iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054466

Ensembl Protein ID

ENSLAFP00000000803.4

UniProt Accession

G3SMN9; G3SMN9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

SIK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000960.4	ENSLAFT00000000961.4	ENSLAFP00000000803.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	78.95	0.00e+00	1098.00	IUUC-Hsa-046775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MVIMSEFSTA AVGSGQGQQK PLRVGFYDIE RTLGKGNFAV VKLARHRVTK TQVAIKIIDK 60
TRLDPSNLEK IYREVQIMKL LNHPHIIKLY QVMETKDMLY IVTEFAKNGE MFDYLTSNGH 120

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Nucleotide Sequence
(Fasta)

ATGGTGATCA TGTCGGAGTT CAGCACCGCG GCGGTGGGCT CAGGCCAGGG CCAGCAGAAG 60
CCCCTCCGGG TGGGCTTTTA CGACATCGAG CGAACCCTGG GCAAAGGCAA TTTCGCAGTA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR034672--SIK
IPR015940--UBA

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0043276--P:anoikis
GO:0055007--P:cardiac muscle cell differentiation
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0035556--P:intracellular signal transduction
GO:0032792--P:negative regulation of CREB transcription factor activity
GO:0045721--P:negative regulation of gluconeogenesis
GO:0010868--P:negative regulation of triglyceride biosynthetic process
GO:0007346--P:regulation of mitotic cell cycle
GO:0010830--P:regulation of myotube differentiation

KEGG

lav:100671882

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001538	Ailuropoda melanoleuca	47.17	3.00e-124	439.00
IUUC-Aca-004739	Anolis carolinensis	68.14	0.00e+00	948.00
IUUC-Ame-011603	Astyanax mexicanus	65.62	0.00e+00	773.00
IUUC-Cja-019873	Callithrix jacchus	76.31	0.00e+00	1050.00
IUUC-Cfa-020801	Canis familiaris	77.79	0.00e+00	983.00
IUUC-Cpo-022296	Cavia porcellus	81.98	0.00e+00	915.00
IUUC-Csa-023676	Chlorocebus sabaeus	76.12	0.00e+00	1031.00
IUUC-Cho-025021	Choloepus hoffmanni	73.52	7.00e-150	524.00
IUUC-Cin-025762	Ciona intestinalis	64.46	6.00e-128	451.00
IUUC-Csv-026013	Ciona savignyi	57.91	2.00e-118	418.00
IUUC-Dre-028021	Danio rerio	64.13	0.00e+00	741.00
IUUC-Dno-029103	Dasypus novemcinctus	73.89	0.00e+00	769.00
IUUC-Dme-031957	Drosophila melanogaster	64.63	4.00e-129	456.00
IUUC-Ete-033190	Echinops telfairi	86.76	0.00e+00	743.00
IUUC-Eca-033614	Equus caballus	58.33	4.00e-111	396.00
IUUC-Gmo-039423	Gadus morhua	62.04	0.00e+00	747.00
IUUC-Gga-040174	Gallus gallus	68.78	0.00e+00	930.00
IUUC-Gac-041875	Gasterosteus aculeatus	72.24	4.00e-155	541.00
IUUC-Ggo-045090	Gorilla gorilla	77.06	0.00e+00	1055.00
IUUC-Hsa-046775	Homo sapiens	77.93	0.00e+00	1045.00
IUUC-Itr-048715	Ictidomys tridecemlineatus	77.67	0.00e+00	1037.00
IUUC-Lch-049933	Latimeria chalumnae	59.26	0.00e+00	799.00
IUUC-Loc-052048	Lepisosteus oculatus	67.69	0.00e+00	784.00
IUUC-Mcc-054655	Macaca mulatta	76.75	0.00e+00	1040.00
IUUC-Meu-056705	Macropus eugenii	73.33	0.00e+00	788.00
IUUC-Mmr-061419	Microcebus murinus	79.60	0.00e+00	983.00
IUUC-Mdo-062854	Monodelphis domestica	68.21	0.00e+00	905.00
IUUC-Mmu-064252	Mus musculus	74.06	0.00e+00	1108.00
IUUC-Nle-069329	Nomascus leucogenys	74.22	0.00e+00	972.00
IUUC-Opr-071101	Ochotona princeps	60.41	5.00e-178	617.00
IUUC-Ont-071887	Oreochromis niloticus	60.31	0.00e+00	716.00
IUUC-Oan-073050	Ornithorhynchus anatinus	76.52	0.00e+00	879.00
IUUC-Oga-088220	Otolemur garnettii	75.81	0.00e+00	1048.00
IUUC-Oar-089420	Ovis aries	71.28	0.00e+00	898.00
IUUC-Ptr-091258	Pan troglodytes	77.94	0.00e+00	1043.00
IUUC-Pan-092031	Papio anubis	76.75	0.00e+00	1040.00
IUUC-Pfo-097451	Poecilia formosa	63.99	0.00e+00	724.00
IUUC-Pab-097806	Pongo abelii	77.44	0.00e+00	1040.00
IUUC-Pva-102182	Pteropus vampyrus	72.95	0.00e+00	714.00
IUUC-Sha-107262	Sarcophilus harrisii	69.75	0.00e+00	981.00
IUUC-Ssc-115584	Sus scrofa	94.76	5.00e-142	496.00
IUUC-Tgu-116973	Taeniopygia guttata	67.81	0.00e+00	919.00
IUUC-Tru-117598	Takifugu rubripes	60.84	3.00e-117	416.00
IUUC-Tsy-119567	Tarsius syrichta	45.26	5.00e-115	408.00
IUUC-Tni-120589	Tetraodon nigroviridis	60.54	3.00e-118	419.00
IUUC-Tbe-127501	Tupaia belangeri	59.48	8.00e-124	438.00
IUUC-Ttr-128365	Tursiops truncatus	78.16	0.00e+00	811.00
IUUC-Xtr-131848	Xenopus tropicalis	60.26	5.00e-113	402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence