iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024119

Ensembl Protein ID

ENSCSAP00000008170.1

UniProt Accession

A0A0D9RHT1; A0A0D9RHT1_CHLSB

Genbank Protein ID

ENSCSAP00000008170

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01113099

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000011985.1	ENSCSAT00000010069.1	ENSCSAP00000008170.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-23	80.2	476	505
E3 activity/RING/RING	2.10e-06	28.1	142	180

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 476  NSKISCISWssYHkNLLASSDYEGTVILWD 505
           689******9622599************** PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 142  CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 180
           ********99.888***********9555......999999****6 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MSGSRQAGSG SAGTSPGSSA ASSVTSASSS LSSSPSPPSV AASAAALVSG GATQPAGSGG 60
LGGPVRPVLV APAVSGSGGG AVSTGLSRHS CVARPSAGVG GSSSSLGSSS SLGSGSRKRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCGGCC TCGACAGCGG TAGTGTCTTC TACTCCGCTT TTTCAGTTTC CTCCGCCCCC 60
TCCGGTCGGA CGCTGTTGTG TGGTTGCCTT AAAAAAAAAC GCAACTTTAT TGTTCCTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	39.94	6.00e-126	444.00
IUUC-Aml-001265	Ailuropoda melanoleuca	100.00	0.00e+00	1253.00
IUUC-Atr-002460	Amborella trichopoda	38.52	2.00e-124	439.00
IUUC-Apl-003796	Anas platyrhynchos	98.28	0.00e+00	1159.00
IUUC-Aca-005078	Anolis carolinensis	97.26	0.00e+00	1208.00
IUUC-Aly-006014	Arabidopsis lyrata	39.94	4.00e-130	458.00
IUUC-Ath-007636	Arabidopsis thaliana	39.69	7.00e-130	457.00
IUUC-Ame-011176	Astyanax mexicanus	75.27	3.00e-70	259.00
IUUC-Bta-012595	Bos taurus	95.93	0.00e+00	1261.00
IUUC-Bdi-014152	Brachypodium distachyon	38.98	7.00e-129	454.00
IUUC-Bol-016380	Brassica oleracea	40.12	4.00e-131	461.00
IUUC-Bra-017690	Brassica rapa	39.15	1.00e-125	443.00
IUUC-Cja-018926	Callithrix jacchus	98.00	0.00e+00	1251.00
IUUC-Cfa-021088	Canis familiaris	97.54	0.00e+00	1249.00
IUUC-Cpo-022442	Cavia porcellus	97.19	0.00e+00	1222.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.45	3.00e-33	135.00
IUUC-Cho-024883	Choloepus hoffmanni	65.57	2.00e-104	373.00
IUUC-Cin-025375	Ciona intestinalis	55.24	0.00e+00	676.00
IUUC-Cme-027350	Cyanidioschyzon merolae	41.42	2.00e-78	287.00
IUUC-Dre-028453	Danio rerio	87.40	0.00e+00	1080.00
IUUC-Dno-029887	Dasypus novemcinctus	98.55	0.00e+00	1241.00
IUUC-Dor-031110	Dipodomys ordii	89.52	0.00e+00	871.00
IUUC-Ete-033016	Echinops telfairi	83.10	0.00e+00	1028.00
IUUC-Eca-034403	Equus caballus	99.31	0.00e+00	1163.00
IUUC-Eeu-034690	Erinaceus europaeus	84.35	0.00e+00	960.00
IUUC-Fca-036475	Felis catus	98.97	0.00e+00	1167.00
IUUC-Fal-037189	Ficedula albicollis	98.32	0.00e+00	1189.00
IUUC-Gmo-039245	Gadus morhua	86.95	0.00e+00	1060.00
IUUC-Gga-040806	Gallus gallus	98.06	0.00e+00	1235.00
IUUC-Gac-042177	Gasterosteus aculeatus	87.84	0.00e+00	1099.00
IUUC-Gma-044187	Glycine max	40.49	7.00e-127	447.00
IUUC-Ggo-044430	Gorilla gorilla	98.73	0.00e+00	935.00
IUUC-Hsa-045853	Homo sapiens	98.00	0.00e+00	1252.00
IUUC-Hvu-047750	Hordeum vulgare	38.42	5.00e-93	336.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	100.00	1.00e-144	505.00
IUUC-Lch-050420	Latimeria chalumnae	91.88	0.00e+00	1149.00
IUUC-Lpe-051219	Leersia perrieri	38.82	2.00e-124	439.00
IUUC-Loc-052728	Lepisosteus oculatus	91.13	0.00e+00	1104.00
IUUC-Laf-053775	Loxodonta africana	97.22	0.00e+00	1249.00
IUUC-Meu-056595	Macropus eugenii	77.93	9.00e-178	617.00
IUUC-Mtr-058555	Medicago truncatula	40.27	2.00e-133	469.00
IUUC-Mga-059646	Meleagris gallopavo	97.94	0.00e+00	1157.00
IUUC-Mmr-060990	Microcebus murinus	99.21	0.00e+00	1278.00
IUUC-Mdo-062287	Monodelphis domestica	98.71	0.00e+00	1246.00
IUUC-Mmu-064097	Mus musculus	97.70	0.00e+00	1249.00
IUUC-Mac-065240	Musa acuminata	41.22	8.00e-136	477.00
IUUC-Mpu-066612	Mustela putorius furo	98.97	0.00e+00	1169.00
IUUC-Mlu-067967	Myotis lucifugus	97.15	0.00e+00	1172.00
IUUC-Nle-069543	Nomascus leucogenys	98.15	0.00e+00	1256.00
IUUC-Opr-070366	Ochotona princeps	83.88	0.00e+00	717.00
IUUC-Ont-071522	Oreochromis niloticus	82.07	0.00e+00	1093.00
IUUC-Oan-073409	Ornithorhynchus anatinus	96.66	0.00e+00	1165.00
IUUC-Ocu-073756	Oryctolagus cuniculus	97.95	0.00e+00	1226.00
IUUC-Oba-075149	Oryza barthii	38.91	5.00e-127	449.00
IUUC-Obr-076563	Oryza brachyantha	39.32	9.00e-127	447.00
IUUC-Ogl-077701	Oryza glaberrima	39.11	5.00e-127	448.00
IUUC-Ogu-078383	Oryza glumaepatula	39.11	5.00e-127	448.00
IUUC-Oin-079965	Oryza indica	36.90	3.00e-113	402.00
IUUC-Olo-080639	Oryza longistaminata	38.65	8.00e-125	441.00
IUUC-Ome-081821	Oryza meridionalis	38.76	6.00e-115	408.00
IUUC-Oni-082622	Oryza nivara	39.11	5.00e-127	448.00
IUUC-Opu-083295	Oryza punctata	38.80	9.00e-127	447.00
IUUC-Oru-084661	Oryza rufipogon	39.11	5.00e-127	448.00
IUUC-Osa-085766	Oryza sativa	39.11	5.00e-127	448.00
IUUC-Ola-086727	Oryzias latipes	81.83	0.00e+00	1107.00
IUUC-Olu-087702	Ostreococcus lucimarinus	42.63	5.00e-68	250.00
IUUC-Oga-088215	Otolemur garnettii	96.59	0.00e+00	1227.00
IUUC-Oar-089880	Ovis aries	97.97	0.00e+00	1233.00
IUUC-Ptr-090597	Pan troglodytes	98.00	0.00e+00	1252.00
IUUC-Pan-091987	Papio anubis	98.46	0.00e+00	1259.00
IUUC-Psi-094033	Pelodiscus sinensis	97.80	0.00e+00	1165.00
IUUC-Pma-094587	Petromyzon marinus	70.56	0.00e+00	804.00
IUUC-Ppa-095256	Physcomitrella patens	39.64	4.00e-132	465.00
IUUC-Pfo-097388	Poecilia formosa	86.52	0.00e+00	1068.00
IUUC-Pab-098029	Pongo abelii	98.00	0.00e+00	1253.00
IUUC-Pop-099319	Populus trichocarpa	38.77	2.00e-130	459.00
IUUC-Pca-100846	Procavia capensis	90.50	0.00e+00	1135.00
IUUC-Ppe-101250	Prunus persica	38.45	8.00e-121	427.00
IUUC-Pva-102407	Pteropus vampyrus	97.54	0.00e+00	1239.00
IUUC-Rno-105312	Rattus norvegicus	97.69	0.00e+00	1246.00
IUUC-Sha-106514	Sarcophilus harrisii	98.92	0.00e+00	776.00
IUUC-Smo-109418	Selaginella moellendorffii	39.69	1.00e-129	457.00
IUUC-Sit-110248	Setaria italica	38.77	8.00e-128	451.00
IUUC-Sly-110964	Solanum lycopersicum	40.40	4.00e-131	462.00
IUUC-Stu-112882	Solanum tuberosum	40.64	3.00e-132	465.00
IUUC-Sar-113230	Sorex araneus	72.20	0.00e+00	803.00
IUUC-Sbi-113962	Sorghum bicolor	36.90	8.00e-123	434.00
IUUC-Ssc-115987	Sus scrofa	97.09	6.00e-179	619.00
IUUC-Tgu-116471	Taeniopygia guttata	98.39	0.00e+00	1241.00
IUUC-Tru-118231	Takifugu rubripes	87.20	0.00e+00	1050.00
IUUC-Tsy-119415	Tarsius syrichta	98.49	0.00e+00	1169.00
IUUC-Tni-120893	Tetraodon nigroviridis	83.53	0.00e+00	1062.00
IUUC-Tca-121703	Theobroma cacao	41.11	3.00e-129	455.00
IUUC-Tae-125317	Triticum aestivum	40.99	4.00e-134	471.00
IUUC-Tur-126557	Triticum urartu	40.62	4.00e-129	455.00
IUUC-Tbe-127253	Tupaia belangeri	70.69	0.00e+00	843.00
IUUC-Ttr-129100	Tursiops truncatus	97.14	0.00e+00	1137.00
IUUC-Vpa-130613	Vicugna pacos	92.44	0.00e+00	1095.00
IUUC-Vvi-130880	Vitis vinifera	40.97	6.00e-123	434.00
IUUC-Xtr-132033	Xenopus tropicalis	90.84	0.00e+00	1238.00
IUUC-Xma-133421	Xiphophorus maculatus	83.18	0.00e+00	1066.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence