iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067991

Ensembl Protein ID

ENSMLUP00000019276.1

UniProt Accession

G1Q6E3; G1Q6E3_MYOLU

Genbank Protein ID

ENSMLUP00000019276

Protein Name

Small ubiquitin-related modifier

Genbank Nucleotide ID

AAPE02031734

Gene Name

SUMO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000026004.1	ENSMLUT00000023175.1	ENSMLUP00000019276.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	1.80e-30	105.5	20	97
ULD/UDP/UBQ/UBQ_Other	2.70e-06	27.2	28	95

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 7    apvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
           ++++lkv gqd+se++fk+k++++lkkl+e+ Y++r+++ +ns+rf+f+gq+i++++tp+el++e+ed++e++++++GG
   Q: 20   EYIKLKVIGQDSSEIHFKVKMTTHLKKLKES-YCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVVEVYQEQTGG 97
           79*****************************.**********************************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 7    sldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
             d+se  +kv+ ++  ++LKe   +++g+p+++ r +++G+ + d++t +++g+ +++++ +++++ 
   Q: 28   GQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVVEVYQEQT 95
           445557778899999*************************************************9875 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MSDQEAKPST EDVGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN 60
SLRFLFEGQR IADNHTPKEL GMEEEDVVEV YQEQTGGHLT V 101

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGACC AGGAGGCAAA ACCTTCAACT GAGGACGTGG GGGATAAGAA GGAAGGAGAA 60
TACATTAAAC TCAAAGTCAT TGGACAGGAT AGCAGTGAGA TTCACTTCAA AGTGAAAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0097165--C:nuclear stress granule
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008076--C:voltage-gated potassium channel complex
GO:0001741--C:XY body
GO:0015459--F:potassium channel regulator activity
GO:0003723--F:RNA binding
GO:0008134--F:transcription factor binding
GO:0071276--P:cellular response to cadmium ion
GO:0034605--P:cellular response to heat
GO:0045759--P:negative regulation of action potential
GO:1902260--P:negative regulation of delayed rectifier potassium channel activity
GO:0043392--P:negative regulation of DNA binding
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0060021--P:palate development
GO:0030578--P:PML body organization
GO:1901896--P:positive regulation of calcium-transporting ATPase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0090204--P:protein localization to nuclear pore
GO:0050821--P:protein stabilization
GO:0016925--P:protein sumoylation
GO:0086004--P:regulation of cardiac muscle cell contraction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001056	Aegilops tauschii	40.54	6.00e-17	79.00
IUUC-Aca-004710	Anolis carolinensis	95.92	9.00e-53	197.00
IUUC-Ago-007749	Ashbya gossypii	47.96	1.00e-18	83.60
IUUC-Ame-011662	Astyanax mexicanus	83.00	9.00e-45	171.00
IUUC-Bta-013491	Bos taurus	97.03	6.00e-55	204.00
IUUC-Cfa-020657	Canis familiaris	96.04	9.00e-55	204.00
IUUC-Cre-022970	Chlamydomonas reinhardtii	46.39	6.00e-20	88.60
IUUC-Csa-023026	Chlorocebus sabaeus	96.04	7.00e-45	171.00
IUUC-Dre-028383	Danio rerio	85.57	6.00e-44	168.00
IUUC-Dno-029820	Dasypus novemcinctus	97.03	6.00e-55	204.00
IUUC-Eca-033958	Equus caballus	96.04	9.00e-55	204.00
IUUC-Eeu-034822	Erinaceus europaeus	97.96	4.00e-54	202.00
IUUC-Gga-040129	Gallus gallus	95.05	7.00e-54	201.00
IUUC-Gac-042112	Gasterosteus aculeatus	86.60	1.00e-46	177.00
IUUC-Ggo-045413	Gorilla gorilla	97.03	6.00e-55	204.00
IUUC-Hsa-046108	Homo sapiens	97.03	6.00e-55	204.00
IUUC-Itr-047968	Ictidomys tridecemlineatus	97.00	2.00e-54	202.00
IUUC-Lch-049881	Latimeria chalumnae	85.57	2.00e-39	152.00
IUUC-Meu-056112	Macropus eugenii	94.06	3.00e-53	200.00
IUUC-Mmr-060903	Microcebus murinus	97.03	6.00e-55	204.00
IUUC-Mdo-062633	Monodelphis domestica	94.06	2.00e-53	199.00
IUUC-Mmu-063272	Mus musculus	97.03	6.00e-55	204.00
IUUC-Opr-070351	Ochotona princeps	46.53	1.00e-16	78.60
IUUC-Ont-071436	Oreochromis niloticus	86.60	1.00e-46	177.00
IUUC-Oan-072986	Ornithorhynchus anatinus	94.44	2.00e-25	106.00
IUUC-Ocu-073781	Oryctolagus cuniculus	94.06	1.00e-52	196.00
IUUC-Ola-086373	Oryzias latipes	85.57	4.00e-45	172.00
IUUC-Oga-088024	Otolemur garnettii	91.67	2.00e-49	186.00
IUUC-Ptr-090688	Pan troglodytes	95.05	1.00e-53	200.00
IUUC-Pan-092204	Papio anubis	97.03	6.00e-55	204.00
IUUC-Pfo-096306	Poecilia formosa	85.00	4.00e-46	176.00
IUUC-Pab-098393	Pongo abelii	97.03	8.00e-55	206.00
IUUC-Pop-099042	Populus trichocarpa	43.43	1.00e-20	90.90
IUUC-Pca-100237	Procavia capensis	96.04	1.00e-52	198.00
IUUC-Pva-102353	Pteropus vampyrus	98.73	7.00e-43	165.00
IUUC-Rno-105286	Rattus norvegicus	97.03	6.00e-55	204.00
IUUC-Spo-108261	Schizosaccharomyces pombe	50.00	4.00e-22	96.30
IUUC-Ssc-115837	Sus scrofa	94.06	1.00e-53	200.00
IUUC-Tru-117752	Takifugu rubripes	87.63	4.00e-47	178.00
IUUC-Tni-120621	Tetraodon nigroviridis	86.60	3.00e-46	175.00
IUUC-Ttr-128166	Tursiops truncatus	95.05	1.00e-53	201.00
IUUC-Vpa-130172	Vicugna pacos	97.03	8.00e-55	205.00
IUUC-Xtr-132473	Xenopus tropicalis	90.20	2.00e-50	189.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence