iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004956

Ensembl Protein ID

ENSACAP00000003886.2

UniProt Accession

H9G8C2; H9G8C2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003900.3	ENSACAT00000029609.1	ENSACAP00000022192.1
ENSACAG00000003900.3	ENSACAT00000003978.2	ENSACAP00000003886.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.10e-35	117.5	640	676
UBD/Beta-Prp	6.00e-64	216.0	63	270

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           gHt+++t+l++   +d++lvs ++Dgt +vWD+ +  
   Q: 640  GHTAKITSLSWsphHDGRLVSVCYDGTAQVWDVLKEE 676
           8***********87669***************96665 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcle 130
            +l gh++ v+  +f p  +   + +++s+D+++k+wd  +   ++  + h++++ +l++sp  +d +vsG++  ++ ++ ++++  ++
   Q: 63   GELVGHTERVSGFSFCPCPDqnyLCASSSDDGAVKIWDTHSLAVLIEHSLHQNTISTLHWSPkVKDLIVSGDEKGIVICY-WHNRNDSQ 150
           6788999999988886543334677888888*******************************556**************8.88888888 PP
   S: 131  etlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls................fdsng......... 192
            t+ ++ +++ c++ +p   nl++ G +D++v + d+ + g+++++l+g h+d ++sl                 f+++          
   Q: 151  -TFFPEPRTIFCLTCSPHHeNLVAIGYKDGIVVVIDIsRKGDVVHRLRG-HDDEIHSLVwcpvvgeeaicsqheeFQEEEitagrvsee 237
           .9999999999999999999*****************999********9.*********888888887776666644444889999999 PP
   S: 193  ......kelvsgsldgtvklwdlqtgecvrtln 219
                  +l+sgs+d+t+++w++ +g++++tl+
   Q: 238  aagtkgYCLASGSKDQTIRVWSCTRGRVIMTLK 270
           999999***********************9985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

AVAAERVLPA SPNWYCGRCS DASQDGRLFG FAARHTVCLL EARPAGPAFY GKQPGLPPGA 60
STGELVGHTE RVSGFSFCPC PDQNYLCASS SDDGAVKIWD THSLAVLIEH SLHQNTISTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGTCGCCG CGGAGAGAGT GCTGCCGGCC TCTCCCAACT GGTACTGCGG CCGGTGCAGC 60
GACGCCTCCC AGGACGGGCG CCTGTTCGGC TTCGCGGCTC GCCACACGGT ATGCCTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	61.96	0.00e+00	1810.00
IUUC-Apl-003586	Anas platyrhynchos	64.89	0.00e+00	1728.00
IUUC-Ame-010753	Astyanax mexicanus	63.67	0.00e+00	1020.00
IUUC-Bta-012315	Bos taurus	62.43	0.00e+00	1828.00
IUUC-Cja-019334	Callithrix jacchus	61.85	0.00e+00	1838.00
IUUC-Cfa-021254	Canis familiaris	62.38	0.00e+00	1858.00
IUUC-Cpo-021984	Cavia porcellus	60.32	0.00e+00	1713.00
IUUC-Csa-023650	Chlorocebus sabaeus	62.49	0.00e+00	1817.00
IUUC-Cho-024860	Choloepus hoffmanni	59.20	0.00e+00	1675.00
IUUC-Cin-025778	Ciona intestinalis	40.90	7.00e-158	551.00
IUUC-Csv-026313	Ciona savignyi	41.45	1.00e-163	569.00
IUUC-Dre-028096	Danio rerio	65.43	0.00e+00	1031.00
IUUC-Dno-029799	Dasypus novemcinctus	65.69	0.00e+00	1668.00
IUUC-Dor-030885	Dipodomys ordii	59.16	1.00e-129	457.00
IUUC-Ete-032918	Echinops telfairi	59.40	0.00e+00	1741.00
IUUC-Eca-034144	Equus caballus	61.85	0.00e+00	1796.00
IUUC-Eeu-034843	Erinaceus europaeus	58.21	0.00e+00	1319.00
IUUC-Fca-035948	Felis catus	62.12	0.00e+00	1803.00
IUUC-Fal-037303	Ficedula albicollis	65.94	0.00e+00	1939.00
IUUC-Gmo-039591	Gadus morhua	54.50	0.00e+00	838.00
IUUC-Gga-040570	Gallus gallus	63.85	0.00e+00	1711.00
IUUC-Gac-042646	Gasterosteus aculeatus	48.41	0.00e+00	1326.00
IUUC-Ggo-045605	Gorilla gorilla	60.13	0.00e+00	1360.00
IUUC-Hsa-046122	Homo sapiens	62.49	0.00e+00	1827.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	66.39	0.00e+00	1674.00
IUUC-Lch-050489	Latimeria chalumnae	55.90	0.00e+00	640.00
IUUC-Loc-052259	Lepisosteus oculatus	62.04	0.00e+00	974.00
IUUC-Laf-053338	Loxodonta africana	62.53	0.00e+00	1835.00
IUUC-Mcc-055442	Macaca mulatta	62.55	0.00e+00	1816.00
IUUC-Meu-056245	Macropus eugenii	72.48	0.00e+00	741.00
IUUC-Mga-060202	Meleagris gallopavo	64.49	0.00e+00	1807.00
IUUC-Mmr-061730	Microcebus murinus	61.26	0.00e+00	1793.00
IUUC-Mdo-062880	Monodelphis domestica	64.92	0.00e+00	1918.00
IUUC-Mmu-063930	Mus musculus	62.09	0.00e+00	1768.00
IUUC-Mpu-066605	Mustela putorius furo	62.25	0.00e+00	1828.00
IUUC-Mlu-067765	Myotis lucifugus	62.44	0.00e+00	1852.00
IUUC-Nle-069183	Nomascus leucogenys	61.92	0.00e+00	1773.00
IUUC-Opr-070659	Ochotona princeps	51.61	0.00e+00	735.00
IUUC-Ont-072356	Oreochromis niloticus	60.95	0.00e+00	984.00
IUUC-Oan-073056	Ornithorhynchus anatinus	64.77	0.00e+00	1844.00
IUUC-Ocu-073881	Oryctolagus cuniculus	62.64	0.00e+00	1865.00
IUUC-Ola-087120	Oryzias latipes	54.84	3.00e-65	240.00
IUUC-Olu-087648	Ostreococcus lucimarinus	24.45	4.00e-29	123.00
IUUC-Oga-088343	Otolemur garnettii	62.48	0.00e+00	1834.00
IUUC-Oar-089257	Ovis aries	61.88	0.00e+00	1837.00
IUUC-Ptr-090497	Pan troglodytes	62.16	0.00e+00	1807.00
IUUC-Pan-092638	Papio anubis	62.43	0.00e+00	1823.00
IUUC-Psi-093096	Pelodiscus sinensis	67.13	0.00e+00	1726.00
IUUC-Pma-094571	Petromyzon marinus	39.42	3.00e-77	282.00
IUUC-Pfo-096742	Poecilia formosa	47.81	0.00e+00	1339.00
IUUC-Pab-098153	Pongo abelii	62.48	0.00e+00	1838.00
IUUC-Pca-100957	Procavia capensis	59.48	0.00e+00	1713.00
IUUC-Pva-102439	Pteropus vampyrus	62.17	0.00e+00	1833.00
IUUC-Rno-105891	Rattus norvegicus	61.95	0.00e+00	1751.00
IUUC-Sha-107181	Sarcophilus harrisii	66.13	0.00e+00	1863.00
IUUC-Ssc-115413	Sus scrofa	62.13	0.00e+00	1867.00
IUUC-Tgu-117082	Taeniopygia guttata	66.26	0.00e+00	1910.00
IUUC-Tru-118491	Takifugu rubripes	58.61	0.00e+00	926.00
IUUC-Tsy-119629	Tarsius syrichta	70.93	2.00e-125	443.00
IUUC-Tni-120240	Tetraodon nigroviridis	59.05	0.00e+00	928.00
IUUC-Tbe-127673	Tupaia belangeri	54.49	0.00e+00	1469.00
IUUC-Ttr-128562	Tursiops truncatus	59.83	0.00e+00	1741.00
IUUC-Vpa-130596	Vicugna pacos	63.27	0.00e+00	1378.00
IUUC-Xtr-132469	Xenopus tropicalis	56.77	0.00e+00	1643.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence