iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068885

Ensembl Protein ID

ESA43483

UniProt Accession

V5IMY0; V5IMY0_NEUCR

Genbank Protein ID

ESA43483.1

Protein Name

Ubiquitin-activating enzyme E1 3

Genbank Nucleotide ID

CM002237

Gene Name

NCU03526

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU03526	ESA43483	ESA43483

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.90e-109	363.8	39	438

Active Site

Position(s)	Description	Evidence
205	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 8    wGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfk 108
           +G    +++k+a+vl+vGagg+GcEllKnLvl+G+g+++vvD dt+++snlnrqFLfr e+++ksKA va+ea++++np v+++ah+ +i++ + +i++f+
   Q: 39   LGRSLNANVKQARVLMVGAGGIGCELLKNLVLTGFGEVHVVDLDTIDLSNLNRQFLFRHEHIKKSKALVAKEAAQKFNPAVKIVAHHANIKDAQFNIEWFS 139
           68888999********************************************************************************************* PP
   S: 109  kfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa..vlfnklleeeageeevl 207
            f +V++aldn+earr+vn++cl+a+vpliesgt+G+ Gqv+vi kg+t+cy+c ++++ k++P+ct+++tp+++ h+i+w   +l+n++++ ++ e+   
   Q: 140  SFRIVFNALDNLEARRHVNKMCLAADVPLIESGTTGFNGQVQVIKKGVTACYDCAPKETPKSFPVCTIRSTPSQPIHCIVWGksYLLNEIFGASEDESAFD 240
           ************************************************************************************99999987665555544 PP
   S: 208  ekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv............sfcsnaealqvpekvekdeevv 296
             +d  + +e++++ ++++  ++ +n     e                + k f+ di + +++++++            ++   a++l  ++  ++ ++v 
   Q: 241  HTVDGDNAQEIEELKRESAALRKIRNSVGTEE-----------FAQMLFEKVFKTDIERLRSMEDMWktrkppeplnykELLDKAKSLDKDKVLKDAQKVW 330
           44444444444444433333332222222222...........2234456777777777888888885666665555553333344444444444444444 PP
   S: 297  kasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkf 392
           + +++      +l+ ++ + +e+k+  + + ++f+kdd++ +d+v+a an+r   +gi    ++++ik++agniipaiattna+v+Gl+++E++Kv++g++
   Q: 331  SLEENlvvfnDSLERLSKRVLENKSAGEESIITFDKDDEDTLDFVAASANIRSAVFGIDR-KSKFDIKQMAGNIIPAIATTNAIVAGLCVLEAFKVLKGHY 430
           44444444443333333333444444445578****************************.**************************************** PP
   S: 393  eplknffl 400
           e+ k++fl
   Q: 431  EQAKEVFL 438
           ****9997 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MDPAMGNPMV PMTAQIPAPV AQPIPLPVLT RDSYNSQSLG RSLNANVKQA RVLMVGAGGI 60
GCELLKNLVL TGFGEVHVVD LDTIDLSNLN RQFLFRHEHI KKSKALVAKE AAQKFNPAVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGTCTTGA CCTGGAAGGA ACTCCGGTCT GCCTGTCGCC GATTCAGCGC CTGGTGGTTG 60
CAACTTTTGA CTGCCTTCAG TTTGCATCCA CGAGGCTGAA CTTTTTCAAT TTCCGCTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR019572--UBA_E1_Cys
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF10585--UBA_e1_thiolCys

Gene Ontology

GO:0008641--F:small protein activating enzyme activity

KEGG

ncr:NCU03526

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	43.33	2.00e-106	377.00
IUUC-Aml-001662	Ailuropoda melanoleuca	41.17	8.00e-110	389.00
IUUC-Atr-002636	Amborella trichopoda	39.86	5.00e-111	393.00
IUUC-Apl-003369	Anas platyrhynchos	42.32	3.00e-99	353.00
IUUC-Aca-004490	Anolis carolinensis	42.71	1.00e-93	335.00
IUUC-Aly-006359	Arabidopsis lyrata	41.60	4.00e-100	357.00
IUUC-Ath-007667	Arabidopsis thaliana	41.41	4.00e-104	370.00
IUUC-Ago-007844	Ashbya gossypii	43.10	2.00e-107	380.00
IUUC-Acl-008270	Aspergillus clavatus	64.81	0.00e+00	663.00
IUUC-Afl-008674	Aspergillus flavus	56.00	0.00e+00	700.00
IUUC-Afu-008883	Aspergillus fumigatus	60.61	0.00e+00	673.00
IUUC-Ani-009500	Aspergillus nidulans	57.84	0.00e+00	716.00
IUUC-Ang-009535	Aspergillus niger	56.07	0.00e+00	677.00
IUUC-Aor-010223	Aspergillus oryzae	56.89	0.00e+00	689.00
IUUC-Ate-010282	Aspergillus terreus	54.18	1.00e-180	624.00
IUUC-Ame-011736	Astyanax mexicanus	45.10	8.00e-117	412.00
IUUC-Bgr-012166	Blumeria graminis	59.26	0.00e+00	704.00
IUUC-Bta-012589	Bos taurus	41.57	2.00e-111	394.00
IUUC-Bci-013802	Botrytis cinerea	62.11	0.00e+00	785.00
IUUC-Bdi-014697	Brachypodium distachyon	42.58	3.00e-105	374.00
IUUC-Bol-016315	Brassica oleracea	41.40	7.00e-105	372.00
IUUC-Bra-017009	Brassica rapa	37.25	9.00e-105	372.00
IUUC-Cel-018708	Caenorhabditis elegans	40.43	5.00e-100	356.00
IUUC-Cja-019120	Callithrix jacchus	40.44	1.00e-109	388.00
IUUC-Cfa-021061	Canis familiaris	41.06	3.00e-111	394.00
IUUC-Cpo-021842	Cavia porcellus	43.51	5.00e-109	386.00
IUUC-Csa-024104	Chlorocebus sabaeus	40.65	3.00e-109	387.00
IUUC-Cho-024332	Choloepus hoffmanni	43.06	4.00e-92	330.00
IUUC-Cin-025363	Ciona intestinalis	42.30	1.00e-105	375.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	68.99	0.00e+00	787.00
IUUC-Cne-026888	Cryptococcus neoformans	43.52	7.00e-104	369.00
IUUC-Cme-027315	Cyanidioschyzon merolae	33.46	2.00e-62	231.00
IUUC-Dre-028420	Danio rerio	44.18	5.00e-112	396.00
IUUC-Dno-030041	Dasypus novemcinctus	40.31	5.00e-109	386.00
IUUC-Dse-031504	Dothistroma septosporum	48.16	4.00e-161	559.00
IUUC-Dme-031771	Drosophila melanogaster	61.22	2.00e-66	244.00
IUUC-Ete-033037	Echinops telfairi	37.88	2.00e-94	338.00
IUUC-Eca-033774	Equus caballus	40.18	3.00e-102	364.00
IUUC-Eeu-035074	Erinaceus europaeus	36.07	1.00e-61	229.00
IUUC-Fca-036508	Felis catus	40.35	7.00e-103	366.00
IUUC-Fal-036813	Ficedula albicollis	42.45	9.00e-102	362.00
IUUC-Fox-038056	Fusarium oxysporum	64.80	0.00e+00	806.00
IUUC-Fso-038223	Fusarium solani	67.44	0.00e+00	786.00
IUUC-Gmo-038526	Gadus morhua	41.71	1.00e-101	362.00
IUUC-Ggr-039767	Gaeumannomyces graminis	65.93	0.00e+00	758.00
IUUC-Gga-040981	Gallus gallus	40.06	7.00e-105	372.00
IUUC-Gac-041437	Gasterosteus aculeatus	44.91	1.00e-117	414.00
IUUC-Gma-043041	Glycine max	39.96	7.00e-111	392.00
IUUC-Ggo-045358	Gorilla gorilla	43.50	7.00e-106	376.00
IUUC-Hsa-046068	Homo sapiens	40.61	9.00e-110	389.00
IUUC-Hvu-047646	Hordeum vulgare	42.76	1.00e-104	371.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	43.51	2.00e-109	387.00
IUUC-Kpa-049301	Komagataella pastoris	57.05	7.00e-45	172.00
IUUC-Lch-049565	Latimeria chalumnae	46.01	5.00e-119	419.00
IUUC-Lpe-050884	Leersia perrieri	43.11	3.00e-107	380.00
IUUC-Loc-052493	Lepisosteus oculatus	42.43	2.00e-119	421.00
IUUC-Lma-053117	Leptosphaeria maculans	61.98	8.00e-179	618.00
IUUC-Laf-054518	Loxodonta africana	43.10	1.00e-110	391.00
IUUC-Mcc-055334	Macaca mulatta	40.61	2.00e-109	388.00
IUUC-Mor-057137	Magnaporthe oryzae	64.50	0.00e+00	689.00
IUUC-Mpo-057449	Magnaporthe poae	64.02	0.00e+00	759.00
IUUC-Mtr-058045	Medicago truncatula	38.26	5.00e-112	396.00
IUUC-Mla-058864	Melampsora laricipopulina	44.82	6.00e-98	349.00
IUUC-Mga-059422	Meleagris gallopavo	37.12	1.00e-78	285.00
IUUC-Mvi-060536	Microbotryum violaceum	47.46	3.00e-115	407.00
IUUC-Mmr-061161	Microcebus murinus	39.63	3.00e-107	380.00
IUUC-Mdo-061802	Monodelphis domestica	40.99	5.00e-109	386.00
IUUC-Mmu-064357	Mus musculus	41.24	2.00e-116	410.00
IUUC-Mac-065475	Musa acuminata	41.31	3.00e-106	377.00
IUUC-Mpu-066895	Mustela putorius furo	41.23	2.00e-111	394.00
IUUC-Mlu-067862	Myotis lucifugus	41.30	1.00e-111	395.00
IUUC-Nfi-068385	Neosartorya fischeri	64.31	0.00e+00	700.00
IUUC-Nle-069524	Nomascus leucogenys	44.20	5.00e-109	386.00
IUUC-Opr-071038	Ochotona princeps	41.34	2.00e-118	417.00
IUUC-Ont-071719	Oreochromis niloticus	44.98	6.00e-116	409.00
IUUC-Oan-072877	Ornithorhynchus anatinus	40.28	2.00e-98	351.00
IUUC-Ocu-074080	Oryctolagus cuniculus	40.44	9.00e-110	389.00
IUUC-Oba-075936	Oryza barthii	41.17	2.00e-107	381.00
IUUC-Obr-076841	Oryza brachyantha	41.47	6.00e-107	379.00
IUUC-Ogl-077686	Oryza glaberrima	41.27	2.00e-109	387.00
IUUC-Ogu-078597	Oryza glumaepatula	40.00	7.00e-105	372.00
IUUC-Oin-079791	Oryza indica	41.17	2.00e-107	381.00
IUUC-Olo-081009	Oryza longistaminata	43.45	2.00e-107	381.00
IUUC-Ome-081327	Oryza meridionalis	39.64	3.00e-101	360.00
IUUC-Oni-082334	Oryza nivara	42.34	3.00e-105	374.00
IUUC-Opu-083447	Oryza punctata	43.11	2.00e-108	384.00
IUUC-Oru-084977	Oryza rufipogon	41.17	2.00e-107	381.00
IUUC-Osa-086160	Oryza sativa	46.00	1.00e-101	361.00
IUUC-Ola-087415	Oryzias latipes	40.16	3.00e-113	400.00
IUUC-Olu-087850	Ostreococcus lucimarinus	43.07	2.00e-111	394.00
IUUC-Oga-088434	Otolemur garnettii	40.44	3.00e-110	390.00
IUUC-Oar-089872	Ovis aries	40.56	7.00e-103	366.00
IUUC-Ptr-091212	Pan troglodytes	40.61	9.00e-110	389.00
IUUC-Pan-092708	Papio anubis	64.12	3.00e-66	244.00
IUUC-Psi-093703	Pelodiscus sinensis	43.21	1.00e-103	368.00
IUUC-Pno-094953	Phaeosphaeria nodorum	58.31	0.00e+00	645.00
IUUC-Ppa-095963	Physcomitrella patens	44.84	2.00e-104	371.00
IUUC-Pfo-097515	Poecilia formosa	48.87	4.00e-115	406.00
IUUC-Pab-097951	Pongo abelii	40.93	8.00e-83	299.00
IUUC-Pop-099703	Populus trichocarpa	38.87	4.00e-100	357.00
IUUC-Pca-100426	Procavia capensis	39.71	2.00e-111	394.00
IUUC-Ppe-101152	Prunus persica	42.86	3.00e-112	397.00
IUUC-Pva-102792	Pteropus vampyrus	39.38	6.00e-102	363.00
IUUC-Pgr-103592	Puccinia graminis	40.87	3.00e-114	404.00
IUUC-Ptt-103805	Puccinia triticina	39.89	2.00e-95	342.00
IUUC-Pte-104215	Pyrenophora teres	58.85	0.00e+00	684.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	59.55	0.00e+00	690.00
IUUC-Rno-106117	Rattus norvegicus	40.00	2.00e-118	418.00
IUUC-Sce-106177	Saccharomyces cerevisiae	39.26	3.00e-97	347.00
IUUC-Sha-107006	Sarcophilus harrisii	42.14	6.00e-110	389.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	50.09	2.00e-140	490.00
IUUC-Spo-108020	Schizosaccharomyces pombe	51.93	1.00e-131	461.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	62.20	0.00e+00	788.00
IUUC-Smo-108809	Selaginella moellendorffii	40.61	6.00e-99	352.00
IUUC-Sit-110581	Setaria italica	41.67	8.00e-108	382.00
IUUC-Sly-111870	Solanum lycopersicum	41.57	8.00e-109	385.00
IUUC-Stu-112283	Solanum tuberosum	42.80	8.00e-109	385.00
IUUC-Sar-113432	Sorex araneus	59.54	1.00e-43	169.00
IUUC-Sbi-114075	Sorghum bicolor	41.76	9.00e-108	382.00
IUUC-Sre-114926	Sporisorium reilianum	44.87	2.00e-135	474.00
IUUC-Ssc-116281	Sus scrofa	63.53	2.00e-65	239.00
IUUC-Tgu-117247	Taeniopygia guttata	38.50	3.00e-103	367.00
IUUC-Tru-118075	Takifugu rubripes	44.28	1.00e-102	365.00
IUUC-Tsy-119398	Tarsius syrichta	62.10	1.00e-43	169.00
IUUC-Tni-120771	Tetraodon nigroviridis	41.29	4.00e-85	306.00
IUUC-Tca-121651	Theobroma cacao	40.72	2.00e-112	398.00
IUUC-Tre-122224	Trichoderma reesei	66.99	0.00e+00	756.00
IUUC-Tvi-122634	Trichoderma virens	67.13	0.00e+00	766.00
IUUC-Tae-125665	Triticum aestivum	43.33	2.00e-105	374.00
IUUC-Tur-126417	Triticum urartu	42.80	4.00e-105	373.00
IUUC-Tme-127016	Tuber melanosporum	59.70	1.00e-168	584.00
IUUC-Tbe-127678	Tupaia belangeri	62.10	2.00e-43	168.00
IUUC-Ttr-128598	Tursiops truncatus	37.85	2.00e-101	361.00
IUUC-Uma-129612	Ustilago maydis	46.62	5.00e-123	433.00
IUUC-Vda-129811	Verticillium dahliae	64.95	0.00e+00	718.00
IUUC-Vpa-130732	Vicugna pacos	36.85	5.00e-70	256.00
IUUC-Vvi-130832	Vitis vinifera	41.23	3.00e-107	380.00
IUUC-Xtr-132823	Xenopus tropicalis	38.30	7.00e-99	352.00
IUUC-Xma-133552	Xiphophorus maculatus	48.42	5.00e-114	403.00
IUUC-Yli-134666	Yarrowia lipolytica	47.16	3.00e-120	424.00
IUUC-Zma-135547	Zea mays	42.89	9.00e-107	379.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence