iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049578

Ensembl Protein ID

ENSLACP00000020611.1

UniProt Accession

H3BFE0; H3BFE0_LATCH

Genbank Protein ID

ENSLACP00000020611

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01022114

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000018112.1	ENSLACT00000020751.1	ENSLACP00000020611.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-31	105.4	913	947
UBD/Beta-Prp	4.10e-58	197.1	863	1066

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           ++v+c++  ++ t+ vsGs D+++++W+l tg+ +
   Q: 913  GEVRCVQViNEgTRAVSGSSDHSLRLWNLLTGKEV 947
           46*****88999*****************999876 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghed.svlslsfspsgdklvsGshdrtirvwdletgqclee 131
            +l g +++vt +++spd+++lv gs+D+   vw+l++ + +h+l+gh++ +v+++++  +g + vsGs+d  +r+w+l tg+++++
   Q: 863  TTLTGFKKGVTVLELSPDRSLLVAGSQDGRMMVWSLKDIEVIHILTGHSAgEVRCVQVINEGTRAVSGSSDHSLRLWNLLTGKEVYS 949
           67889999****************************************8659*********************************** PP
   S: 132  tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..v 215
           +++ h g    + ++ ++ + ++ +   ++v++W l+t++ l + +gg  d   ++++   g  l+s+s+ g + lwd  tge   +
   Q: 950  IQEDHAGYEVFALLQVETkKEMIYSVSGSQVNVWHLETAEPLFHISGGSPDVRMCMAVLGPGLPLISVSEGGLLSLWDSTTGERqgI 1036
           *****9877666666555566666666789*****************9***********99*******************9997666 PP
   S: 216  rtlng.htdnvksvrfspnderlvsgssDg 244
           + l g  ++ + ++++++n+ r+++g+  g
   Q: 1037 HCLDGmSDAAPACIAVLKNQGRIAVGNTNG 1066
           777774558899*******99999998766 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

YKTTGPCTSI IVLISKLFYR ERGLVSMVVD MRWGVRDVVA VDHKTTELCI KEIESCQRMS 60
VGPTFIALVG NRYGYRPIPR LIEHQEFEVL SSQLMCDESA CELLHDWFWK DENAVPPVYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACAAAACTA CGGGACCCTG TACCAGCATG TATGTAGACT AGAATAGTAC TGATTTCAAA 60
GCTGTTCTAC AGGGAACGTG GTTTAGTCTC CATGGTAACT GCATCCCAAA TGATAATTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR020472--G-protein_beta_WD-40_rep
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	47.82	0.00e+00	1417.00
IUUC-Apl-003467	Anas platyrhynchos	46.35	1.00e-59	222.00
IUUC-Ame-011400	Astyanax mexicanus	41.82	0.00e+00	1199.00
IUUC-Bta-013223	Bos taurus	48.21	0.00e+00	1261.00
IUUC-Cel-018404	Caenorhabditis elegans	32.47	5.00e-131	462.00
IUUC-Cja-018773	Callithrix jacchus	47.33	0.00e+00	857.00
IUUC-Cfa-020334	Canis familiaris	48.71	0.00e+00	1442.00
IUUC-Cpo-022316	Cavia porcellus	43.31	0.00e+00	1145.00
IUUC-Csa-023631	Chlorocebus sabaeus	47.17	0.00e+00	1394.00
IUUC-Cin-025646	Ciona intestinalis	35.83	2.00e-156	546.00
IUUC-Csv-026191	Ciona savignyi	29.10	2.00e-30	126.00
IUUC-Dre-028241	Danio rerio	41.02	0.00e+00	1116.00
IUUC-Dno-029990	Dasypus novemcinctus	47.75	3.00e-115	408.00
IUUC-Dor-030869	Dipodomys ordii	42.74	1.00e-109	390.00
IUUC-Ete-033059	Echinops telfairi	47.97	2.00e-130	460.00
IUUC-Eca-033718	Equus caballus	46.50	0.00e+00	1371.00
IUUC-Fca-035748	Felis catus	48.20	0.00e+00	1351.00
IUUC-Gac-041507	Gasterosteus aculeatus	38.28	0.00e+00	886.00
IUUC-Ggo-044551	Gorilla gorilla	45.39	0.00e+00	1324.00
IUUC-Hsa-046787	Homo sapiens	47.13	0.00e+00	1419.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	41.91	0.00e+00	719.00
IUUC-Loc-052039	Lepisosteus oculatus	53.68	0.00e+00	1670.00
IUUC-Laf-054240	Loxodonta africana	47.88	0.00e+00	1447.00
IUUC-Mcc-054657	Macaca mulatta	42.42	0.00e+00	1148.00
IUUC-Meu-056591	Macropus eugenii	50.05	0.00e+00	855.00
IUUC-Mmr-061577	Microcebus murinus	46.76	0.00e+00	1365.00
IUUC-Mdo-062895	Monodelphis domestica	51.36	0.00e+00	1402.00
IUUC-Mmu-063866	Mus musculus	46.30	0.00e+00	1336.00
IUUC-Mpu-066510	Mustela putorius furo	47.55	0.00e+00	1427.00
IUUC-Mlu-067855	Myotis lucifugus	47.59	0.00e+00	1360.00
IUUC-Nle-069557	Nomascus leucogenys	45.40	0.00e+00	1306.00
IUUC-Opr-071196	Ochotona princeps	41.01	7.00e-96	345.00
IUUC-Ont-072070	Oreochromis niloticus	38.59	0.00e+00	999.00
IUUC-Oan-073437	Ornithorhynchus anatinus	50.00	0.00e+00	1062.00
IUUC-Ocu-074941	Oryctolagus cuniculus	53.70	1.00e-32	132.00
IUUC-Ola-086624	Oryzias latipes	36.85	0.00e+00	891.00
IUUC-Oga-088313	Otolemur garnettii	48.27	0.00e+00	1298.00
IUUC-Oar-090123	Ovis aries	47.88	0.00e+00	1429.00
IUUC-Ptr-090552	Pan troglodytes	44.83	1.00e-164	574.00
IUUC-Psi-093963	Pelodiscus sinensis	54.66	0.00e+00	1620.00
IUUC-Pfo-096197	Poecilia formosa	37.51	0.00e+00	967.00
IUUC-Pab-097755	Pongo abelii	45.08	7.00e-140	490.00
IUUC-Pca-100809	Procavia capensis	47.59	0.00e+00	708.00
IUUC-Pva-102554	Pteropus vampyrus	45.74	0.00e+00	1179.00
IUUC-Rno-105174	Rattus norvegicus	42.01	0.00e+00	1119.00
IUUC-Sha-107304	Sarcophilus harrisii	51.15	0.00e+00	1558.00
IUUC-Sar-113168	Sorex araneus	46.52	1.00e-161	564.00
IUUC-Tru-118251	Takifugu rubripes	37.67	0.00e+00	800.00
IUUC-Tsy-119276	Tarsius syrichta	48.55	8.00e-66	246.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence