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Tag Content
iUUCD ID IUUC-Cpo-022391
Ensembl Protein ID ENSCPOP00000015365.1
UniProt Accession H0VXD5; H0VXD5_CAVPO
Genbank Protein ID ENSCPOP00000015365
Protein Name Phosphoinositide phospholipase C
Genbank Nucleotide ID AAKN02039464
Gene Name PLCG1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000025138.1 ENSCPOT00000027832.1 ENSCPOP00000015365.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 4.90e-12 45.6 793 850
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekl 62
           +k  v++l+dy+aq +deLt++k  +++ +  e+q++gW++g  +  gk+ l fP+n+ve++
   Q: 793  FKCAVKALFDYKAQREDELTFTKSAIIQNV--EKQEGGWWRG--DYGGKKQLwFPSNYVEEM 850
           56789************************9..9*********..676666655******985 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
SSPCANGCGP GAPSDAEVLH LCRSLEVGTV MTLFYSKKSQ RPERKTFQVK LETRQITWSR 60
GADKIEGAKT LQRQVLERTR GGRTIQVEPP AQVLPHFCPD RAHCLGMRLA LTFMLQTLRI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-022391|UBD,SH3|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCGTCCCCCT GCGCTAACGG CTGCGGGCCC GGCGCGCCCT CCGACGCCGA GGTGCTGCAC 60
CTCTGCCGCA GCCTCGAGGT GGGCACCGTC ATGACTTTGT TCTACTCCAA GAAGTCTCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-022391|UBD,SH3|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0807--Transducer
Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3
Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005829--C:cytosol
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0019722--P:calcium-mediated signaling
GO:0016477--P:cell migration
GO:0071364--P:cellular response to epidermal growth factor stimulus
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0001701--P:in utero embryonic development
GO:0009395--P:phospholipid catabolic process
GO:0045766--P:positive regulation of angiogenesis
GO:0043536--P:positive regulation of blood vessel endothelial cell migration
GO:0051281--P:positive regulation of release of sequestered calcium ion into cytosol
GO:0050852--P:T cell receptor signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001452 Ailuropoda melanoleuca 91.06 0.00e+00 2383.00
IUUC-Apl-003541 Anas platyrhynchos 66.51 0.00e+00 1625.00
IUUC-Aca-005291 Anolis carolinensis 81.40 0.00e+00 2095.00
IUUC-Ame-011004 Astyanax mexicanus 65.30 0.00e+00 1661.00
IUUC-Bta-012660 Bos taurus 91.78 0.00e+00 2265.00
IUUC-Cja-019206 Callithrix jacchus 91.48 0.00e+00 2384.00
IUUC-Cfa-020257 Canis familiaris 91.87 0.00e+00 2263.00
IUUC-Csa-024170 Chlorocebus sabaeus 89.77 0.00e+00 1709.00
IUUC-Cin-025520 Ciona intestinalis 45.27 0.00e+00 1014.00
IUUC-Dre-027944 Danio rerio 68.08 0.00e+00 1732.00
IUUC-Dno-029440 Dasypus novemcinctus 93.49 0.00e+00 2247.00
IUUC-Dor-031001 Dipodomys ordii 90.41 0.00e+00 2368.00
IUUC-Eca-033809 Equus caballus 92.11 0.00e+00 2276.00
IUUC-Fca-036510 Felis catus 91.13 0.00e+00 2249.00
IUUC-Fal-037541 Ficedula albicollis 85.90 0.00e+00 2038.00
IUUC-Gmo-038630 Gadus morhua 78.19 0.00e+00 1371.00
IUUC-Gga-040142 Gallus gallus 83.81 0.00e+00 2154.00
IUUC-Ggo-045063 Gorilla gorilla 91.87 0.00e+00 2405.00
IUUC-Hsa-046428 Homo sapiens 91.80 0.00e+00 2403.00
IUUC-Itr-048245 Ictidomys tridecemlineatus 91.36 0.00e+00 2336.00
IUUC-Lch-049766 Latimeria chalumnae 76.14 0.00e+00 1835.00
IUUC-Loc-052285 Lepisosteus oculatus 72.92 0.00e+00 1886.00
IUUC-Laf-053365 Loxodonta africana 90.81 0.00e+00 2236.00
IUUC-Mcc-054871 Macaca mulatta 91.38 0.00e+00 2382.00
IUUC-Meu-056724 Macropus eugenii 83.35 0.00e+00 2007.00
IUUC-Mga-059329 Meleagris gallopavo 84.10 0.00e+00 2028.00
IUUC-Mmr-061110 Microcebus murinus 91.02 0.00e+00 2376.00
IUUC-Mdo-062448 Monodelphis domestica 88.06 0.00e+00 2320.00
IUUC-Mmu-063565 Mus musculus 91.20 0.00e+00 2385.00
IUUC-Mpu-066683 Mustela putorius furo 91.41 0.00e+00 2388.00
IUUC-Mlu-067779 Myotis lucifugus 91.04 0.00e+00 2249.00
IUUC-Nle-069219 Nomascus leucogenys 90.51 0.00e+00 1941.00
IUUC-Opr-070766 Ochotona princeps 93.37 0.00e+00 1439.00
IUUC-Ont-072524 Oreochromis niloticus 69.22 0.00e+00 1803.00
IUUC-Oan-073214 Ornithorhynchus anatinus 92.39 6.00e-47 179.00
IUUC-Ocu-074361 Oryctolagus cuniculus 89.65 0.00e+00 2335.00
IUUC-Ola-086820 Oryzias latipes 68.43 0.00e+00 1813.00
IUUC-Oga-088172 Otolemur garnettii 91.87 0.00e+00 2407.00
IUUC-Oar-090306 Ovis aries 88.75 0.00e+00 2183.00
IUUC-Ptr-090682 Pan troglodytes 91.80 0.00e+00 2404.00
IUUC-Pan-092835 Papio anubis 97.71 0.00e+00 1826.00
IUUC-Psi-093344 Pelodiscus sinensis 81.22 0.00e+00 2120.00
IUUC-Pfo-096984 Poecilia formosa 67.43 0.00e+00 1760.00
IUUC-Pab-097871 Pongo abelii 91.44 0.00e+00 2335.00
IUUC-Pca-100772 Procavia capensis 85.84 0.00e+00 2212.00
IUUC-Pva-102790 Pteropus vampyrus 91.79 0.00e+00 2352.00
IUUC-Rno-105974 Rattus norvegicus 91.32 0.00e+00 2396.00
IUUC-Sar-112995 Sorex araneus 89.05 0.00e+00 2276.00
IUUC-Ssc-115360 Sus scrofa 91.32 0.00e+00 2390.00
IUUC-Tgu-116585 Taeniopygia guttata 80.69 0.00e+00 2024.00
IUUC-Tru-117742 Takifugu rubripes 68.95 0.00e+00 1815.00
IUUC-Tsy-119259 Tarsius syrichta 97.86 0.00e+00 858.00
IUUC-Tni-120833 Tetraodon nigroviridis 64.46 0.00e+00 1583.00
IUUC-Tbe-127504 Tupaia belangeri 82.70 0.00e+00 1386.00
IUUC-Ttr-128650 Tursiops truncatus 85.91 0.00e+00 1144.00
IUUC-Xtr-132862 Xenopus tropicalis 72.87 0.00e+00 1844.00
Created Date 25-Jun-2017

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