iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000016757.2	ENSCJAT00000032582.1	ENSCJAP00000030831.1
ENSCJAG00000016757.2	ENSCJAT00000032584.2	ENSCJAP00000030833.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.40e-08	34.2	16	57
E3 activity/RING/U-box	4.30e-06	27.7	12	71

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           CaiCl+ f d p+ ++CgH f+++C+  +w     +  +   CP Cr
   Q: 16   CAICLDYFTD-PVMTDCGHNFCRECIrRCW----GQPEGPYACPECR 57
           **********.999************99**....66789999****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl..asggk..tcPvtrqplteedlvPnltl 61
           ee  C+I l+ ++dPv++ +G+ + r++I+++    +      cP +r+   +++l Pn  l
   Q: 12   EEATCAICLDYFTDPVMTDCGHNFCRECIRRCWgqPE--GpyACPECRELSPQRNLRPNRPL 71
           7889***************************995333..346*****************866 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAAPDLSTNL QEEATCAICL DYFTDPVMTD CGHNFCRECI RRCWGQPEGP YACPECRELS 60
PQRNLRPNRP LAKMAEMARR LHPPSPVPQG VCPAHREPLA AFCGDELRLL CAACERSGEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGCCC CCGACCTGTC CACCAACCTC CAGGAGGAGG CCACCTGCGC CATCTGCCTT 60
GACTACTTCA CGGACCCGGT GATGACCGAC TGCGGTCACA ACTTCTGCCG CGAGTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0050768--P:negative regulation of neurogenesis
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0046598--P:positive regulation of viral entry into host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001800	Ailuropoda melanoleuca	62.31	7.00e-128	450.00
IUUC-Bta-012332	Bos taurus	79.70	0.00e+00	651.00
IUUC-Cfa-020491	Canis familiaris	80.13	0.00e+00	661.00
IUUC-Cpo-021936	Cavia porcellus	77.99	0.00e+00	642.00
IUUC-Csa-024151	Chlorocebus sabaeus	84.40	0.00e+00	680.00
IUUC-Cho-024990	Choloepus hoffmanni	78.32	1.00e-114	405.00
IUUC-Dno-029580	Dasypus novemcinctus	68.43	4.00e-149	521.00
IUUC-Dor-030303	Dipodomys ordii	92.65	2.00e-73	268.00
IUUC-Ete-032556	Echinops telfairi	70.56	5.00e-113	400.00
IUUC-Eca-033612	Equus caballus	62.05	6.00e-95	340.00
IUUC-Fca-035821	Felis catus	72.81	2.00e-108	385.00
IUUC-Ggo-044629	Gorilla gorilla	84.40	0.00e+00	681.00
IUUC-Hsa-046332	Homo sapiens	84.40	0.00e+00	680.00
IUUC-Itr-047946	Ictidomys tridecemlineatus	81.41	0.00e+00	649.00
IUUC-Laf-054350	Loxodonta africana	64.08	8.00e-110	390.00
IUUC-Mcc-055827	Macaca mulatta	82.69	0.00e+00	662.00
IUUC-Meu-056122	Macropus eugenii	63.11	2.00e-154	538.00
IUUC-Mmr-061700	Microcebus murinus	80.73	0.00e+00	665.00
IUUC-Mdo-062921	Monodelphis domestica	54.70	2.00e-130	458.00
IUUC-Mmu-063762	Mus musculus	77.78	3.00e-177	614.00
IUUC-Mpu-065873	Mustela putorius furo	79.49	0.00e+00	660.00
IUUC-Mlu-067379	Myotis lucifugus	58.91	6.00e-131	461.00
IUUC-Nle-069440	Nomascus leucogenys	83.90	0.00e+00	676.00
IUUC-Opr-070901	Ochotona princeps	72.18	2.00e-145	508.00
IUUC-Ocu-074038	Oryctolagus cuniculus	62.61	4.00e-124	438.00
IUUC-Oga-088948	Otolemur garnettii	76.97	0.00e+00	634.00
IUUC-Oar-090242	Ovis aries	73.43	2.00e-173	602.00
IUUC-Ptr-090615	Pan troglodytes	94.89	2.00e-98	352.00
IUUC-Pan-092626	Papio anubis	84.40	0.00e+00	681.00
IUUC-Pab-097895	Pongo abelii	77.56	0.00e+00	682.00
IUUC-Pca-100435	Procavia capensis	77.94	0.00e+00	629.00
IUUC-Pva-102288	Pteropus vampyrus	70.73	7.00e-156	543.00
IUUC-Pgr-103696	Puccinia graminis	34.78	3.00e-06	45.40
IUUC-Rno-105938	Rattus norvegicus	77.99	7.00e-179	619.00
IUUC-Sha-107354	Sarcophilus harrisii	66.09	3.00e-158	551.00
IUUC-Smo-108838	Selaginella moellendorffii	44.68	1.00e-07	52.80
IUUC-Tbe-127733	Tupaia belangeri	82.58	0.00e+00	652.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence