iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003307

Ensembl Protein ID

ENSAPLP00000014862.1

UniProt Accession

U3J5T5; U3J5T5_ANAPL

Genbank Protein ID

ENSAPLP00000014862

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

ADON01143892

Gene Name

BLK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000014958.1	ENSAPLT00000015648.1	ENSAPLP00000014862.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-15	57.0	5	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++lyd+ a++d +L+l kG++++v+   +++++W+ +++  +gk+G +P+nFv++++
   Q: 5    IVIALYDFAASSDRDLELVKGEKLQVL---SNEGEWWLAKSLSTGKKGYIPSNFVAQVD 60
           689************************...99************************997 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LENVIVIALY DFAASSDRDL ELVKGEKLQV LSNEGEWWLA KSLSTGKKGY IPSNFVAQVD 60
SLEEEKWYFK TLSRKDAERL LLSSGNKVGS FLVRESETSK GAYSLSVRDS DSAHGDIIKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGAAAACG TCATTGTGAT TGCGCTGTAC GACTTTGCTG CCTCAAGTGA CCGGGACCTG 60
GAGCTGGTCA AGGGGGAGAA ACTCCAAGTC CTCTCCAAGT AAGGGAGCTG CTAGAAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0050853--P:B cell receptor signaling pathway
GO:0032024--P:positive regulation of insulin secretion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	75.89	0.00e+00	741.00
IUUC-Aca-004357	Anolis carolinensis	76.98	0.00e+00	731.00
IUUC-Ame-010642	Astyanax mexicanus	71.85	0.00e+00	696.00
IUUC-Bta-012400	Bos taurus	76.12	0.00e+00	741.00
IUUC-Cfa-021056	Canis familiaris	75.67	0.00e+00	738.00
IUUC-Cpo-021779	Cavia porcellus	76.79	0.00e+00	748.00
IUUC-Csa-023557	Chlorocebus sabaeus	76.63	0.00e+00	742.00
IUUC-Dre-027517	Danio rerio	72.75	0.00e+00	712.00
IUUC-Eca-034218	Equus caballus	76.12	0.00e+00	743.00
IUUC-Eeu-035095	Erinaceus europaeus	56.92	4.00e-149	521.00
IUUC-Fca-036015	Felis catus	74.11	0.00e+00	721.00
IUUC-Fal-036946	Ficedula albicollis	93.27	0.00e+00	878.00
IUUC-Gga-040822	Gallus gallus	94.41	0.00e+00	888.00
IUUC-Ggo-044608	Gorilla gorilla	75.24	0.00e+00	697.00
IUUC-Hsa-046719	Homo sapiens	75.51	0.00e+00	731.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	75.73	0.00e+00	731.00
IUUC-Lch-050114	Latimeria chalumnae	75.45	0.00e+00	734.00
IUUC-Loc-052326	Lepisosteus oculatus	75.23	0.00e+00	723.00
IUUC-Laf-053387	Loxodonta africana	74.33	0.00e+00	723.00
IUUC-Mcc-055026	Macaca mulatta	76.85	0.00e+00	744.00
IUUC-Mga-059427	Meleagris gallopavo	93.53	0.00e+00	879.00
IUUC-Mmr-061660	Microcebus murinus	76.85	0.00e+00	746.00
IUUC-Mdo-062318	Monodelphis domestica	76.24	0.00e+00	731.00
IUUC-Mmu-063325	Mus musculus	75.67	0.00e+00	738.00
IUUC-Mpu-066582	Mustela putorius furo	75.45	0.00e+00	738.00
IUUC-Nle-069624	Nomascus leucogenys	76.63	0.00e+00	743.00
IUUC-Ont-072266	Oreochromis niloticus	70.69	0.00e+00	695.00
IUUC-Ocu-073907	Oryctolagus cuniculus	76.12	0.00e+00	741.00
IUUC-Ola-086668	Oryzias latipes	70.56	0.00e+00	683.00
IUUC-Oga-088057	Otolemur garnettii	76.63	0.00e+00	738.00
IUUC-Oar-089332	Ovis aries	72.10	0.00e+00	692.00
IUUC-Ptr-091551	Pan troglodytes	74.65	0.00e+00	696.00
IUUC-Pan-092173	Papio anubis	77.08	0.00e+00	746.00
IUUC-Psi-093895	Pelodiscus sinensis	85.59	0.00e+00	814.00
IUUC-Pfo-096608	Poecilia formosa	72.48	0.00e+00	697.00
IUUC-Pab-097598	Pongo abelii	77.48	0.00e+00	746.00
IUUC-Pva-102135	Pteropus vampyrus	75.67	0.00e+00	733.00
IUUC-Rno-104891	Rattus norvegicus	75.45	0.00e+00	738.00
IUUC-Sha-107192	Sarcophilus harrisii	76.73	0.00e+00	738.00
IUUC-Ssc-115696	Sus scrofa	76.56	0.00e+00	744.00
IUUC-Tgu-117056	Taeniopygia guttata	91.87	0.00e+00	858.00
IUUC-Tru-117621	Takifugu rubripes	67.26	0.00e+00	662.00
IUUC-Ttr-128457	Tursiops truncatus	75.67	0.00e+00	731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence