iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052408

Ensembl Protein ID

ENSLOCP00000017511.1

UniProt Accession

W5NA52; W5NA52_LEPOC

Genbank Protein ID

ENSLOCP00000017511

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AHAT01015069

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000014219.1	ENSLOCT00000017543.1	ENSLOCP00000017511.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	4.70e-117	391.4	3	270

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           k+wleLesdPglftllvedfgvk++ qvee+y+L++++    q pv+g+++lFk++e+r+s+rk+++++++++v+d++i++ +ffa+q+
   Q: 3    KGWLELESDPGLFTLLVEDFGVKGV-QVEEIYDLQSKC----QSPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDDEIVNDMFFAHQL 86
           89***********************.************....*********************************************** PP
   S: 95   igNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsy 183
           i+NsCat+Allsvllnc+++  dlG tlsr+ke+tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q++ ++++t+eafhfvsy
   Q: 87   IPNSCATHALLSVLLNCNNV--DLGLTLSRMKEFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSY 173
           ******************99..******************************************************************* PP
   S: 184  vningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkidkeLlkLlkd 268
           v+i+grl+eldglk++P+d+g+++e+ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr++++ +l++lk+++  + +l+ 
   Q: 174  VPIKGRLFELDGLKAYPIDHGPWGEEEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRIKYESKLHILKMNR--QTVLEG 258
           *************************************..*****************************************9..566666 PP
   S: 269  ieseeekieaql 280
           ++ ++   +  l
   Q: 259  LQQLIRVTQLDL 270
           666665555544 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MNKGWLELES DPGLFTLLVE DFGVKGVQVE EIYDLQSKCQ SPVYGFIFLF KWIEERRSRR 60
KVSTLVDETS VIDDEIVNDM FFAHQLIPNS CATHALLSVL LNCNNVDLGL TLSRMKEFTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCTCTCGT GTGGTGACGT TTGGGCTGTT CTACGTTTTA GCTTTTGCGC TTTTGGTGGT 60
GTTGTGGCAC TGTAGTCCCT GTTTAATGAC GTCGAGGCAG ACGATTAACT CTCCGTTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	74.10	3.00e-176	611.00
IUUC-Apl-003405	Anas platyrhynchos	93.06	3.00e-35	142.00
IUUC-Aca-004836	Anolis carolinensis	72.94	1.00e-180	626.00
IUUC-Ame-011946	Astyanax mexicanus	78.21	5.00e-175	607.00
IUUC-Bta-013131	Bos taurus	71.09	9.00e-161	560.00
IUUC-Cja-019599	Callithrix jacchus	75.97	0.00e+00	637.00
IUUC-Cfa-021003	Canis familiaris	75.11	5.00e-176	611.00
IUUC-Cpo-022143	Cavia porcellus	75.16	0.00e+00	627.00
IUUC-Csa-023477	Chlorocebus sabaeus	75.54	0.00e+00	634.00
IUUC-Cho-024734	Choloepus hoffmanni	51.89	1.00e-64	240.00
IUUC-Csv-025842	Ciona savignyi	56.38	3.00e-92	332.00
IUUC-Dre-027793	Danio rerio	73.55	0.00e+00	639.00
IUUC-Dno-029253	Dasypus novemcinctus	74.95	3.00e-176	612.00
IUUC-Dor-030891	Dipodomys ordii	66.74	4.00e-155	541.00
IUUC-Dme-031796	Drosophila melanogaster	63.77	5.00e-94	338.00
IUUC-Ete-032646	Echinops telfairi	88.43	2.00e-121	429.00
IUUC-Eca-033805	Equus caballus	75.75	8.00e-180	624.00
IUUC-Eeu-035216	Erinaceus europaeus	65.50	8.00e-70	258.00
IUUC-Fca-035611	Felis catus	73.70	1.00e-168	586.00
IUUC-Fal-037186	Ficedula albicollis	73.44	2.00e-144	506.00
IUUC-Gmo-038824	Gadus morhua	76.29	0.00e+00	649.00
IUUC-Gga-040875	Gallus gallus	78.11	0.00e+00	667.00
IUUC-Gac-042226	Gasterosteus aculeatus	77.23	0.00e+00	635.00
IUUC-Ggo-045122	Gorilla gorilla	75.59	0.00e+00	636.00
IUUC-Hsa-045882	Homo sapiens	75.16	0.00e+00	629.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	76.18	3.00e-178	618.00
IUUC-Lch-049960	Latimeria chalumnae	69.02	5.00e-168	584.00
IUUC-Laf-054187	Loxodonta africana	75.32	0.00e+00	646.00
IUUC-Mcc-055273	Macaca mulatta	73.61	3.00e-174	605.00
IUUC-Meu-056267	Macropus eugenii	70.75	2.00e-175	609.00
IUUC-Mga-059958	Meleagris gallopavo	95.70	2.00e-149	521.00
IUUC-Mmr-061280	Microcebus murinus	75.59	6.00e-179	620.00
IUUC-Mdo-062625	Monodelphis domestica	77.56	0.00e+00	689.00
IUUC-Mmu-063853	Mus musculus	75.54	1.00e-179	623.00
IUUC-Mlu-067771	Myotis lucifugus	75.58	5.00e-180	624.00
IUUC-Opr-070741	Ochotona princeps	76.28	0.00e+00	636.00
IUUC-Ont-072172	Oreochromis niloticus	74.68	0.00e+00	652.00
IUUC-Oan-073167	Ornithorhynchus anatinus	80.51	0.00e+00	645.00
IUUC-Ocu-074176	Oryctolagus cuniculus	75.74	5.00e-177	614.00
IUUC-Ola-087203	Oryzias latipes	83.04	4.00e-138	483.00
IUUC-Oga-089153	Otolemur garnettii	74.67	2.00e-175	609.00
IUUC-Oar-090008	Ovis aries	72.26	9.00e-177	613.00
IUUC-Ptr-091234	Pan troglodytes	75.59	0.00e+00	634.00
IUUC-Pan-092005	Papio anubis	75.32	0.00e+00	634.00
IUUC-Psi-093995	Pelodiscus sinensis	78.65	3.00e-173	602.00
IUUC-Pma-094110	Petromyzon marinus	88.00	9.00e-63	234.00
IUUC-Pfo-097418	Poecilia formosa	72.63	2.00e-178	619.00
IUUC-Pab-098267	Pongo abelii	75.59	0.00e+00	635.00
IUUC-Pca-101084	Procavia capensis	75.54	0.00e+00	664.00
IUUC-Pva-102292	Pteropus vampyrus	74.95	0.00e+00	632.00
IUUC-Rno-105251	Rattus norvegicus	73.49	9.00e-177	613.00
IUUC-Sha-107100	Sarcophilus harrisii	76.03	0.00e+00	656.00
IUUC-Sar-113559	Sorex araneus	92.27	3.00e-115	409.00
IUUC-Ssc-115688	Sus scrofa	74.89	5.00e-176	611.00
IUUC-Tgu-117424	Taeniopygia guttata	75.76	0.00e+00	634.00
IUUC-Tru-118585	Takifugu rubripes	73.88	0.00e+00	630.00
IUUC-Tsy-119299	Tarsius syrichta	63.30	3.00e-139	488.00
IUUC-Tni-120808	Tetraodon nigroviridis	74.30	0.00e+00	631.00
IUUC-Tbe-127705	Tupaia belangeri	78.07	5.00e-151	526.00
IUUC-Ttr-128225	Tursiops truncatus	75.54	7.00e-180	624.00
IUUC-Vpa-130193	Vicugna pacos	73.25	3.00e-93	336.00
IUUC-Xtr-132449	Xenopus tropicalis	68.27	3.00e-161	561.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence