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Tag Content
iUUCD ID IUUC-Lch-049868
Ensembl Protein ID ENSLACP00000022176.1
UniProt Accession M3XHH0; M3XHH0_LATCH
Genbank Protein ID ENSLACP00000022176
Protein Name Tyrosine-protein kinase
Genbank Nucleotide ID AFYH01037441
Gene Name BTK
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSLACG00000017180.2 ENSLACT00000026314.1 ENSLACP00000022176.1
ENSLACG00000017180.2 ENSLACT00000019675.1 ENSLACP00000019537.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.10e-10 41.5 174 230
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +++ +lydy++ +  ++ l kG+  +vi  ee ++ W+k+ ++ +g++G +P+n+v+++
   Q: 174  TKVIVALYDYKPMEALDMPLVKGEEYYVI--EEANAQWWKA-RDKNGQEGYIPSNYVTEA 230
           567889***********************..999*******.5**************987 PP
   
Organism Latimeria chalumnae
Protein Sequence
(Fasta)
MNMTLNEGKK GSKKGSVDVD KISCVETVAP EENPPPERQI LRKGDDMVEM EQISVIERFP 60
YPFQIIYDEG PLYIFAPTEE LRQRWIKELK NVTRFNKDLA QKYHPCFWID GEWLCCKQIA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Lch-049868|UBD,SH3|Latimeria chalumnae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCAGCTGGGC TCAGAACTGT AGCAGAAGCA ATGTCGAGTG TCATTTTAGA GAGTATCTTC 60
CTTAAGAGGT CCCAACAGAA GAAAAAGACT TCCCCCCTGA ACTTTAAAAA GAGGCTTTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Lch-049868|UBD,SH3|Latimeria chalumnae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR001562--Znf_Btk_motif
PROSITE

PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
PS51113--ZF_BTK
Pfam

PF00779--BTK
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE
SMART

SM00107--BTK
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005622--C:intracellular
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0035556--P:intracellular signal transduction
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001365 Ailuropoda melanoleuca 75.45 0.00e+00 972.00
IUUC-Apl-003907 Anas platyrhynchos 74.26 0.00e+00 942.00
IUUC-Aca-004978 Anolis carolinensis 72.22 0.00e+00 920.00
IUUC-Bta-012467 Bos taurus 75.29 0.00e+00 971.00
IUUC-Cja-018841 Callithrix jacchus 74.59 0.00e+00 964.00
IUUC-Cfa-020983 Canis familiaris 75.12 0.00e+00 962.00
IUUC-Cpo-021307 Cavia porcellus 74.76 0.00e+00 969.00
IUUC-Csa-023508 Chlorocebus sabaeus 74.75 0.00e+00 782.00
IUUC-Dno-029828 Dasypus novemcinctus 74.14 0.00e+00 947.00
IUUC-Dor-030102 Dipodomys ordii 69.02 0.00e+00 846.00
IUUC-Ete-032981 Echinops telfairi 67.81 0.00e+00 847.00
IUUC-Eca-033594 Equus caballus 75.29 0.00e+00 970.00
IUUC-Eeu-035281 Erinaceus europaeus 71.03 0.00e+00 741.00
IUUC-Fca-035495 Felis catus 74.96 0.00e+00 960.00
IUUC-Fal-036719 Ficedula albicollis 75.41 0.00e+00 976.00
IUUC-Gga-041193 Gallus gallus 74.06 0.00e+00 941.00
IUUC-Gma-043813 Glycine max 31.22 4.00e-18 86.30
IUUC-Hsa-045931 Homo sapiens 74.63 0.00e+00 959.00
IUUC-Itr-048061 Ictidomys tridecemlineatus 75.78 0.00e+00 975.00
IUUC-Laf-053516 Loxodonta africana 74.71 0.00e+00 984.00
IUUC-Mcc-054795 Macaca mulatta 74.27 0.00e+00 960.00
IUUC-Meu-056157 Macropus eugenii 65.63 0.00e+00 819.00
IUUC-Mga-059529 Meleagris gallopavo 74.77 0.00e+00 863.00
IUUC-Mmr-060824 Microcebus murinus 74.40 0.00e+00 907.00
IUUC-Mdo-063036 Monodelphis domestica 75.97 0.00e+00 958.00
IUUC-Mmu-064047 Mus musculus 75.45 0.00e+00 971.00
IUUC-Mpu-066810 Mustela putorius furo 75.78 0.00e+00 975.00
IUUC-Mlu-067671 Myotis lucifugus 74.47 0.00e+00 962.00
IUUC-Nle-069108 Nomascus leucogenys 74.63 0.00e+00 961.00
IUUC-Opr-070505 Ochotona princeps 59.47 1.00e-156 546.00
IUUC-Oan-073495 Ornithorhynchus anatinus 74.35 0.00e+00 990.00
IUUC-Ocu-074416 Oryctolagus cuniculus 74.59 0.00e+00 971.00
IUUC-Oga-088995 Otolemur garnettii 74.23 0.00e+00 959.00
IUUC-Oar-089632 Ovis aries 73.98 0.00e+00 954.00
IUUC-Ptr-090941 Pan troglodytes 74.63 0.00e+00 960.00
IUUC-Pan-091900 Papio anubis 71.99 0.00e+00 923.00
IUUC-Psi-093048 Pelodiscus sinensis 73.17 0.00e+00 912.00
IUUC-Pab-097587 Pongo abelii 74.80 0.00e+00 961.00
IUUC-Pca-100374 Procavia capensis 63.09 8.00e-112 397.00
IUUC-Pva-102583 Pteropus vampyrus 75.12 0.00e+00 948.00
IUUC-Rno-104868 Rattus norvegicus 71.94 0.00e+00 908.00
IUUC-Sha-106744 Sarcophilus harrisii 75.45 0.00e+00 986.00
IUUC-Sar-113041 Sorex araneus 75.21 0.00e+00 919.00
IUUC-Ssc-115294 Sus scrofa 75.08 0.00e+00 971.00
IUUC-Tsy-118945 Tarsius syrichta 77.18 0.00e+00 713.00
IUUC-Ttr-128769 Tursiops truncatus 67.43 0.00e+00 853.00
Created Date 25-Jun-2017

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