iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003405

Ensembl Protein ID

ENSAPLP00000012776.1

UniProt Accession

U3IZU9; U3IZU9_ANAPL

Genbank Protein ID

ENSAPLP00000012776

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01125357

Gene Name

BAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000012974.1	ENSAPLT00000013520.1	ENSAPLP00000012776.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.20e-63	215.2	2	514

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 209  teelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid.................................. 259
           +ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr++++ +l++lk++                                  
   Q: 2    DEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRMKYESKLHILKMNrqtvlealqqlirvtqpeliqtqksqesqsteet 88
           89**********..*************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 89   kpassktvapesthpgwkgrgvkndpteevgsnvgrsvgpeqlherqlflrgtgssdfqlskctqefcprgsssspssrqavsggvlqe 177
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 178  eedlaagvgrsrvpvrqhqqysddeddydddeeeevrntnsairykrkgqvkqehaagaadgqlsvlqpntinvlaeklkesqkdlsip 266
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 267  lsiktsssgaavxtaseigsafnsplrspirsanptrpsspvtshiskvlfgeedgllridcmrynravrdlgpiissgllhltedgvf 355
           ***************************************************************************************** PP
   S: 260  ...........................................................keLlkLlkdieseeekieaqlddekekrkk 289
                                                                      keLl+Llk++e+e++++ea+l++e+ekrkk
   Q: 356  cplavadggkssplsikpgeeaqvaikleekegseagdskekvglgrtsdhpggekyspKELLALLKCVEAEIANYEACLKEEVEKRKK 444
           ***************************************************************************************** PP
   S: 290  fkiddirRtenydeficifikdlaregilrklveetisevrefgvnegrlakqrkqgrekkirplkrkrk 359
           fkidd+rRt+nydefic+fi++la+eg+l+ lve++is++r++gv++grl+kqrk++r+k++rp+k+kr+
   Q: 445  FKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ 514
           ********************************************************************97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

XDEEWTDKAR RVIMERIGLA TAGEPYHDIR FNLMAVVPDR RMKYESKLHI LKMNRQTVLE 60
ALQQLIRVTQ PELIQTQKSQ ESQSTEETKP ASSKTVAPES THPGWKGRGV KNDPTEEVGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NATGACGAAG AATGGACAGA CAAAGCCAGG AGGGTGATCA TGGAGCGCAT CGGCCTGGCC 60
ACTGCAGGGT AATGTCCCAG CCCTGCTGCG GGCTCTGGGT CATCTCCTCT GCCCCTGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001578--Peptidase_C12_UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0035517--C:PR-DUB complex
GO:0003682--F:chromatin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0061519--P:macrophage homeostasis
GO:0035522--P:monoubiquitinated histone H2A deubiquitination
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0071108--P:protein K48-linked deubiquitination
GO:0051726--P:regulation of cell cycle
GO:0001558--P:regulation of cell growth
GO:1900015--P:regulation of cytokine production involved in inflammatory response
GO:0010035--P:response to inorganic substance
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	74.86	7.00e-140	490.00
IUUC-Aca-004836	Anolis carolinensis	69.76	0.00e+00	684.00
IUUC-Ame-011946	Astyanax mexicanus	49.13	9.00e-115	407.00
IUUC-Bta-013131	Bos taurus	61.72	5.00e-134	471.00
IUUC-Cja-019599	Callithrix jacchus	68.89	0.00e+00	668.00
IUUC-Cfa-021003	Canis familiaris	67.03	0.00e+00	629.00
IUUC-Cpo-022143	Cavia porcellus	69.61	0.00e+00	658.00
IUUC-Csa-023477	Chlorocebus sabaeus	68.70	0.00e+00	667.00
IUUC-Cho-024734	Choloepus hoffmanni	74.25	2.00e-108	386.00
IUUC-Dre-027793	Danio rerio	52.37	5.00e-124	437.00
IUUC-Dno-029253	Dasypus novemcinctus	69.98	0.00e+00	674.00
IUUC-Dor-030891	Dipodomys ordii	76.04	7.00e-144	504.00
IUUC-Ete-032646	Echinops telfairi	71.39	8.00e-137	480.00
IUUC-Eca-033805	Equus caballus	68.52	0.00e+00	639.00
IUUC-Eeu-035216	Erinaceus europaeus	75.51	1.00e-123	436.00
IUUC-Fca-035611	Felis catus	67.41	4.00e-176	611.00
IUUC-Fal-037186	Ficedula albicollis	80.19	0.00e+00	792.00
IUUC-Gmo-038824	Gadus morhua	77.55	4.00e-57	216.00
IUUC-Gga-040875	Gallus gallus	86.83	3.00e-158	551.00
IUUC-Gac-042226	Gasterosteus aculeatus	54.02	2.00e-132	465.00
IUUC-Ggo-045122	Gorilla gorilla	69.61	0.00e+00	667.00
IUUC-Hsa-045882	Homo sapiens	69.79	0.00e+00	670.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	67.96	0.00e+00	655.00
IUUC-Lch-049960	Latimeria chalumnae	66.36	2.00e-175	608.00
IUUC-Loc-052408	Lepisosteus oculatus	51.96	4.00e-54	205.00
IUUC-Laf-054187	Loxodonta africana	68.67	0.00e+00	638.00
IUUC-Mcc-055273	Macaca mulatta	68.89	0.00e+00	669.00
IUUC-Meu-056267	Macropus eugenii	79.11	9.00e-149	520.00
IUUC-Mga-059958	Meleagris gallopavo	96.08	4.00e-45	174.00
IUUC-Mmr-061280	Microcebus murinus	69.10	0.00e+00	654.00
IUUC-Mdo-062625	Monodelphis domestica	70.73	0.00e+00	694.00
IUUC-Mmu-063853	Mus musculus	67.54	0.00e+00	637.00
IUUC-Mlu-067771	Myotis lucifugus	67.78	0.00e+00	629.00
IUUC-Opr-070741	Ochotona princeps	70.54	0.00e+00	664.00
IUUC-Ont-072172	Oreochromis niloticus	54.72	1.00e-136	479.00
IUUC-Oan-073167	Ornithorhynchus anatinus	67.12	3.00e-177	614.00
IUUC-Ocu-074176	Oryctolagus cuniculus	67.09	0.00e+00	633.00
IUUC-Oga-089153	Otolemur garnettii	67.72	0.00e+00	662.00
IUUC-Oar-090008	Ovis aries	66.42	5.00e-179	620.00
IUUC-Ptr-091234	Pan troglodytes	69.79	0.00e+00	670.00
IUUC-Pan-092005	Papio anubis	68.52	0.00e+00	666.00
IUUC-Psi-093995	Pelodiscus sinensis	71.52	1.00e-58	221.00
IUUC-Pma-094110	Petromyzon marinus	45.39	4.00e-50	192.00
IUUC-Pfo-097418	Poecilia formosa	52.49	4.00e-130	458.00
IUUC-Pab-098267	Pongo abelii	69.42	0.00e+00	644.00
IUUC-Pca-101084	Procavia capensis	64.97	2.00e-160	558.00
IUUC-Pva-102292	Pteropus vampyrus	59.10	8.00e-85	308.00
IUUC-Rno-105251	Rattus norvegicus	68.08	4.00e-180	624.00
IUUC-Sha-107100	Sarcophilus harrisii	70.92	0.00e+00	693.00
IUUC-Sar-113559	Sorex araneus	76.60	2.00e-139	488.00
IUUC-Ssc-115688	Sus scrofa	67.90	0.00e+00	640.00
IUUC-Tgu-117424	Taeniopygia guttata	78.49	0.00e+00	768.00
IUUC-Tru-118585	Takifugu rubripes	53.15	7.00e-132	464.00
IUUC-Tsy-119299	Tarsius syrichta	59.32	3.00e-136	478.00
IUUC-Tni-120808	Tetraodon nigroviridis	53.97	1.00e-130	460.00
IUUC-Tbe-127705	Tupaia belangeri	91.46	3.00e-41	162.00
IUUC-Ttr-128225	Tursiops truncatus	66.85	3.00e-178	618.00
IUUC-Vpa-130193	Vicugna pacos	74.01	9.00e-105	374.00
IUUC-Xtr-132449	Xenopus tropicalis	59.13	9.00e-146	510.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence