iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040570

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000140

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000003937.5	ENSGALT00000006272.5	ENSGALP00000006262.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-32	109.6	465	502
UBD/Beta-Prp	5.70e-44	150.8	369	650

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt++vt+l++  +  ++lvs+++Dgt +vWD+ +  +
   Q: 465  GHTSKVTSLSWspHHeGRLVSACYDGTAQVWDVMKEEP 502
           8***********733699**************977665 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.......ilvtgseDrtikvwdls............tg 84
            + ++pd++lla g +dg+i+++++ + kll ++++h + ++a++++++         ++++gs  ++i+v +l+              
   Q: 369  EISWKPDGKLLALGNEDGSIEIFQAPNLKLLCTIQQHHKLINAIRWHHEHGsdpelsyLIASGSVNAIIYVHNLKsviestsespltIT 457
           46779*******************************************988899***9**************99999999999999889 PP
   S: 85   kcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl..... 166
           ++++tl gh+++v+sls+sp    +lvs+  d t++vwd+ +++ l    +gh+g   cv+++p + + + +G++D  v  W +     
   Q: 458  EPFRTLAGHTSKVTSLSWSPhHEGRLVSACYDGTAQVWDVMKEEPLC-NYRGHQGRLLCVQWSPVDsDSIYTGADDFSVHKWLIskqeh 545
           9*******************555***********************9.9*********************************9988888 PP
   S: 167  .........................ktgkllrtltgghtdsvyslsfdsng....................................ke 194
                                    k           ++++v     ++++                                    k+
   Q: 546  trppqgkksielekkrsiqpkvkakK-----------KKKPVGRSPAKQDQsdavngdesmkdtlleengvsdhegekeaqetelpdKD 623
           88866665555554444444443331...........2222222222222233444444444445555555555567777777777788 PP
   S: 195  lvsgsldgtvklwdlq...tgecvrtl 218
            +++s+d+++  +d++   +++  +t+
   Q: 624  SIAVSKDTSLSAYDYSslsSSKPFVTQ 650
           888999999999988866555555555 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MVVIIDISRK KEVLHRLRGH DDEIHCLAWC PVPGEGRLPA WQDELQEESD VPNGELKQDT 60
AMKKSCYLAS GSKDQTIRIW SCTRGRSVMT LKLPPTKRRG GAVDPAVKER IWLTVHWPCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGCAATCA CAGCGTTACA CTGGTCACCC CTTGTGAAAG ATTTGATTGT ATCCGGTGAT 60
GAAAAAGGGG TAATTGTTTG TTACTGGCAT AGCAGAAGCG ATAGCCAGCA ATTCTTCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	62.24	0.00e+00	1609.00
IUUC-Apl-003586	Anas platyrhynchos	87.76	0.00e+00	2429.00
IUUC-Aca-004956	Anolis carolinensis	64.20	0.00e+00	1727.00
IUUC-Ame-010753	Astyanax mexicanus	65.35	0.00e+00	809.00
IUUC-Bta-012315	Bos taurus	63.61	0.00e+00	1605.00
IUUC-Cja-019334	Callithrix jacchus	61.34	0.00e+00	1611.00
IUUC-Cfa-021254	Canis familiaris	62.24	0.00e+00	1632.00
IUUC-Cpo-021984	Cavia porcellus	59.51	0.00e+00	1510.00
IUUC-Csa-023650	Chlorocebus sabaeus	62.52	0.00e+00	1599.00
IUUC-Cho-024860	Choloepus hoffmanni	57.91	0.00e+00	1439.00
IUUC-Cin-025778	Ciona intestinalis	42.06	3.00e-125	442.00
IUUC-Csv-026313	Ciona savignyi	41.48	6.00e-131	461.00
IUUC-Dre-028096	Danio rerio	55.32	0.00e+00	1207.00
IUUC-Dno-029799	Dasypus novemcinctus	67.68	0.00e+00	1456.00
IUUC-Dor-030885	Dipodomys ordii	57.56	4.00e-129	456.00
IUUC-Ete-032918	Echinops telfairi	59.77	0.00e+00	1531.00
IUUC-Eca-034144	Equus caballus	61.67	0.00e+00	1611.00
IUUC-Eeu-034843	Erinaceus europaeus	60.35	0.00e+00	1338.00
IUUC-Fca-035948	Felis catus	61.98	0.00e+00	1603.00
IUUC-Fal-037303	Ficedula albicollis	84.45	0.00e+00	2255.00
IUUC-Gmo-039591	Gadus morhua	53.91	0.00e+00	645.00
IUUC-Gac-042646	Gasterosteus aculeatus	46.38	0.00e+00	1135.00
IUUC-Ggo-045605	Gorilla gorilla	62.65	0.00e+00	1171.00
IUUC-Hsa-046122	Homo sapiens	62.70	0.00e+00	1599.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	67.76	0.00e+00	1458.00
IUUC-Lch-050489	Latimeria chalumnae	58.24	0.00e+00	666.00
IUUC-Loc-052259	Lepisosteus oculatus	49.96	0.00e+00	1195.00
IUUC-Laf-053338	Loxodonta africana	63.17	0.00e+00	1610.00
IUUC-Mcc-055442	Macaca mulatta	62.42	0.00e+00	1600.00
IUUC-Meu-056245	Macropus eugenii	56.69	0.00e+00	666.00
IUUC-Mga-060202	Meleagris gallopavo	91.64	0.00e+00	2473.00
IUUC-Mmr-061730	Microcebus murinus	61.07	0.00e+00	1572.00
IUUC-Mdo-062880	Monodelphis domestica	64.84	0.00e+00	1710.00
IUUC-Mmu-063930	Mus musculus	61.17	0.00e+00	1510.00
IUUC-Mpu-066605	Mustela putorius furo	61.63	0.00e+00	1605.00
IUUC-Mlu-067765	Myotis lucifugus	62.39	0.00e+00	1639.00
IUUC-Nle-069183	Nomascus leucogenys	61.90	0.00e+00	1554.00
IUUC-Opr-070659	Ochotona princeps	51.74	0.00e+00	750.00
IUUC-Ont-072356	Oreochromis niloticus	48.77	0.00e+00	1211.00
IUUC-Oan-073056	Ornithorhynchus anatinus	64.77	0.00e+00	1693.00
IUUC-Ocu-073881	Oryctolagus cuniculus	62.22	0.00e+00	1675.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.27	2.00e-34	140.00
IUUC-Oga-088343	Otolemur garnettii	63.34	0.00e+00	1627.00
IUUC-Oar-089257	Ovis aries	62.97	0.00e+00	1640.00
IUUC-Ptr-090497	Pan troglodytes	62.47	0.00e+00	1592.00
IUUC-Pan-092638	Papio anubis	61.97	0.00e+00	1583.00
IUUC-Psi-093096	Pelodiscus sinensis	74.03	0.00e+00	1934.00
IUUC-Pma-094571	Petromyzon marinus	40.72	1.00e-79	290.00
IUUC-Pfo-096742	Poecilia formosa	47.13	0.00e+00	1162.00
IUUC-Pab-098153	Pongo abelii	61.47	0.00e+00	1599.00
IUUC-Pca-100957	Procavia capensis	59.28	0.00e+00	1482.00
IUUC-Pva-102439	Pteropus vampyrus	62.45	0.00e+00	1646.00
IUUC-Rno-105891	Rattus norvegicus	61.29	0.00e+00	1501.00
IUUC-Sha-107181	Sarcophilus harrisii	65.92	0.00e+00	1699.00
IUUC-Ssc-115413	Sus scrofa	62.87	0.00e+00	1633.00
IUUC-Tgu-117082	Taeniopygia guttata	83.11	0.00e+00	2173.00
IUUC-Tru-118491	Takifugu rubripes	62.25	0.00e+00	738.00
IUUC-Tsy-119629	Tarsius syrichta	71.58	9.00e-125	441.00
IUUC-Tni-120240	Tetraodon nigroviridis	62.65	0.00e+00	767.00
IUUC-Tbe-127673	Tupaia belangeri	55.44	0.00e+00	1270.00
IUUC-Ttr-128562	Tursiops truncatus	60.17	0.00e+00	1523.00
IUUC-Vpa-130596	Vicugna pacos	67.16	0.00e+00	1239.00
IUUC-Xtr-132469	Xenopus tropicalis	54.43	0.00e+00	1411.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence