iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000002521.3	ENSMMUT00000043619.2	ENSMMUP00000036615.2
ENSMMUG00000002521.3	ENSMMUT00000043618.2	ENSMMUP00000036614.2
ENSMMUG00000002521.3	ENSMMUT00000003587.3	ENSMMUP00000003391.3
ENSMMUG00000002521.3	ENSMMUT00000016131.3	ENSMMUP00000015118.3
ENSMMUG00000002521.3	ENSMMUT00000061816.1	ENSMMUP00000047348.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-29	100.9	571	603
UBD/Beta-Prp	7.40e-46	157.8	567	781

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt++vW+++
   Q: 571  GHTDAVWGLAYsaaH-QRLLSCSADGTLRVWNTT 603
           8**********9853.89**************76 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk......ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t++vw+     +  ++       g  +sv ++s++p  +++v+  +  +  ++++et+q 
   Q: 567  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRVWNTTEVAPALSVFndtqelGIPASVDLVSSDP--SHMVASFSKGYTSIFNMETQQR 653
           5689******************************8776655555551444555666666677777..8888888899************ PP
   S: 129  lee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           + +      t ++ +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++
   Q: 654  ILTlesnvdTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLES 741
           ***9999998888888999999***99**************************98.********************************* PP
   S: 212  gecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 742  KTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 781
           ***********999999******************97655 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDEQAGPGVF FSNNHPGAGG AKGLGPLAEA AAAGDGAAAA AAAAGAARAQ YSLPGILHFL 60
QHEWARFEVE RAQWEVERAE LQAQIAFLQG ERKGQENLKK DLVRRIKMLE YALKQERAKY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTGGGGTG TGGGCGGGAG CGGCGGAGGG AGGAGGAGGC GCTGCTTGCC GCCGCTGTTG 60
CCTCCGCTGC TGGGCGCCGG GGCAGCTTCC CGGGTATCTG CAGCCGCCAT GGACGAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

KEGG

mcc:708491

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	97.96	0.00e+00	1364.00
IUUC-Apl-003927	Anas platyrhynchos	88.37	0.00e+00	1130.00
IUUC-Aca-004933	Anolis carolinensis	81.15	0.00e+00	1158.00
IUUC-Ate-010457	Aspergillus terreus	26.49	6.00e-28	119.00
IUUC-Ame-010997	Astyanax mexicanus	73.03	0.00e+00	1072.00
IUUC-Bta-013077	Bos taurus	95.66	0.00e+00	1378.00
IUUC-Cja-018973	Callithrix jacchus	97.45	0.00e+00	1397.00
IUUC-Cfa-020988	Canis familiaris	94.31	0.00e+00	1232.00
IUUC-Cpo-022496	Cavia porcellus	95.15	0.00e+00	1379.00
IUUC-Csa-023829	Chlorocebus sabaeus	98.85	0.00e+00	1400.00
IUUC-Dre-028560	Danio rerio	68.58	0.00e+00	972.00
IUUC-Dno-029742	Dasypus novemcinctus	89.92	0.00e+00	1309.00
IUUC-Dor-030721	Dipodomys ordii	87.63	0.00e+00	1259.00
IUUC-Eca-033760	Equus caballus	97.87	0.00e+00	1288.00
IUUC-Eeu-034953	Erinaceus europaeus	97.40	0.00e+00	755.00
IUUC-Fca-036530	Felis catus	97.30	0.00e+00	1289.00
IUUC-Fal-037353	Ficedula albicollis	81.98	0.00e+00	901.00
IUUC-Gga-040132	Gallus gallus	88.30	0.00e+00	1144.00
IUUC-Gac-041713	Gasterosteus aculeatus	73.34	0.00e+00	1060.00
IUUC-Ggo-045455	Gorilla gorilla	86.55	0.00e+00	1192.00
IUUC-Hsa-046415	Homo sapiens	97.32	0.00e+00	1393.00
IUUC-Lch-050475	Latimeria chalumnae	81.90	0.00e+00	1188.00
IUUC-Loc-051859	Lepisosteus oculatus	77.71	0.00e+00	1133.00
IUUC-Laf-053537	Loxodonta africana	95.15	0.00e+00	1385.00
IUUC-Meu-055946	Macropus eugenii	70.24	0.00e+00	912.00
IUUC-Mga-059694	Meleagris gallopavo	88.35	0.00e+00	1122.00
IUUC-Mmr-060768	Microcebus murinus	97.45	0.00e+00	1408.00
IUUC-Mdo-061901	Monodelphis domestica	87.53	0.00e+00	1316.00
IUUC-Mmu-064154	Mus musculus	95.03	0.00e+00	1368.00
IUUC-Mpu-065827	Mustela putorius furo	91.27	0.00e+00	1371.00
IUUC-Mlu-067102	Myotis lucifugus	97.55	0.00e+00	1354.00
IUUC-Ncr-068831	Neurospora crassa	39.60	7.00e-22	99.40
IUUC-Nle-070008	Nomascus leucogenys	98.86	0.00e+00	1303.00
IUUC-Opr-071067	Ochotona princeps	61.62	1.00e-178	619.00
IUUC-Ont-072025	Oreochromis niloticus	72.92	0.00e+00	1049.00
IUUC-Oan-072950	Ornithorhynchus anatinus	91.77	0.00e+00	1167.00
IUUC-Ocu-074316	Oryctolagus cuniculus	96.87	0.00e+00	1273.00
IUUC-Ola-087279	Oryzias latipes	70.83	0.00e+00	1020.00
IUUC-Oga-088284	Otolemur garnettii	95.66	0.00e+00	1378.00
IUUC-Oar-090304	Ovis aries	96.17	0.00e+00	1383.00
IUUC-Ptr-091052	Pan troglodytes	97.45	0.00e+00	1395.00
IUUC-Pan-092270	Papio anubis	92.88	0.00e+00	1357.00
IUUC-Psi-093907	Pelodiscus sinensis	88.33	0.00e+00	1049.00
IUUC-Pfo-097042	Poecilia formosa	71.95	0.00e+00	1130.00
IUUC-Pab-098110	Pongo abelii	97.45	0.00e+00	1395.00
IUUC-Pca-100266	Procavia capensis	83.11	0.00e+00	987.00
IUUC-Pva-102824	Pteropus vampyrus	94.77	0.00e+00	1358.00
IUUC-Pgr-103483	Puccinia graminis	37.28	5.00e-57	216.00
IUUC-Rno-105638	Rattus norvegicus	95.03	0.00e+00	1374.00
IUUC-Sha-107004	Sarcophilus harrisii	88.40	0.00e+00	1129.00
IUUC-Ssc-115280	Sus scrofa	96.30	0.00e+00	1390.00
IUUC-Tgu-116759	Taeniopygia guttata	89.06	0.00e+00	1151.00
IUUC-Tru-117944	Takifugu rubripes	72.80	0.00e+00	1055.00
IUUC-Tsy-119405	Tarsius syrichta	86.75	0.00e+00	1086.00
IUUC-Tni-120571	Tetraodon nigroviridis	72.24	0.00e+00	1061.00
IUUC-Vpa-130294	Vicugna pacos	97.58	0.00e+00	1276.00
IUUC-Xma-134233	Xiphophorus maculatus	68.50	0.00e+00	909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence