iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA
Protein-protein Interaction
IID	iRefIndex	PINA
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-22	78.8	17	45
UBD/Beta-Prp	6.50e-41	140.7	17	288

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDl 30
           + v+++++  d ++ v+++ D+t+k+W++
   Q: 17   GAVRAVRYnVDgNYCVTCGSDKTVKLWNP 45
           57999***9666***************96 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvs 111
           + +++v +  d+++++t + d+t+k+w+  + +ll+++sg  +ev +   s+d + ++ g+ Dr+  v+d++tgk+++ ++ h ++v +++f+++++++ s
   Q: 17   GAVRAVRYNVDGNYCVTCGSDKTVKLWNPLKSSLLKTYSGTGNEVLDAASSSDNSQIAAGGADRACTVFDVETGKQLRRWRTHGAQVNAVAFNEESSVVFS 117
           5677899999******************************************************************************************* PP
   S: 112  Gshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           Gs d t + +d +++++    ++++ ++ + ++ v++    +v+Gs+D+  r+++++ g++  +  g   dsv+s+sf++++++l++g + g v+l d ++
   Q: 118  GSMDCTMQAFDCRSRSEKPIqIFNESTDGILSIDVNG--HEIVAGSADGNYRVYSIRDGNMTVDYMG---DSVNSVSFTPDSNCLLAGVMGGIVRLIDKSS 213
           *************999988345555555555555555..99***********************977...******************************* PP
   S: 212  gecvrtlnghtdnvk..svrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse 285
           g+ + +++gh+++ +  + r+++  e+++sgs+Dg ++++ l  + ++++l+++ + + s ++ ++++  l+++++
   Q: 214  GKLLASYKGHQNTEYklDCRVLQSIEHVASGSEDGFVYVYSLLDSHIVSKLEHPSKVIHSLTA-HPKKERLMTAAG 288
           **********976551156777*******************************9976666666.888888877765 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSKCPTVRAR AIDCKQGAVR AVRYNVDGNY CVTCGSDKTV KLWNPLKSSL LKTYSGTGNE 60
VLDAASSSDN SQIAAGGADR ACTVFDVETG KQLRRWRTHG AQVNAVAFNE ESSVVFSGSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTAAAATGT CAAAATGCCC AACGGTTCGT GCAAGAGCAA TTGATTGTAA GCAAGGTGCA 60
GTACGTGCGG TTCGATATAA TGGTAAATTT GAAACAATAT ATTTTAATTC AATAAAGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0007165--P:signal transduction

KEGG

cel:CELE_F33G12.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002160	Ailuropoda melanoleuca	48.12	2.00e-84	304.00
IUUC-Atr-002647	Amborella trichopoda	40.07	6.00e-66	242.00
IUUC-Aca-004948	Anolis carolinensis	49.12	1.00e-83	301.00
IUUC-Aly-006489	Arabidopsis lyrata	41.26	3.00e-64	237.00
IUUC-Ath-007099	Arabidopsis thaliana	40.91	6.00e-64	236.00
IUUC-Acl-008374	Aspergillus clavatus	32.87	9.00e-37	145.00
IUUC-Afl-008506	Aspergillus flavus	33.79	1.00e-38	152.00
IUUC-Afu-009098	Aspergillus fumigatus	31.92	2.00e-31	129.00
IUUC-Ang-009705	Aspergillus niger	37.29	4.00e-36	144.00
IUUC-Aor-010031	Aspergillus oryzae	33.79	2.00e-38	151.00
IUUC-Ame-011056	Astyanax mexicanus	45.33	1.00e-76	278.00
IUUC-Bgr-012109	Blumeria graminis	33.09	1.00e-33	135.00
IUUC-Bta-012476	Bos taurus	48.81	9.00e-86	308.00
IUUC-Bci-013860	Botrytis cinerea	31.58	5.00e-31	127.00
IUUC-Bdi-014565	Brachypodium distachyon	44.17	1.00e-71	261.00
IUUC-Bol-016204	Brassica oleracea	41.61	1.00e-64	238.00
IUUC-Bra-018093	Brassica rapa	41.81	3.00e-65	240.00
IUUC-Cja-019279	Callithrix jacchus	48.61	5.00e-84	302.00
IUUC-Cfa-020516	Canis familiaris	47.78	1.00e-84	304.00
IUUC-Cpo-021427	Cavia porcellus	46.42	1.00e-80	291.00
IUUC-Cre-022775	Chlamydomonas reinhardtii	34.97	3.00e-51	194.00
IUUC-Csa-023449	Chlorocebus sabaeus	47.92	2.00e-83	300.00
IUUC-Cin-025637	Ciona intestinalis	46.92	8.00e-80	288.00
IUUC-Cgl-026458	Colletotrichum gloeosporioides	31.74	2.00e-35	141.00
IUUC-Cne-026994	Cryptococcus neoformans	30.48	9.00e-41	159.00
IUUC-Dre-028239	Danio rerio	47.28	4.00e-78	283.00
IUUC-Dno-029408	Dasypus novemcinctus	47.78	2.00e-84	304.00
IUUC-Dor-030684	Dipodomys ordii	41.84	2.00e-45	174.00
IUUC-Dse-031344	Dothistroma septosporum	36.94	6.00e-37	146.00
IUUC-Dme-031634	Drosophila melanogaster	42.81	5.00e-70	256.00
IUUC-Ete-033126	Echinops telfairi	44.03	6.00e-74	269.00
IUUC-Eca-034356	Equus caballus	44.03	5.00e-71	259.00
IUUC-Eeu-035196	Erinaceus europaeus	55.03	2.00e-48	184.00
IUUC-Fca-036231	Felis catus	48.46	4.00e-85	306.00
IUUC-Fox-038076	Fusarium oxysporum	30.39	2.00e-35	141.00
IUUC-Fso-038093	Fusarium solani	30.80	2.00e-28	118.00
IUUC-Gmo-039056	Gadus morhua	44.41	3.00e-73	266.00
IUUC-Ggr-039981	Gaeumannomyces graminis	35.04	2.00e-31	128.00
IUUC-Gga-041042	Gallus gallus	46.55	1.00e-81	295.00
IUUC-Gac-042638	Gasterosteus aculeatus	44.15	4.00e-74	270.00
IUUC-Gma-042723	Glycine max	42.40	7.00e-70	255.00
IUUC-Ggo-044720	Gorilla gorilla	48.26	1.00e-83	301.00
IUUC-Hsa-046056	Homo sapiens	48.61	5.00e-84	302.00
IUUC-Hvu-047675	Hordeum vulgare	38.82	5.00e-66	243.00
IUUC-Itr-048733	Ictidomys tridecemlineatus	47.93	2.00e-84	303.00
IUUC-Lch-050634	Latimeria chalumnae	48.07	9.00e-77	278.00
IUUC-Lpe-051470	Leersia perrieri	42.18	2.00e-71	260.00
IUUC-Loc-052452	Lepisosteus oculatus	44.64	7.00e-74	269.00
IUUC-Lma-053235	Leptosphaeria maculans	33.17	4.00e-19	87.40
IUUC-Laf-054315	Loxodonta africana	48.96	3.00e-84	303.00
IUUC-Mcc-054923	Macaca mulatta	47.57	8.00e-83	298.00
IUUC-Mor-056936	Magnaporthe oryzae	31.23	6.00e-31	126.00
IUUC-Mtr-058595	Medicago truncatula	42.40	5.00e-70	256.00
IUUC-Mla-058902	Melampsora laricipopulina	34.16	1.00e-45	175.00
IUUC-Mvi-060471	Microbotryum violaceum	36.65	7.00e-53	199.00
IUUC-Mmr-061665	Microcebus murinus	47.78	2.00e-84	304.00
IUUC-Mdo-062750	Monodelphis domestica	48.35	8.00e-75	271.00
IUUC-Mmu-063750	Mus musculus	48.46	1.00e-84	305.00
IUUC-Mac-065441	Musa acuminata	41.34	9.00e-68	248.00
IUUC-Mpu-066863	Mustela putorius furo	48.12	1.00e-84	305.00
IUUC-Mlu-067645	Myotis lucifugus	48.12	1.00e-84	305.00
IUUC-Nfi-068549	Neosartorya fischeri	35.86	1.00e-35	142.00
IUUC-Ncr-068816	Neurospora crassa	30.89	3.00e-22	98.20
IUUC-Nle-069457	Nomascus leucogenys	48.26	2.00e-83	301.00
IUUC-Ont-071674	Oreochromis niloticus	45.86	2.00e-70	258.00
IUUC-Oan-073391	Ornithorhynchus anatinus	46.42	2.00e-80	291.00
IUUC-Ocu-074186	Oryctolagus cuniculus	47.44	5.00e-80	289.00
IUUC-Oba-075414	Oryza barthii	42.80	1.00e-68	251.00
IUUC-Obr-076739	Oryza brachyantha	42.46	1.00e-70	258.00
IUUC-Ogl-076962	Oryza glaberrima	41.75	1.00e-70	258.00
IUUC-Ogu-078831	Oryza glumaepatula	42.46	6.00e-71	259.00
IUUC-Oin-079985	Oryza indica	42.11	7.00e-71	259.00
IUUC-Ome-081333	Oryza meridionalis	42.70	1.00e-68	251.00
IUUC-Oni-082558	Oryza nivara	42.11	8.00e-71	259.00
IUUC-Opu-084091	Oryza punctata	41.84	6.00e-71	259.00
IUUC-Oru-085253	Oryza rufipogon	42.21	2.00e-65	241.00
IUUC-Osa-086077	Oryza sativa	42.11	7.00e-71	259.00
IUUC-Ola-086946	Oryzias latipes	46.38	2.00e-76	277.00
IUUC-Olu-087604	Ostreococcus lucimarinus	35.64	2.00e-44	171.00
IUUC-Oga-088681	Otolemur garnettii	48.81	1.00e-84	305.00
IUUC-Oar-089913	Ovis aries	48.47	2.00e-85	307.00
IUUC-Ptr-091343	Pan troglodytes	47.95	6.00e-84	302.00
IUUC-Pan-092078	Papio anubis	47.92	2.00e-83	300.00
IUUC-Psi-093190	Pelodiscus sinensis	48.81	9.00e-86	308.00
IUUC-Pno-095078	Phaeosphaeria nodorum	28.77	5.00e-32	130.00
IUUC-Ppa-095777	Physcomitrella patens	39.52	6.00e-66	242.00
IUUC-Pfo-097153	Poecilia formosa	45.49	9.00e-74	268.00
IUUC-Pab-098307	Pongo abelii	47.40	2.00e-81	293.00
IUUC-Pop-099315	Populus trichocarpa	41.81	5.00e-66	243.00
IUUC-Pca-100538	Procavia capensis	47.76	7.00e-75	272.00
IUUC-Ppe-101632	Prunus persica	42.76	7.00e-70	255.00
IUUC-Pva-102484	Pteropus vampyrus	48.12	2.00e-84	304.00
IUUC-Pgr-103495	Puccinia graminis	34.14	6.00e-48	182.00
IUUC-Ptt-103975	Puccinia triticina	32.33	8.00e-46	176.00
IUUC-Pte-104354	Pyrenophora teres	28.04	4.00e-26	110.00
IUUC-Pyt-104692	Pyrenophora triticirepentis	27.72	5.00e-26	110.00
IUUC-Rno-105655	Rattus norvegicus	48.46	5.00e-84	302.00
IUUC-Sha-107130	Sarcophilus harrisii	42.44	2.00e-52	197.00
IUUC-Sja-107933	Schizosaccharomyces japonicus	35.86	1.00e-43	168.00
IUUC-Spo-108131	Schizosaccharomyces pombe	35.93	1.00e-45	175.00
IUUC-Ssl-108405	Sclerotinia sclerotiorum	31.25	2.00e-32	131.00
IUUC-Smo-109004	Selaginella moellendorffii	40.64	1.00e-59	221.00
IUUC-Sit-110508	Setaria italica	43.46	1.00e-71	261.00
IUUC-Sly-111093	Solanum lycopersicum	40.61	5.00e-62	229.00
IUUC-Stu-112380	Solanum tuberosum	40.61	8.00e-62	228.00
IUUC-Sar-113127	Sorex araneus	38.19	7.00e-26	109.00
IUUC-Sbi-114461	Sorghum bicolor	43.86	6.00e-72	262.00
IUUC-Sre-115020	Sporisorium reilianum	29.96	1.00e-27	117.00
IUUC-Ssc-115632	Sus scrofa	48.12	1.00e-84	304.00
IUUC-Tru-118039	Takifugu rubripes	43.43	2.00e-68	251.00
IUUC-Tsy-119239	Tarsius syrichta	55.77	2.00e-53	201.00
IUUC-Tni-120097	Tetraodon nigroviridis	44.19	1.00e-65	241.00
IUUC-Tca-121695	Theobroma cacao	41.81	5.00e-69	253.00
IUUC-Tre-122182	Trichoderma reesei	31.76	8.00e-34	136.00
IUUC-Tvi-122429	Trichoderma virens	32.87	8.00e-38	149.00
IUUC-Tae-125136	Triticum aestivum	43.30	1.00e-71	261.00
IUUC-Tur-126216	Triticum urartu	43.00	1.00e-71	261.00
IUUC-Tme-127030	Tuber melanosporum	38.17	1.00e-52	198.00
IUUC-Tbe-127686	Tupaia belangeri	53.98	2.00e-56	211.00
IUUC-Ttr-128770	Tursiops truncatus	47.78	1.00e-82	298.00
IUUC-Uma-129446	Ustilago maydis	28.39	2.00e-24	106.00
IUUC-Vda-129680	Verticillium dahliae	32.90	1.00e-28	118.00
IUUC-Vvi-131292	Vitis vinifera	42.76	1.00e-70	258.00
IUUC-Xtr-132204	Xenopus tropicalis	49.66	5.00e-83	299.00
IUUC-Xma-133727	Xiphophorus maculatus	44.48	6.00e-72	262.00
IUUC-Zma-135908	Zea mays	43.16	4.00e-65	239.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence