iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001720

Ensembl Protein ID

ENSAMEP00000001524.1

UniProt Accession

D2GYZ4; D2GYZ4_AILME

Genbank Protein ID

EFB14045.1

Protein Name

Putative uncharacterized protein

Genbank Nucleotide ID

ACTA01066657

Gene Name

PHF1; PANDA_002265

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000001427.1	ENSAMET00000001582.1	ENSAMEP00000001524.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.20e-10	39.4	89	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek.slveCekCrewfHpaClklsveeelpnsek.wiCpkCr 52
            C vC++++      lv CekCr+++H++C+ + +  + +++ + w C++C 
   Q: 89   LCCVCRSETVVPGnRLVSCEKCRHAYHQDCHVPRAPAPGEGEGTsWVCRQCV 140
           588***999876459*******************66666655558******7 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAQPPRLSRS GAPPLWDPAS PAPTSGPRPR LWEGQDVLAR WTDGLLYLGT IKKVDSAREV 60
CLVQFEDDSQ FLVLWKDISP AALPGEELLC CVCRSETVVP GNRLVSCEKC RHAYHQDCHV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCACAGC CCCCCCGGCT GAGCCGCTCT GGTGCCCCCC CACTTTGGGA CCCAGCCTCC 60
CCTGCTCCCA CCTCAGGCCC CAGGCCTCGG CTTTGGGAGG GTCAAGATGT GCTGGCCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025894--Mtf2_C_dom
IPR031202--PHF1
IPR002999--Tudor
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF14061--Mtf2_C
PF00628--PHD

SMART

SM00249--PHD
SM00333--TUDOR

Gene Ontology

GO:0035098--C:ESC/E(Z) complex
GO:0035861--C:site of double-strand break
GO:0008270--F:zinc ion binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0061086--P:negative regulation of histone H3-K27 methylation
GO:0061087--P:positive regulation of histone H3-K27 methylation

KEGG

aml:100472996

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011369	Astyanax mexicanus	47.97	3.00e-127	448.00
IUUC-Bta-012536	Bos taurus	98.24	0.00e+00	907.00
IUUC-Cja-019049	Callithrix jacchus	97.88	0.00e+00	919.00
IUUC-Cfa-021211	Canis familiaris	98.77	0.00e+00	945.00
IUUC-Cpo-021980	Cavia porcellus	95.08	0.00e+00	917.00
IUUC-Csa-023154	Chlorocebus sabaeus	97.18	0.00e+00	943.00
IUUC-Dre-028597	Danio rerio	48.16	4.00e-132	464.00
IUUC-Dor-030431	Dipodomys ordii	95.95	0.00e+00	880.00
IUUC-Ete-032589	Echinops telfairi	91.10	0.00e+00	911.00
IUUC-Eca-034315	Equus caballus	99.12	0.00e+00	976.00
IUUC-Gmo-039382	Gadus morhua	64.69	3.00e-119	421.00
IUUC-Gac-041748	Gasterosteus aculeatus	65.52	1.00e-121	429.00
IUUC-Ggo-044966	Gorilla gorilla	97.88	0.00e+00	940.00
IUUC-Hsa-046188	Homo sapiens	97.53	0.00e+00	907.00
IUUC-Itr-048249	Ictidomys tridecemlineatus	96.65	0.00e+00	927.00
IUUC-Lch-050336	Latimeria chalumnae	53.10	5.00e-150	524.00
IUUC-Laf-053729	Loxodonta africana	93.18	0.00e+00	875.00
IUUC-Mcc-055486	Macaca mulatta	97.18	0.00e+00	943.00
IUUC-Meu-055933	Macropus eugenii	84.76	0.00e+00	763.00
IUUC-Mmr-061114	Microcebus murinus	96.65	0.00e+00	948.00
IUUC-Mdo-062033	Monodelphis domestica	83.30	0.00e+00	792.00
IUUC-Mmu-063482	Mus musculus	92.59	0.00e+00	944.00
IUUC-Mpu-065725	Mustela putorius furo	98.77	0.00e+00	961.00
IUUC-Mlu-067243	Myotis lucifugus	95.94	0.00e+00	939.00
IUUC-Nle-069759	Nomascus leucogenys	97.35	0.00e+00	912.00
IUUC-Ont-071655	Oreochromis niloticus	53.30	2.00e-125	442.00
IUUC-Ocu-073930	Oryctolagus cuniculus	97.88	0.00e+00	922.00
IUUC-Oga-088161	Otolemur garnettii	95.41	0.00e+00	922.00
IUUC-Oar-089582	Ovis aries	97.89	0.00e+00	900.00
IUUC-Ptr-090810	Pan troglodytes	97.71	0.00e+00	961.00
IUUC-Pan-091980	Papio anubis	97.18	0.00e+00	943.00
IUUC-Pfo-097260	Poecilia formosa	61.30	3.00e-123	434.00
IUUC-Pab-098556	Pongo abelii	97.53	0.00e+00	916.00
IUUC-Pca-100360	Procavia capensis	96.66	0.00e+00	840.00
IUUC-Pva-102900	Pteropus vampyrus	97.88	0.00e+00	920.00
IUUC-Rno-105536	Rattus norvegicus	93.65	0.00e+00	928.00
IUUC-Sha-107357	Sarcophilus harrisii	85.64	0.00e+00	841.00
IUUC-Ssc-116070	Sus scrofa	96.47	0.00e+00	882.00
IUUC-Tsy-119247	Tarsius syrichta	98.73	0.00e+00	636.00
IUUC-Tbe-127780	Tupaia belangeri	91.53	0.00e+00	852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence