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Tag Content
iUUCD ID IUUC-Eca-033234
Ensembl Protein ID ENSECAP00000004282.1
UniProt Accession F7BQ20; F7BQ20_HORSE
Protein Name Uncharacterized protein
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSECAG00000004617.1 ENSECAT00000006078.1 ENSECAP00000004282.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 80.93 0.00e+00 1222.00 IUUC-Hsa-045861
E3 activity/RING/RING 66.33 0.00e+00 941.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Equus caballus
Protein Sequence
(Fasta)
MQQEPVSARS PGPPQDSALP HAPTMPPPES LSEGHQPSPS HCPTEQTTEE EFQFLRCQGC 60
QAEAKCPKLL PCLHTLCSGC LEVPGVRCPI CQAPPPPGAD WLALDNVFFE SLQRRLSVYR 120
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Protein Fasta Sequence



>IUUC-Eca-033234|E3,RING|Equus caballus
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Nucleotide Sequence
(Fasta)
ATGCAGCAGG AGCCTGTATC CGCCAGATCT CCGGGGCCCC CTCAGGACTC TGCGCTGCCC 60
CACGCACCCA CCATGCCTCC CCCGGAGTCC CTTTCAGAAG GCCACCAGCC CAGTCCCAGC 120
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Nucleotide Fasta Sequence



>IUUC-Eca-033234|E3,RING|Equus caballus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

KEGG ecb:100062744
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001901 Ailuropoda melanoleuca 79.21 0.00e+00 1219.00
IUUC-Bta-012427 Bos taurus 75.45 0.00e+00 1222.00
IUUC-Cja-019029 Callithrix jacchus 80.52 0.00e+00 1272.00
IUUC-Cfa-021127 Canis familiaris 76.16 0.00e+00 1190.00
IUUC-Cpo-022553 Cavia porcellus 68.43 0.00e+00 1007.00
IUUC-Csa-023187 Chlorocebus sabaeus 78.63 0.00e+00 858.00
IUUC-Cho-024937 Choloepus hoffmanni 70.16 2.00e-102 367.00
IUUC-Dno-029326 Dasypus novemcinctus 75.75 0.00e+00 1142.00
IUUC-Dor-030808 Dipodomys ordii 61.08 0.00e+00 695.00
IUUC-Ete-032746 Echinops telfairi 54.55 8.00e-176 610.00
IUUC-Fca-035648 Felis catus 81.90 0.00e+00 1313.00
IUUC-Ggo-044927 Gorilla gorilla 80.93 0.00e+00 1299.00
IUUC-Hsa-045861 Homo sapiens 80.93 0.00e+00 1297.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 77.87 0.00e+00 1253.00
IUUC-Loc-052276 Lepisosteus oculatus 36.23 6.00e-53 202.00
IUUC-Laf-054059 Loxodonta africana 74.85 0.00e+00 1159.00
IUUC-Meu-056495 Macropus eugenii 54.46 7.00e-105 374.00
IUUC-Mga-059224 Meleagris gallopavo 31.68 7.00e-79 288.00
IUUC-Mmr-061507 Microcebus murinus 75.12 0.00e+00 1172.00
IUUC-Mdo-062196 Monodelphis domestica 46.83 0.00e+00 642.00
IUUC-Mmu-063118 Mus musculus 66.89 0.00e+00 1058.00
IUUC-Mpu-066024 Mustela putorius furo 73.92 0.00e+00 1165.00
IUUC-Mlu-066980 Myotis lucifugus 77.80 0.00e+00 1181.00
IUUC-Nle-069779 Nomascus leucogenys 80.70 0.00e+00 1239.00
IUUC-Ocu-074016 Oryctolagus cuniculus 66.29 0.00e+00 1025.00
IUUC-Oga-089085 Otolemur garnettii 68.59 0.00e+00 1079.00
IUUC-Oar-089980 Ovis aries 73.08 0.00e+00 1159.00
IUUC-Ptr-091681 Pan troglodytes 80.86 0.00e+00 1296.00
IUUC-Pan-091965 Papio anubis 79.46 0.00e+00 1231.00
IUUC-Psi-093577 Pelodiscus sinensis 37.55 8.00e-114 404.00
IUUC-Pab-098215 Pongo abelii 77.56 0.00e+00 665.00
IUUC-Pca-100883 Procavia capensis 72.79 0.00e+00 847.00
IUUC-Pva-102465 Pteropus vampyrus 75.16 0.00e+00 839.00
IUUC-Rno-105120 Rattus norvegicus 66.98 0.00e+00 1101.00
IUUC-Sar-113320 Sorex araneus 62.54 3.00e-88 319.00
IUUC-Ssc-116042 Sus scrofa 78.51 0.00e+00 1256.00
IUUC-Tbe-127880 Tupaia belangeri 64.81 0.00e+00 851.00
Created Date 25-Jun-2017

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