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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105632
UUCD1 version UUC-RaN-00697
Ensembl Protein ID ENSRNOP00000006115.3
UniProt Accession G3V6K9; G3V6K9_RAT
Genbank Protein ID EDL79624.1
Protein Name Recombination activating gene 1; Recombination-activating 1
Genbank Nucleotide ID AABR07053106
Gene Name Rag1; rCG_26191
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000004630.5 ENSRNOT00000006115.5 ENSRNOP00000006115.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 90.12 0.00e+00 1950.00 IUUC-Hsa-045964
E3 activity/RING/RING 96.35 0.00e+00 2076.00 IUUC-Mmu-064297
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MAVPLPSTLR LSSAPDEIQH PHIKFSEWKF KLFRVRSFEK APEEAQKEKD SSEGKPCLEQ 60
SPVVLDKPGG QNSVLTQRAL KLHPKFSKKF HVDGKSSDKA IHQARLRHFC RICGNHFKSD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105632|E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTGCTATCTC TGTGGCATCG AATATTAACA ACCAAACTGC AGACATTCTA ACACTCTGGC 60
CGGGAGGCCT GTGGAGCAAG GTAACTCTTG TGCTTTTCAT GCCTTGAGCC AAAATATTCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105632|E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF12940--RAG1
PF00097--zf-C3HC4
PF10426--zf-RAG1
SMART

SM00184--RING
Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination
KEGG rno:84600
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001206 Ailuropoda melanoleuca 89.26 0.00e+00 1904.00
IUUC-Apl-003271 Anas platyrhynchos 75.61 0.00e+00 1646.00
IUUC-Aca-004400 Anolis carolinensis 73.11 0.00e+00 1618.00
IUUC-Ame-011295 Astyanax mexicanus 59.02 0.00e+00 1216.00
IUUC-Bta-012421 Bos taurus 89.12 0.00e+00 1895.00
IUUC-Cja-019891 Callithrix jacchus 88.88 0.00e+00 1884.00
IUUC-Cfa-020740 Canis familiaris 81.50 0.00e+00 1768.00
IUUC-Cpo-021800 Cavia porcellus 88.91 0.00e+00 1839.00
IUUC-Csa-024203 Chlorocebus sabaeus 88.58 0.00e+00 1681.00
IUUC-Dre-028416 Danio rerio 59.10 0.00e+00 1215.00
IUUC-Dno-029101 Dasypus novemcinctus 87.73 0.00e+00 1862.00
IUUC-Eca-033385 Equus caballus 89.73 0.00e+00 1918.00
IUUC-Fca-036545 Felis catus 88.97 0.00e+00 1894.00
IUUC-Fal-037208 Ficedula albicollis 73.95 0.00e+00 1634.00
IUUC-Gmo-039622 Gadus morhua 55.14 0.00e+00 1177.00
IUUC-Gga-041182 Gallus gallus 74.95 0.00e+00 1595.00
IUUC-Gac-041682 Gasterosteus aculeatus 56.90 0.00e+00 1207.00
IUUC-Ggo-044510 Gorilla gorilla 90.03 0.00e+00 1914.00
IUUC-Hsa-045964 Homo sapiens 89.84 0.00e+00 1912.00
IUUC-Itr-048862 Ictidomys tridecemlineatus 89.45 0.00e+00 1896.00
IUUC-Lch-050041 Latimeria chalumnae 69.40 0.00e+00 1482.00
IUUC-Loc-052464 Lepisosteus oculatus 63.55 0.00e+00 1375.00
IUUC-Laf-053544 Loxodonta africana 88.11 0.00e+00 1884.00
IUUC-Mcc-054867 Macaca mulatta 89.55 0.00e+00 1905.00
IUUC-Meu-055986 Macropus eugenii 79.49 0.00e+00 1556.00
IUUC-Mga-059262 Meleagris gallopavo 75.34 0.00e+00 1610.00
IUUC-Mdo-062686 Monodelphis domestica 79.75 0.00e+00 1754.00
IUUC-Mmu-064297 Mus musculus 96.35 0.00e+00 2076.00
IUUC-Mpu-066027 Mustela putorius furo 88.78 0.00e+00 1866.00
IUUC-Mlu-067885 Myotis lucifugus 89.74 0.00e+00 1910.00
IUUC-Nle-070073 Nomascus leucogenys 89.55 0.00e+00 1906.00
IUUC-Ont-071400 Oreochromis niloticus 61.74 0.00e+00 1274.00
IUUC-Oan-072920 Ornithorhynchus anatinus 93.65 0.00e+00 777.00
IUUC-Ocu-074616 Oryctolagus cuniculus 89.54 0.00e+00 1894.00
IUUC-Ola-086828 Oryzias latipes 59.98 0.00e+00 1254.00
IUUC-Oga-088675 Otolemur garnettii 91.88 1.00e-151 528.00
IUUC-Oar-090380 Ovis aries 88.49 0.00e+00 1907.00
IUUC-Ptr-090648 Pan troglodytes 90.03 0.00e+00 1917.00
IUUC-Pan-092036 Papio anubis 89.36 0.00e+00 1902.00
IUUC-Psi-093130 Pelodiscus sinensis 78.25 0.00e+00 1719.00
IUUC-Pfo-097273 Poecilia formosa 60.04 0.00e+00 1226.00
IUUC-Pca-100134 Procavia capensis 82.85 0.00e+00 1747.00
IUUC-Sha-107238 Sarcophilus harrisii 80.04 0.00e+00 1762.00
IUUC-Sar-113591 Sorex araneus 77.01 0.00e+00 1609.00
IUUC-Ssc-115720 Sus scrofa 88.11 0.00e+00 1882.00
IUUC-Tgu-117030 Taeniopygia guttata 74.37 0.00e+00 1616.00
IUUC-Tru-117669 Takifugu rubripes 57.80 0.00e+00 1149.00
IUUC-Tsy-119578 Tarsius syrichta 85.33 0.00e+00 1836.00
IUUC-Tni-120073 Tetraodon nigroviridis 57.25 0.00e+00 1199.00
IUUC-Tbe-128029 Tupaia belangeri 82.19 0.00e+00 924.00
IUUC-Ttr-128677 Tursiops truncatus 91.57 0.00e+00 801.00
IUUC-Vpa-130346 Vicugna pacos 93.00 0.00e+00 874.00
IUUC-Xtr-132442 Xenopus tropicalis 87.11 7.00e-100 355.00
Created Date 25-Jun-2017

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