iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066307

Ensembl Protein ID

ENSMPUP00000007703.1

UniProt Accession

M3Y8P6; M3Y8P6_MUSPF

Genbank Protein ID

ENSMPUP00000007703

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01050783

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007759.1	ENSMPUT00000007826.1	ENSMPUP00000007703.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-78	264.9	2	595

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 17   QcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqlee 105
           QcLsn+  l+e+l     ++ +        +e++++l+ l+++lw+++ +     e+++a++k+ ++f+ + q+Da Efl +lld+++e
   Q: 2    QCLSNTDLLAEFLALGRYRAAPG------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQDNGQHDALEFLLWLLDRVHE 84
           9***********99955555555......479********************************************************* PP
   S: 106  elkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke....... 185
           +l+ +++ p  e+ + + s+++++  +++ +++  +s+++  Fq q++s+++c++c ++s++++pfl +slp+p ++++ ++       
   Q: 85   DLEGSSRGPGAEKPQPEASRSPENlpSPSAQPSPVPSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSvtlvfps 173
           **9988899999888888888888778889999999*****************************************98888******* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 174  ksqrflrvglavpilstvaalrkmvaeeggvpadevilvelcpsgfqrsffdeedlntisegdnvyafhapppsgqellsahpsglavs 262
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 263  prlaardglrsslpihsenkvlvlfcnlvgsgqqasrfgppfllredraiswlqlqqcilskvrcvmkseapiqnpgslfsvrvvglsl 351
           ***************************************************************************************** PP
   S: 186  ..........................................................................slqdcLesftkeeel 200
                                                                                     +l++c++ +tkee+l
   Q: 352  gcgylspqdshplchwavdralhlrrpggpphvklavewdsctkerlfgslqeervqdadsvwrqqqahqqhscTLDECFQFYTKEEQL 440
           ***************************************************************************************** PP
   S: 201  egenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke.............. 274
            ++++++c++c+++q+   kl+l++lP++Li+hLkRf   + +++r+k+++ v+fpl+ L+++p+++++ ++                 
   Q: 441  AQDDAWKCPHCQALQQGMVKLSLWTLPDILIIHLKRF--CQVGERRNKLSTLVQFPLSgLNMAPHVAQRGTGPPPgtgswppwkqpagl 527
           *************************************..88899************************666655588888888889999 PP
   S: 275  ......kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
                 +  Y+L+av++H+Gsl++GHY+ay++n  +g+W+ +dDs+V++++e+ev++   + aY+lfY++r
   Q: 528  pagyplDFLYDLYAVCNHHGSLQGGHYTAYCRNsLDGQWYSYDDSTVESLPEDEVNS---RGAYILFYQKR 595
           999999***************************55788*******************...********985 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

XQCLSNTDLL AEFLALGRYR AAPGRAEVTE QLAALVRALW TREYTPQLSA EFKNAVSKYG 60
SQFQDNGQHD ALEFLLWLLD RVHEDLEGSS RGPGAEKPQP EASRSPENLP SPSAQPSPVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NTGCAGTGTC TCAGCAACAC CGACCTGCTG GCCGAGTTCC TGGCGCTGGG GCGCTACCGG 60
GCGGCGCCGG GCCGCGCCGA GGTCACCGAG CAGCTGGCGG CGCTGGTGCG CGCGCTCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	86.01	0.00e+00	1605.00
IUUC-Aca-004436	Anolis carolinensis	52.84	0.00e+00	780.00
IUUC-Ame-011153	Astyanax mexicanus	47.11	0.00e+00	819.00
IUUC-Bta-013560	Bos taurus	78.33	0.00e+00	1510.00
IUUC-Cja-018737	Callithrix jacchus	76.37	0.00e+00	1452.00
IUUC-Cfa-020347	Canis familiaris	82.83	0.00e+00	1596.00
IUUC-Csa-023656	Chlorocebus sabaeus	78.25	0.00e+00	1477.00
IUUC-Cho-024864	Choloepus hoffmanni	68.37	0.00e+00	838.00
IUUC-Csv-026086	Ciona savignyi	38.59	3.00e-121	429.00
IUUC-Dre-028066	Danio rerio	47.34	0.00e+00	839.00
IUUC-Dno-028855	Dasypus novemcinctus	70.77	0.00e+00	1254.00
IUUC-Dor-030475	Dipodomys ordii	84.48	0.00e+00	706.00
IUUC-Dme-032088	Drosophila melanogaster	35.62	3.00e-100	360.00
IUUC-Eca-034147	Equus caballus	82.75	0.00e+00	1349.00
IUUC-Eeu-034703	Erinaceus europaeus	82.68	6.00e-121	428.00
IUUC-Fca-036550	Felis catus	76.60	0.00e+00	1326.00
IUUC-Gmo-038903	Gadus morhua	49.09	3.00e-176	612.00
IUUC-Gac-042087	Gasterosteus aculeatus	48.37	0.00e+00	809.00
IUUC-Ggo-045171	Gorilla gorilla	78.45	0.00e+00	1478.00
IUUC-Hsa-045961	Homo sapiens	78.45	0.00e+00	1481.00
IUUC-Loc-052852	Lepisosteus oculatus	60.18	0.00e+00	856.00
IUUC-Laf-054033	Loxodonta africana	73.95	0.00e+00	1374.00
IUUC-Mcc-055431	Macaca mulatta	78.15	0.00e+00	1479.00
IUUC-Mmr-061035	Microcebus murinus	79.92	0.00e+00	1482.00
IUUC-Mdo-062172	Monodelphis domestica	65.19	0.00e+00	895.00
IUUC-Mmu-063966	Mus musculus	72.27	0.00e+00	1381.00
IUUC-Nle-070172	Nomascus leucogenys	77.95	0.00e+00	1475.00
IUUC-Opr-070499	Ochotona princeps	70.12	0.00e+00	1281.00
IUUC-Ont-071920	Oreochromis niloticus	48.60	0.00e+00	837.00
IUUC-Ocu-074014	Oryctolagus cuniculus	78.35	0.00e+00	1162.00
IUUC-Ola-086360	Oryzias latipes	49.56	0.00e+00	839.00
IUUC-Oga-088202	Otolemur garnettii	77.14	0.00e+00	1445.00
IUUC-Oar-089819	Ovis aries	76.79	0.00e+00	1479.00
IUUC-Ptr-091076	Pan troglodytes	78.35	0.00e+00	1481.00
IUUC-Pan-092248	Papio anubis	78.05	0.00e+00	1471.00
IUUC-Pfo-096534	Poecilia formosa	57.16	0.00e+00	751.00
IUUC-Pab-098453	Pongo abelii	77.93	0.00e+00	1464.00
IUUC-Pca-100290	Procavia capensis	58.06	0.00e+00	655.00
IUUC-Pva-102317	Pteropus vampyrus	71.43	0.00e+00	1312.00
IUUC-Rno-104948	Rattus norvegicus	71.88	0.00e+00	1301.00
IUUC-Sha-106558	Sarcophilus harrisii	56.55	0.00e+00	1059.00
IUUC-Sar-113105	Sorex araneus	59.27	0.00e+00	962.00
IUUC-Ssc-115312	Sus scrofa	78.15	0.00e+00	1474.00
IUUC-Tru-117995	Takifugu rubripes	59.01	0.00e+00	830.00
IUUC-Tsy-119325	Tarsius syrichta	71.03	0.00e+00	695.00
IUUC-Tni-120517	Tetraodon nigroviridis	54.96	0.00e+00	790.00
IUUC-Tbe-127439	Tupaia belangeri	63.90	2.00e-118	420.00
IUUC-Ttr-128829	Tursiops truncatus	70.79	0.00e+00	1313.00
IUUC-Vpa-130306	Vicugna pacos	77.09	4.00e-160	559.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence