iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062671

Ensembl Protein ID

ENSMODP00000005121.2

UniProt Accession

F6R9Z4; F6R9Z4_MONDO

Protein Name

Uncharacterized protein

Gene Name

PLAA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000004155.3	ENSMODT00000005231.3	ENSMODP00000005121.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-26	90.0	149	179
UBD/Beta-Prp	5.00e-64	216.5	33	298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D+tik+W 
   Q: 149  GHTAAVWAVKIlPEqGLMLTGSADKTIKLWK 179
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
             +++ srd+t+++w   +++     ++++sgh+++v++v+++p+++     +++tg++D++i+++ l+++ ++++lkgh+++v+sls+
   Q: 33   A-FVSVSRDRTTRLWAPNSPNRgfteMHCMSGHSNFVSCVCIIPSSDiyprgLIATGGNDHNICIFTLDSSAPLYILKGHKNTVCSLSS 120
           4.78899************99999***********************999999************************************ PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsn 191
            +   +l+sGs+d t++vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+t++lW  k g++ rt++g h+d v+ l++  +
   Q: 121  GK-FGTLLSGSWDTTAKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLW--KAGRCERTFSG-HEDCVRGLAILNE 202
           *9.9***************..9******.*********************************..88********9.*********9986 PP
   S: 192  gkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvl 280
            +e++s+++d +++ w++ tgec++ + ght+ ++s+ ++pn + +v++++D+s+riW  + g++ +t+ l+++s+++++v  +++  +
   Q: 203  -TEFLSCANDASIRRWQI-TGECLEVYYGHTNYIYSISVFPNCKDFVTTAEDRSLRIW--KRGECAQTIRLPAQSIWCCCV--LENGDI 285
           .8****************.***************************************..9********************..99**** PP
   S: 281  vlgsedskvniwk 293
           v g++d++++++ 
   Q: 286  VVGASDGIIRVFT 298
           ***********97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MASGGGRYRL SCSLLGHELD VRGVVAGLYP PGAFVSVSRD RTTRLWAPNS PNRGFTEMHC 60
MSGHSNFVSC VCIIPSSDIY PRGLIATGGN DHNICIFTLD SSAPLYILKG HKNTVCSLSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTGTGGTG GTGCTTTCAA GAGTAATAGG GAATTTAGAA TGAGAGTTTG GAGGGAGATA 60
ATGAGTTCTG TTCTGGAGAA CAGCTTTTAA CATGTCTAAG GGTCGTCCAA TTCGAAATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0016005--F:phospholipase A2 activator activity
GO:0043130--F:ubiquitin binding
GO:0006954--P:inflammatory response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010992--P:ubiquitin homeostasis

KEGG

mdo:100016171

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	30.58	1.00e-89	323.00
IUUC-Aml-002125	Ailuropoda melanoleuca	88.38	0.00e+00	1468.00
IUUC-Atr-002554	Amborella trichopoda	31.15	2.00e-95	343.00
IUUC-Apl-004094	Anas platyrhynchos	82.49	0.00e+00	1279.00
IUUC-Aca-004726	Anolis carolinensis	82.04	0.00e+00	1355.00
IUUC-Aly-005961	Arabidopsis lyrata	33.04	1.00e-108	387.00
IUUC-Ath-006639	Arabidopsis thaliana	32.65	1.00e-104	374.00
IUUC-Ago-007772	Ashbya gossypii	37.28	3.00e-76	280.00
IUUC-Acl-008316	Aspergillus clavatus	32.33	7.00e-87	315.00
IUUC-Afl-008532	Aspergillus flavus	33.12	2.00e-89	323.00
IUUC-Afu-008950	Aspergillus fumigatus	32.78	2.00e-88	320.00
IUUC-Ani-009186	Aspergillus nidulans	34.21	7.00e-94	338.00
IUUC-Ang-009575	Aspergillus niger	32.84	2.00e-87	317.00
IUUC-Aor-010086	Aspergillus oryzae	33.12	2.00e-89	323.00
IUUC-Ate-010541	Aspergillus terreus	31.37	2.00e-83	303.00
IUUC-Ame-011633	Astyanax mexicanus	66.12	0.00e+00	1100.00
IUUC-Bgr-012292	Blumeria graminis	29.95	2.00e-90	326.00
IUUC-Bta-013218	Bos taurus	87.95	0.00e+00	1466.00
IUUC-Bci-013876	Botrytis cinerea	32.27	2.00e-91	330.00
IUUC-Bdi-014810	Brachypodium distachyon	33.03	3.00e-105	375.00
IUUC-Bol-016006	Brassica oleracea	33.64	9.00e-109	387.00
IUUC-Bra-017593	Brassica rapa	33.90	2.00e-109	390.00
IUUC-Cel-018703	Caenorhabditis elegans	27.92	5.00e-72	266.00
IUUC-Cja-019270	Callithrix jacchus	87.44	0.00e+00	1463.00
IUUC-Cfa-021262	Canis familiaris	87.77	0.00e+00	1458.00
IUUC-Cpo-021449	Cavia porcellus	82.85	0.00e+00	1341.00
IUUC-Csa-024140	Chlorocebus sabaeus	87.94	0.00e+00	1469.00
IUUC-Cho-024923	Choloepus hoffmanni	84.42	0.00e+00	691.00
IUUC-Cin-025373	Ciona intestinalis	39.63	2.00e-170	592.00
IUUC-Csv-026324	Ciona savignyi	41.43	0.00e+00	636.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	30.58	3.00e-80	293.00
IUUC-Cne-026998	Cryptococcus neoformans	30.91	3.00e-88	319.00
IUUC-Cme-027154	Cyanidioschyzon merolae	30.49	3.00e-58	219.00
IUUC-Dre-028674	Danio rerio	66.46	0.00e+00	1098.00
IUUC-Dno-028966	Dasypus novemcinctus	87.69	0.00e+00	1470.00
IUUC-Dor-030343	Dipodomys ordii	78.66	0.00e+00	819.00
IUUC-Dse-031385	Dothistroma septosporum	30.87	6.00e-84	305.00
IUUC-Dme-032044	Drosophila melanogaster	36.73	4.00e-129	455.00
IUUC-Ete-032506	Echinops telfairi	78.90	0.00e+00	766.00
IUUC-Eca-033547	Equus caballus	88.08	0.00e+00	1469.00
IUUC-Eeu-034462	Erinaceus europaeus	73.73	0.00e+00	630.00
IUUC-Fca-035893	Felis catus	88.96	0.00e+00	1481.00
IUUC-Fal-037235	Ficedula albicollis	82.41	0.00e+00	1383.00
IUUC-Fox-037836	Fusarium oxysporum	31.23	3.00e-93	336.00
IUUC-Fso-038251	Fusarium solani	30.71	1.00e-91	330.00
IUUC-Gmo-038648	Gadus morhua	66.32	0.00e+00	962.00
IUUC-Ggr-039867	Gaeumannomyces graminis	30.31	4.00e-83	302.00
IUUC-Gga-040989	Gallus gallus	81.16	0.00e+00	1357.00
IUUC-Gac-041344	Gasterosteus aculeatus	67.54	0.00e+00	1077.00
IUUC-Gma-043067	Glycine max	31.76	1.00e-103	370.00
IUUC-Ggo-045009	Gorilla gorilla	86.39	0.00e+00	1103.00
IUUC-Hsa-046807	Homo sapiens	87.69	0.00e+00	1466.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	87.81	0.00e+00	1471.00
IUUC-Kpa-049134	Komagataella pastoris	43.20	6.00e-87	315.00
IUUC-Lch-049597	Latimeria chalumnae	74.05	0.00e+00	750.00
IUUC-Lpe-050821	Leersia perrieri	32.07	3.00e-99	356.00
IUUC-Loc-051849	Lepisosteus oculatus	73.33	0.00e+00	1216.00
IUUC-Lma-053297	Leptosphaeria maculans	33.98	2.00e-102	367.00
IUUC-Laf-053495	Loxodonta africana	88.50	0.00e+00	1471.00
IUUC-Meu-055983	Macropus eugenii	88.66	0.00e+00	705.00
IUUC-Mor-057006	Magnaporthe oryzae	36.44	1.00e-73	271.00
IUUC-Mpo-057465	Magnaporthe poae	36.40	7.00e-73	268.00
IUUC-Mtr-058374	Medicago truncatula	33.17	3.00e-112	399.00
IUUC-Mla-058895	Melampsora laricipopulina	35.61	5.00e-78	284.00
IUUC-Mvi-060297	Microbotryum violaceum	34.92	9.00e-109	387.00
IUUC-Mmr-060810	Microcebus murinus	82.50	0.00e+00	1347.00
IUUC-Mmu-063536	Mus musculus	87.19	0.00e+00	1428.00
IUUC-Mac-064902	Musa acuminata	32.46	6.00e-101	362.00
IUUC-Mpu-066085	Mustela putorius furo	88.58	0.00e+00	1477.00
IUUC-Mlu-067907	Myotis lucifugus	86.23	0.00e+00	934.00
IUUC-Nfi-068457	Neosartorya fischeri	32.11	7.00e-71	261.00
IUUC-Ncr-068622	Neurospora crassa	29.82	4.00e-90	326.00
IUUC-Nle-069049	Nomascus leucogenys	86.81	0.00e+00	1437.00
IUUC-Opr-071013	Ochotona princeps	68.15	1.00e-173	603.00
IUUC-Ont-071339	Oreochromis niloticus	69.10	0.00e+00	1145.00
IUUC-Oan-073353	Ornithorhynchus anatinus	84.68	8.00e-114	402.00
IUUC-Ocu-074625	Oryctolagus cuniculus	88.19	0.00e+00	1475.00
IUUC-Oba-075226	Oryza barthii	29.20	1.00e-85	311.00
IUUC-Obr-076875	Oryza brachyantha	33.08	3.00e-110	392.00
IUUC-Ogl-077057	Oryza glaberrima	32.46	3.00e-110	392.00
IUUC-Ogu-078156	Oryza glumaepatula	32.29	4.00e-110	392.00
IUUC-Oin-079373	Oryza indica	32.08	6.00e-109	388.00
IUUC-Olo-080849	Oryza longistaminata	29.48	5.00e-76	278.00
IUUC-Ome-081654	Oryza meridionalis	28.77	2.00e-85	310.00
IUUC-Oni-082221	Oryza nivara	28.89	3.00e-87	316.00
IUUC-Opu-084103	Oryza punctata	29.26	6.00e-86	311.00
IUUC-Oru-084751	Oryza rufipogon	28.54	1.00e-84	307.00
IUUC-Osa-085584	Oryza sativa	32.17	1.00e-108	387.00
IUUC-Ola-086974	Oryzias latipes	68.68	0.00e+00	1154.00
IUUC-Oga-088052	Otolemur garnettii	83.31	0.00e+00	1370.00
IUUC-Oar-089509	Ovis aries	87.44	0.00e+00	1449.00
IUUC-Ptr-090911	Pan troglodytes	87.81	0.00e+00	1469.00
IUUC-Pan-092141	Papio anubis	87.48	0.00e+00	1459.00
IUUC-Psi-093543	Pelodiscus sinensis	82.81	0.00e+00	1294.00
IUUC-Pno-094952	Phaeosphaeria nodorum	32.94	3.00e-96	346.00
IUUC-Ppa-095881	Physcomitrella patens	32.35	1.00e-110	394.00
IUUC-Pfo-096739	Poecilia formosa	67.46	0.00e+00	1121.00
IUUC-Pab-098641	Pongo abelii	87.81	0.00e+00	1468.00
IUUC-Pop-099621	Populus trichocarpa	31.96	2.00e-105	377.00
IUUC-Pca-100599	Procavia capensis	80.72	0.00e+00	1238.00
IUUC-Ppe-101874	Prunus persica	32.16	5.00e-107	382.00
IUUC-Pva-103009	Pteropus vampyrus	84.60	0.00e+00	1189.00
IUUC-Pgr-103260	Puccinia graminis	33.04	3.00e-95	343.00
IUUC-Ptt-103711	Puccinia triticina	31.70	2.00e-88	320.00
IUUC-Pte-104337	Pyrenophora teres	32.99	2.00e-91	330.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	33.38	2.00e-93	336.00
IUUC-Rno-105273	Rattus norvegicus	87.06	0.00e+00	1459.00
IUUC-Sce-106351	Saccharomyces cerevisiae	39.12	2.00e-80	293.00
IUUC-Sha-106758	Sarcophilus harrisii	95.99	0.00e+00	1569.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	38.99	1.00e-91	331.00
IUUC-Spo-108093	Schizosaccharomyces pombe	34.17	1.00e-98	354.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	30.55	1.00e-89	324.00
IUUC-Smo-109368	Selaginella moellendorffii	30.60	6.00e-97	348.00
IUUC-Sit-109699	Setaria italica	34.02	3.00e-109	389.00
IUUC-Sly-111063	Solanum lycopersicum	32.55	1.00e-102	367.00
IUUC-Sar-113199	Sorex araneus	91.98	0.00e+00	788.00
IUUC-Sbi-114745	Sorghum bicolor	32.63	9.00e-101	361.00
IUUC-Sre-115080	Sporisorium reilianum	39.84	8.00e-99	355.00
IUUC-Ssc-115666	Sus scrofa	87.39	0.00e+00	1453.00
IUUC-Tgu-116877	Taeniopygia guttata	81.41	0.00e+00	1373.00
IUUC-Tru-117580	Takifugu rubripes	67.68	0.00e+00	1140.00
IUUC-Tsy-118946	Tarsius syrichta	88.07	0.00e+00	1360.00
IUUC-Tni-119755	Tetraodon nigroviridis	64.30	0.00e+00	1055.00
IUUC-Tca-120977	Theobroma cacao	30.80	5.00e-100	358.00
IUUC-Tre-122217	Trichoderma reesei	32.74	1.00e-98	353.00
IUUC-Tvi-122671	Trichoderma virens	31.21	2.00e-93	336.00
IUUC-Tae-125581	Triticum aestivum	32.74	6.00e-105	375.00
IUUC-Tur-126404	Triticum urartu	24.02	4.00e-21	96.70
IUUC-Tme-126971	Tuber melanosporum	33.72	1.00e-111	397.00
IUUC-Tbe-127858	Tupaia belangeri	69.28	5.00e-171	594.00
IUUC-Ttr-128173	Tursiops truncatus	86.83	0.00e+00	1425.00
IUUC-Uma-129322	Ustilago maydis	33.46	6.00e-104	372.00
IUUC-Vda-129682	Verticillium dahliae	30.72	1.00e-86	314.00
IUUC-Vpa-130607	Vicugna pacos	86.61	0.00e+00	1330.00
IUUC-Vvi-131153	Vitis vinifera	33.33	4.00e-111	395.00
IUUC-Xtr-132208	Xenopus tropicalis	75.19	0.00e+00	1253.00
IUUC-Xma-133098	Xiphophorus maculatus	68.58	0.00e+00	1122.00
IUUC-Yli-134646	Yarrowia lipolytica	38.59	5.00e-95	342.00
IUUC-Zma-135920	Zea mays	30.88	9.00e-90	324.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence