iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070115

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01181344

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000016183.2	ENSNLET00000020624.2	ENSNLEP00000019634.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-34	116.8	201	231
UBD/Beta-Prp	1.40e-56	191.9	24	245

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++++++++ +d t+l+s+s+D+t k+WD+
   Q: 201  HDGGIYAISWsPDsTHLLSASGDKTSKIWDV 231
           99*********999****************7 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++g
   Q: 24   EHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITG 112
           455566668*************************998777742334567***********99999999887777777789********* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +s+ ++l++Gs+d+ +  ++ +  +    t   h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l  +++
   Q: 113  HNKVINSVDIKQSRpYRLATGSDDNCAAFFEGPPFKFKF-TIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALggSKA 200
           ************999*****************9999998.99********************************************888 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
           h++ +y +s+++++++l+s+s d+t k+wd+  +++v t+   ++
   Q: 201  HDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGST 245
           ************************************999976544 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

LLLHSFCSFR GLLQNPALAD IYTEHAHQVV VAKYAPSGFY IASGDVSGKL RIWDTTQKEH 60
LLKYEYQPFA GKIKDIAWTE DSKRIAVVGE GREKFGAVFL WDSGSSVGEI TGHNKVINSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCTTCTCC ATTCCTTCTG TTCATTCCGG GGTCTTCTGC AGAACCCAGC CCTTGCTGAC 60
ATCTACACGG AGCACGCCCA TCAGGTGGTG GTGGCCAAGT ATGCGCCCAG CGGATTCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043297--P:apical junction assembly
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0030834--P:regulation of actin filament depolymerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	34.86	3.00e-78	285.00
IUUC-Aml-002368	Ailuropoda melanoleuca	93.85	0.00e+00	1076.00
IUUC-Atr-003160	Amborella trichopoda	36.18	1.00e-100	360.00
IUUC-Apl-004012	Anas platyrhynchos	85.20	0.00e+00	958.00
IUUC-Aca-004707	Anolis carolinensis	79.65	0.00e+00	941.00
IUUC-Aly-006465	Arabidopsis lyrata	36.17	7.00e-95	341.00
IUUC-Ath-006740	Arabidopsis thaliana	35.83	6.00e-95	341.00
IUUC-Ago-007920	Ashbya gossypii	28.97	1.00e-64	241.00
IUUC-Acl-008262	Aspergillus clavatus	35.33	2.00e-92	333.00
IUUC-Afl-008471	Aspergillus flavus	29.17	4.00e-62	232.00
IUUC-Afu-008989	Aspergillus fumigatus	37.34	1.00e-92	333.00
IUUC-Ani-009167	Aspergillus nidulans	37.98	7.00e-104	371.00
IUUC-Ang-009595	Aspergillus niger	36.79	3.00e-92	332.00
IUUC-Aor-009908	Aspergillus oryzae	36.05	8.00e-96	344.00
IUUC-Ate-010580	Aspergillus terreus	37.61	2.00e-97	351.00
IUUC-Ame-011269	Astyanax mexicanus	55.31	3.00e-103	369.00
IUUC-Bgr-011996	Blumeria graminis	33.91	2.00e-92	333.00
IUUC-Bta-013278	Bos taurus	92.62	0.00e+00	1090.00
IUUC-Bci-013925	Botrytis cinerea	35.20	6.00e-93	334.00
IUUC-Bdi-014659	Brachypodium distachyon	35.27	4.00e-90	325.00
IUUC-Bol-016043	Brassica oleracea	34.64	9.00e-94	337.00
IUUC-Bra-017139	Brassica rapa	35.65	2.00e-94	339.00
IUUC-Cel-018417	Caenorhabditis elegans	41.06	4.00e-110	391.00
IUUC-Cja-019952	Callithrix jacchus	94.55	0.00e+00	1054.00
IUUC-Cfa-020225	Canis familiaris	92.70	0.00e+00	1075.00
IUUC-Cpo-021900	Cavia porcellus	91.56	0.00e+00	1066.00
IUUC-Csa-023028	Chlorocebus sabaeus	95.96	0.00e+00	1066.00
IUUC-Cho-025030	Choloepus hoffmanni	66.85	0.00e+00	680.00
IUUC-Cin-025152	Ciona intestinalis	55.40	4.00e-65	241.00
IUUC-Csv-025986	Ciona savignyi	37.34	2.00e-89	322.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	37.91	6.00e-98	351.00
IUUC-Cne-026814	Cryptococcus neoformans	33.74	2.00e-83	303.00
IUUC-Dre-027498	Danio rerio	80.79	5.00e-73	266.00
IUUC-Dno-029383	Dasypus novemcinctus	91.92	0.00e+00	1030.00
IUUC-Dor-030633	Dipodomys ordii	95.01	0.00e+00	1107.00
IUUC-Dse-031526	Dothistroma septosporum	38.13	8.00e-105	374.00
IUUC-Dme-031597	Drosophila melanogaster	46.29	2.00e-146	512.00
IUUC-Ete-032780	Echinops telfairi	86.32	0.00e+00	993.00
IUUC-Eca-034306	Equus caballus	94.02	0.00e+00	1085.00
IUUC-Eeu-034531	Erinaceus europaeus	76.71	2.00e-141	496.00
IUUC-Fca-036301	Felis catus	93.57	0.00e+00	1105.00
IUUC-Fal-037361	Ficedula albicollis	83.83	0.00e+00	1020.00
IUUC-Fox-037924	Fusarium oxysporum	35.13	9.00e-89	320.00
IUUC-Fso-038199	Fusarium solani	34.55	2.00e-86	313.00
IUUC-Gmo-039238	Gadus morhua	69.68	0.00e+00	795.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.02	1.00e-82	300.00
IUUC-Gga-040235	Gallus gallus	85.79	0.00e+00	985.00
IUUC-Gac-042363	Gasterosteus aculeatus	68.42	0.00e+00	816.00
IUUC-Gma-044189	Glycine max	35.68	6.00e-99	354.00
IUUC-Ggo-044632	Gorilla gorilla	97.89	0.00e+00	1101.00
IUUC-Hsa-045792	Homo sapiens	95.61	0.00e+00	1090.00
IUUC-Hvu-047517	Hordeum vulgare	35.38	3.00e-96	345.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	92.52	0.00e+00	1071.00
IUUC-Kpa-049183	Komagataella pastoris	32.57	2.00e-76	279.00
IUUC-Lch-050428	Latimeria chalumnae	72.29	0.00e+00	894.00
IUUC-Lpe-051306	Leersia perrieri	35.10	4.00e-96	345.00
IUUC-Loc-052096	Lepisosteus oculatus	68.59	0.00e+00	791.00
IUUC-Lma-053313	Leptosphaeria maculans	39.13	2.00e-103	372.00
IUUC-Laf-054060	Loxodonta africana	89.74	0.00e+00	1036.00
IUUC-Mcc-055619	Macaca mulatta	97.37	0.00e+00	1091.00
IUUC-Meu-056689	Macropus eugenii	74.79	6.00e-158	550.00
IUUC-Mor-056940	Magnaporthe oryzae	34.32	6.00e-84	305.00
IUUC-Mpo-057557	Magnaporthe poae	27.71	3.00e-44	172.00
IUUC-Mtr-057922	Medicago truncatula	35.71	6.00e-98	351.00
IUUC-Mla-059103	Melampsora laricipopulina	33.65	4.00e-71	262.00
IUUC-Mga-060150	Meleagris gallopavo	86.15	0.00e+00	985.00
IUUC-Mvi-060448	Microbotryum violaceum	30.62	2.00e-67	250.00
IUUC-Mmr-061226	Microcebus murinus	92.97	0.00e+00	1068.00
IUUC-Mdo-062674	Monodelphis domestica	88.35	0.00e+00	1032.00
IUUC-Mmu-064170	Mus musculus	92.27	0.00e+00	1068.00
IUUC-Mac-065124	Musa acuminata	36.71	1.00e-99	357.00
IUUC-Mpu-066001	Mustela putorius furo	90.20	0.00e+00	1056.00
IUUC-Mlu-067253	Myotis lucifugus	91.99	0.00e+00	1090.00
IUUC-Nfi-068550	Neosartorya fischeri	37.31	3.00e-97	349.00
IUUC-Ncr-068948	Neurospora crassa	36.19	6.00e-100	358.00
IUUC-Opr-070254	Ochotona princeps	93.32	0.00e+00	1046.00
IUUC-Ont-071666	Oreochromis niloticus	71.48	0.00e+00	843.00
IUUC-Oan-073594	Ornithorhynchus anatinus	88.92	8.00e-160	556.00
IUUC-Ocu-074824	Oryctolagus cuniculus	91.39	0.00e+00	1019.00
IUUC-Oba-075010	Oryza barthii	35.16	3.00e-96	345.00
IUUC-Obr-076364	Oryza brachyantha	35.67	8.00e-97	347.00
IUUC-Ogl-077019	Oryza glaberrima	35.16	3.00e-96	345.00
IUUC-Ogu-078496	Oryza glumaepatula	35.16	3.00e-96	345.00
IUUC-Oin-080116	Oryza indica	35.33	1.00e-96	347.00
IUUC-Olo-080290	Oryza longistaminata	35.16	6.00e-96	344.00
IUUC-Ome-081969	Oryza meridionalis	35.16	4.00e-96	345.00
IUUC-Oni-082075	Oryza nivara	35.16	3.00e-96	345.00
IUUC-Opu-083959	Oryza punctata	35.21	3.00e-96	345.00
IUUC-Oru-084711	Oryza rufipogon	35.16	3.00e-96	345.00
IUUC-Osa-085958	Oryza sativa	35.33	1.00e-96	347.00
IUUC-Ola-086968	Oryzias latipes	72.52	0.00e+00	857.00
IUUC-Oga-089108	Otolemur garnettii	91.74	0.00e+00	1099.00
IUUC-Oar-089986	Ovis aries	87.85	0.00e+00	1007.00
IUUC-Ptr-091281	Pan troglodytes	95.13	0.00e+00	1094.00
IUUC-Pan-092585	Papio anubis	96.13	0.00e+00	1068.00
IUUC-Psi-093811	Pelodiscus sinensis	84.01	0.00e+00	1005.00
IUUC-Pma-094542	Petromyzon marinus	67.31	0.00e+00	796.00
IUUC-Pno-095086	Phaeosphaeria nodorum	37.12	1.00e-96	347.00
IUUC-Ppa-095876	Physcomitrella patens	35.40	4.00e-97	348.00
IUUC-Pfo-096973	Poecilia formosa	72.29	0.00e+00	875.00
IUUC-Pab-098391	Pongo abelii	96.13	0.00e+00	1070.00
IUUC-Pop-098850	Populus trichocarpa	35.65	1.00e-97	350.00
IUUC-Pca-100257	Procavia capensis	63.64	8.00e-100	357.00
IUUC-Ppe-101578	Prunus persica	37.57	2.00e-101	362.00
IUUC-Pva-102872	Pteropus vampyrus	89.46	0.00e+00	1055.00
IUUC-Pgr-103593	Puccinia graminis	33.63	2.00e-73	270.00
IUUC-Pte-104365	Pyrenophora teres	38.86	1.00e-99	357.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.69	8.00e-103	367.00
IUUC-Rno-105737	Rattus norvegicus	92.00	0.00e+00	1098.00
IUUC-Sce-106383	Saccharomyces cerevisiae	29.13	1.00e-59	224.00
IUUC-Sha-107084	Sarcophilus harrisii	88.59	0.00e+00	989.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.01	2.00e-98	353.00
IUUC-Spo-108309	Schizosaccharomyces pombe	34.40	1.00e-86	313.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	34.85	1.00e-92	333.00
IUUC-Smo-109255	Selaginella moellendorffii	33.97	3.00e-86	312.00
IUUC-Sit-109962	Setaria italica	36.30	8.00e-99	354.00
IUUC-Sly-110897	Solanum lycopersicum	36.86	1.00e-101	363.00
IUUC-Stu-111971	Solanum tuberosum	36.52	7.00e-100	357.00
IUUC-Sar-113415	Sorex araneus	72.69	9.00e-110	390.00
IUUC-Sbi-114857	Sorghum bicolor	36.35	7.00e-97	347.00
IUUC-Sre-114900	Sporisorium reilianum	33.57	1.00e-81	297.00
IUUC-Tgu-117256	Taeniopygia guttata	84.72	0.00e+00	1011.00
IUUC-Tru-117871	Takifugu rubripes	67.14	0.00e+00	786.00
IUUC-Tsy-119172	Tarsius syrichta	97.08	4.00e-140	491.00
IUUC-Tni-120339	Tetraodon nigroviridis	67.32	0.00e+00	821.00
IUUC-Tca-121609	Theobroma cacao	35.63	1.00e-97	350.00
IUUC-Tre-122076	Trichoderma reesei	35.24	5.00e-83	301.00
IUUC-Tvi-122528	Trichoderma virens	33.51	4.00e-84	305.00
IUUC-Tae-123530	Triticum aestivum	35.26	2.00e-96	346.00
IUUC-Tur-126845	Triticum urartu	34.83	2.00e-77	283.00
IUUC-Tme-127217	Tuber melanosporum	34.59	2.00e-91	329.00
IUUC-Tbe-127526	Tupaia belangeri	93.85	0.00e+00	1098.00
IUUC-Ttr-128898	Tursiops truncatus	93.40	0.00e+00	1038.00
IUUC-Uma-129631	Ustilago maydis	32.75	3.00e-85	309.00
IUUC-Vda-129732	Verticillium dahliae	35.40	7.00e-83	301.00
IUUC-Vvi-131217	Vitis vinifera	36.87	1.00e-98	353.00
IUUC-Xtr-132860	Xenopus tropicalis	72.25	0.00e+00	847.00
IUUC-Xma-133830	Xiphophorus maculatus	72.65	0.00e+00	879.00
IUUC-Yli-134335	Yarrowia lipolytica	31.58	1.00e-65	243.00
IUUC-Zma-135907	Zea mays	36.35	2.00e-97	350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence