iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aor-010241

Ensembl Protein ID

BAE62977

UniProt Accession

Q2U638; Q2U638_ASPOR

Genbank Protein ID

BAE62977.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AP007166

Gene Name

AO090120000394

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AO090120000394	BAE62977	BAE62977

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	1.30e-124	416.5	40	652

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 15   vkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkk..veesedeq..lLktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLald 110
            + ++eely++++n+c +  +  l ++l+e +  ++  +++ +  v+++ +++   L++++  W+ ++ +l+ +r if yld+++   sk+   +r+++l 
   Q: 40   PEISLEELYKGAENVCRQGRASALARQLQERCRGHVsGKLRDTlvVKAAGGNNidTLRAVVDSWTTWQSKLVTVRWIFYYLDQSFLLHSKEYPVIREMGLI 140
           56789*******************************87776542245555666678********************************9999********* PP
   S: 111  lwrkeived..ikkrllelllklieaeRkge...avdrrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqenevdeYlkkvearlne 206
            +r++i++d  ++ ++l+ + +l+ea+R++      d++ll++++e +  L      +y++ FE +   ++++f++  +++  ++  +  + ++    +++
   Q: 141  QFRQHIFNDtvLQPQVLQGACDLVEADRDEGrsiSADSSLLRNAIEFFHGL-----DVYTTGFEPLLVSESKKFFASWAQHE-ASGYLATFAENSHRLIEQ 235
           **********99****************986222579**********9888.....8******************9887764.55778889999999999* PP
   S: 207  eeeraa.ryleestetkLlevvekeliakhlesll..aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerl 304
           e +r+  ++l+ st++kL e +++el+a++ + ll  +++  llr  ++  l+++y Ll+r   g  +l   ++s+i e+g+ ++ +  ke +   +V rl
   Q: 236  EVDRCTlFSLNRSTKQKLSELLDQELVAEQENVLLnqNDILGLLRAGNKTALEKLYTLLQRRDLGA-KLKTAFSSYIVEEGTSIVFDDDKEAE---MVVRL 332
           ****9735789999********************9888999********************88885.79*******************99999...***** PP
   S: 305  lelknklqklvseaFnndakFlkaldkafetfvnknsvlka......akspEllAryiDqlLrkssk.....gl.......teeeleaqldkvllvfkyis 387
           l++k++l++  +++F+  ++  +al++afetf+nk     a      +k+ E++A+y+D lL+++ k     ++       +++e+++qld+vl +f++++
   Q: 333  LDFKQQLDETWNNSFHRHEELGHALREAFETFMNKGRKSGAsggtdnPKTGEMIAKYVDRLLKGGWKlppgrKAedvpladEDAEINRQLDQVLDLFRFVH 433
           ***********************************95544499*999******************662222222222333357899*************** PP
   S: 388  ekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLP 488
           +k vFe++Yk++La+RLl g sas++aE+s++ +Lk+ecg  ft+ Le Mf+d+ v +d ++++++ +++ +    v+l+v+vLsa aWp +++ + v +P
   Q: 434  GKAVFEAFYKNDLARRLLMGRSASDDAEKSMLARLKTECGSSFTHNLESMFKDMDVARDEMAAYNSIQRERKHRLPVDLNVSVLSAAAWPSYPDVQ-VRIP 533
           *****************************************************************999999999******************9966.**** PP
   S: 489  aelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnns...ekvsveelkkatelpeeeLrrtlqsLvsskkqvlkke 586
           +e+  ++ +fe+fY +k +gRkL+W+h+l++++l+a + kg +el Vs fQ++vLL+fn+     ++s+ ++++at+l+++eL+rtlqsL++ k +vl k+
   Q: 534  PEIATAVSDFEKFYYSKYNGRKLNWKHQLAHCQLRARFPKGDKELVVSSFQAIVLLLFNDIsekGTLSYLQIQEATKLSDQELKRTLQSLACAKYRVLAKK 634
           ***********************************************************97555789********************************** PP
   S: 587  peskeieeedlfsvNqef 604
           p+++e++ +d fs N+ f
   Q: 635  PKGREVNTTDEFSYNEGF 652
           ***************987 PP

Organism

Aspergillus oryzae

Protein Sequence
(Fasta)

MAGTTLIEAI CDDAYADSYF EKIWGQLDAA LTAIFDGGKP EISLEELYKG AENVCRQGRA 60
SALARQLQER CRGHVSGKLR DTLVVKAAGG NNIDTLRAVV DSWTTWQSKL VTVRWIFYYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGCA CCACACTGAT TGAAGCGATA TGCGATGATG CATATGCTGG TCAGGAGACA 60
TGTCGCGTGT CTGCTCTATT GTTCCTCAAT CTCCTTGCAG CCCTCGATAA ACAGGGTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0000775--C:chromosome, centromeric region
GO:0000781--C:chromosome, telomeric region
GO:0043494--C:CLRC ubiquitin ligase complex
GO:0008180--C:COP9 signalosome
GO:0005829--C:cytosol
GO:0034613--P:cellular protein localization
GO:0030702--P:chromatin silencing at centromere
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0006348--P:chromatin silencing at telomere
GO:0031048--P:chromatin silencing by small RNA
GO:0031507--P:heterochromatin assembly
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0051446--P:positive regulation of meiotic cell cycle
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0051570--P:regulation of histone H3-K9 methylation
GO:0006283--P:transcription-coupled nucleotide-excision repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000285	Aegilops tauschii	37.47	1.00e-137	482.00
IUUC-Aml-002062	Ailuropoda melanoleuca	37.94	5.00e-136	476.00
IUUC-Atr-002727	Amborella trichopoda	37.45	6.00e-129	453.00
IUUC-Apl-004157	Anas platyrhynchos	38.12	7.00e-136	476.00
IUUC-Aca-004430	Anolis carolinensis	37.69	4.00e-135	473.00
IUUC-Aly-006547	Arabidopsis lyrata	36.74	5.00e-128	450.00
IUUC-Ath-006748	Arabidopsis thaliana	37.01	4.00e-127	446.00
IUUC-Acl-008359	Aspergillus clavatus	78.07	0.00e+00	1162.00
IUUC-Afl-008567	Aspergillus flavus	99.86	0.00e+00	1502.00
IUUC-Afu-008833	Aspergillus fumigatus	79.55	0.00e+00	1219.00
IUUC-Ani-009373	Aspergillus nidulans	81.50	0.00e+00	1233.00
IUUC-Ang-009622	Aspergillus niger	86.12	0.00e+00	1309.00
IUUC-Ate-010251	Aspergillus terreus	87.62	0.00e+00	1340.00
IUUC-Ame-010809	Astyanax mexicanus	37.77	5.00e-132	463.00
IUUC-Bgr-012219	Blumeria graminis	44.37	7.00e-176	608.00
IUUC-Bta-012355	Bos taurus	38.61	2.00e-136	477.00
IUUC-Bci-013744	Botrytis cinerea	48.75	0.00e+00	638.00
IUUC-Bdi-014223	Brachypodium distachyon	36.66	2.00e-134	471.00
IUUC-Bol-016544	Brassica oleracea	36.57	4.00e-132	463.00
IUUC-Bra-017794	Brassica rapa	36.84	2.00e-133	468.00
IUUC-Cja-019861	Callithrix jacchus	38.09	2.00e-134	471.00
IUUC-Cfa-021189	Canis familiaris	37.77	3.00e-136	477.00
IUUC-Cpo-021867	Cavia porcellus	38.71	3.00e-136	477.00
IUUC-Cre-022739	Chlamydomonas reinhardtii	37.71	1.00e-107	382.00
IUUC-Csa-024139	Chlorocebus sabaeus	37.95	3.00e-134	470.00
IUUC-Cho-024899	Choloepus hoffmanni	42.91	2.00e-110	390.00
IUUC-Cin-025727	Ciona intestinalis	38.85	3.00e-117	414.00
IUUC-Csv-026117	Ciona savignyi	35.37	3.00e-122	430.00
IUUC-Cgl-026761	Colletotrichum gloeosporioides	44.80	1.00e-178	618.00
IUUC-Cne-027026	Cryptococcus neoformans	28.70	2.00e-75	275.00
IUUC-Cme-027355	Cyanidioschyzon merolae	29.15	3.00e-76	277.00
IUUC-Dre-027916	Danio rerio	37.72	9.00e-132	462.00
IUUC-Dno-028879	Dasypus novemcinctus	36.81	2.00e-126	444.00
IUUC-Dor-030698	Dipodomys ordii	38.04	1.00e-129	455.00
IUUC-Dse-031159	Dothistroma septosporum	51.65	0.00e+00	699.00
IUUC-Dme-031652	Drosophila melanogaster	39.27	2.00e-128	451.00
IUUC-Ete-033101	Echinops telfairi	34.63	5.00e-110	389.00
IUUC-Eca-033696	Equus caballus	38.29	2.00e-135	474.00
IUUC-Eeu-034767	Erinaceus europaeus	37.89	4.00e-129	453.00
IUUC-Fca-036211	Felis catus	38.39	8.00e-137	479.00
IUUC-Fal-037248	Ficedula albicollis	37.95	4.00e-136	476.00
IUUC-Fox-037854	Fusarium oxysporum	44.40	1.00e-172	597.00
IUUC-Fso-038138	Fusarium solani	44.85	2.00e-179	620.00
IUUC-Gmo-038754	Gadus morhua	38.47	4.00e-132	463.00
IUUC-Ggr-040003	Gaeumannomyces graminis	44.13	2.00e-156	544.00
IUUC-Gga-041002	Gallus gallus	37.95	4.00e-136	476.00
IUUC-Gac-041555	Gasterosteus aculeatus	38.07	4.00e-133	467.00
IUUC-Gma-043960	Glycine max	37.18	7.00e-138	482.00
IUUC-Ggo-045468	Gorilla gorilla	37.38	5.00e-127	446.00
IUUC-Hsa-045679	Homo sapiens	38.09	2.00e-134	471.00
IUUC-Itr-048365	Ictidomys tridecemlineatus	37.95	7.00e-137	479.00
IUUC-Lch-050417	Latimeria chalumnae	38.44	1.00e-138	485.00
IUUC-Lpe-051446	Leersia perrieri	38.01	3.00e-139	487.00
IUUC-Loc-051804	Lepisosteus oculatus	37.27	1.00e-131	462.00
IUUC-Lma-053080	Leptosphaeria maculans	52.47	0.00e+00	769.00
IUUC-Laf-053701	Loxodonta africana	37.95	5.00e-137	480.00
IUUC-Mcc-055538	Macaca mulatta	37.69	3.00e-134	471.00
IUUC-Mor-057102	Magnaporthe oryzae	43.98	1.00e-173	601.00
IUUC-Mpo-057342	Magnaporthe poae	45.48	1.00e-152	531.00
IUUC-Mtr-058660	Medicago truncatula	37.65	5.00e-132	462.00
IUUC-Mla-058936	Melampsora laricipopulina	34.93	7.00e-93	333.00
IUUC-Mga-059754	Meleagris gallopavo	38.12	1.00e-135	475.00
IUUC-Mvi-060455	Microbotryum violaceum	36.63	5.00e-110	390.00
IUUC-Mmr-060870	Microcebus murinus	38.22	2.00e-136	477.00
IUUC-Mdo-062215	Monodelphis domestica	37.69	1.00e-133	468.00
IUUC-Mmu-063751	Mus musculus	37.82	2.00e-136	478.00
IUUC-Mac-064443	Musa acuminata	38.02	8.00e-142	495.00
IUUC-Mpu-065903	Mustela putorius furo	37.82	5.00e-136	476.00
IUUC-Mlu-068213	Myotis lucifugus	37.82	2.00e-136	477.00
IUUC-Nfi-068363	Neosartorya fischeri	80.89	0.00e+00	1230.00
IUUC-Ncr-068950	Neurospora crassa	45.36	1.00e-172	598.00
IUUC-Nle-069606	Nomascus leucogenys	38.09	2.00e-134	471.00
IUUC-Ont-071562	Oreochromis niloticus	38.04	3.00e-133	467.00
IUUC-Oan-073607	Ornithorhynchus anatinus	37.95	5.00e-136	476.00
IUUC-Ocu-074446	Oryctolagus cuniculus	37.82	4.00e-136	476.00
IUUC-Oba-075198	Oryza barthii	37.87	2.00e-138	484.00
IUUC-Obr-076095	Oryza brachyantha	37.87	8.00e-139	486.00
IUUC-Ogl-077032	Oryza glaberrima	38.02	1.00e-138	485.00
IUUC-Ogu-078051	Oryza glumaepatula	37.87	1.00e-138	485.00
IUUC-Oin-079399	Oryza indica	40.42	3.00e-126	443.00
IUUC-Olo-080988	Oryza longistaminata	38.01	1.00e-139	488.00
IUUC-Ome-081600	Oryza meridionalis	38.01	5.00e-140	489.00
IUUC-Oni-082623	Oryza nivara	38.16	7.00e-140	489.00
IUUC-Opu-083762	Oryza punctata	37.20	1.00e-135	476.00
IUUC-Oru-084499	Oryza rufipogon	37.87	2.00e-138	484.00
IUUC-Ola-087101	Oryzias latipes	38.04	6.00e-132	462.00
IUUC-Olu-087650	Ostreococcus lucimarinus	36.87	2.00e-116	410.00
IUUC-Oga-088416	Otolemur garnettii	37.35	1.00e-132	465.00
IUUC-Oar-089346	Ovis aries	38.61	5.00e-137	479.00
IUUC-Ptr-091177	Pan troglodytes	38.09	2.00e-134	471.00
IUUC-Pan-092191	Papio anubis	38.07	2.00e-134	471.00
IUUC-Psi-093773	Pelodiscus sinensis	37.85	2.00e-135	474.00
IUUC-Pma-094678	Petromyzon marinus	34.47	2.00e-93	334.00
IUUC-Pno-094946	Phaeosphaeria nodorum	50.93	0.00e+00	674.00
IUUC-Ppa-095688	Physcomitrella patens	38.97	3.00e-145	507.00
IUUC-Pfo-097037	Poecilia formosa	37.90	4.00e-133	466.00
IUUC-Pab-097622	Pongo abelii	38.49	1.00e-135	475.00
IUUC-Pca-100391	Procavia capensis	46.23	6.00e-97	346.00
IUUC-Ppe-101142	Prunus persica	37.01	2.00e-131	461.00
IUUC-Pva-102995	Pteropus vampyrus	42.02	1.00e-108	385.00
IUUC-Pgr-103334	Puccinia graminis	33.88	4.00e-85	307.00
IUUC-Ptt-103903	Puccinia triticina	37.35	2.00e-76	278.00
IUUC-Pte-104167	Pyrenophora teres	52.60	0.00e+00	776.00
IUUC-Pyt-104736	Pyrenophora triticirepentis	52.53	0.00e+00	769.00
IUUC-Rno-106119	Rattus norvegicus	37.82	3.00e-136	477.00
IUUC-Sha-106958	Sarcophilus harrisii	37.55	5.00e-133	466.00
IUUC-Sja-107940	Schizosaccharomyces japonicus	33.92	5.00e-109	386.00
IUUC-Spo-108109	Schizosaccharomyces pombe	33.83	3.00e-112	397.00
IUUC-Ssl-108537	Sclerotinia sclerotiorum	47.35	2.00e-178	617.00
IUUC-Smo-108872	Selaginella moellendorffii	38.35	5.00e-142	496.00
IUUC-Sit-110626	Setaria italica	37.20	3.00e-135	474.00
IUUC-Sly-111056	Solanum lycopersicum	37.95	6.00e-135	473.00
IUUC-Sar-112956	Sorex araneus	50.15	1.00e-94	338.00
IUUC-Sbi-113931	Sorghum bicolor	37.06	2.00e-134	471.00
IUUC-Sre-114943	Sporisorium reilianum	37.27	1.00e-105	375.00
IUUC-Ssc-116133	Sus scrofa	38.22	7.00e-130	456.00
IUUC-Tgu-116462	Taeniopygia guttata	37.95	1.00e-135	475.00
IUUC-Tru-118299	Takifugu rubripes	37.82	2.00e-133	468.00
IUUC-Tsy-119517	Tarsius syrichta	48.63	1.00e-95	342.00
IUUC-Tni-119798	Tetraodon nigroviridis	38.12	6.00e-131	459.00
IUUC-Tca-121626	Theobroma cacao	36.93	9.00e-138	482.00
IUUC-Tre-121907	Trichoderma reesei	46.27	2.00e-180	624.00
IUUC-Tvi-122568	Trichoderma virens	45.51	3.00e-179	620.00
IUUC-Tae-123442	Triticum aestivum	37.47	4.00e-138	483.00
IUUC-Tur-126032	Triticum urartu	37.62	4.00e-138	483.00
IUUC-Tme-127162	Tuber melanosporum	46.16	3.00e-162	563.00
IUUC-Tbe-127658	Tupaia belangeri	37.94	3.00e-131	460.00
IUUC-Ttr-128326	Tursiops truncatus	36.51	3.00e-113	400.00
IUUC-Uma-129531	Ustilago maydis	37.39	3.00e-93	334.00
IUUC-Vda-129701	Verticillium dahliae	44.56	0.00e+00	629.00
IUUC-Vpa-130217	Vicugna pacos	32.43	4.00e-105	374.00
IUUC-Vvi-131133	Vitis vinifera	37.16	4.00e-138	483.00
IUUC-Xtr-132761	Xenopus tropicalis	37.65	3.00e-131	460.00
IUUC-Xma-134069	Xiphophorus maculatus	36.46	1.00e-126	445.00
IUUC-Zma-135529	Zea mays	37.33	1.00e-133	468.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence