iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000000013.1	ENSONIT00000000016.1	ENSONIP00000000016.1
ENSONIG00000000013.1	ENSONIT00000000017.1	ENSONIP00000000017.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.60e-57	193.6	23	326

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl+N + +C +NS+LQ+ s + e++ell + +         k++  +++ +l++++e++  +  +    r++l++l + +  f+ + q+
   Q: 23   GLSNYCLSCCVNSLLQTFSVTWEIAELLERWDVAGA-----KGDAHNVALHLKRVLEAMRGDLPQPAPHRDFLHCLDQNN--FRLNVQH 104
           9*****************************333333.....56788*************9999999**********9666..999**** PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da E++  +l+ +++++                          ++k     i+dl++++++++++cl+c++++++++ +l+l+l v+++
   Q: 105  DADEVFLSILNFIHQQM--------------------------DNKVLAGEIQDLYKISVETNLQCLKCNSIQTETSYMLSLPLYVKED 167
           *****************..........................67788889************************************99 PP
   S: 180  eetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts. 267
           ++    sl+ c++sf++ +el+g n ++c +c  k  +++ +kl +lP++L+++LkRf  +++++s +k++ +v+fp+++d s+ +++ 
   Q: 168  DN----SLEGCMNSFFEHQELRGINSCFCAHCGTKNPSRQGVKLLSLPRILCMNLKRF--RNSRGSTRKLDCRVSFPETFDFSQSLQHv 250
           96....8***************************************************..88889******************644443 PP
   S: 268  .peekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg....staYvlfYkr 337
            + +  +++++Y L+avvvH G +  GHY+ayv+++++k W++ dDs+V+++++eev+++ g    +taY+l+Y+r
   Q: 251  fSGNFAQNECRYTLYAVVVHCGYAMFGHYTAYVRHRENKcWYYADDSHVQQTTWEEVQRTYGgrqsRTAYMLMYRR 326
           334555669**************************88888*******************888************98 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MSAGICYCFS RLTLVNHLFG MRGLSNYCLS CCVNSLLQTF SVTWEIAELL ERWDVAGAKG 60
DAHNVALHLK RVLEAMRGDL PQPAPHRDFL HCLDQNNFRL NVQHDADEVF LSILNFIHQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGACCCAT GTGTCACCAA TGCTGTGTAG CTAATAAGCG CCGACGTGAT CGCCGGCGTC 60
ATAGTTCCAG CCGGTTTGCG CATGACAGTT TGTGAGTTTC GTTTCCAGCA AAGCGAAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	33.77	4.00e-45	175.00
IUUC-Apl-004006	Anas platyrhynchos	36.48	4.00e-49	188.00
IUUC-Aca-005088	Anolis carolinensis	33.33	4.00e-39	155.00
IUUC-Ame-010606	Astyanax mexicanus	52.24	5.00e-87	314.00
IUUC-Bta-013036	Bos taurus	34.07	5.00e-47	181.00
IUUC-Cja-019052	Callithrix jacchus	34.06	2.00e-41	162.00
IUUC-Cfa-020554	Canis familiaris	34.80	4.00e-46	178.00
IUUC-Cpo-022421	Cavia porcellus	33.94	1.00e-52	200.00
IUUC-Csa-023737	Chlorocebus sabaeus	35.50	3.00e-29	121.00
IUUC-Cho-024807	Choloepus hoffmanni	32.47	7.00e-20	91.70
IUUC-Dre-027408	Danio rerio	44.51	3.00e-73	268.00
IUUC-Dno-029813	Dasypus novemcinctus	28.12	3.00e-27	115.00
IUUC-Dor-030532	Dipodomys ordii	34.05	6.00e-47	181.00
IUUC-Ete-032254	Echinops telfairi	33.12	2.00e-43	169.00
IUUC-Eca-033482	Equus caballus	33.33	3.00e-45	175.00
IUUC-Eeu-034451	Erinaceus europaeus	32.52	9.00e-27	113.00
IUUC-Fca-036313	Felis catus	34.07	7.00e-47	181.00
IUUC-Fal-037216	Ficedula albicollis	36.06	6.00e-50	191.00
IUUC-Gmo-038649	Gadus morhua	54.60	4.00e-88	317.00
IUUC-Gga-041082	Gallus gallus	36.36	6.00e-47	181.00
IUUC-Gac-042439	Gasterosteus aculeatus	69.47	6.00e-134	470.00
IUUC-Ggo-044957	Gorilla gorilla	33.46	2.00e-37	149.00
IUUC-Hsa-046381	Homo sapiens	33.75	4.00e-47	182.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	35.02	3.00e-50	192.00
IUUC-Loc-052688	Lepisosteus oculatus	45.05	2.00e-68	252.00
IUUC-Laf-054109	Loxodonta africana	33.64	3.00e-47	182.00
IUUC-Mcc-054814	Macaca mulatta	33.75	6.00e-47	181.00
IUUC-Meu-056253	Macropus eugenii	31.91	1.00e-32	133.00
IUUC-Mmr-061613	Microcebus murinus	33.65	9.00e-48	184.00
IUUC-Mdo-061890	Monodelphis domestica	34.18	2.00e-41	162.00
IUUC-Mmu-064329	Mus musculus	34.70	2.00e-44	172.00
IUUC-Mpu-066342	Mustela putorius furo	34.05	1.00e-48	186.00
IUUC-Mlu-067010	Myotis lucifugus	34.06	8.00e-45	174.00
IUUC-Nle-069148	Nomascus leucogenys	33.44	3.00e-47	182.00
IUUC-Opr-070988	Ochotona princeps	38.51	3.00e-25	109.00
IUUC-Ocu-074498	Oryctolagus cuniculus	34.38	1.00e-42	167.00
IUUC-Ola-086753	Oryzias latipes	68.08	1.00e-119	422.00
IUUC-Oga-088497	Otolemur garnettii	34.33	3.00e-46	179.00
IUUC-Oar-089505	Ovis aries	34.28	7.00e-46	177.00
IUUC-Ptr-091656	Pan troglodytes	34.38	1.00e-48	187.00
IUUC-Pan-092498	Papio anubis	33.75	6.00e-47	181.00
IUUC-Psi-093409	Pelodiscus sinensis	33.53	1.00e-43	170.00
IUUC-Pfo-096507	Poecilia formosa	64.58	3.00e-124	437.00
IUUC-Pab-097828	Pongo abelii	32.50	4.00e-45	175.00
IUUC-Pca-100299	Procavia capensis	31.75	2.00e-22	99.80
IUUC-Pva-102972	Pteropus vampyrus	33.23	4.00e-44	171.00
IUUC-Rno-105738	Rattus norvegicus	36.19	1.00e-50	193.00
IUUC-Sha-107309	Sarcophilus harrisii	33.67	3.00e-41	162.00
IUUC-Sar-112983	Sorex araneus	31.85	4.00e-32	132.00
IUUC-Ssc-116049	Sus scrofa	34.81	2.00e-48	186.00
IUUC-Tgu-117115	Taeniopygia guttata	35.87	3.00e-48	185.00
IUUC-Tru-118022	Takifugu rubripes	58.52	2.00e-105	375.00
IUUC-Tni-120306	Tetraodon nigroviridis	56.11	6.00e-104	370.00
IUUC-Ttr-128686	Tursiops truncatus	34.38	3.00e-44	172.00
IUUC-Xtr-132032	Xenopus tropicalis	31.99	2.00e-33	136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence