iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106560

Ensembl Protein ID

ENSSHAP00000003185.1

UniProt Accession

G3VJ30; G3VJ30_SARHA

Genbank Protein ID

ENSSHAP00000003185

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01188505

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002812.1	ENSSHAT00000003221.1	ENSSHAP00000003185.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.52	0.00e+00	871.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

AKMVDTESQI CPLSPLDDDD LESPLSEEFL QEMGSIQEIS PSIGDDSSGA FGFTDYHCLG 60
SGPGSDGSVI TDTLSPASSP SSVNYAPVAG SVDDSSSATL NIECRICGDK ASGYHYGVHA 120

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Nucleotide Sequence
(Fasta)

GCCAAGATGG TGGACACTGA GAGCCAGATC TGCCCACTCT CTCCCCTGGA CGATGACGAT 60
CTGGAAAGCC CACTCTCGGA AGAGTTCCTC CAAGAGATGG GGAGCATCCA GGAGATCTCT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	91.08	0.00e+00	894.00
IUUC-Apl-003330	Anas platyrhynchos	87.55	0.00e+00	847.00
IUUC-Aca-004598	Anolis carolinensis	85.93	0.00e+00	828.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.30e-01	29.30
IUUC-Ame-011508	Astyanax mexicanus	73.83	0.00e+00	705.00
IUUC-Bta-012621	Bos taurus	92.54	0.00e+00	874.00
IUUC-Cja-019688	Callithrix jacchus	91.88	0.00e+00	868.00
IUUC-Cfa-020859	Canis familiaris	91.67	0.00e+00	895.00
IUUC-Cpo-021607	Cavia porcellus	85.47	0.00e+00	811.00
IUUC-Csa-023313	Chlorocebus sabaeus	91.88	0.00e+00	864.00
IUUC-Cho-024741	Choloepus hoffmanni	81.84	0.00e+00	739.00
IUUC-Dre-027446	Danio rerio	72.55	0.00e+00	690.00
IUUC-Dno-029173	Dasypus novemcinctus	90.62	0.00e+00	848.00
IUUC-Dor-030581	Dipodomys ordii	88.01	0.00e+00	801.00
IUUC-Dme-031794	Drosophila melanogaster	34.07	2.00e-56	214.00
IUUC-Ete-032330	Echinops telfairi	88.46	0.00e+00	853.00
IUUC-Eca-033712	Equus caballus	91.67	0.00e+00	858.00
IUUC-Fca-036555	Felis catus	91.53	0.00e+00	897.00
IUUC-Fal-036677	Ficedula albicollis	88.03	0.00e+00	843.00
IUUC-Gmo-039240	Gadus morhua	81.87	0.00e+00	644.00
IUUC-Gga-040473	Gallus gallus	88.25	0.00e+00	847.00
IUUC-Gac-041872	Gasterosteus aculeatus	72.09	0.00e+00	706.00
IUUC-Ggo-045226	Gorilla gorilla	92.52	0.00e+00	872.00
IUUC-Hsa-046893	Homo sapiens	92.52	0.00e+00	872.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	89.74	0.00e+00	847.00
IUUC-Lch-050116	Latimeria chalumnae	79.91	0.00e+00	772.00
IUUC-Loc-052131	Lepisosteus oculatus	82.75	0.00e+00	692.00
IUUC-Laf-054323	Loxodonta africana	91.88	0.00e+00	870.00
IUUC-Mcc-054841	Macaca mulatta	92.09	0.00e+00	865.00
IUUC-Meu-056833	Macropus eugenii	86.32	0.00e+00	783.00
IUUC-Mtr-058471	Medicago truncatula	29.82	2.00e-01	30.00
IUUC-Mga-059995	Meleagris gallopavo	79.24	0.00e+00	746.00
IUUC-Mdo-061954	Monodelphis domestica	93.33	0.00e+00	826.00
IUUC-Mmu-064295	Mus musculus	88.25	0.00e+00	812.00
IUUC-Mpu-066216	Mustela putorius furo	92.31	0.00e+00	904.00
IUUC-Nle-069970	Nomascus leucogenys	92.31	0.00e+00	870.00
IUUC-Ont-071594	Oreochromis niloticus	74.42	0.00e+00	706.00
IUUC-Oan-073501	Ornithorhynchus anatinus	91.44	0.00e+00	767.00
IUUC-Ocu-074634	Oryctolagus cuniculus	81.71	0.00e+00	811.00
IUUC-Oni-082926	Oryza nivara	30.19	1.60e-02	30.40
IUUC-Ola-086585	Oryzias latipes	80.16	0.00e+00	641.00
IUUC-Oga-088738	Otolemur garnettii	92.13	0.00e+00	865.00
IUUC-Oar-090453	Ovis aries	91.68	0.00e+00	870.00
IUUC-Ptr-091518	Pan troglodytes	92.31	0.00e+00	865.00
IUUC-Pan-092006	Papio anubis	92.31	0.00e+00	866.00
IUUC-Psi-093352	Pelodiscus sinensis	87.29	0.00e+00	853.00
IUUC-Pfo-096060	Poecilia formosa	73.21	0.00e+00	691.00
IUUC-Pab-098602	Pongo abelii	86.29	0.00e+00	773.00
IUUC-Pva-102175	Pteropus vampyrus	86.97	0.00e+00	837.00
IUUC-Rno-105283	Rattus norvegicus	88.68	0.00e+00	815.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	2.30e-02	30.40
IUUC-Smo-109075	Selaginella moellendorffii	30.00	8.60e-02	30.00
IUUC-Ssc-115266	Sus scrofa	91.67	0.00e+00	898.00
IUUC-Tgu-116778	Taeniopygia guttata	88.27	0.00e+00	847.00
IUUC-Tru-118436	Takifugu rubripes	72.94	0.00e+00	705.00
IUUC-Tsy-119642	Tarsius syrichta	97.40	7.00e-133	467.00
IUUC-Tni-119859	Tetraodon nigroviridis	73.15	0.00e+00	699.00
IUUC-Tvi-122624	Trichoderma virens	29.63	3.70e-01	27.30
IUUC-Tbe-127464	Tupaia belangeri	90.60	0.00e+00	882.00
IUUC-Ttr-129307	Tursiops truncatus	88.27	0.00e+00	820.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence