iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054511

UUCD1 version

UUC-LoA-00299

Ensembl Protein ID

ENSLAFP00000007235.4

UniProt Accession

G3T265; G3T265_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KLHL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000008616.4	ENSLAFT00000008615.4	ENSLAFP00000007235.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.10e-20	72.0	61	124
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.50e-10	39.5	160	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dvil+v+ +ef++h++vLaa+S +F+a+f ++l+e+  +++++ik+v++e + +ll++ Yt+k+
   Q: 61   TDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKY-EKRIVIKGVDAEIMHTLLDYTYTSKA 124
           7***********************************97.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           +eNc+gilr+Ad+++++ Lk++++++i ++F
   Q: 160  PENCVGILRLADTHSLDSLKKQVQSYIVQNF 190
           89****************************9 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGDVVEKSLE GPLAPSADEA TRKRGDLVEI LNEDKVKFDD TGLSLMLQNG LETLRMENAL 60
TDVILCVDIQ EFSCHRVVLA AASNYFRAMF CNDLKEKYEK RIVIKGVDAE IMHTLLDYTY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTGACG TGGTAGAGAA GAGTTTGGAA GGGCCTCTGG CCCCTTCTGC AGATGAGGCC 60
ACCAGGAAAA GGGGGGACCT GGTAGAAATC TTAAATGAGG ATAAGGTAAA ATTTGATGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	96.72	0.00e+00	1241.00
IUUC-Apl-003490	Anas platyrhynchos	84.59	0.00e+00	1105.00
IUUC-Aca-005136	Anolis carolinensis	83.25	0.00e+00	1063.00
IUUC-Ame-010886	Astyanax mexicanus	67.48	0.00e+00	835.00
IUUC-Bta-013473	Bos taurus	96.39	0.00e+00	1207.00
IUUC-Cja-018888	Callithrix jacchus	96.23	0.00e+00	1231.00
IUUC-Cpo-021761	Cavia porcellus	88.01	0.00e+00	1111.00
IUUC-Csa-023206	Chlorocebus sabaeus	96.39	0.00e+00	1234.00
IUUC-Cin-025367	Ciona intestinalis	41.12	1.00e-132	466.00
IUUC-Csv-026076	Ciona savignyi	41.39	4.00e-126	445.00
IUUC-Dre-027948	Danio rerio	72.96	0.00e+00	905.00
IUUC-Dno-030045	Dasypus novemcinctus	96.23	0.00e+00	1233.00
IUUC-Dor-030839	Dipodomys ordii	87.87	0.00e+00	1097.00
IUUC-Ete-033161	Echinops telfairi	92.81	1.00e-158	553.00
IUUC-Eca-033608	Equus caballus	96.07	0.00e+00	1207.00
IUUC-Eeu-034640	Erinaceus europaeus	93.93	0.00e+00	1211.00
IUUC-Fca-036065	Felis catus	96.39	0.00e+00	1239.00
IUUC-Fal-036949	Ficedula albicollis	84.65	0.00e+00	1087.00
IUUC-Gmo-039661	Gadus morhua	58.32	4.00e-176	610.00
IUUC-Gga-040740	Gallus gallus	82.95	0.00e+00	1090.00
IUUC-Gac-042413	Gasterosteus aculeatus	61.58	0.00e+00	787.00
IUUC-Ggo-045167	Gorilla gorilla	96.23	0.00e+00	1232.00
IUUC-Hsa-046120	Homo sapiens	96.23	0.00e+00	1232.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	95.41	0.00e+00	1223.00
IUUC-Lch-049709	Latimeria chalumnae	79.15	0.00e+00	1042.00
IUUC-Loc-052239	Lepisosteus oculatus	77.70	0.00e+00	976.00
IUUC-Mcc-055109	Macaca mulatta	96.39	0.00e+00	1234.00
IUUC-Meu-056522	Macropus eugenii	74.37	2.00e-103	370.00
IUUC-Mga-060012	Meleagris gallopavo	81.83	0.00e+00	1063.00
IUUC-Mmr-061364	Microcebus murinus	96.23	0.00e+00	1231.00
IUUC-Mdo-063033	Monodelphis domestica	82.50	0.00e+00	1010.00
IUUC-Mmu-063880	Mus musculus	93.28	0.00e+00	1169.00
IUUC-Mlu-068233	Myotis lucifugus	95.90	0.00e+00	1209.00
IUUC-Opr-070638	Ochotona princeps	94.08	0.00e+00	865.00
IUUC-Ont-071960	Oreochromis niloticus	61.37	0.00e+00	789.00
IUUC-Oan-073406	Ornithorhynchus anatinus	83.11	0.00e+00	1064.00
IUUC-Ocu-074612	Oryctolagus cuniculus	95.39	0.00e+00	1222.00
IUUC-Ola-087181	Oryzias latipes	59.15	0.00e+00	765.00
IUUC-Oga-088955	Otolemur garnettii	96.23	0.00e+00	1232.00
IUUC-Oar-089682	Ovis aries	96.72	0.00e+00	1208.00
IUUC-Ptr-090969	Pan troglodytes	96.23	0.00e+00	1232.00
IUUC-Pan-092289	Papio anubis	96.39	0.00e+00	1234.00
IUUC-Psi-093279	Pelodiscus sinensis	85.25	0.00e+00	1113.00
IUUC-Pab-097957	Pongo abelii	96.93	0.00e+00	932.00
IUUC-Pca-100619	Procavia capensis	95.74	0.00e+00	1235.00
IUUC-Pva-102533	Pteropus vampyrus	94.34	0.00e+00	721.00
IUUC-Rno-106111	Rattus norvegicus	93.44	0.00e+00	1199.00
IUUC-Sha-106716	Sarcophilus harrisii	83.77	0.00e+00	1071.00
IUUC-Tgu-116839	Taeniopygia guttata	83.61	0.00e+00	1092.00
IUUC-Tru-117792	Takifugu rubripes	60.46	0.00e+00	764.00
IUUC-Tsy-119609	Tarsius syrichta	91.10	5.00e-158	550.00
IUUC-Tni-119682	Tetraodon nigroviridis	60.30	0.00e+00	763.00
IUUC-Tme-127039	Tuber melanosporum	30.46	1.00e-11	65.90
IUUC-Tbe-127961	Tupaia belangeri	90.33	0.00e+00	1119.00
IUUC-Ttr-128917	Tursiops truncatus	95.10	0.00e+00	1021.00
IUUC-Vpa-130721	Vicugna pacos	97.64	0.00e+00	867.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence