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Tag Content
iUUCD ID IUUC-Mdo-062515
Ensembl Protein ID ENSMODP00000036939.1
UniProt Accession F6RNA3; F6RNA3_MONDO
Protein Name Uncharacterized protein
Gene Name HCLS1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMODG00000018280.3 ENSMODT00000038535.2 ENSMODP00000036939.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.10e-10 41.4 403 454
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
    ++ ydy+++ +de ++ d+++ i e degW++g +g+ GlfP+n+v+ l
   Q: 403 IAVYDYQGEGSDEISFDPDDTITDI--EMIDEGWWRG--RCHGRFGLFPANYVQLL 454
    689*********************9..9*********..8*************976 PP
   

Organism Monodelphis domestica
Protein Sequence
(Fasta)
MWKSVVGHDV SVSVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRKE HINIHQLRNK 60
VSEEHDVLKK KEMEAGPKAS HGYGGRFGVE RDRMDKSALG HEYVADVEKH SSQTDAAKGF 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mdo-062515|UBD,SH3|Monodelphis domestica
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTGGAAGT CAGTGGTGGG GCATGATGTG TCTGTTTCTG TGGAAACACA AGGTGACGAC 60
TGGGACACAG ATCCTGACTT TGTAGTGAGT GTGGAAGTAT CACGGGCCCA AATAGGTAGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mdo-062515|UBD,SH3|Monodelphis domestica
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001194 Ailuropoda melanoleuca 66.60 1.00e-172 599.00
IUUC-Ame-011504 Astyanax mexicanus 45.86 5.00e-103 368.00
IUUC-Bta-012591 Bos taurus 71.23 1.00e-138 486.00
IUUC-Cja-019982 Callithrix jacchus 66.80 1.00e-168 586.00
IUUC-Cfa-020262 Canis familiaris 64.83 7.00e-163 566.00
IUUC-Cpo-021362 Cavia porcellus 91.06 9.00e-131 460.00
IUUC-Csa-023911 Chlorocebus sabaeus 67.48 6.00e-169 587.00
IUUC-Cin-025677 Ciona intestinalis 56.02 1.00e-66 247.00
IUUC-Dre-028127 Danio rerio 71.36 3.00e-93 335.00
IUUC-Dor-030437 Dipodomys ordii 57.37 4.00e-142 498.00
IUUC-Dme-031931 Drosophila melanogaster 51.92 3.00e-68 252.00
IUUC-Ete-033160 Echinops telfairi 60.71 3.00e-127 448.00
IUUC-Eca-033269 Equus caballus 66.47 2.00e-165 575.00
IUUC-Eeu-035032 Erinaceus europaeus 50.38 7.00e-86 311.00
IUUC-Fca-035999 Felis catus 65.61 3.00e-167 581.00
IUUC-Fal-037107 Ficedula albicollis 50.19 1.00e-121 429.00
IUUC-Gga-040335 Gallus gallus 67.49 3.00e-105 375.00
IUUC-Gac-042253 Gasterosteus aculeatus 68.08 3.00e-86 312.00
IUUC-Ggo-044505 Gorilla gorilla 68.71 1.00e-168 585.00
IUUC-Hsa-046728 Homo sapiens 72.42 3.00e-140 491.00
IUUC-Itr-048592 Ictidomys tridecemlineatus 70.13 3.00e-118 418.00
IUUC-Lch-050221 Latimeria chalumnae 76.85 2.00e-98 352.00
IUUC-Laf-054202 Loxodonta africana 65.03 2.00e-162 565.00
IUUC-Mcc-055824 Macaca mulatta 66.46 7.00e-163 566.00
IUUC-Mmr-061281 Microcebus murinus 62.50 6.00e-144 503.00
IUUC-Mmu-064341 Mus musculus 66.40 4.00e-166 577.00
IUUC-Mpu-066565 Mustela putorius furo 73.56 9.00e-132 463.00
IUUC-Mlu-066942 Myotis lucifugus 66.47 9.00e-162 563.00
IUUC-Nle-069436 Nomascus leucogenys 67.08 7.00e-168 583.00
IUUC-Opr-070288 Ochotona princeps 61.48 4.00e-136 478.00
IUUC-Ont-071712 Oreochromis niloticus 71.36 5.00e-89 322.00
IUUC-Ocu-074686 Oryctolagus cuniculus 66.06 8.00e-160 556.00
IUUC-Ola-086894 Oryzias latipes 57.34 3.00e-91 328.00
IUUC-Oga-088585 Otolemur garnettii 61.46 3.00e-155 541.00
IUUC-Oar-089686 Ovis aries 68.48 5.00e-174 603.00
IUUC-Ptr-090461 Pan troglodytes 72.98 4.00e-141 494.00
IUUC-Pan-091887 Papio anubis 67.56 1.00e-167 582.00
IUUC-Psi-093785 Pelodiscus sinensis 51.77 1.00e-141 496.00
IUUC-Pma-094161 Petromyzon marinus 61.73 1.00e-54 207.00
IUUC-Pfo-097391 Poecilia formosa 67.61 4.00e-88 318.00
IUUC-Pab-098222 Pongo abelii 66.67 3.00e-166 578.00
IUUC-Pca-100668 Procavia capensis 66.60 2.00e-159 555.00
IUUC-Pva-102767 Pteropus vampyrus 59.79 1.00e-134 473.00
IUUC-Rno-106001 Rattus norvegicus 67.21 9.00e-168 583.00
IUUC-Sha-106912 Sarcophilus harrisii 62.54 3.00e-151 528.00
IUUC-Sar-113338 Sorex araneus 59.59 5.00e-139 487.00
IUUC-Ssc-116027 Sus scrofa 67.52 9.00e-170 589.00
IUUC-Tgu-117472 Taeniopygia guttata 55.89 1.00e-142 499.00
Created Date 25-Jun-2017

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