iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116273

Ensembl Protein ID

ENSSSCP00000020556.1

UniProt Accession

I3L945; I3L945_PIG

Protein Name

Uncharacterized protein

Gene Name

LOC100625317

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000022559.1	ENSSSCT00000027919.1	ENSSSCP00000020556.1
ENSSSCG00000022559.1	ENSSSCT00000031626.1	ENSSSCP00000026835.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-65	221.4	105	475
ULD/UDP/UBQ/UBQ_Other	2.50e-09	37.1	6	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+++l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCIRSVPELKDALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekge 191
           7******************************.****************************.99999******************999*9 PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+  ++ +++e+ ++       +a+  +++k+ksli++ F++++++++kc e +++ +++ + ++l
   Q: 192  qgQYLQQDANECWIQMMRVLQQKLEAIEDDTVKETDSS-------SASAVTPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQL 273
           999*********************66555555554333.......47788999************************999999888888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +     ++++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 274  QLSCFINQEV--KYLFTGLKLRLQEEITK-----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDV 355
           8888877754..58999999999999998.....58899999999******************************************** PP
   S: 262  spfcts........................peekqke......................kkkYeLiavvvHsG.slssGHYvayvknek 303
            + ct                         +     +                      +  Y+L av+ H+G s+ssGHYv++vk ++
   Q: 356  YELCTPelsfrskfkdledkkvnqqpkasdK-----KsspqkevkyepfsfaddigsnnCGYYDLQAVLTHQGrSSSSGHYVSWVKRKQ 439
           ******8888888888877777666655550.....14555556666667777777766****************************** PP
   S: 304  gkWllfdDskVtevkeeevleetg....staYvlfY 335
           ++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 440  DEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 475
           *********************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           vtvk+ + +  ++++n +++  ++K +++ ++g++p++q+ ++kG  L+dd ++++ ++k+g+t++++ +
   Q: 6    VTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDD-DWGNIKIKNGMTLLMMGS 74
           89*******99*************************************999.9**************965 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

YGLFAVTVKW GKEKFEGVEL NTDEPPMVFK AQLFALTGVQ PARQKVMVKG GTLKDDDWGN 60
IKIKNGMTLL MMGSADALPE EPSAKTVFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATGGTTTAT TTGCAGTTAC TGTGAAATGG GGAAAGGAGA AATTTGAAGG TGTGGAACTG 60
AATACTGATG AACCTCCCAT GGTGTTCAAG GCTCAGCTTT TTGCATTGAC TGGAGTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	30.83	5.00e-64	238.00
IUUC-Aml-002053	Ailuropoda melanoleuca	98.16	0.00e+00	923.00
IUUC-Atr-002725	Amborella trichopoda	41.77	6.00e-100	357.00
IUUC-Apl-004031	Anas platyrhynchos	91.04	0.00e+00	888.00
IUUC-Aca-004361	Anolis carolinensis	89.84	0.00e+00	899.00
IUUC-Aly-006176	Arabidopsis lyrata	42.69	8.00e-110	390.00
IUUC-Ath-007623	Arabidopsis thaliana	42.40	3.00e-110	391.00
IUUC-Ago-007796	Ashbya gossypii	32.85	1.00e-57	216.00
IUUC-Acl-008258	Aspergillus clavatus	37.16	2.00e-64	239.00
IUUC-Afl-008732	Aspergillus flavus	34.15	1.00e-79	290.00
IUUC-Afu-008755	Aspergillus fumigatus	37.74	2.00e-67	250.00
IUUC-Ani-009148	Aspergillus nidulans	39.11	5.00e-70	258.00
IUUC-Ang-009878	Aspergillus niger	38.21	6.00e-65	241.00
IUUC-Aor-010239	Aspergillus oryzae	33.80	2.00e-79	290.00
IUUC-Ate-010243	Aspergillus terreus	34.04	3.00e-72	265.00
IUUC-Ame-011327	Astyanax mexicanus	50.81	4.00e-128	451.00
IUUC-Bgr-012231	Blumeria graminis	34.26	4.00e-75	275.00
IUUC-Bta-012553	Bos taurus	96.74	0.00e+00	939.00
IUUC-Bci-013606	Botrytis cinerea	40.74	3.00e-70	259.00
IUUC-Bdi-014567	Brachypodium distachyon	43.35	3.00e-111	395.00
IUUC-Bol-016127	Brassica oleracea	42.60	1.00e-112	399.00
IUUC-Bra-017501	Brassica rapa	42.40	6.00e-112	397.00
IUUC-Cel-018140	Caenorhabditis elegans	41.40	6.00e-98	350.00
IUUC-Cja-019516	Callithrix jacchus	96.56	0.00e+00	937.00
IUUC-Cfa-020808	Canis familiaris	97.96	0.00e+00	951.00
IUUC-Cpo-021688	Cavia porcellus	96.55	0.00e+00	932.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	37.80	4.00e-81	295.00
IUUC-Csa-023429	Chlorocebus sabaeus	97.56	0.00e+00	920.00
IUUC-Cho-024347	Choloepus hoffmanni	96.54	0.00e+00	941.00
IUUC-Cin-025198	Ciona intestinalis	55.21	6.00e-151	527.00
IUUC-Csv-026007	Ciona savignyi	53.23	2.00e-151	528.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	39.46	1.00e-62	234.00
IUUC-Cne-026963	Cryptococcus neoformans	34.75	3.00e-74	271.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.35	3.00e-60	225.00
IUUC-Dre-027647	Danio rerio	81.76	0.00e+00	816.00
IUUC-Dno-029967	Dasypus novemcinctus	96.74	0.00e+00	914.00
IUUC-Dor-030886	Dipodomys ordii	91.34	0.00e+00	748.00
IUUC-Dse-031466	Dothistroma septosporum	36.04	4.00e-57	215.00
IUUC-Dme-032079	Drosophila melanogaster	55.07	4.00e-156	544.00
IUUC-Ete-032351	Echinops telfairi	85.13	0.00e+00	840.00
IUUC-Eca-033461	Equus caballus	97.35	0.00e+00	988.00
IUUC-Eeu-035220	Erinaceus europaeus	74.33	0.00e+00	692.00
IUUC-Fca-036210	Felis catus	98.17	0.00e+00	952.00
IUUC-Fal-037528	Ficedula albicollis	90.39	0.00e+00	864.00
IUUC-Fox-037805	Fusarium oxysporum	40.21	5.00e-69	254.00
IUUC-Fso-038177	Fusarium solani	38.34	3.00e-66	246.00
IUUC-Gmo-038953	Gadus morhua	76.89	0.00e+00	755.00
IUUC-Ggr-039972	Gaeumannomyces graminis	40.06	1.00e-62	233.00
IUUC-Gga-040462	Gallus gallus	89.61	0.00e+00	872.00
IUUC-Gac-041312	Gasterosteus aculeatus	81.86	0.00e+00	790.00
IUUC-Gma-043255	Glycine max	43.03	1.00e-107	383.00
IUUC-Ggo-045458	Gorilla gorilla	82.63	0.00e+00	793.00
IUUC-Hsa-045706	Homo sapiens	97.56	0.00e+00	919.00
IUUC-Hvu-047821	Hordeum vulgare	46.76	8.00e-58	216.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	96.54	0.00e+00	936.00
IUUC-Lch-050464	Latimeria chalumnae	82.24	0.00e+00	818.00
IUUC-Lpe-051419	Leersia perrieri	42.07	4.00e-107	381.00
IUUC-Loc-052732	Lepisosteus oculatus	81.06	0.00e+00	832.00
IUUC-Lma-053177	Leptosphaeria maculans	42.11	3.00e-71	262.00
IUUC-Laf-053822	Loxodonta africana	97.96	0.00e+00	950.00
IUUC-Mcc-055893	Macaca mulatta	97.56	0.00e+00	919.00
IUUC-Meu-056307	Macropus eugenii	81.56	0.00e+00	782.00
IUUC-Mor-057171	Magnaporthe oryzae	40.60	6.00e-66	244.00
IUUC-Mpo-057415	Magnaporthe poae	39.34	1.00e-68	253.00
IUUC-Mtr-057901	Medicago truncatula	42.77	7.00e-110	390.00
IUUC-Mla-058897	Melampsora laricipopulina	40.11	7.00e-75	274.00
IUUC-Mga-060016	Meleagris gallopavo	90.63	0.00e+00	884.00
IUUC-Mvi-060562	Microbotryum violaceum	39.95	5.00e-67	248.00
IUUC-Mmr-060624	Microcebus murinus	96.33	0.00e+00	983.00
IUUC-Mdo-061809	Monodelphis domestica	92.07	0.00e+00	882.00
IUUC-Mmu-063869	Mus musculus	95.52	0.00e+00	927.00
IUUC-Mac-064876	Musa acuminata	39.52	5.00e-94	338.00
IUUC-Mpu-066480	Mustela putorius furo	97.56	0.00e+00	947.00
IUUC-Mlu-067866	Myotis lucifugus	96.95	0.00e+00	953.00
IUUC-Nfi-068393	Neosartorya fischeri	37.03	4.00e-65	242.00
IUUC-Ncr-068815	Neurospora crassa	41.03	1.00e-67	250.00
IUUC-Nle-070121	Nomascus leucogenys	98.41	6.00e-139	486.00
IUUC-Opr-070712	Ochotona princeps	76.17	4.00e-170	590.00
IUUC-Ont-071544	Oreochromis niloticus	81.60	0.00e+00	755.00
IUUC-Oan-073635	Ornithorhynchus anatinus	90.63	0.00e+00	738.00
IUUC-Ocu-074926	Oryctolagus cuniculus	95.52	0.00e+00	909.00
IUUC-Oba-075633	Oryza barthii	42.20	6.00e-107	380.00
IUUC-Obr-076423	Oryza brachyantha	43.06	2.00e-109	389.00
IUUC-Ogl-077913	Oryza glaberrima	41.63	5.00e-109	387.00
IUUC-Ogu-078435	Oryza glumaepatula	42.20	6.00e-107	380.00
IUUC-Oin-080072	Oryza indica	42.15	2.00e-107	382.00
IUUC-Olo-080535	Oryza longistaminata	39.39	1.00e-91	330.00
IUUC-Ome-081309	Oryza meridionalis	42.20	6.00e-107	380.00
IUUC-Oni-083113	Oryza nivara	42.20	6.00e-107	380.00
IUUC-Opu-083168	Oryza punctata	41.25	2.00e-101	362.00
IUUC-Oru-084253	Oryza rufipogon	42.20	6.00e-107	380.00
IUUC-Osa-085554	Oryza sativa	41.63	4.00e-109	387.00
IUUC-Ola-086998	Oryzias latipes	80.45	0.00e+00	780.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.20	3.00e-71	262.00
IUUC-Oga-088571	Otolemur garnettii	96.54	0.00e+00	935.00
IUUC-Oar-089526	Ovis aries	97.36	0.00e+00	949.00
IUUC-Ptr-091433	Pan troglodytes	97.56	0.00e+00	919.00
IUUC-Pan-091966	Papio anubis	97.56	0.00e+00	920.00
IUUC-Psi-093458	Pelodiscus sinensis	88.36	0.00e+00	840.00
IUUC-Pma-094343	Petromyzon marinus	69.69	3.00e-122	430.00
IUUC-Pno-095109	Phaeosphaeria nodorum	40.78	2.00e-65	243.00
IUUC-Ppa-095756	Physcomitrella patens	43.14	5.00e-110	390.00
IUUC-Pfo-096514	Poecilia formosa	82.00	0.00e+00	772.00
IUUC-Pab-098477	Pongo abelii	85.53	0.00e+00	730.00
IUUC-Pop-099221	Populus trichocarpa	41.77	8.00e-103	367.00
IUUC-Pca-100791	Procavia capensis	80.85	2.00e-180	624.00
IUUC-Ppe-101812	Prunus persica	42.37	9.00e-106	377.00
IUUC-Pva-102462	Pteropus vampyrus	92.52	0.00e+00	766.00
IUUC-Pgr-103623	Puccinia graminis	40.74	8.00e-76	277.00
IUUC-Ptt-103767	Puccinia triticina	40.12	1.00e-67	250.00
IUUC-Pte-104109	Pyrenophora teres	40.31	1.00e-69	256.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.84	5.00e-71	261.00
IUUC-Rno-105351	Rattus norvegicus	95.52	0.00e+00	884.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.80	2.00e-62	233.00
IUUC-Sha-107491	Sarcophilus harrisii	92.06	0.00e+00	900.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	34.38	2.00e-76	279.00
IUUC-Spo-108174	Schizosaccharomyces pombe	37.40	8.00e-79	287.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	35.59	2.00e-83	303.00
IUUC-Smo-108805	Selaginella moellendorffii	43.30	4.00e-108	384.00
IUUC-Sit-110361	Setaria italica	42.77	2.00e-112	399.00
IUUC-Sly-110965	Solanum lycopersicum	40.39	6.00e-106	377.00
IUUC-Sar-113355	Sorex araneus	83.18	0.00e+00	648.00
IUUC-Sbi-114778	Sorghum bicolor	44.08	2.00e-112	399.00
IUUC-Sre-115011	Sporisorium reilianum	35.64	1.00e-62	233.00
IUUC-Tgu-117063	Taeniopygia guttata	89.82	0.00e+00	865.00
IUUC-Tru-118381	Takifugu rubripes	78.98	0.00e+00	782.00
IUUC-Tsy-119076	Tarsius syrichta	80.60	3.00e-113	401.00
IUUC-Tni-119941	Tetraodon nigroviridis	80.82	0.00e+00	773.00
IUUC-Tca-121246	Theobroma cacao	42.09	6.00e-108	384.00
IUUC-Tre-121969	Trichoderma reesei	39.78	3.00e-66	245.00
IUUC-Tvi-122543	Trichoderma virens	33.69	7.00e-70	257.00
IUUC-Tae-125484	Triticum aestivum	42.60	7.00e-109	387.00
IUUC-Tur-126128	Triticum urartu	32.92	3.00e-67	249.00
IUUC-Tbe-128030	Tupaia belangeri	89.94	0.00e+00	846.00
IUUC-Ttr-128701	Tursiops truncatus	96.45	0.00e+00	765.00
IUUC-Uma-129657	Ustilago maydis	36.46	8.00e-65	241.00
IUUC-Vda-129723	Verticillium dahliae	36.44	8.00e-57	214.00
IUUC-Vpa-130284	Vicugna pacos	71.05	0.00e+00	642.00
IUUC-Vvi-131037	Vitis vinifera	42.77	7.00e-107	380.00
IUUC-Xtr-132235	Xenopus tropicalis	84.18	0.00e+00	859.00
IUUC-Xma-133840	Xiphophorus maculatus	82.00	0.00e+00	798.00
IUUC-Yli-134453	Yarrowia lipolytica	36.78	8.00e-80	290.00
IUUC-Zma-135669	Zea mays	36.85	8.00e-95	340.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence