iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.70e-54	183.8	36	170

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++++k+l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g+Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G++Cl+il+  
   Q: 36   RLMRDFKRLQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQ-- 121
           9**********************9.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 122  NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 170
           **********************************************996 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MHLSPRPAEL ETSDGGSEAR LTAGQLRSMS TPARRRLMRD FKRLQEDPPV GVSGAPSENN 60
IMQWNAVIFG PEGTPFEDGT FKLVIEFSEE YPNKPPTVRF LSKMFHPNVY ADGSICLDIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAAGGACCT GCTTTGTGAG ACCTGAAACC AAGAGCCAGG CTAGGCCGTC ACGTGACTTG 60
TTCTGATGGC GTCACAGGCA CACGTGGTTC TAGATACTTC GCTCCCTCCC CCTCAGGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding

KEGG

rno:103694902

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001001	Aegilops tauschii	74.50	8.00e-69	252.00
IUUC-Aml-002120	Ailuropoda melanoleuca	100.00	2.00e-88	317.00
IUUC-Atr-002862	Amborella trichopoda	76.67	7.00e-71	258.00
IUUC-Apl-004063	Anas platyrhynchos	92.62	5.00e-77	279.00
IUUC-Aca-005001	Anolis carolinensis	99.34	2.00e-88	317.00
IUUC-Aly-005584	Arabidopsis lyrata	76.51	4.00e-70	256.00
IUUC-Ath-007149	Arabidopsis thaliana	76.51	4.00e-70	256.00
IUUC-Ago-007745	Ashbya gossypii	69.80	6.00e-63	233.00
IUUC-Acl-008139	Aspergillus clavatus	68.87	5.00e-64	236.00
IUUC-Afl-008551	Aspergillus flavus	68.87	8.00e-64	235.00
IUUC-Afu-008980	Aspergillus fumigatus	68.87	8.00e-64	235.00
IUUC-Ang-009554	Aspergillus niger	68.87	8.00e-64	235.00
IUUC-Aor-010242	Aspergillus oryzae	68.87	8.00e-64	235.00
IUUC-Ate-010390	Aspergillus terreus	68.87	8.00e-64	235.00
IUUC-Ame-010743	Astyanax mexicanus	96.71	4.00e-85	306.00
IUUC-Bgr-012039	Blumeria graminis	66.91	4.00e-56	209.00
IUUC-Bta-012840	Bos taurus	100.00	2.00e-88	317.00
IUUC-Bci-013919	Botrytis cinerea	69.08	8.00e-65	238.00
IUUC-Bdi-015010	Brachypodium distachyon	75.84	1.00e-69	254.00
IUUC-Bol-015726	Brassica oleracea	76.00	1.00e-69	257.00
IUUC-Bra-016809	Brassica rapa	76.16	2.00e-70	258.00
IUUC-Cel-018244	Caenorhabditis elegans	84.56	8.00e-77	279.00
IUUC-Cja-019737	Callithrix jacchus	100.00	2.00e-88	317.00
IUUC-Cfa-020244	Canis familiaris	100.00	2.00e-88	317.00
IUUC-Cpo-022192	Cavia porcellus	100.00	2.00e-88	317.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	75.97	4.00e-58	216.00
IUUC-Csa-023430	Chlorocebus sabaeus	100.00	2.00e-88	317.00
IUUC-Cho-024773	Choloepus hoffmanni	79.61	5.00e-65	239.00
IUUC-Cin-025537	Ciona intestinalis	80.92	7.00e-62	229.00
IUUC-Csv-025846	Ciona savignyi	82.00	5.00e-67	246.00
IUUC-Cgl-026381	Colletotrichum gloeosporioides	68.87	2.00e-64	237.00
IUUC-Cne-026864	Cryptococcus neoformans	69.80	2.00e-64	237.00
IUUC-Cme-027284	Cyanidioschyzon merolae	66.67	2.00e-54	205.00
IUUC-Dno-029661	Dasypus novemcinctus	100.00	2.00e-88	317.00
IUUC-Dor-030452	Dipodomys ordii	100.00	6.00e-79	285.00
IUUC-Dse-031487	Dothistroma septosporum	68.87	4.00e-64	236.00
IUUC-Dme-031863	Drosophila melanogaster	86.09	8.00e-77	278.00
IUUC-Ete-032595	Echinops telfairi	96.71	1.00e-85	308.00
IUUC-Eca-033377	Equus caballus	100.00	2.00e-88	317.00
IUUC-Fca-036336	Felis catus	100.00	2.00e-88	317.00
IUUC-Fox-037808	Fusarium oxysporum	68.87	2.00e-64	237.00
IUUC-Fso-038232	Fusarium solani	68.87	3.00e-64	237.00
IUUC-Ggr-039875	Gaeumannomyces graminis	69.13	1.00e-63	234.00
IUUC-Gga-040494	Gallus gallus	100.00	2.00e-88	317.00
IUUC-Gac-042471	Gasterosteus aculeatus	95.39	1.00e-85	308.00
IUUC-Gma-043865	Glycine max	76.51	1.00e-70	258.00
IUUC-Hsa-046239	Homo sapiens	100.00	2.00e-88	317.00
IUUC-Hvu-047054	Hordeum vulgare	74.50	8.00e-69	252.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	100.00	2.00e-88	317.00
IUUC-Kpa-049225	Komagataella pastoris	69.33	9.00e-63	232.00
IUUC-Lch-050283	Latimeria chalumnae	97.35	5.00e-86	309.00
IUUC-Lpe-051301	Leersia perrieri	76.51	3.00e-70	256.00
IUUC-Loc-051962	Lepisosteus oculatus	98.03	7.00e-87	311.00
IUUC-Laf-053380	Loxodonta africana	100.00	2.00e-88	317.00
IUUC-Mcc-054819	Macaca mulatta	94.89	8.00e-95	338.00
IUUC-Mor-057087	Magnaporthe oryzae	67.16	8.00e-55	205.00
IUUC-Mpo-057498	Magnaporthe poae	62.01	3.00e-64	238.00
IUUC-Mtr-058305	Medicago truncatula	76.51	2.00e-70	257.00
IUUC-Mla-058876	Melampsora laricipopulina	72.85	1.00e-58	218.00
IUUC-Mga-059863	Meleagris gallopavo	98.57	1.00e-79	288.00
IUUC-Mvi-060330	Microbotryum violaceum	72.85	2.00e-58	217.00
IUUC-Mmr-060630	Microcebus murinus	100.00	2.00e-88	317.00
IUUC-Mdo-062676	Monodelphis domestica	100.00	2.00e-88	317.00
IUUC-Mmu-063491	Mus musculus	100.00	2.00e-88	317.00
IUUC-Mac-065428	Musa acuminata	71.43	2.00e-70	258.00
IUUC-Mpu-065803	Mustela putorius furo	100.00	2.00e-88	317.00
IUUC-Mlu-067147	Myotis lucifugus	100.00	2.00e-88	317.00
IUUC-Nfi-068580	Neosartorya fischeri	68.87	8.00e-64	235.00
IUUC-Ncr-068913	Neurospora crassa	68.87	1.00e-64	238.00
IUUC-Nle-070105	Nomascus leucogenys	100.00	2.00e-88	317.00
IUUC-Opr-070935	Ochotona princeps	100.00	2.00e-88	317.00
IUUC-Ont-071335	Oreochromis niloticus	95.39	2.00e-85	307.00
IUUC-Oan-072706	Ornithorhynchus anatinus	94.63	6.00e-81	292.00
IUUC-Ocu-074130	Oryctolagus cuniculus	100.00	2.00e-88	317.00
IUUC-Oba-075896	Oryza barthii	75.84	1.00e-69	254.00
IUUC-Obr-076713	Oryza brachyantha	76.51	3.00e-70	256.00
IUUC-Ogl-077116	Oryza glaberrima	76.51	3.00e-70	256.00
IUUC-Ogu-078696	Oryza glumaepatula	76.51	3.00e-70	256.00
IUUC-Oin-079099	Oryza indica	76.51	3.00e-70	256.00
IUUC-Ome-081285	Oryza meridionalis	76.51	3.00e-70	256.00
IUUC-Oni-082088	Oryza nivara	76.51	3.00e-70	256.00
IUUC-Opu-083310	Oryza punctata	76.51	3.00e-70	256.00
IUUC-Oru-084449	Oryza rufipogon	76.51	3.00e-70	256.00
IUUC-Osa-085923	Oryza sativa	76.51	3.00e-70	256.00
IUUC-Ola-087160	Oryzias latipes	95.39	2.00e-85	307.00
IUUC-Olu-087830	Ostreococcus lucimarinus	78.52	9.00e-62	228.00
IUUC-Oga-088836	Otolemur garnettii	100.00	2.00e-88	317.00
IUUC-Oar-090141	Ovis aries	100.00	2.00e-88	317.00
IUUC-Ptr-091453	Pan troglodytes	100.00	2.00e-88	317.00
IUUC-Pan-092511	Papio anubis	100.00	2.00e-88	317.00
IUUC-Psi-093968	Pelodiscus sinensis	99.34	2.00e-88	317.00
IUUC-Pma-094376	Petromyzon marinus	92.76	2.00e-83	300.00
IUUC-Pno-094935	Phaeosphaeria nodorum	68.87	2.00e-64	237.00
IUUC-Ppa-095689	Physcomitrella patens	76.51	4.00e-61	226.00
IUUC-Pab-098121	Pongo abelii	100.00	2.00e-88	317.00
IUUC-Pop-099517	Populus trichocarpa	76.51	2.00e-70	257.00
IUUC-Ppe-101949	Prunus persica	69.94	1.00e-70	258.00
IUUC-Pgr-103611	Puccinia graminis	72.19	6.00e-59	219.00
IUUC-Ptt-103971	Puccinia triticina	72.88	1.00e-44	171.00
IUUC-Pte-104378	Pyrenophora teres	69.54	8.00e-65	238.00
IUUC-Pyt-104757	Pyrenophora triticirepentis	69.54	8.00e-65	238.00
IUUC-Sce-106283	Saccharomyces cerevisiae	69.80	5.00e-63	233.00
IUUC-Sha-107650	Sarcophilus harrisii	98.68	1.00e-86	311.00
IUUC-Sja-107790	Schizosaccharomyces japonicus	71.81	1.00e-58	218.00
IUUC-Spo-108073	Schizosaccharomyces pombe	71.81	8.00e-59	218.00
IUUC-Ssl-108432	Sclerotinia sclerotiorum	69.08	8.00e-65	238.00
IUUC-Smo-109512	Selaginella moellendorffii	76.51	1.00e-70	258.00
IUUC-Sit-110731	Setaria italica	76.51	3.00e-70	256.00
IUUC-Sly-111506	Solanum lycopersicum	77.18	1.00e-70	258.00
IUUC-Stu-112080	Solanum tuberosum	77.18	1.00e-70	258.00
IUUC-Sar-113429	Sorex araneus	100.00	2.00e-88	317.00
IUUC-Sbi-114289	Sorghum bicolor	76.51	3.00e-70	256.00
IUUC-Sre-115106	Sporisorium reilianum	74.17	4.00e-60	223.00
IUUC-Ssc-115257	Sus scrofa	98.03	2.00e-86	310.00
IUUC-Tgu-116604	Taeniopygia guttata	93.83	4.00e-86	309.00
IUUC-Tru-118576	Takifugu rubripes	94.74	4.00e-84	302.00
IUUC-Tsy-119000	Tarsius syrichta	100.00	2.00e-88	317.00
IUUC-Tni-119745	Tetraodon nigroviridis	94.74	3.00e-84	303.00
IUUC-Tca-121827	Theobroma cacao	76.51	2.00e-70	257.00
IUUC-Tre-122002	Trichoderma reesei	68.87	4.00e-64	236.00
IUUC-Tvi-122331	Trichoderma virens	68.87	4.00e-64	236.00
IUUC-Tae-124461	Triticum aestivum	70.91	6.00e-70	256.00
IUUC-Tur-126866	Triticum urartu	75.17	2.00e-69	254.00
IUUC-Tme-127148	Tuber melanosporum	71.14	1.00e-64	238.00
IUUC-Tbe-127921	Tupaia belangeri	98.03	4.00e-84	303.00
IUUC-Ttr-129121	Tursiops truncatus	100.00	2.00e-88	317.00
IUUC-Uma-129561	Ustilago maydis	74.17	2.00e-60	224.00
IUUC-Vda-129711	Verticillium dahliae	68.87	2.00e-64	237.00
IUUC-Vpa-130570	Vicugna pacos	93.43	6.00e-72	262.00
IUUC-Vvi-131108	Vitis vinifera	77.85	6.00e-71	259.00
IUUC-Xtr-131824	Xenopus tropicalis	98.68	3.00e-87	313.00
IUUC-Xma-133667	Xiphophorus maculatus	95.39	2.00e-85	307.00
IUUC-Yli-134660	Yarrowia lipolytica	66.23	3.00e-63	233.00
IUUC-Zma-135584	Zea mays	71.97	2.00e-69	254.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence