iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035752

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02019426

Gene Name

KLHL20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000013180.3	ENSFCAT00000013184.3	ENSFCAP00000012223.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.00e-22	78.8	63	130
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.30e-11	43.5	162	193

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+lvvg +++ ah+++L+a+S++F+a+f++el es+ + +v+i+d++  +++ l++F Yt++++ +e
   Q: 63   CDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESR-QTEVVIRDIDERAMELLIDFAYTSQITVEE 130
           9*************************************.*************************98765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fAd+++c++L   a++f++++F+
   Q: 162  PSNCLGIRAFADTHSCRELLRIADKFTQHNFQ 193
           89*****************************6 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MRRCTNIRPG ETGMDVTSRC TLGDPNKLPE GVPQPARMPY ISDKHPRQTL EVINLLRKHR 60
ELCDVVLVVG AKKIYAHRVI LSACSPYFRA MFTGELAESR QTEVVIRDID ERAMELLIDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAGAGTGTG GTGAAGGGTA CTTTTCATGG TGCATGGAAG GAAAGCCAAT GCGCAGGTAG 60
GCTTTTAGGA GGAAAACCTT CAGTTTCACT GATTGAAATT CAACATGGAA TAATTCAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0005802--C:trans-Golgi network
GO:0019964--F:interferon-gamma binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006895--P:Golgi to endosome transport
GO:0043066--P:negative regulation of apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990390--P:protein K33-linked ubiquitination
GO:0035455--P:response to interferon-alpha

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001974	Ailuropoda melanoleuca	98.54	0.00e+00	1122.00
IUUC-Apl-003481	Anas platyrhynchos	98.36	0.00e+00	1118.00
IUUC-Aca-004877	Anolis carolinensis	98.18	0.00e+00	1114.00
IUUC-Ame-011440	Astyanax mexicanus	97.76	0.00e+00	1090.00
IUUC-Bta-012603	Bos taurus	98.91	0.00e+00	1123.00
IUUC-Bol-016130	Brassica oleracea	27.14	8.00e-16	79.00
IUUC-Bra-016881	Brassica rapa	27.27	6.00e-17	82.80
IUUC-Cel-018464	Caenorhabditis elegans	59.14	0.00e+00	665.00
IUUC-Cja-019119	Callithrix jacchus	98.91	0.00e+00	1123.00
IUUC-Cfa-020169	Canis familiaris	98.91	0.00e+00	1123.00
IUUC-Cpo-021519	Cavia porcellus	98.72	0.00e+00	1120.00
IUUC-Csa-024173	Chlorocebus sabaeus	98.91	0.00e+00	1123.00
IUUC-Cho-024820	Choloepus hoffmanni	95.78	0.00e+00	786.00
IUUC-Cin-025270	Ciona intestinalis	74.16	0.00e+00	811.00
IUUC-Csv-026308	Ciona savignyi	73.98	0.00e+00	818.00
IUUC-Dre-027423	Danio rerio	97.94	0.00e+00	1090.00
IUUC-Dno-029350	Dasypus novemcinctus	98.54	0.00e+00	1118.00
IUUC-Dor-031011	Dipodomys ordii	100.00	3.00e-165	575.00
IUUC-Dme-032170	Drosophila melanogaster	81.20	0.00e+00	867.00
IUUC-Ete-033187	Echinops telfairi	99.77	0.00e+00	877.00
IUUC-Eca-033751	Equus caballus	98.91	0.00e+00	1122.00
IUUC-Eeu-034901	Erinaceus europaeus	98.54	0.00e+00	1120.00
IUUC-Fal-037630	Ficedula albicollis	98.18	0.00e+00	1117.00
IUUC-Gmo-039481	Gadus morhua	96.17	0.00e+00	1099.00
IUUC-Gga-040971	Gallus gallus	98.36	0.00e+00	1118.00
IUUC-Gac-042602	Gasterosteus aculeatus	96.53	0.00e+00	1102.00
IUUC-Ggo-044588	Gorilla gorilla	98.91	0.00e+00	1122.00
IUUC-Hsa-046641	Homo sapiens	98.91	0.00e+00	1123.00
IUUC-Itr-048394	Ictidomys tridecemlineatus	98.91	0.00e+00	1123.00
IUUC-Lch-049968	Latimeria chalumnae	97.99	0.00e+00	1115.00
IUUC-Loc-052720	Lepisosteus oculatus	96.90	0.00e+00	1107.00
IUUC-Laf-054156	Loxodonta africana	98.91	0.00e+00	1122.00
IUUC-Mcc-054629	Macaca mulatta	98.91	0.00e+00	1123.00
IUUC-Meu-056605	Macropus eugenii	99.36	0.00e+00	644.00
IUUC-Mga-060014	Meleagris gallopavo	97.62	0.00e+00	1099.00
IUUC-Mmr-060814	Microcebus murinus	98.72	0.00e+00	1119.00
IUUC-Mdo-062242	Monodelphis domestica	98.36	0.00e+00	1117.00
IUUC-Mmu-064309	Mus musculus	98.91	0.00e+00	1123.00
IUUC-Mpu-066587	Mustela putorius furo	98.91	0.00e+00	1123.00
IUUC-Mlu-066958	Myotis lucifugus	95.10	0.00e+00	1072.00
IUUC-Nle-069059	Nomascus leucogenys	97.26	0.00e+00	1098.00
IUUC-Ont-072129	Oreochromis niloticus	96.53	0.00e+00	1103.00
IUUC-Oan-073073	Ornithorhynchus anatinus	98.17	0.00e+00	1112.00
IUUC-Ocu-073909	Oryctolagus cuniculus	97.99	0.00e+00	1113.00
IUUC-Ola-086392	Oryzias latipes	95.82	0.00e+00	1094.00
IUUC-Oga-088693	Otolemur garnettii	98.36	0.00e+00	1120.00
IUUC-Oar-089905	Ovis aries	98.72	0.00e+00	1120.00
IUUC-Ptr-091059	Pan troglodytes	98.91	0.00e+00	1123.00
IUUC-Pan-091833	Papio anubis	98.30	0.00e+00	718.00
IUUC-Psi-093499	Pelodiscus sinensis	98.36	0.00e+00	1115.00
IUUC-Pma-094404	Petromyzon marinus	75.72	0.00e+00	849.00
IUUC-Pfo-096891	Poecilia formosa	96.90	0.00e+00	1106.00
IUUC-Pab-097715	Pongo abelii	93.98	0.00e+00	1054.00
IUUC-Pva-102944	Pteropus vampyrus	80.84	0.00e+00	889.00
IUUC-Rno-104878	Rattus norvegicus	98.91	0.00e+00	1123.00
IUUC-Sha-107444	Sarcophilus harrisii	98.36	0.00e+00	1118.00
IUUC-Ssc-115565	Sus scrofa	98.90	0.00e+00	1120.00
IUUC-Tgu-116902	Taeniopygia guttata	98.18	0.00e+00	1116.00
IUUC-Tru-118692	Takifugu rubripes	96.72	0.00e+00	1103.00
IUUC-Tsy-119031	Tarsius syrichta	95.01	0.00e+00	1011.00
IUUC-Tbe-127517	Tupaia belangeri	99.81	0.00e+00	1114.00
IUUC-Ttr-128366	Tursiops truncatus	98.91	0.00e+00	1123.00
IUUC-Vpa-130465	Vicugna pacos	99.82	0.00e+00	1120.00
IUUC-Xtr-132243	Xenopus tropicalis	97.45	0.00e+00	1108.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence