	Pelodiscus sinensis	55.83	0.00e+00	963.00
IUUC-Pma-094544	Petromyzon marinus	67.11	1.00e-170	592.00
IUUC-Pno-095068	Phaeosphaeria nodorum	30.56	2.00e-44	175.00
IUUC-Pfo-096480	Poecilia formosa	68.10	0.00e+00	1329.00
IUUC-Pab-098134	Pongo abelii	96.49	0.00e+00	1895.00
IUUC-Pca-100763	Procavia capensis	75.00	0.00e+00	990.00
IUUC-Pva-102544	Pteropus vampyrus	96.10	0.00e+00	1916.00
IUUC-Pgr-103257	Puccinia graminis	32.33	6.00e-50	193.00
IUUC-Ptt-103942	Puccinia triticina	31.55	2.00e-45	177.00
IUUC-Pte-104065	Pyrenophora teres	31.89	1.00e-45	179.00
IUUC-Rno-105468	Rattus norvegicus	92.70	0.00e+00	1751.00
IUUC-Sce-106356	Saccharomyces cerevisiae	27.75	3.00e-58	220.00
IUUC-Sha-106662	Sarcophilus harrisii	94.99	0.00e+00	1846.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	27.71	1.00e-71	265.00
IUUC-Spo-108265	Schizosaccharomyces pombe	28.55	4.00e-61	230.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	33.43	9.00e-46	179.00
IUUC-Sar-113525	Sorex araneus	93.89	0.00e+00	1083.00
IUUC-Sre-115163	Sporisorium reilianum	37.45	7.00e-41	162.00
IUUC-Ssc-115381	Sus scrofa	96.13	0.00e+00	1046.00
IUUC-Tgu-116525	Taeniopygia guttata	85.13	0.00e+00	1657.00
IUUC-Tru-118432	Takifugu rubripes	69.43	0.00e+00	1409.00
IUUC-Tsy-119306	Tarsius syrichta	81.02	0.00e+00	1255.00
IUUC-Tni-120757	Tetraodon nigroviridis	69.17	0.00e+00	1371.00
IUUC-Tre-122187	Trichoderma reesei	35.03	8.00e-48	186.00
IUUC-Tvi-122367	Trichoderma virens	35.35	2.00e-47	185.00
IUUC-Tme-126986	Tuber melanosporum	34.38	9.00e-54	206.00
IUUC-Tbe-127800	Tupaia belangeri	81.94	0.00e+00	1370.00
IUUC-Ttr-129154	Tursiops truncatus	88.60	0.00e+00	1699.00
IUUC-Uma-129366	Ustilago maydis	36.36	5.00e-40	160.00
IUUC-Vda-129827	Verticillium dahliae	33.54	5.00e-47	183.00
IUUC-Vpa-130493	Vicugna pacos	96.97	0.00e+00	1870.00
IUUC-Xtr-131941	Xenopus tropicalis	81.54	0.00e+00	1600.00
IUUC-Xma-133903	Xiphophorus maculatus	69.92	0.00e+00	1400.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence