iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-066958

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02018269

Gene Name

KLHL20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000010997.2	ENSMLUT00000010991.2	ENSMLUP00000010016.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.10e-21	75.6	70	137
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.60e-11	43.3	169	200

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           + v+lvvg +++ ah+++L+a+S++F+a+f++el es+ + +v+i+d++  +++ l++F Yt++++ +e
   Q: 70   CNVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESR-QTEVVIRDIDERAMELLIDFAYTSQITVEE 137
           78************************************.*************************98765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fAd+++c++L   a++f++++F+
   Q: 169  PSNCLGIRAFADTHSCRELLRIADKFTQHNFQ 200
           89*****************************6 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

ETSWPMRRSR NSPGERGLTL ELKTNSVLRE DFKKLPEGVP QPARMPYISD KHPRQTLEVI 60
NLLRKHRELC NVVLVVGAKK IYAHRVILSA CSPYFRAMFT GELAESRQTE VVIRDIDERA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAACTTCGT GGCCCATGCG CAGAAGTCGG TATTTTGTGG AAGAGCCACA CTCAAGGGGC 60
CAAAGAGCCG CATGTGGCTC GGAGACGCCC GTTTGCGCCC CCTGGGCTTA AAAAAGTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0005802--C:trans-Golgi network
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006895--P:Golgi to endosome transport
GO:0043066--P:negative regulation of apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990390--P:protein K33-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001974	Ailuropoda melanoleuca	96.21	0.00e+00	1202.00
IUUC-Apl-003481	Anas platyrhynchos	96.22	0.00e+00	1203.00
IUUC-Aca-004877	Anolis carolinensis	96.05	0.00e+00	1202.00
IUUC-Aly-005957	Arabidopsis lyrata	36.30	7.00e-40	158.00
IUUC-Ath-007066	Arabidopsis thaliana	35.93	5.00e-39	155.00
IUUC-Aor-010180	Aspergillus oryzae	24.65	3.00e-09	56.20
IUUC-Ame-011440	Astyanax mexicanus	98.28	0.00e+00	1192.00
IUUC-Bta-012603	Bos taurus	96.55	0.00e+00	1206.00
IUUC-Bol-016130	Brassica oleracea	27.14	8.00e-16	79.00
IUUC-Bra-016881	Brassica rapa	27.27	5.00e-17	83.20
IUUC-Cel-018464	Caenorhabditis elegans	61.06	0.00e+00	712.00
IUUC-Cja-019119	Callithrix jacchus	96.55	0.00e+00	1206.00
IUUC-Cfa-020169	Canis familiaris	96.55	0.00e+00	1206.00
IUUC-Cpo-021519	Cavia porcellus	96.38	0.00e+00	1203.00
IUUC-Csa-024173	Chlorocebus sabaeus	96.55	0.00e+00	1206.00
IUUC-Cho-024820	Choloepus hoffmanni	94.58	0.00e+00	782.00
IUUC-Cin-025270	Ciona intestinalis	76.81	0.00e+00	886.00
IUUC-Csv-026308	Ciona savignyi	77.18	0.00e+00	891.00
IUUC-Dre-027423	Danio rerio	98.45	0.00e+00	1193.00
IUUC-Dno-029350	Dasypus novemcinctus	96.22	0.00e+00	1201.00
IUUC-Dor-030659	Dipodomys ordii	50.27	1.00e-149	523.00
IUUC-Dme-032170	Drosophila melanogaster	80.77	0.00e+00	960.00
IUUC-Ete-033187	Echinops telfairi	95.12	0.00e+00	830.00
IUUC-Eca-033751	Equus caballus	96.55	0.00e+00	1205.00
IUUC-Eeu-034901	Erinaceus europaeus	96.22	0.00e+00	1203.00
IUUC-Fca-035752	Felis catus	95.10	0.00e+00	1072.00
IUUC-Fal-037630	Ficedula albicollis	96.21	0.00e+00	1199.00
IUUC-Gmo-039481	Gadus morhua	94.56	0.00e+00	1191.00
IUUC-Gga-040971	Gallus gallus	96.22	0.00e+00	1204.00
IUUC-Gac-042602	Gasterosteus aculeatus	94.89	0.00e+00	1193.00
IUUC-Ggo-044588	Gorilla gorilla	96.55	0.00e+00	1206.00
IUUC-Hsa-046641	Homo sapiens	96.55	0.00e+00	1206.00
IUUC-Itr-048394	Ictidomys tridecemlineatus	96.54	0.00e+00	1203.00
IUUC-Lch-049968	Latimeria chalumnae	95.72	0.00e+00	1201.00
IUUC-Loc-052720	Lepisosteus oculatus	94.90	0.00e+00	1193.00
IUUC-Lma-053201	Leptosphaeria maculans	27.21	4.00e-09	55.50
IUUC-Laf-054156	Loxodonta africana	96.55	0.00e+00	1205.00
IUUC-Mcc-054629	Macaca mulatta	96.55	0.00e+00	1206.00
IUUC-Meu-056605	Macropus eugenii	94.87	2.00e-173	602.00
IUUC-Mga-060014	Meleagris gallopavo	95.54	0.00e+00	1185.00
IUUC-Mmr-060814	Microcebus murinus	95.74	0.00e+00	1203.00
IUUC-Mdo-062242	Monodelphis domestica	96.22	0.00e+00	1203.00
IUUC-Mmu-064309	Mus musculus	96.54	0.00e+00	1203.00
IUUC-Mpu-066587	Mustela putorius furo	96.55	0.00e+00	1206.00
IUUC-Nle-069059	Nomascus leucogenys	95.07	0.00e+00	1182.00
IUUC-Ont-072129	Oreochromis niloticus	94.89	0.00e+00	1195.00
IUUC-Oan-073073	Ornithorhynchus anatinus	96.83	0.00e+00	1199.00
IUUC-Ocu-073909	Oryctolagus cuniculus	95.89	0.00e+00	1196.00
IUUC-Ola-086392	Oryzias latipes	94.25	0.00e+00	1185.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.44	2.00e-31	129.00
IUUC-Oga-088693	Otolemur garnettii	96.21	0.00e+00	1202.00
IUUC-Oar-089905	Ovis aries	96.38	0.00e+00	1203.00
IUUC-Ptr-091059	Pan troglodytes	96.55	0.00e+00	1206.00
IUUC-Pan-091833	Papio anubis	94.62	0.00e+00	790.00
IUUC-Psi-093499	Pelodiscus sinensis	96.21	0.00e+00	1196.00
IUUC-Pma-094404	Petromyzon marinus	80.27	0.00e+00	932.00
IUUC-Pfo-096891	Poecilia formosa	95.22	0.00e+00	1197.00
IUUC-Pab-097715	Pongo abelii	92.11	0.00e+00	1137.00
IUUC-Pva-102944	Pteropus vampyrus	80.26	0.00e+00	971.00
IUUC-Rno-104878	Rattus norvegicus	96.55	0.00e+00	1206.00
IUUC-Sha-107444	Sarcophilus harrisii	96.22	0.00e+00	1204.00
IUUC-Ssc-115565	Sus scrofa	96.53	0.00e+00	1201.00
IUUC-Tgu-116902	Taeniopygia guttata	96.22	0.00e+00	1203.00
IUUC-Tru-118692	Takifugu rubripes	95.06	0.00e+00	1194.00
IUUC-Tsy-119031	Tarsius syrichta	89.14	0.00e+00	1088.00
IUUC-Tni-120531	Tetraodon nigroviridis	51.16	7.00e-153	533.00
IUUC-Tbe-127517	Tupaia belangeri	91.15	0.00e+00	1112.00
IUUC-Ttr-128366	Tursiops truncatus	96.55	0.00e+00	1206.00
IUUC-Vpa-130465	Vicugna pacos	96.22	0.00e+00	1201.00
IUUC-Vvi-131673	Vitis vinifera	34.33	4.00e-42	166.00
IUUC-Xtr-132243	Xenopus tropicalis	95.57	0.00e+00	1197.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence