iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096979

Ensembl Protein ID

ENSPFOP00000019947.2

UniProt Accession

A0A087YPJ4; A0A087YPJ4_POEFO

Genbank Protein ID

ENSPFOP00000019947

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AYCK01001106

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000019820.2	ENSPFOT00000019970.2	ENSPFOP00000019947.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.90e-14	52.9	76	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++++++W+++  ++++ +G +P+n+++ ++
   Q: 76   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNHNGEWCEA--QTKNGQGWVPSNYITPVN 133
           68899************************.***********..79999**********997 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MGQQPGKFVG DQRRPSLPAF IKGGKRDSSR HVSQPWNVFD RHEALQRPDF EGQGLSEAAR 60
WNSKENLLAG PSENDPNLFV ALYDFVASGD NTLSITKGEK LRVLGYNHNG EWCEAQTKNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCCCCCTG AAATGGCTTG TTTTGTCTTG TGAAGCGCGG ACGCTCCACT AATGTGTGAC 60
ACGCGAAGAC ATACTGGTGT AACTTTGATC TGCTCAGGTG ACCTGAATCA CCTGTTCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001550	Ailuropoda melanoleuca	70.85	0.00e+00	1121.00
IUUC-Apl-003452	Anas platyrhynchos	86.86	0.00e+00	1011.00
IUUC-Aca-005312	Anolis carolinensis	71.06	0.00e+00	1077.00
IUUC-Ame-011903	Astyanax mexicanus	78.17	0.00e+00	1214.00
IUUC-Bta-012351	Bos taurus	71.02	0.00e+00	1070.00
IUUC-Cja-019491	Callithrix jacchus	65.06	0.00e+00	1264.00
IUUC-Cfa-021256	Canis familiaris	76.18	0.00e+00	1137.00
IUUC-Cpo-022046	Cavia porcellus	75.43	0.00e+00	1131.00
IUUC-Csa-023046	Chlorocebus sabaeus	65.20	0.00e+00	1220.00
IUUC-Dre-028190	Danio rerio	70.43	0.00e+00	1318.00
IUUC-Dno-029853	Dasypus novemcinctus	86.53	0.00e+00	1073.00
IUUC-Dor-030635	Dipodomys ordii	66.43	0.00e+00	975.00
IUUC-Dme-032098	Drosophila melanogaster	74.03	0.00e+00	763.00
IUUC-Eca-033720	Equus caballus	71.26	0.00e+00	1075.00
IUUC-Eeu-035173	Erinaceus europaeus	80.36	0.00e+00	1000.00
IUUC-Fca-035967	Felis catus	86.53	0.00e+00	1069.00
IUUC-Fal-036723	Ficedula albicollis	65.00	0.00e+00	1206.00
IUUC-Gmo-039550	Gadus morhua	81.70	0.00e+00	1224.00
IUUC-Gga-040481	Gallus gallus	86.33	0.00e+00	1011.00
IUUC-Gac-041643	Gasterosteus aculeatus	79.61	0.00e+00	1642.00
IUUC-Ggo-045299	Gorilla gorilla	64.90	0.00e+00	1259.00
IUUC-Hsa-047033	Homo sapiens	89.74	1.00e-37	147.00
IUUC-Itr-047935	Ictidomys tridecemlineatus	85.39	0.00e+00	1042.00
IUUC-Lch-050530	Latimeria chalumnae	65.99	0.00e+00	1278.00
IUUC-Loc-052430	Lepisosteus oculatus	83.74	0.00e+00	991.00
IUUC-Laf-053609	Loxodonta africana	86.53	0.00e+00	1074.00
IUUC-Mcc-055654	Macaca mulatta	65.45	0.00e+00	1280.00
IUUC-Meu-056488	Macropus eugenii	58.55	0.00e+00	1070.00
IUUC-Mga-059270	Meleagris gallopavo	76.63	0.00e+00	1065.00
IUUC-Mmr-060593	Microcebus murinus	73.86	0.00e+00	1071.00
IUUC-Mdo-062227	Monodelphis domestica	85.15	0.00e+00	1065.00
IUUC-Mmu-064002	Mus musculus	64.89	0.00e+00	1290.00
IUUC-Mac-064649	Musa acuminata	32.18	1.00e-21	99.00
IUUC-Mpu-066197	Mustela putorius furo	72.35	0.00e+00	1112.00
IUUC-Mlu-067255	Myotis lucifugus	70.51	0.00e+00	1060.00
IUUC-Nle-069977	Nomascus leucogenys	69.28	0.00e+00	990.00
IUUC-Opr-070327	Ochotona princeps	67.98	0.00e+00	919.00
IUUC-Ont-072307	Oreochromis niloticus	79.66	0.00e+00	1641.00
IUUC-Oan-073100	Ornithorhynchus anatinus	70.70	0.00e+00	1073.00
IUUC-Ocu-074892	Oryctolagus cuniculus	71.76	0.00e+00	979.00
IUUC-Ola-087389	Oryzias latipes	77.74	0.00e+00	1574.00
IUUC-Oga-088145	Otolemur garnettii	87.02	0.00e+00	1014.00
IUUC-Oar-090432	Ovis aries	74.05	0.00e+00	1057.00
IUUC-Ptr-090800	Pan troglodytes	65.45	0.00e+00	1270.00
IUUC-Psi-093078	Pelodiscus sinensis	66.61	0.00e+00	1247.00
IUUC-Pma-094420	Petromyzon marinus	76.53	0.00e+00	865.00
IUUC-Pca-100874	Procavia capensis	93.42	0.00e+00	705.00
IUUC-Pva-102415	Pteropus vampyrus	71.96	0.00e+00	1113.00
IUUC-Rno-105682	Rattus norvegicus	65.25	0.00e+00	1292.00
IUUC-Sha-106711	Sarcophilus harrisii	71.89	0.00e+00	1089.00
IUUC-Ssc-115472	Sus scrofa	75.73	0.00e+00	1121.00
IUUC-Tgu-117037	Taeniopygia guttata	66.04	0.00e+00	1270.00
IUUC-Tru-118324	Takifugu rubripes	70.76	0.00e+00	1436.00
IUUC-Tsy-119216	Tarsius syrichta	89.76	0.00e+00	1022.00
IUUC-Tni-119950	Tetraodon nigroviridis	71.27	0.00e+00	1427.00
IUUC-Ttr-128209	Tursiops truncatus	66.07	0.00e+00	1280.00
IUUC-Xtr-132477	Xenopus tropicalis	64.01	0.00e+00	944.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence