iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000014757.3	ENSXETT00000065892.1	ENSXETP00000063204.1
ENSXETG00000014757.3	ENSXETT00000032330.3	ENSXETP00000032330.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-93	314.5	1638	2019

Active Site

Position(s)	Description	Evidence
1986	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp........................ehl 68
           ++ le+++++E g++l G+t+ef+al+s+elq++dlgl++ +e       pnp+   + +                        ++ 
   Q: 1638 RAMLEIQYENEVGTGL-GPTLEFYALVSQELQRADLGLWRGEEVTL----PNPKGSQEGTkyihnlqglfalpfgrtakpahiaKVK 1719
           56899***********.**********************5555422....22222211112344458888889**********9999 PP
   S: 69   klFeflGrllgkalqdgrlldlplsksfyklllgkklsl..edleevdpelykslkeikena......es................. 130
             F+flG+l++ka++d rl+d+pl  +fyk +l+++ sl  +dl ++dp ++ks+  +++ +      e+                 
   Q: 1720 MKFRFLGKLMAKAIMDFRLVDIPLGLPFYKWMLRQESSLatHDLVNIDPVVAKSVYHLEDIVrqkkrlEQdkaqtkeslqfalesln 1806
           ***********************************877766**************99999986555551155555555533333333 PP
   S: 131  ....dieelgldltfsvseei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellsl 208
               ++e+            +     l+   + eLk gG+++pVt+ N+e+Yv+lv+ + l+eg+ +q+++fr+Gf++v+pl++l++
   Q: 1807 mngcSVED------------LgldftLPGFPNIELKKGGKDVPVTIHNLEDYVRLVIYWALNEGVSRQLDSFRDGFESVFPLNHLQY 1881
           33333333............2666668999********************************************************* PP
   S: 209  FteeelellicGe..eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPl..gGfaelkprlfvirk 291
           F +eel++l+cG+  + +dv++l + ++ ++gyt+ds+a+++++e+l++f++e+++ fLqFvTgs+rlP+   Gf++l+p l+++rk
   Q: 1882 FYPEELDQLLCGSraDPWDVKTLMECCRPDHGYTHDSRAVKFLFEILSSFDKEQQRLFLQFVTGSPRLPVgaIGFRSLNPPLTIVRK 1968
           ************98889*****************************************************656************** PP
   S: 292  .....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
                ++ dd lPs++TC+nyLkLP+Yss + ++ekLl+A +e+ ++F+ls
   Q: 1969 tfeatENPDDFLPSVMTCVNYLKLPDYSSIDNMREKLLMAAREGqQSFHLS 2019
           ***987888***************************************985 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MSSRPNNNPG GSLRRSQRNT AGAQPQEDTA GGSRGCSSSN LLPNPEDTER INTTDTQRPK 60
KDHVRGVKRS ASPDHSRTNS PSSAKKPKAL QHPEPSSGPR RPNNKPKKRQ GSQEQPFPSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAGCC GGCCTAATAA CAATCCAGGG GGGTCACTGC GACGTTCACA GAGGAACACT 60
GCTGGGGCCC AGCCGCAAGA GGACACTGCA GGAGGAAGGT GAGAAATTGG GTGTTGCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom
IPR004170--WWE-dom

PROSITE

PS50237--HECT
PS50918--WWE

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	37.99	3.00e-122	433.00
IUUC-Aml-001502	Ailuropoda melanoleuca	86.96	0.00e+00	3239.00
IUUC-Atr-002821	Amborella trichopoda	36.35	9.00e-113	402.00
IUUC-Apl-003531	Anas platyrhynchos	87.32	0.00e+00	3148.00
IUUC-Aly-005962	Arabidopsis lyrata	38.43	3.00e-111	397.00
IUUC-Ath-006636	Arabidopsis thaliana	44.38	2.00e-111	397.00
IUUC-Ago-007875	Ashbya gossypii	36.31	1.00e-80	295.00
IUUC-Acl-008242	Aspergillus clavatus	35.90	2.00e-112	401.00
IUUC-Afl-008736	Aspergillus flavus	39.82	3.00e-110	394.00
IUUC-Afu-008812	Aspergillus fumigatus	35.90	1.00e-113	405.00
IUUC-Ani-009407	Aspergillus nidulans	37.61	5.00e-111	396.00
IUUC-Ang-009763	Aspergillus niger	35.95	3.00e-105	377.00
IUUC-Aor-009941	Aspergillus oryzae	31.25	7.00e-113	402.00
IUUC-Ate-010459	Aspergillus terreus	33.33	1.00e-85	311.00
IUUC-Ame-011761	Astyanax mexicanus	85.44	0.00e+00	2849.00
IUUC-Bgr-012265	Blumeria graminis	35.05	7.00e-103	369.00
IUUC-Bta-013070	Bos taurus	86.98	0.00e+00	3255.00
IUUC-Bci-013890	Botrytis cinerea	39.56	3.00e-101	363.00
IUUC-Bdi-014046	Brachypodium distachyon	37.86	4.00e-119	423.00
IUUC-Bol-015942	Brassica oleracea	43.87	8.00e-112	399.00
IUUC-Bra-016849	Brassica rapa	40.89	3.00e-111	397.00
IUUC-Cja-019046	Callithrix jacchus	86.44	0.00e+00	3216.00
IUUC-Cfa-020521	Canis familiaris	84.64	0.00e+00	3118.00
IUUC-Cpo-021639	Cavia porcellus	83.31	0.00e+00	3130.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	39.16	3.00e-86	311.00
IUUC-Csa-023231	Chlorocebus sabaeus	86.67	0.00e+00	3233.00
IUUC-Cho-024380	Choloepus hoffmanni	85.45	0.00e+00	1961.00
IUUC-Cin-025482	Ciona intestinalis	51.39	4.00e-159	554.00
IUUC-Csv-026121	Ciona savignyi	48.11	0.00e+00	1514.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	34.83	2.00e-107	384.00
IUUC-Cne-026857	Cryptococcus neoformans	39.43	6.00e-91	329.00
IUUC-Cme-027226	Cyanidioschyzon merolae	35.13	1.00e-72	268.00
IUUC-Dre-028174	Danio rerio	85.35	0.00e+00	2899.00
IUUC-Dor-030939	Dipodomys ordii	81.10	0.00e+00	2579.00
IUUC-Dse-031444	Dothistroma septosporum	39.36	8.00e-104	372.00
IUUC-Dme-032162	Drosophila melanogaster	46.67	4.00e-161	563.00
IUUC-Ete-032345	Echinops telfairi	83.27	0.00e+00	2105.00
IUUC-Eca-033229	Equus caballus	86.57	0.00e+00	3180.00
IUUC-Eeu-035205	Erinaceus europaeus	78.76	0.00e+00	2813.00
IUUC-Fca-036444	Felis catus	86.44	0.00e+00	3200.00
IUUC-Fal-037131	Ficedula albicollis	85.84	0.00e+00	3220.00
IUUC-Fox-038035	Fusarium oxysporum	35.20	9.00e-106	377.00
IUUC-Fso-038320	Fusarium solani	35.50	6.00e-107	382.00
IUUC-Gmo-039497	Gadus morhua	80.02	0.00e+00	2974.00
IUUC-Ggr-040057	Gaeumannomyces graminis	34.90	1.00e-105	378.00
IUUC-Gga-041021	Gallus gallus	87.48	0.00e+00	3234.00
IUUC-Gac-042474	Gasterosteus aculeatus	80.25	0.00e+00	2959.00
IUUC-Gma-043060	Glycine max	38.53	1.00e-118	422.00
IUUC-Ggo-044855	Gorilla gorilla	86.34	0.00e+00	3212.00
IUUC-Hsa-046147	Homo sapiens	86.88	0.00e+00	3223.00
IUUC-Hvu-047775	Hordeum vulgare	37.85	6.00e-120	426.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	88.04	0.00e+00	3180.00
IUUC-Kpa-049098	Komagataella pastoris	37.75	5.00e-83	303.00
IUUC-Lch-049818	Latimeria chalumnae	82.84	0.00e+00	2934.00
IUUC-Lpe-051017	Leersia perrieri	37.22	4.00e-115	410.00
IUUC-Loc-051777	Lepisosteus oculatus	82.86	0.00e+00	3121.00
IUUC-Lma-052990	Leptosphaeria maculans	35.15	3.00e-109	390.00
IUUC-Laf-053727	Loxodonta africana	86.71	0.00e+00	3208.00
IUUC-Mcc-055799	Macaca mulatta	85.22	0.00e+00	3148.00
IUUC-Meu-056065	Macropus eugenii	89.02	0.00e+00	1969.00
IUUC-Mor-057054	Magnaporthe oryzae	37.91	2.00e-103	371.00
IUUC-Mpo-057417	Magnaporthe poae	38.23	1.00e-104	375.00
IUUC-Mtr-057849	Medicago truncatula	36.99	2.00e-110	394.00
IUUC-Mla-058870	Melampsora laricipopulina	41.80	2.00e-103	371.00
IUUC-Mga-059580	Meleagris gallopavo	87.03	0.00e+00	2781.00
IUUC-Mvi-060507	Microbotryum violaceum	40.75	2.00e-112	401.00
IUUC-Mmr-060816	Microcebus murinus	86.49	0.00e+00	3227.00
IUUC-Mdo-062866	Monodelphis domestica	83.24	0.00e+00	3028.00
IUUC-Mmu-063906	Mus musculus	87.83	0.00e+00	3229.00
IUUC-Mac-064675	Musa acuminata	38.43	4.00e-109	389.00
IUUC-Mpu-066199	Mustela putorius furo	85.47	0.00e+00	3128.00
IUUC-Mlu-067110	Myotis lucifugus	88.37	0.00e+00	3223.00
IUUC-Nfi-068482	Neosartorya fischeri	35.90	2.00e-113	404.00
IUUC-Ncr-068906	Neurospora crassa	37.94	1.00e-104	375.00
IUUC-Nle-069410	Nomascus leucogenys	86.14	0.00e+00	3203.00
IUUC-Opr-070401	Ochotona princeps	79.60	0.00e+00	1770.00
IUUC-Ont-072100	Oreochromis niloticus	79.64	0.00e+00	2969.00
IUUC-Oan-073121	Ornithorhynchus anatinus	87.06	0.00e+00	3303.00
IUUC-Ocu-074623	Oryctolagus cuniculus	84.25	0.00e+00	3169.00
IUUC-Oba-075380	Oryza barthii	36.85	5.00e-112	399.00
IUUC-Obr-076915	Oryza brachyantha	36.95	8.00e-117	415.00
IUUC-Ogl-077055	Oryza glaberrima	37.04	2.00e-115	411.00
IUUC-Ogu-078892	Oryza glumaepatula	40.39	7.00e-111	395.00
IUUC-Oin-079256	Oryza indica	36.87	3.00e-114	407.00
IUUC-Olo-080343	Oryza longistaminata	36.87	4.00e-114	406.00
IUUC-Ome-081422	Oryza meridionalis	36.73	2.00e-113	404.00
IUUC-Oni-083047	Oryza nivara	40.57	1.00e-112	401.00
IUUC-Opu-083641	Oryza punctata	36.26	7.00e-109	389.00
IUUC-Oru-084439	Oryza rufipogon	40.57	2.00e-111	397.00
IUUC-Osa-085972	Oryza sativa	37.04	1.00e-113	403.00
IUUC-Ola-087173	Oryzias latipes	80.65	0.00e+00	2959.00
IUUC-Olu-087871	Ostreococcus lucimarinus	35.59	3.00e-83	302.00
IUUC-Oga-087908	Otolemur garnettii	85.34	0.00e+00	3211.00
IUUC-Oar-090277	Ovis aries	87.78	0.00e+00	3272.00
IUUC-Ptr-091543	Pan troglodytes	86.88	0.00e+00	3226.00
IUUC-Pan-092243	Papio anubis	85.18	0.00e+00	3147.00
IUUC-Psi-093150	Pelodiscus sinensis	87.29	0.00e+00	3278.00
IUUC-Pno-094891	Phaeosphaeria nodorum	40.41	1.00e-109	391.00
IUUC-Ppa-095181	Physcomitrella patens	41.59	8.00e-105	374.00
IUUC-Pfo-096267	Poecilia formosa	79.36	0.00e+00	2954.00
IUUC-Pab-098072	Pongo abelii	86.42	0.00e+00	3214.00
IUUC-Pop-099190	Populus trichocarpa	39.83	2.00e-111	398.00
IUUC-Pca-100311	Procavia capensis	81.85	0.00e+00	2934.00
IUUC-Ppe-101284	Prunus persica	36.60	3.00e-111	397.00
IUUC-Pva-102215	Pteropus vampyrus	83.31	0.00e+00	1083.00
IUUC-Pgr-103694	Puccinia graminis	39.23	2.00e-101	364.00
IUUC-Ptt-103916	Puccinia triticina	38.46	5.00e-96	347.00
IUUC-Pte-104346	Pyrenophora teres	39.17	2.00e-107	384.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	39.42	6.00e-108	386.00
IUUC-Rno-105315	Rattus norvegicus	84.84	0.00e+00	3116.00
IUUC-Sce-106273	Saccharomyces cerevisiae	34.50	1.00e-69	258.00
IUUC-Sha-106835	Sarcophilus harrisii	85.90	0.00e+00	3297.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	37.63	2.00e-94	341.00
IUUC-Spo-108081	Schizosaccharomyces pombe	38.99	5.00e-94	340.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	39.96	5.00e-105	376.00
IUUC-Smo-109590	Selaginella moellendorffii	42.75	1.00e-108	389.00
IUUC-Sit-109757	Setaria italica	37.05	2.00e-116	414.00
IUUC-Sly-111469	Solanum lycopersicum	38.83	1.00e-118	421.00
IUUC-Stu-112896	Solanum tuberosum	35.99	3.00e-100	359.00
IUUC-Sar-113224	Sorex araneus	79.06	0.00e+00	1656.00
IUUC-Sbi-114313	Sorghum bicolor	37.16	2.00e-119	424.00
IUUC-Sre-114993	Sporisorium reilianum	33.00	5.00e-97	350.00
IUUC-Ssc-115535	Sus scrofa	84.77	0.00e+00	3115.00
IUUC-Tgu-117493	Taeniopygia guttata	86.53	0.00e+00	2508.00
IUUC-Tru-118669	Takifugu rubripes	78.96	0.00e+00	2906.00
IUUC-Tsy-119373	Tarsius syrichta	87.60	0.00e+00	1736.00
IUUC-Tni-120049	Tetraodon nigroviridis	76.60	0.00e+00	856.00
IUUC-Tca-121779	Theobroma cacao	37.24	4.00e-110	393.00
IUUC-Tre-122195	Trichoderma reesei	35.75	4.00e-104	373.00
IUUC-Tvi-122650	Trichoderma virens	35.83	1.00e-106	382.00
IUUC-Tae-123580	Triticum aestivum	37.75	5.00e-120	425.00
IUUC-Tur-126295	Triticum urartu	37.85	4.00e-122	433.00
IUUC-Tme-126964	Tuber melanosporum	40.12	3.00e-103	370.00
IUUC-Tbe-128149	Tupaia belangeri	78.68	0.00e+00	1176.00
IUUC-Ttr-128165	Tursiops truncatus	88.64	0.00e+00	2842.00
IUUC-Uma-129365	Ustilago maydis	35.59	1.00e-86	315.00
IUUC-Vda-129725	Verticillium dahliae	40.76	1.00e-105	378.00
IUUC-Vpa-130678	Vicugna pacos	89.47	0.00e+00	2471.00
IUUC-Vvi-131147	Vitis vinifera	37.73	2.00e-116	414.00
IUUC-Xma-133458	Xiphophorus maculatus	79.55	0.00e+00	2998.00
IUUC-Yli-134481	Yarrowia lipolytica	38.61	1.00e-94	341.00
IUUC-Zma-135782	Zea mays	36.88	6.00e-113	402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence