iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013232

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02075759

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000005219.3	ENSBTAT00000006877.3	ENSBTAP00000006877.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.40e-17	62.1	181	248
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.20e-07	31.0	280	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+l+ g  +++ah++vL+a S++F a+f+++  e k +++v++++++p +++ l+++ Ytg l+++e
   Q: 181  CDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAK-QKEVKMEGIDPNALNSLVQYAYTGILQLKE 248
           8************************************9.*************************99986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgil+f+d+ +c++L  +a +++  hF
   Q: 280  PSNCLGILSFGDAQGCTKLLNVAYRYTMEHF 310
           89************************98777 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPSQGSP NTGNCLQQEG YEHRETPVQG RLKNHSWDRN 60
GLKKSNSPVH HSILLPEPEL APAHQRALQN WHSGKLIEHL RANEDTPKAV SWNLFKEAYK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAACAAGA AAGACTGCTC TCGACACTTC TGCTTTTGTT AGTCCTACAG AAGAGGCAGA 60
GAAACAAGAG ATAACAAAGG CTGTTTCCTT TCTGTGAGAG AAGGCTTTCG TCTTTCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	89.25	0.00e+00	1152.00
IUUC-Aca-004238	Anolis carolinensis	76.59	0.00e+00	967.00
IUUC-Ame-011287	Astyanax mexicanus	68.93	0.00e+00	883.00
IUUC-Cja-018916	Callithrix jacchus	88.47	0.00e+00	1142.00
IUUC-Cfa-020972	Canis familiaris	92.42	0.00e+00	932.00
IUUC-Csa-023849	Chlorocebus sabaeus	89.10	0.00e+00	1149.00
IUUC-Dre-028417	Danio rerio	73.63	0.00e+00	805.00
IUUC-Dor-030708	Dipodomys ordii	82.87	0.00e+00	1072.00
IUUC-Ete-033156	Echinops telfairi	80.04	0.00e+00	800.00
IUUC-Eca-033542	Equus caballus	89.41	0.00e+00	1156.00
IUUC-Fal-036999	Ficedula albicollis	78.07	0.00e+00	997.00
IUUC-Fox-038050	Fusarium oxysporum	29.11	1.00e-07	50.10
IUUC-Gga-040215	Gallus gallus	79.50	0.00e+00	1031.00
IUUC-Ggo-045074	Gorilla gorilla	89.72	0.00e+00	1162.00
IUUC-Hsa-046486	Homo sapiens	89.88	0.00e+00	1164.00
IUUC-Laf-053627	Loxodonta africana	88.47	0.00e+00	1139.00
IUUC-Mcc-055418	Macaca mulatta	89.56	0.00e+00	1156.00
IUUC-Meu-056859	Macropus eugenii	71.78	2.00e-138	485.00
IUUC-Mga-059582	Meleagris gallopavo	79.04	0.00e+00	963.00
IUUC-Mmr-061648	Microcebus murinus	89.72	0.00e+00	1162.00
IUUC-Mmu-063807	Mus musculus	83.64	0.00e+00	1080.00
IUUC-Mpu-066279	Mustela putorius furo	90.02	0.00e+00	912.00
IUUC-Mlu-067981	Myotis lucifugus	87.38	0.00e+00	1135.00
IUUC-Nle-070033	Nomascus leucogenys	89.10	0.00e+00	1153.00
IUUC-Ocu-073854	Oryctolagus cuniculus	90.43	0.00e+00	1063.00
IUUC-Oar-089952	Ovis aries	97.19	0.00e+00	1259.00
IUUC-Ptr-091649	Pan troglodytes	82.66	0.00e+00	1003.00
IUUC-Pan-091798	Papio anubis	89.41	0.00e+00	1155.00
IUUC-Psi-093728	Pelodiscus sinensis	77.64	0.00e+00	1008.00
IUUC-Pab-098461	Pongo abelii	88.63	0.00e+00	1142.00
IUUC-Pva-102458	Pteropus vampyrus	89.41	0.00e+00	1162.00
IUUC-Rno-105865	Rattus norvegicus	84.27	0.00e+00	1078.00
IUUC-Ssc-116001	Sus scrofa	91.90	0.00e+00	1191.00
IUUC-Tgu-116994	Taeniopygia guttata	79.16	0.00e+00	1010.00
IUUC-Tbe-128118	Tupaia belangeri	72.70	0.00e+00	920.00
IUUC-Ttr-129220	Tursiops truncatus	82.87	0.00e+00	1064.00
IUUC-Vpa-130811	Vicugna pacos	85.51	0.00e+00	1088.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence