iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053500

UUCD1 version

UUC-LoA-00329

Ensembl Protein ID

ENSLAFP00000008222.3

UniProt Accession

G3T4E3; G3T4E3_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009811.3	ENSLAFT00000009809.3	ENSLAFP00000008222.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.40e-18	66.1	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.90e-10	39.9	132	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++  ++h+++L+a+S++F+  fl+e +e k k++v+++ v+p v+  ++++lY+ ++d+n+
   Q: 34   DCTLKAGDKSLPCHRLILSACSPYFREYFLSEIDEEK-KKEVVLDNVDPAVLDLIIRYLYSASIDLND 100
           9**********************************99.***************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+ilr++ l+dcp+L+ +a++f+++ F
   Q: 132  PGNCLAILRLGLLLDCPRLAISAREFVSDRF 162
           56**************************998 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MDSQRELAEE LRLYQSTLLQ DGLKDLLDEK KFIDCTLKAG DKSLPCHRLI LSACSPYFRE 60
YFLSEIDEEK KKEVVLDNVD PAVLDLIIRY LYSASIDLND GNVQDIFALA SRFQIPSVFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTCCC AGCGGGAACT CGCAGAGGAA CTGCGGCTTT ACCAGTCCAC CCTTCTTCAG 60
GATGGTCTAA AAGATCTCCT GGATGAGAAG AAATTCATCG ATTGCACCCT AAAAGCAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

KEGG

lav:100668980

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	96.37	0.00e+00	1171.00
IUUC-Apl-003866	Anas platyrhynchos	85.97	0.00e+00	1036.00
IUUC-Aca-005275	Anolis carolinensis	50.88	1.00e-178	619.00
IUUC-Ame-011172	Astyanax mexicanus	62.35	0.00e+00	758.00
IUUC-Bta-012925	Bos taurus	96.37	0.00e+00	1172.00
IUUC-Bdi-014115	Brachypodium distachyon	24.68	8.00e-12	64.70
IUUC-Cja-019348	Callithrix jacchus	96.70	0.00e+00	1177.00
IUUC-Cfa-020782	Canis familiaris	97.19	0.00e+00	1179.00
IUUC-Cpo-021825	Cavia porcellus	94.06	0.00e+00	1145.00
IUUC-Cre-022652	Chlamydomonas reinhardtii	27.17	5.00e-08	51.20
IUUC-Csa-023184	Chlorocebus sabaeus	96.35	0.00e+00	1007.00
IUUC-Cin-025237	Ciona intestinalis	28.99	4.00e-69	255.00
IUUC-Dre-028278	Danio rerio	60.26	0.00e+00	772.00
IUUC-Dno-029516	Dasypus novemcinctus	96.04	0.00e+00	1175.00
IUUC-Dor-030850	Dipodomys ordii	93.40	0.00e+00	759.00
IUUC-Ete-032697	Echinops telfairi	95.05	0.00e+00	1136.00
IUUC-Eca-033714	Equus caballus	96.86	0.00e+00	1178.00
IUUC-Eeu-035245	Erinaceus europaeus	95.08	0.00e+00	1070.00
IUUC-Fal-037632	Ficedula albicollis	55.90	0.00e+00	677.00
IUUC-Gmo-039392	Gadus morhua	57.47	0.00e+00	728.00
IUUC-Ggr-040041	Gaeumannomyces graminis	27.78	1.00e-07	50.40
IUUC-Gga-041106	Gallus gallus	85.48	0.00e+00	1050.00
IUUC-Gac-042252	Gasterosteus aculeatus	60.70	0.00e+00	769.00
IUUC-Ggo-044817	Gorilla gorilla	96.53	0.00e+00	1174.00
IUUC-Hsa-046620	Homo sapiens	96.53	0.00e+00	1174.00
IUUC-Lch-050477	Latimeria chalumnae	69.80	0.00e+00	856.00
IUUC-Loc-051955	Lepisosteus oculatus	70.46	0.00e+00	910.00
IUUC-Mcc-055316	Macaca mulatta	96.37	0.00e+00	1175.00
IUUC-Meu-055972	Macropus eugenii	52.68	0.00e+00	654.00
IUUC-Mor-057181	Magnaporthe oryzae	25.75	3.00e-10	59.30
IUUC-Mga-059451	Meleagris gallopavo	56.54	0.00e+00	706.00
IUUC-Mmr-061444	Microcebus murinus	97.03	0.00e+00	1179.00
IUUC-Mmu-064147	Mus musculus	95.54	0.00e+00	1165.00
IUUC-Mlu-067481	Myotis lucifugus	94.22	0.00e+00	1150.00
IUUC-Ncr-068938	Neurospora crassa	30.10	1.00e-07	51.60
IUUC-Nle-069339	Nomascus leucogenys	96.70	0.00e+00	1177.00
IUUC-Opr-070703	Ochotona princeps	95.87	0.00e+00	1123.00
IUUC-Ont-072420	Oreochromis niloticus	59.80	0.00e+00	788.00
IUUC-Oan-073476	Ornithorhynchus anatinus	93.23	0.00e+00	1140.00
IUUC-Ocu-074248	Oryctolagus cuniculus	96.70	0.00e+00	1182.00
IUUC-Ola-086361	Oryzias latipes	61.67	0.00e+00	777.00
IUUC-Oar-090349	Ovis aries	95.87	0.00e+00	1168.00
IUUC-Pan-092069	Papio anubis	96.53	0.00e+00	1176.00
IUUC-Psi-093671	Pelodiscus sinensis	88.12	0.00e+00	1049.00
IUUC-Pma-094586	Petromyzon marinus	56.07	2.00e-92	332.00
IUUC-Pfo-096122	Poecilia formosa	62.46	0.00e+00	807.00
IUUC-Pab-098711	Pongo abelii	96.37	0.00e+00	1174.00
IUUC-Pca-100495	Procavia capensis	90.59	0.00e+00	1073.00
IUUC-Pva-102401	Pteropus vampyrus	96.70	0.00e+00	1174.00
IUUC-Rno-105969	Rattus norvegicus	95.38	0.00e+00	1162.00
IUUC-Sha-107091	Sarcophilus harrisii	52.31	0.00e+00	673.00
IUUC-Sar-113405	Sorex araneus	93.23	0.00e+00	1122.00
IUUC-Tgu-116725	Taeniopygia guttata	85.81	0.00e+00	1071.00
IUUC-Tru-117743	Takifugu rubripes	59.37	0.00e+00	762.00
IUUC-Tsy-119225	Tarsius syrichta	90.10	0.00e+00	1077.00
IUUC-Tni-120547	Tetraodon nigroviridis	61.63	0.00e+00	784.00
IUUC-Ttr-128645	Tursiops truncatus	96.53	0.00e+00	1174.00
IUUC-Vpa-130714	Vicugna pacos	97.19	0.00e+00	1181.00
IUUC-Xtr-132144	Xenopus tropicalis	76.57	0.00e+00	942.00
IUUC-Xma-133860	Xiphophorus maculatus	62.62	0.00e+00	808.00
IUUC-Yli-134535	Yarrowia lipolytica	23.53	1.00e-06	47.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence