iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-33	113.3	460	491
UBD/Beta-Prp	2.80e-59	201.1	504	614

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlr 31
           H++sv+c++   ++   v++s Dgt+ +WDl 
   Q: 460  HKSSVSCIRVkkNNEECVTASTDGTCIIWDLV 491
           9**********87799**************85 PP

UBD/Beta-Prp

   S: 139  vvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvks 227
           + +cv++hp+++ ++++++Dr++  W +  g+++r+l+g   +sv+ ++++++g+++v+g++d  +k+wd+ +ge+ +   gh+ n+  
   Q: 504  LFQCVCYHPEEFQIITSGTDRKIAYWEVFDGSVIRELEGSLSGSVNGMDITQEGEHFVTGGHDHLIKVWDYNEGEVTHVGVGHSGNIMG 592
           578************************************************************************************** PP
   S: 228  vrfspnderlvsgssDgsiriW 249
           +r sp ++++vs+s+Dg i  W
   Q: 593  IRISPGNQYIVSVSADGAILRW 614
           *******************999 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEEQILPETD VAELELQAVI GFNGHVPNGL KCHPDQEHLV YPLGCTVLIQ AINTNEQNFL 60
HGHGNNVSCV TISKEGDYVA SGQVTFMGFK ADIILWDFKK RELIARLSLH KGKIEALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAACGACTA GGAGACGCTG CACCCTGGAG TTGAGGAATC AACCAGCTGA AACTCTCCAG 60
GATGGAAGAA CAAATTTTAC CCGAGACCGA CGTAGCCGAA CTGGAGCTTC AGGCTGTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR033015--CFAP52
IPR023302--Pept_S9A_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

KEGG

rno:303233

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002048	Ailuropoda melanoleuca	91.77	0.00e+00	1175.00
IUUC-Apl-004011	Anas platyrhynchos	70.81	0.00e+00	904.00
IUUC-Aca-004805	Anolis carolinensis	73.17	0.00e+00	956.00
IUUC-Ame-010655	Astyanax mexicanus	62.15	0.00e+00	798.00
IUUC-Bta-013493	Bos taurus	91.85	0.00e+00	1140.00
IUUC-Cja-019923	Callithrix jacchus	90.97	0.00e+00	1168.00
IUUC-Cfa-020609	Canis familiaris	92.10	0.00e+00	1164.00
IUUC-Cpo-022158	Cavia porcellus	91.68	0.00e+00	1147.00
IUUC-Cre-022705	Chlamydomonas reinhardtii	45.56	8.00e-162	563.00
IUUC-Csa-023338	Chlorocebus sabaeus	91.45	0.00e+00	1176.00
IUUC-Cho-024884	Choloepus hoffmanni	85.05	0.00e+00	717.00
IUUC-Cin-025634	Ciona intestinalis	62.40	0.00e+00	807.00
IUUC-Csv-026211	Ciona savignyi	65.31	4.00e-96	343.00
IUUC-Dre-028268	Danio rerio	64.47	0.00e+00	872.00
IUUC-Dno-029202	Dasypus novemcinctus	86.02	0.00e+00	1046.00
IUUC-Dor-030197	Dipodomys ordii	80.73	0.00e+00	761.00
IUUC-Dme-032037	Drosophila melanogaster	35.96	5.00e-114	405.00
IUUC-Ete-033049	Echinops telfairi	81.88	0.00e+00	981.00
IUUC-Eca-033884	Equus caballus	92.26	0.00e+00	1155.00
IUUC-Eeu-034477	Erinaceus europaeus	80.38	2.00e-179	622.00
IUUC-Fca-035453	Felis catus	89.46	0.00e+00	1136.00
IUUC-Gmo-039448	Gadus morhua	64.75	2.00e-111	396.00
IUUC-Gga-040295	Gallus gallus	71.41	0.00e+00	942.00
IUUC-Gac-042074	Gasterosteus aculeatus	56.39	0.00e+00	705.00
IUUC-Ggo-044438	Gorilla gorilla	91.74	0.00e+00	909.00
IUUC-Hsa-046794	Homo sapiens	90.65	0.00e+00	1165.00
IUUC-Itr-048315	Ictidomys tridecemlineatus	94.81	0.00e+00	698.00
IUUC-Lch-050554	Latimeria chalumnae	67.07	0.00e+00	815.00
IUUC-Loc-052080	Lepisosteus oculatus	69.08	0.00e+00	903.00
IUUC-Laf-054288	Loxodonta africana	91.45	0.00e+00	1149.00
IUUC-Mcc-055746	Macaca mulatta	84.52	0.00e+00	1058.00
IUUC-Meu-056507	Macropus eugenii	74.03	7.00e-147	514.00
IUUC-Mga-059858	Meleagris gallopavo	71.24	0.00e+00	895.00
IUUC-Mmr-061757	Microcebus murinus	91.62	0.00e+00	1021.00
IUUC-Mdo-062670	Monodelphis domestica	82.28	0.00e+00	1084.00
IUUC-Mmu-064084	Mus musculus	97.58	0.00e+00	1241.00
IUUC-Mpu-066253	Mustela putorius furo	91.45	0.00e+00	1148.00
IUUC-Mlu-067944	Myotis lucifugus	76.03	0.00e+00	902.00
IUUC-Nle-069098	Nomascus leucogenys	91.13	0.00e+00	1168.00
IUUC-Opr-070525	Ochotona princeps	83.64	0.00e+00	913.00
IUUC-Ont-071609	Oreochromis niloticus	58.08	0.00e+00	765.00
IUUC-Oan-073543	Ornithorhynchus anatinus	77.38	0.00e+00	996.00
IUUC-Ocu-074209	Oryctolagus cuniculus	90.65	0.00e+00	1172.00
IUUC-Ola-086464	Oryzias latipes	55.92	0.00e+00	732.00
IUUC-Olu-087600	Ostreococcus lucimarinus	33.03	6.00e-94	338.00
IUUC-Oga-088977	Otolemur garnettii	91.13	0.00e+00	1170.00
IUUC-Oar-089192	Ovis aries	91.68	0.00e+00	1139.00
IUUC-Ptr-090882	Pan troglodytes	86.10	0.00e+00	1077.00
IUUC-Pan-092865	Papio anubis	86.98	0.00e+00	1106.00
IUUC-Psi-093270	Pelodiscus sinensis	75.80	0.00e+00	852.00
IUUC-Pma-094291	Petromyzon marinus	63.30	0.00e+00	854.00
IUUC-Ppa-095984	Physcomitrella patens	42.36	3.00e-147	515.00
IUUC-Pfo-097344	Poecilia formosa	50.74	0.00e+00	676.00
IUUC-Pab-098278	Pongo abelii	91.13	0.00e+00	1169.00
IUUC-Pca-101037	Procavia capensis	92.28	0.00e+00	1144.00
IUUC-Pva-102351	Pteropus vampyrus	91.91	0.00e+00	964.00
IUUC-Smo-109009	Selaginella moellendorffii	43.84	8.00e-162	563.00
IUUC-Sar-113156	Sorex araneus	78.55	2.00e-140	492.00
IUUC-Ssc-116319	Sus scrofa	90.24	4.00e-64	236.00
IUUC-Tru-117963	Takifugu rubripes	55.65	0.00e+00	723.00
IUUC-Tsy-119115	Tarsius syrichta	72.15	0.00e+00	820.00
IUUC-Tni-120388	Tetraodon nigroviridis	54.16	0.00e+00	687.00
IUUC-Tbe-127930	Tupaia belangeri	82.07	0.00e+00	630.00
IUUC-Ttr-128981	Tursiops truncatus	90.77	0.00e+00	1094.00
IUUC-Vpa-130492	Vicugna pacos	83.56	0.00e+00	1043.00
IUUC-Xtr-132142	Xenopus tropicalis	69.14	0.00e+00	918.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence