iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Stu-112109

Ensembl Protein ID

PGSC0003DMT400068514

UniProt Accession

M1CJ63; M1CJ63_SOLTU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGSC0003DMG400026648	PGSC0003DMT400068514	PGSC0003DMT400068514

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.70e-171	570.1	480	967

Active Site

Position(s)	Description	Evidence
661	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD Qi ++G + q+kl++ak+++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ va +a+  +
   Q: 480  YDAQISVFGNKLQQKLEEAKAFVVGSGALGCEFLKNLALMGVccgeeGKLTITDDDVIEKSNLSRQFLFRDWNIGQAKSTVAGAAASLI 568
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkt 170
           np +++ea +++ ++++e+++   F ++++vVv+aldn+ ar++++++cl+ ++pl+esgtlG + +++ ii++lte y +s+dpp+k+
   Q: 569  NPRIRIEALQNRASPETESVFddtFWENLSVVVNALDNVNARLYIDQRCLYFQKPLLESGTLGAKCNTQMIIPHLTENYGASRDPPEKQ 657
           *******************99******************************************************************** PP
   S: 171  iPfctlketpnaaehtiewa.............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +P+ct+ ++p +++h+++wa             ++ + l+++++  ++ ++    ++ ++++d+v + l +e+ ++fe++i++a+  f+
   Q: 658  APMCTVHSFPHNIDHCLTWArsefegllektptEVNAYLINPSDYISSMQK-AGDAQARDILDRVLECLDKERCDTFEDCITWARLRFE 745
           ********************************7666666666666666665.677999******************************* PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
            ++   +kql+  f+ d  t+s++pfw+                                                          f +
   Q: 746  DYFADRVKQLTYTFPEDATTSSGAPFWSapkrfprplqfsvddashlqfllaasmlraetfgipipdwvnspqklaeavdkvmvpDFQP 834
           **********************************************************************9998888888777775555 PP
   S: 279  naealqvpekvekdeevvkasap..lylllralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikei 361
            ++ + v +  + ++ +++ +++  +  l+  le+ ++k  +g k++ ++fekddd   ++d+++ +an+ra +++i++ +d+ + k i
   Q: 835  KKDVKIVTDEKATSMSASSIDDAavINELVMQLETCRQKlpSGYKMNPIQFEKDDDTnyHMDFIAGLANMRARNYSIPE-VDKLKAKFI 922
           555444444444444444444446977777778777766447899999*******************************.********* PP
   S: 362  agniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           ag+iipaiat +a+  Gl+++E++Kv++g  k e ++n+f ++a+
   Q: 923  AGRIIPAIATSTAMATGLVCLELYKVLNGghKVEDYRNTFANLAL 967
           *****************************999********99875 PP

Organism

Solanum tuberosum

Protein Sequence
(Fasta)

MLPVKRSSIV EVGGDSDGVS VDPLTKKYKT AAAAAAGGDS STVTMAGAGS ATGDVSANGN 60
ATNGRTGGIS PVDLRNLSDI DEDLHSRQLA VYGRETMRKL FAANVLISGL QGLGAEIAKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCACCCAA AACAACCTTC GACCATTTTT TCGTTATCGT CGATACGAAC CCACACACCT 60
CCACTCTCTC TATCTAAGCT CAAAGCATCT CTCACACAAA CCCTAATCAT CACGCGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

sot:102600735

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	78.44	0.00e+00	1651.00
IUUC-Aml-001311	Ailuropoda melanoleuca	44.16	0.00e+00	886.00
IUUC-Atr-002684	Amborella trichopoda	79.33	0.00e+00	1684.00
IUUC-Apl-004158	Anas platyrhynchos	38.71	0.00e+00	675.00
IUUC-Aca-004620	Anolis carolinensis	43.54	0.00e+00	868.00
IUUC-Ago-007873	Ashbya gossypii	45.78	0.00e+00	845.00
IUUC-Acl-008181	Aspergillus clavatus	44.28	0.00e+00	826.00
IUUC-Afu-009065	Aspergillus fumigatus	45.06	0.00e+00	856.00
IUUC-Ate-010466	Aspergillus terreus	45.45	0.00e+00	869.00
IUUC-Ame-010933	Astyanax mexicanus	43.05	0.00e+00	836.00
IUUC-Bgr-012281	Blumeria graminis	44.67	0.00e+00	824.00
IUUC-Bta-012767	Bos taurus	44.13	0.00e+00	892.00
IUUC-Bci-013721	Botrytis cinerea	45.42	0.00e+00	804.00
IUUC-Cel-018260	Caenorhabditis elegans	39.82	0.00e+00	675.00
IUUC-Cja-019152	Callithrix jacchus	43.92	0.00e+00	893.00
IUUC-Cfa-020622	Canis familiaris	42.75	0.00e+00	843.00
IUUC-Cpo-022526	Cavia porcellus	43.93	0.00e+00	878.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	57.85	0.00e+00	1154.00
IUUC-Csa-023780	Chlorocebus sabaeus	43.84	0.00e+00	888.00
IUUC-Cin-025790	Ciona intestinalis	44.62	0.00e+00	885.00
IUUC-Csv-026084	Ciona savignyi	43.76	0.00e+00	862.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	45.82	0.00e+00	889.00
IUUC-Cne-026960	Cryptococcus neoformans	44.87	0.00e+00	866.00
IUUC-Cme-027290	Cyanidioschyzon merolae	39.26	0.00e+00	686.00
IUUC-Dre-028149	Danio rerio	44.19	0.00e+00	871.00
IUUC-Dno-028884	Dasypus novemcinctus	43.46	0.00e+00	887.00
IUUC-Dor-030229	Dipodomys ordii	42.44	0.00e+00	835.00
IUUC-Dse-031524	Dothistroma septosporum	42.71	0.00e+00	817.00
IUUC-Dme-032045	Drosophila melanogaster	44.26	0.00e+00	843.00
IUUC-Ete-033124	Echinops telfairi	38.85	2.00e-128	452.00
IUUC-Eca-033330	Equus caballus	43.66	0.00e+00	884.00
IUUC-Fca-036255	Felis catus	44.23	0.00e+00	881.00
IUUC-Fal-036848	Ficedula albicollis	38.32	0.00e+00	681.00
IUUC-Fox-038007	Fusarium oxysporum	46.62	8.00e-135	473.00
IUUC-Gmo-039338	Gadus morhua	42.90	0.00e+00	831.00
IUUC-Ggr-039823	Gaeumannomyces graminis	44.63	0.00e+00	881.00
IUUC-Gga-040747	Gallus gallus	38.03	0.00e+00	667.00
IUUC-Gac-041773	Gasterosteus aculeatus	43.68	0.00e+00	838.00
IUUC-Ggo-045336	Gorilla gorilla	43.74	0.00e+00	871.00
IUUC-Hsa-045982	Homo sapiens	43.84	0.00e+00	871.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	43.84	0.00e+00	890.00
IUUC-Kpa-049112	Komagataella pastoris	45.96	0.00e+00	863.00
IUUC-Lch-050371	Latimeria chalumnae	44.64	0.00e+00	880.00
IUUC-Lpe-051299	Leersia perrieri	74.95	0.00e+00	1616.00
IUUC-Loc-052936	Lepisosteus oculatus	44.50	0.00e+00	879.00
IUUC-Lma-053315	Leptosphaeria maculans	45.42	0.00e+00	884.00
IUUC-Mcc-055843	Macaca mulatta	43.74	0.00e+00	890.00
IUUC-Meu-056258	Macropus eugenii	43.46	0.00e+00	875.00
IUUC-Mor-057269	Magnaporthe oryzae	44.68	0.00e+00	858.00
IUUC-Mpo-057435	Magnaporthe poae	45.12	0.00e+00	862.00
IUUC-Mvi-060437	Microbotryum violaceum	42.61	0.00e+00	813.00
IUUC-Mmr-061405	Microcebus murinus	43.01	0.00e+00	850.00
IUUC-Mdo-062032	Monodelphis domestica	42.66	0.00e+00	855.00
IUUC-Mmu-063721	Mus musculus	45.28	0.00e+00	891.00
IUUC-Mac-065505	Musa acuminata	78.64	0.00e+00	1661.00
IUUC-Mpu-066409	Mustela putorius furo	44.13	0.00e+00	895.00
IUUC-Mlu-067217	Myotis lucifugus	43.97	0.00e+00	880.00
IUUC-Nfi-068407	Neosartorya fischeri	45.26	0.00e+00	839.00
IUUC-Ncr-068698	Neurospora crassa	45.37	0.00e+00	862.00
IUUC-Nle-070072	Nomascus leucogenys	41.28	0.00e+00	793.00
IUUC-Opr-070715	Ochotona princeps	35.97	2.00e-157	549.00
IUUC-Ont-071671	Oreochromis niloticus	44.47	0.00e+00	858.00
IUUC-Oan-073268	Ornithorhynchus anatinus	40.37	0.00e+00	633.00
IUUC-Ocu-074544	Oryctolagus cuniculus	43.84	0.00e+00	892.00
IUUC-Oba-075120	Oryza barthii	78.69	0.00e+00	1624.00
IUUC-Ogl-077887	Oryza glaberrima	78.69	0.00e+00	1624.00
IUUC-Ogu-078305	Oryza glumaepatula	75.17	0.00e+00	1610.00
IUUC-Olo-081089	Oryza longistaminata	75.37	0.00e+00	1615.00
IUUC-Opu-083301	Oryza punctata	77.58	0.00e+00	1632.00
IUUC-Oru-084469	Oryza rufipogon	75.37	0.00e+00	1613.00
IUUC-Ola-087002	Oryzias latipes	45.42	0.00e+00	876.00
IUUC-Olu-087687	Ostreococcus lucimarinus	58.64	0.00e+00	1145.00
IUUC-Oga-088594	Otolemur garnettii	44.25	0.00e+00	872.00
IUUC-Oar-090068	Ovis aries	44.28	0.00e+00	891.00
IUUC-Ptr-090609	Pan troglodytes	37.94	0.00e+00	670.00
IUUC-Pan-092114	Papio anubis	43.74	0.00e+00	890.00
IUUC-Psi-093489	Pelodiscus sinensis	37.24	0.00e+00	664.00
IUUC-Pma-094214	Petromyzon marinus	47.37	6.00e-36	142.00
IUUC-Pno-095154	Phaeosphaeria nodorum	44.11	0.00e+00	866.00
IUUC-Ppa-095227	Physcomitrella patens	72.48	0.00e+00	1520.00
IUUC-Pfo-097184	Poecilia formosa	44.47	0.00e+00	866.00
IUUC-Pab-097861	Pongo abelii	43.65	0.00e+00	857.00
IUUC-Pca-100347	Procavia capensis	42.20	0.00e+00	703.00
IUUC-Ppe-102012	Prunus persica	83.30	0.00e+00	1800.00
IUUC-Pva-102584	Pteropus vampyrus	44.22	0.00e+00	918.00
IUUC-Pte-104200	Pyrenophora teres	45.52	0.00e+00	892.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	44.82	0.00e+00	885.00
IUUC-Rno-105462	Rattus norvegicus	43.28	0.00e+00	867.00
IUUC-Sce-106245	Saccharomyces cerevisiae	44.77	0.00e+00	879.00
IUUC-Sha-107142	Sarcophilus harrisii	43.29	0.00e+00	882.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	43.99	0.00e+00	849.00
IUUC-Spo-108034	Schizosaccharomyces pombe	43.26	0.00e+00	843.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	45.44	0.00e+00	828.00
IUUC-Smo-108912	Selaginella moellendorffii	73.14	0.00e+00	1529.00
IUUC-Sly-110914	Solanum lycopersicum	97.70	0.00e+00	2144.00
IUUC-Sar-113737	Sorex araneus	43.99	0.00e+00	882.00
IUUC-Sbi-114089	Sorghum bicolor	79.88	0.00e+00	1651.00
IUUC-Ssc-115777	Sus scrofa	43.92	0.00e+00	888.00
IUUC-Tgu-116565	Taeniopygia guttata	38.32	0.00e+00	677.00
IUUC-Tru-118742	Takifugu rubripes	43.70	0.00e+00	816.00
IUUC-Tsy-119436	Tarsius syrichta	34.61	5.00e-161	560.00
IUUC-Tni-120401	Tetraodon nigroviridis	43.89	0.00e+00	825.00
IUUC-Tre-122009	Trichoderma reesei	46.42	0.00e+00	845.00
IUUC-Tvi-122259	Trichoderma virens	45.59	0.00e+00	823.00
IUUC-Tur-126330	Triticum urartu	78.44	0.00e+00	1652.00
IUUC-Tme-127055	Tuber melanosporum	43.36	0.00e+00	798.00
IUUC-Tbe-127714	Tupaia belangeri	34.14	2.00e-139	489.00
IUUC-Ttr-128331	Tursiops truncatus	44.03	0.00e+00	874.00
IUUC-Vda-129977	Verticillium dahliae	47.60	0.00e+00	821.00
IUUC-Vpa-130716	Vicugna pacos	37.07	0.00e+00	654.00
IUUC-Vvi-131026	Vitis vinifera	84.57	0.00e+00	1823.00
IUUC-Xtr-132026	Xenopus tropicalis	38.51	0.00e+00	651.00
IUUC-Xma-133805	Xiphophorus maculatus	44.08	0.00e+00	843.00
IUUC-Yli-134547	Yarrowia lipolytica	44.56	0.00e+00	864.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence