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Tag Content
UUCD2 ID IUUC-Eca-033736
UUCD1 version UUC-EqC-01040
Ensembl Protein ID ENSECAP00000019479.1
UniProt Accession F6YAF4; F6YAF4_HORSE
Protein Name Ubiquitinyl hydrolase 1
Gene Name USP22
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSECAG00000021820.1 ENSECAT00000023514.1 ENSECAP00000019479.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.40e-93 312.6 121 464
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
    Gl NlgNtC+mN+++Q+L+++p lr+++l+ ++++++ + +p+ +l++++ +lf+e+++++++ p +ll+ +++ a+++ gyeqq
   Q: 121 GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHRCEMQ---SPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQ 205
    9*****************************.99999875...78********************************************* PP
   S: 91 DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
    Da+Efl ld l++++k ++ ++ +++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 206 DAHEFLIAALDVLHRHCKG----------------DDNGKKANNPNHCSCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGS 278
    *****************22................22335678899999**************************************** PP
   S: 180 eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
    ++ + +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++kklP v ++hLkRf +++ k r+k
   Q: 279 STPFWPlspgsegsvvngeshvsgttTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRK 365
    *877779***********************************************************************..5666899** PP
   S: 249 inkkvefpleLdlspfctspeekqke............kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevlee 325
    i+++v+fpleLd++pf++s++e+ + ++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD +t+ + e+vl
   Q: 366 ITTYVSFPLELDMTPFMASSKESRMNgqyqqpmdslnnDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIEDVLD- 453
    *******************5555444666666666666**************************************************. PP
   S: 326 tgstaYvlfYkrr 338
    s++Y+lfY+++
   Q: 454 --SEGYLLFYHKQ 464
    ..********985 PP
   

Organism Equus caballus
Protein Sequence
(Fasta)
QAKSCVCHVC GVHLNRLHSC LHCVFFGCFT KKHIHEHAKS KRHHLAIELM YGGIYCFLCQ 60
DYIYDKDMEI IAKEEQRKAW KMQGVGEKFS TWEPTKRELE LLKHNPKRRK ITSNCTIGLR 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Eca-033736|DUB,USP|Equus caballus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGGCAAAGT CGTGCGTCTG TCATGTTTGT GGTGTCCACC TGAACAGGCT TCACTCTTGC 60
CTCCACTGTG TCTTCTTCGG CTGTTTCACA AAGAAACATA TTCATGAACA TGCGAAGTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Eca-033736|DUB,USP|Equus caballus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0000124--C:SAGA complex
GO:0010485--F:H4 histone acetyltransferase activity
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:0016574--P:histone ubiquitination
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000393 Aegilops tauschii 37.85 1.00e-64 241.00
IUUC-Aml-001343 Ailuropoda melanoleuca 97.87 0.00e+00 966.00
IUUC-Atr-002653 Amborella trichopoda 39.39 4.00e-96 345.00
IUUC-Apl-003433 Anas platyrhynchos 92.36 0.00e+00 945.00
IUUC-Aca-005347 Anolis carolinensis 88.98 0.00e+00 931.00
IUUC-Ago-007811 Ashbya gossypii 31.57 6.00e-54 204.00
IUUC-Acl-008124 Aspergillus clavatus 32.29 1.00e-59 223.00
IUUC-Afl-008464 Aspergillus flavus 33.01 8.00e-55 207.00
IUUC-Afu-008912 Aspergillus fumigatus 31.86 2.00e-57 216.00
IUUC-Ani-009168 Aspergillus nidulans 33.02 2.00e-59 223.00
IUUC-Ang-009694 Aspergillus niger 31.88 7.00e-57 214.00
IUUC-Aor-010035 Aspergillus oryzae 35.21 1.00e-38 152.00
IUUC-Ate-010382 Aspergillus terreus 32.29 8.00e-53 200.00
IUUC-Ame-011253 Astyanax mexicanus 85.35 0.00e+00 835.00
IUUC-Bgr-012150 Blumeria graminis 31.20 2.00e-49 189.00
IUUC-Bta-013303 Bos taurus 98.29 0.00e+00 969.00
IUUC-Bci-013604 Botrytis cinerea 32.21 1.00e-57 217.00
IUUC-Bdi-014171 Brachypodium distachyon 35.15 5.00e-76 278.00
IUUC-Cja-019283 Callithrix jacchus 98.11 0.00e+00 879.00
IUUC-Cfa-021239 Canis familiaris 98.72 0.00e+00 973.00
IUUC-Cpo-022354 Cavia porcellus 97.01 0.00e+00 957.00
IUUC-Csa-023145 Chlorocebus sabaeus 97.87 0.00e+00 969.00
IUUC-Cho-024938 Choloepus hoffmanni 96.55 1.00e-65 243.00
IUUC-Cin-025109 Ciona intestinalis 57.56 7.00e-122 430.00
IUUC-Csv-026214 Ciona savignyi 57.26 4.00e-169 587.00
IUUC-Cgl-026457 Colletotrichum gloeosporioides 31.88 5.00e-55 208.00
IUUC-Cne-027085 Cryptococcus neoformans 32.36 5.00e-61 228.00
IUUC-Dre-027433 Danio rerio 93.16 0.00e+00 925.00
IUUC-Dno-030095 Dasypus novemcinctus 97.23 0.00e+00 964.00
IUUC-Dor-030481 Dipodomys ordii 96.53 2.00e-99 355.00
IUUC-Dse-031415 Dothistroma septosporum 32.37 3.00e-61 229.00
IUUC-Dme-032074 Drosophila melanogaster 52.75 7.00e-133 467.00
IUUC-Ete-033175 Echinops telfairi 76.54 4.00e-180 624.00
IUUC-Eeu-034814 Erinaceus europaeus 99.05 5.00e-123 434.00
IUUC-Fca-035861 Felis catus 98.93 0.00e+00 974.00
IUUC-Fal-037645 Ficedula albicollis 92.44 0.00e+00 929.00
IUUC-Fox-038046 Fusarium oxysporum 31.18 4.00e-55 208.00
IUUC-Fso-038321 Fusarium solani 33.03 5.00e-55 208.00
IUUC-Gmo-038474 Gadus morhua 93.92 6.00e-171 593.00
IUUC-Gga-040624 Gallus gallus 92.15 0.00e+00 942.00
IUUC-Gac-042197 Gasterosteus aculeatus 86.22 0.00e+00 857.00
IUUC-Gma-042897 Glycine max 33.96 6.00e-82 298.00
IUUC-Ggo-044409 Gorilla gorilla 97.87 0.00e+00 969.00
IUUC-Hsa-046521 Homo sapiens 97.87 0.00e+00 969.00
IUUC-Hvu-047739 Hordeum vulgare 38.95 7.00e-70 257.00
IUUC-Itr-048375 Ictidomys tridecemlineatus 97.23 0.00e+00 962.00
IUUC-Kpa-049135 Komagataella pastoris 35.36 7.00e-69 254.00
IUUC-Lch-050537 Latimeria chalumnae 94.24 0.00e+00 945.00
IUUC-Lpe-050969 Leersia perrieri 38.37 4.00e-73 268.00
IUUC-Loc-052765 Lepisosteus oculatus 82.93 0.00e+00 830.00
IUUC-Lma-053105 Leptosphaeria maculans 34.68 3.00e-66 246.00
IUUC-Laf-053571 Loxodonta africana 97.65 0.00e+00 965.00
IUUC-Mcc-055166 Macaca mulatta 97.87 0.00e+00 969.00
IUUC-Mor-057103 Magnaporthe oryzae 31.63 1.00e-56 213.00
IUUC-Mpo-057621 Magnaporthe poae 32.09 7.00e-56 211.00
IUUC-Mga-059709 Meleagris gallopavo 92.36 0.00e+00 945.00
IUUC-Mmr-060988 Microcebus murinus 97.87 0.00e+00 967.00
IUUC-Mdo-063065 Monodelphis domestica 95.10 0.00e+00 951.00
IUUC-Mmu-063829 Mus musculus 97.65 0.00e+00 967.00
IUUC-Mpu-066687 Mustela putorius furo 98.09 0.00e+00 965.00
IUUC-Nfi-068423 Neosartorya fischeri 31.86 2.00e-57 216.00
IUUC-Ncr-068809 Neurospora crassa 31.09 3.00e-58 219.00
IUUC-Nle-069261 Nomascus leucogenys 93.60 0.00e+00 914.00
IUUC-Opr-070469 Ochotona princeps 79.43 0.00e+00 685.00
IUUC-Ont-071961 Oreochromis niloticus 90.19 0.00e+00 896.00
IUUC-Oan-073565 Ornithorhynchus anatinus 85.58 0.00e+00 912.00
IUUC-Ocu-074435 Oryctolagus cuniculus 98.03 0.00e+00 939.00
IUUC-Oba-075688 Oryza barthii 35.99 5.00e-76 278.00
IUUC-Obr-076652 Oryza brachyantha 41.69 1.00e-74 273.00
IUUC-Ogl-077910 Oryza glaberrima 35.93 1.00e-78 286.00
IUUC-Ogu-078479 Oryza glumaepatula 35.93 1.00e-78 286.00
IUUC-Oin-079697 Oryza indica 39.66 5.00e-76 278.00
IUUC-Olo-080811 Oryza longistaminata 41.38 6.00e-53 200.00
IUUC-Ome-081706 Oryza meridionalis 35.89 5.00e-78 285.00
IUUC-Oni-083070 Oryza nivara 35.53 2.00e-78 286.00
IUUC-Opu-083605 Oryza punctata 40.16 8.00e-68 250.00
IUUC-Oru-084522 Oryza rufipogon 35.93 1.00e-78 286.00
IUUC-Osa-085351 Oryza sativa 39.36 1.00e-76 280.00
IUUC-Ola-086743 Oryzias latipes 88.56 0.00e+00 757.00
IUUC-Olu-087695 Ostreococcus lucimarinus 31.81 2.00e-50 192.00
IUUC-Oga-089131 Otolemur garnettii 94.23 0.00e+00 953.00
IUUC-Oar-089319 Ovis aries 98.50 0.00e+00 968.00
IUUC-Ptr-090783 Pan troglodytes 97.87 0.00e+00 971.00
IUUC-Pan-092927 Papio anubis 97.65 0.00e+00 967.00
IUUC-Psi-093670 Pelodiscus sinensis 92.34 0.00e+00 943.00
IUUC-Pma-094323 Petromyzon marinus 71.13 0.00e+00 717.00
IUUC-Pno-095141 Phaeosphaeria nodorum 32.95 5.00e-57 215.00
IUUC-Ppa-095413 Physcomitrella patens 41.36 1.00e-77 284.00
IUUC-Pfo-096462 Poecilia formosa 92.16 0.00e+00 921.00
IUUC-Pab-097612 Pongo abelii 98.08 0.00e+00 970.00
IUUC-Pte-104340 Pyrenophora teres 33.71 1.00e-59 223.00
IUUC-Pyt-104782 Pyrenophora triticirepentis 35.28 3.00e-67 249.00
IUUC-Rno-105247 Rattus norvegicus 97.65 0.00e+00 967.00
IUUC-Sce-106247 Saccharomyces cerevisiae 31.39 2.00e-52 199.00
IUUC-Sha-107538 Sarcophilus harrisii 95.85 2.00e-124 437.00
IUUC-Sja-107656 Schizosaccharomyces japonicus 34.69 2.00e-66 246.00
IUUC-Spo-108226 Schizosaccharomyces pombe 32.26 1.00e-60 226.00
IUUC-Ssl-108531 Sclerotinia sclerotiorum 32.35 1.00e-54 207.00
IUUC-Sit-109716 Setaria italica 35.43 3.00e-79 289.00
IUUC-Sar-113341 Sorex araneus 86.76 0.00e+00 759.00
IUUC-Sbi-114205 Sorghum bicolor 34.94 8.00e-80 291.00
IUUC-Tgu-116938 Taeniopygia guttata 95.31 0.00e+00 954.00
IUUC-Tru-117622 Takifugu rubripes 89.26 0.00e+00 912.00
IUUC-Tsy-119431 Tarsius syrichta 85.90 0.00e+00 813.00
IUUC-Tni-120661 Tetraodon nigroviridis 91.90 0.00e+00 923.00
IUUC-Tre-122139 Trichoderma reesei 31.44 4.00e-54 205.00
IUUC-Tae-125608 Triticum aestivum 35.35 1.00e-85 310.00
IUUC-Tme-127115 Tuber melanosporum 38.48 4.00e-81 295.00
IUUC-Ttr-129018 Tursiops truncatus 95.13 0.00e+00 818.00
IUUC-Uma-129455 Ustilago maydis 31.93 5.00e-33 136.00
IUUC-Vda-129829 Verticillium dahliae 32.89 3.00e-35 141.00
IUUC-Xtr-132444 Xenopus tropicalis 91.12 0.00e+00 933.00
IUUC-Xma-133514 Xiphophorus maculatus 92.75 0.00e+00 928.00
IUUC-Yli-134357 Yarrowia lipolytica 30.81 3.00e-48 186.00
Created Date 25-Jun-2017

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