iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041405

Ensembl Protein ID

ENSGACP00000019424.1

UniProt Accession

G3PP91; G3PP91_GASAC

Protein Name

Protein HIRA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000014707.1	ENSGACT00000019462.1	ENSGACP00000019424.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-19	69.1	128	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtg 33
           Ht++v ++a+  +d  l+s+s D+ti +W+ r++
   Q: 128  HTGDVMDVAWspHDVWLASCSVDNTIVIWNARKF 161
           9**********655999*************8766 PP

Organism

Gasterosteus aculeatus

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MKLLKPSWVS HNGKPIFSVD IHPDGTKFAT GGQGEDSGKV MIWNMPVLRD EDEKNESIPM 60
LCQMDNHLAC VNCVRWSNNG LYLASGGDDK LVMVWKRAAF IGPSTVFGSS SKLANVEQWR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAGACTCT GCGGGGAGGA GGAGGGGGGG GGAGAGAGAG AGCTGCCGCG GAAATGGAGT 60
TGAACCTCCA AAACAACAAA GTGTCGCACG GAGTTTGAGC CAAAGGCAGC AGGACGAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	37.96	8.00e-82	298.00
IUUC-Aml-001723	Ailuropoda melanoleuca	63.28	0.00e+00	1141.00
IUUC-Atr-003132	Amborella trichopoda	40.00	7.00e-85	308.00
IUUC-Apl-003197	Anas platyrhynchos	62.97	0.00e+00	1177.00
IUUC-Aca-004733	Anolis carolinensis	61.52	0.00e+00	1190.00
IUUC-Aly-005446	Arabidopsis lyrata	40.74	4.00e-79	289.00
IUUC-Ath-007627	Arabidopsis thaliana	36.90	7.00e-82	299.00
IUUC-Ago-007766	Ashbya gossypii	28.65	3.00e-56	213.00
IUUC-Acl-008104	Aspergillus clavatus	32.24	4.00e-59	223.00
IUUC-Afl-008591	Aspergillus flavus	28.90	2.00e-57	218.00
IUUC-Afu-008781	Aspergillus fumigatus	32.27	9.00e-53	202.00
IUUC-Ani-009272	Aspergillus nidulans	30.38	8.00e-51	195.00
IUUC-Ang-009655	Aspergillus niger	33.00	4.00e-60	226.00
IUUC-Aor-010119	Aspergillus oryzae	28.90	2.00e-57	217.00
IUUC-Ate-010530	Aspergillus terreus	28.54	6.00e-54	206.00
IUUC-Ame-011147	Astyanax mexicanus	92.08	1.00e-51	194.00
IUUC-Bgr-012237	Blumeria graminis	31.75	4.00e-58	219.00
IUUC-Bta-013320	Bos taurus	62.22	0.00e+00	1157.00
IUUC-Bci-013795	Botrytis cinerea	34.01	1.00e-63	238.00
IUUC-Bdi-014075	Brachypodium distachyon	40.42	5.00e-85	309.00
IUUC-Bol-016440	Brassica oleracea	41.47	1.00e-82	301.00
IUUC-Bra-016651	Brassica rapa	41.58	2.00e-83	304.00
IUUC-Cel-018692	Caenorhabditis elegans	37.87	3.00e-70	260.00
IUUC-Cja-018987	Callithrix jacchus	62.27	0.00e+00	1075.00
IUUC-Cfa-020132	Canis familiaris	62.83	0.00e+00	1144.00
IUUC-Cpo-021484	Cavia porcellus	63.41	0.00e+00	1172.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	33.87	2.00e-54	207.00
IUUC-Csa-023081	Chlorocebus sabaeus	63.11	0.00e+00	1159.00
IUUC-Cin-025182	Ciona intestinalis	54.22	1.00e-145	510.00
IUUC-Csv-026154	Ciona savignyi	52.16	2.00e-143	503.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	32.99	2.00e-61	231.00
IUUC-Cne-026891	Cryptococcus neoformans	39.19	4.00e-78	286.00
IUUC-Cme-027349	Cyanidioschyzon merolae	32.69	5.00e-48	186.00
IUUC-Dre-027655	Danio rerio	72.51	0.00e+00	1352.00
IUUC-Dno-029557	Dasypus novemcinctus	56.86	0.00e+00	706.00
IUUC-Dor-030687	Dipodomys ordii	65.12	2.00e-168	586.00
IUUC-Dse-031334	Dothistroma septosporum	30.93	5.00e-60	226.00
IUUC-Dme-031746	Drosophila melanogaster	51.57	4.00e-147	515.00
IUUC-Ete-032384	Echinops telfairi	58.81	0.00e+00	1051.00
IUUC-Eca-033430	Equus caballus	62.99	0.00e+00	1140.00
IUUC-Fca-036121	Felis catus	63.10	0.00e+00	1145.00
IUUC-Fal-036817	Ficedula albicollis	62.05	0.00e+00	1181.00
IUUC-Fox-037906	Fusarium oxysporum	32.90	3.00e-64	239.00
IUUC-Fso-038409	Fusarium solani	32.91	8.00e-64	238.00
IUUC-Ggr-040016	Gaeumannomyces graminis	33.25	2.00e-65	244.00
IUUC-Gga-040936	Gallus gallus	62.76	0.00e+00	1226.00
IUUC-Gma-044252	Glycine max	39.63	5.00e-83	302.00
IUUC-Ggo-045430	Gorilla gorilla	63.08	0.00e+00	1159.00
IUUC-Hsa-046442	Homo sapiens	63.24	0.00e+00	1166.00
IUUC-Hvu-047587	Hordeum vulgare	39.64	3.00e-72	266.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	86.67	6.00e-155	539.00
IUUC-Kpa-049145	Komagataella pastoris	30.96	1.00e-56	215.00
IUUC-Lch-050474	Latimeria chalumnae	73.48	0.00e+00	699.00
IUUC-Lpe-051209	Leersia perrieri	34.12	2.00e-78	287.00
IUUC-Loc-052119	Lepisosteus oculatus	68.80	0.00e+00	1261.00
IUUC-Lma-053237	Leptosphaeria maculans	33.33	2.00e-62	234.00
IUUC-Laf-053718	Loxodonta africana	63.19	0.00e+00	1169.00
IUUC-Mcc-055621	Macaca mulatta	61.93	0.00e+00	1074.00
IUUC-Mor-057090	Magnaporthe oryzae	33.33	5.00e-64	239.00
IUUC-Mpo-057364	Magnaporthe poae	33.76	1.00e-66	248.00
IUUC-Mtr-058691	Medicago truncatula	34.61	1.00e-82	301.00
IUUC-Mla-058914	Melampsora laricipopulina	36.72	2.00e-83	303.00
IUUC-Mga-060181	Meleagris gallopavo	61.74	0.00e+00	1187.00
IUUC-Mvi-060432	Microbotryum violaceum	37.03	1.00e-68	254.00
IUUC-Mmr-060871	Microcebus murinus	62.95	0.00e+00	1173.00
IUUC-Mdo-062301	Monodelphis domestica	60.98	0.00e+00	1156.00
IUUC-Mmu-063888	Mus musculus	61.65	0.00e+00	1168.00
IUUC-Mac-065137	Musa acuminata	37.37	2.00e-84	307.00
IUUC-Mpu-066732	Mustela putorius furo	63.21	0.00e+00	1150.00
IUUC-Mlu-067542	Myotis lucifugus	61.30	0.00e+00	1127.00
IUUC-Nfi-068396	Neosartorya fischeri	32.87	7.00e-53	202.00
IUUC-Ncr-068842	Neurospora crassa	32.74	1.00e-65	244.00
IUUC-Nle-070156	Nomascus leucogenys	62.82	0.00e+00	1162.00
IUUC-Ont-072105	Oreochromis niloticus	83.22	0.00e+00	1591.00
IUUC-Ocu-074962	Oryctolagus cuniculus	63.09	0.00e+00	1152.00
IUUC-Oba-075178	Oryza barthii	40.68	4.00e-85	309.00
IUUC-Obr-076399	Oryza brachyantha	40.94	9.00e-86	311.00
IUUC-Ogu-078797	Oryza glumaepatula	40.68	4.00e-85	309.00
IUUC-Oin-080085	Oryza indica	39.35	2.00e-72	267.00
IUUC-Olo-081048	Oryza longistaminata	38.72	1.00e-60	228.00
IUUC-Ome-081324	Oryza meridionalis	40.68	4.00e-85	309.00
IUUC-Oni-082548	Oryza nivara	40.68	4.00e-85	309.00
IUUC-Opu-084008	Oryza punctata	41.21	4.00e-85	309.00
IUUC-Oru-084339	Oryza rufipogon	40.68	5.00e-85	309.00
IUUC-Osa-085782	Oryza sativa	40.68	5.00e-85	309.00
IUUC-Ola-087302	Oryzias latipes	74.52	0.00e+00	1390.00
IUUC-Olu-087611	Ostreococcus lucimarinus	40.05	1.00e-81	298.00
IUUC-Oga-087935	Otolemur garnettii	62.59	0.00e+00	1132.00
IUUC-Oar-089229	Ovis aries	60.86	0.00e+00	635.00
IUUC-Ptr-090715	Pan troglodytes	63.14	0.00e+00	1164.00
IUUC-Pan-092318	Papio anubis	62.94	0.00e+00	1133.00
IUUC-Psi-094053	Pelodiscus sinensis	62.22	0.00e+00	1182.00
IUUC-Pno-094985	Phaeosphaeria nodorum	30.81	5.00e-54	206.00
IUUC-Ppa-095819	Physcomitrella patens	38.97	1.00e-80	295.00
IUUC-Pfo-096857	Poecilia formosa	79.28	0.00e+00	1498.00
IUUC-Pab-098047	Pongo abelii	63.14	0.00e+00	1162.00
IUUC-Pop-099587	Populus trichocarpa	40.94	3.00e-83	303.00
IUUC-Pca-100558	Procavia capensis	59.45	7.00e-120	425.00
IUUC-Ppe-101261	Prunus persica	35.74	1.00e-85	311.00
IUUC-Pva-102683	Pteropus vampyrus	63.04	0.00e+00	1183.00
IUUC-Pgr-103660	Puccinia graminis	33.66	2.00e-72	267.00
IUUC-Ptt-103900	Puccinia triticina	34.62	4.00e-74	272.00
IUUC-Pte-104209	Pyrenophora teres	33.33	5.00e-61	229.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	33.33	2.00e-60	228.00
IUUC-Rno-105566	Rattus norvegicus	61.65	0.00e+00	1172.00
IUUC-Sce-106291	Saccharomyces cerevisiae	29.43	2.00e-60	227.00
IUUC-Sha-107514	Sarcophilus harrisii	58.92	0.00e+00	1040.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	39.15	3.00e-77	283.00
IUUC-Spo-108162	Schizosaccharomyces pombe	38.36	8.00e-74	271.00
IUUC-Smo-109533	Selaginella moellendorffii	36.92	7.00e-87	315.00
IUUC-Sit-109980	Setaria italica	41.36	4.00e-86	313.00
IUUC-Sly-111547	Solanum lycopersicum	35.61	8.00e-84	305.00
IUUC-Stu-112705	Solanum tuberosum	40.42	6.00e-84	306.00
IUUC-Sar-113222	Sorex araneus	65.78	0.00e+00	699.00
IUUC-Sbi-114272	Sorghum bicolor	42.15	1.00e-86	315.00
IUUC-Sre-115061	Sporisorium reilianum	34.02	3.00e-72	266.00
IUUC-Ssc-116364	Sus scrofa	61.79	0.00e+00	1178.00
IUUC-Tgu-116645	Taeniopygia guttata	62.83	0.00e+00	1201.00
IUUC-Tru-117590	Takifugu rubripes	80.60	0.00e+00	1524.00
IUUC-Tsy-119212	Tarsius syrichta	86.96	4.00e-170	592.00
IUUC-Tni-119915	Tetraodon nigroviridis	80.65	0.00e+00	1501.00
IUUC-Tca-121765	Theobroma cacao	40.68	2.00e-83	304.00
IUUC-Tre-121887	Trichoderma reesei	32.91	2.00e-57	218.00
IUUC-Tvi-122262	Trichoderma virens	32.40	6.00e-57	216.00
IUUC-Tae-124148	Triticum aestivum	44.51	3.00e-37	150.00
IUUC-Tur-126483	Triticum urartu	41.73	9.00e-86	311.00
IUUC-Tme-127202	Tuber melanosporum	31.54	4.00e-51	196.00
IUUC-Tbe-127350	Tupaia belangeri	69.21	8.00e-136	478.00
IUUC-Ttr-129077	Tursiops truncatus	59.14	0.00e+00	1104.00
IUUC-Uma-129465	Ustilago maydis	33.95	1.00e-72	268.00
IUUC-Vda-129844	Verticillium dahliae	34.02	5.00e-63	236.00
IUUC-Vvi-131397	Vitis vinifera	40.47	3.00e-84	306.00
IUUC-Xtr-132057	Xenopus tropicalis	59.88	0.00e+00	1134.00
IUUC-Xma-134139	Xiphophorus maculatus	76.46	0.00e+00	882.00
IUUC-Yli-134424	Yarrowia lipolytica	31.82	9.00e-64	238.00
IUUC-Zma-135506	Zea mays	40.26	4.00e-85	310.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence