iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121246

Ensembl Protein ID

EOY27059

UniProt Accession

A0A061GJ15; A0A061GJ15_THECC

Genbank Protein ID

EOY27059.1

Protein Name

Ubiquitin-specific protease 6

Genbank Nucleotide ID

CM001884

Gene Name

TCM_028999

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_028999	EOY27059	EOY27059

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-61	208.9	105	478
ULD/UDP/UBQ/UBQ_Other	2.70e-09	37.7	6	73

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.....gyeqqDaqEfla 97
           Gl NlgNtCYmNS++QcL+++pel+++l + ++++ + ++ ++++  l+ + ++lf+el +++ k v+p +++ +l+k+ ++f       ++qqDa+E+++
   Q: 105  GLFNLGNTCYMNSTVQCLHSVPELKSALVK-YSHSGRSNDLDQTSHMLTVATRDLFSEL-DKSVKPVAPMQFWMVLRKKYPQFGqlhngVFMQQDAEECWT 203
           9*****************************.888877788889999*************.99999******************98999899********** PP
   S: 98   flldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkee 198
           +ll +l+++l                       ++   ++n ++++dlF+++l s+i c+e +++ss++e+ ++l+++++++ +     l++ L++  k e
   Q: 204  QLLYTLSQSL-----------------------RSPGSSENLDTVKDLFGIELASRIHCQESGEESSETESVYSLKCHISQEVN----HLHEGLKHGLKSE 277
           **********.......................356678899**************************************9997....5777777776665 PP
   S: 199  elegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke......................... 274
            le+     ++   ++    k+ +++ lP++L++++ Rf +++e +++ ki +kv++pleLd+   c+++ +kq e                         
   Q: 278  -LEK----ASPALGRSAIYLKESRINGLPRYLTIQFVRFFWKRESNQKAKILRKVDYPLELDVYDLCSDELRKQLEgprqilrdeegkklglkanekssgt 373
           .553....578888888899*************************************************66666666666666666777777777777777 PP
   S: 275  .....................................kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg....staYvl 333
                                                + +Y+L+av+ H+G s++sGHYva+vk+e+gkW++fdD++  + +ee++++ +g    + aY++
   Q: 374  kdddvkmtdaegssnasgessattpqegvlsdkesclTGIYDLVAVLTHKGrSADSGHYVAWVKQESGKWIEFDDDNPIPQREEDIVKLSGggdwHMAYIC 474
           7777888888888888888888888999999999999***************************************************888********** PP
   S: 334  fYkr 337
           +Yk 
   Q: 475  MYKA 478
           **97 PP

ULD/UDP/UBQ/UBQ_Other

   S: 5    vksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           vk+ +     ++++ s +  ++K ++++++g+ppe+q++++kG +L+dd +++ +g+k+g++++++ +
   Q: 6    VKWQKEVFKAVEIDTSQPPYVFKCQLFDLTGVPPERQKIMVKGGLLKDDADWSTVGVKQGQKLMMVGT 73
           555565555666777777778999*****************************************976 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MLTVSVKWQK EVFKAVEIDT SQPPYVFKCQ LFDLTGVPPE RQKIMVKGGL LKDDADWSTV 60
GVKQGQKLMM VGTADEIVKA PEKGPVFMED LPEEEQVVSL GHSAGLFNLG NTCYMNSTVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAAATATCA CAGACTAAAA AATAAAATAC TTTCCCCGTT CTTCAAGCCA ACAAAAAAAA 60
AAAAAAACTC CGAAAACCCA TAGTCTCTCG CTCTTTCGAG GTCGATCCCC AACAGTAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	54.97	1.00e-85	309.00
IUUC-Aml-002053	Ailuropoda melanoleuca	41.81	2.00e-108	385.00
IUUC-Atr-002725	Amborella trichopoda	79.00	0.00e+00	746.00
IUUC-Apl-004031	Anas platyrhynchos	42.06	3.00e-108	384.00
IUUC-Aca-004361	Anolis carolinensis	41.72	2.00e-110	392.00
IUUC-Aly-006078	Arabidopsis lyrata	79.30	0.00e+00	755.00
IUUC-Ath-007623	Arabidopsis thaliana	78.88	0.00e+00	749.00
IUUC-Ago-007796	Ashbya gossypii	32.70	6.00e-62	230.00
IUUC-Acl-008258	Aspergillus clavatus	36.43	4.00e-80	291.00
IUUC-Afl-008732	Aspergillus flavus	38.22	1.00e-84	306.00
IUUC-Afu-008755	Aspergillus fumigatus	36.46	4.00e-81	294.00
IUUC-Ani-009148	Aspergillus nidulans	37.30	9.00e-85	306.00
IUUC-Ang-009878	Aspergillus niger	36.93	9.00e-81	293.00
IUUC-Aor-010239	Aspergillus oryzae	38.22	1.00e-84	306.00
IUUC-Ate-010243	Aspergillus terreus	37.38	1.00e-82	300.00
IUUC-Ame-011327	Astyanax mexicanus	27.84	4.00e-45	174.00
IUUC-Bgr-012231	Blumeria graminis	35.35	6.00e-81	294.00
IUUC-Bta-012553	Bos taurus	41.67	4.00e-108	384.00
IUUC-Bci-013606	Botrytis cinerea	37.25	7.00e-84	303.00
IUUC-Bdi-014567	Brachypodium distachyon	72.77	0.00e+00	701.00
IUUC-Bol-015565	Brassica oleracea	78.93	0.00e+00	769.00
IUUC-Bra-017297	Brassica rapa	78.40	0.00e+00	765.00
IUUC-Cel-018140	Caenorhabditis elegans	37.12	2.00e-80	291.00
IUUC-Cja-019516	Callithrix jacchus	41.37	8.00e-109	386.00
IUUC-Cfa-020808	Canis familiaris	41.76	5.00e-109	387.00
IUUC-Cpo-021688	Cavia porcellus	41.76	1.00e-108	385.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	42.47	2.00e-101	361.00
IUUC-Csa-023429	Chlorocebus sabaeus	41.73	1.00e-108	385.00
IUUC-Cho-024347	Choloepus hoffmanni	41.57	3.00e-108	384.00
IUUC-Cin-025198	Ciona intestinalis	37.75	1.00e-84	306.00
IUUC-Csv-026007	Ciona savignyi	35.66	1.00e-84	305.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	35.78	1.00e-77	283.00
IUUC-Cne-026963	Cryptococcus neoformans	36.36	1.00e-75	276.00
IUUC-Cme-027240	Cyanidioschyzon merolae	34.87	5.00e-66	244.00
IUUC-Dre-027647	Danio rerio	42.51	5.00e-112	397.00
IUUC-Dno-029967	Dasypus novemcinctus	41.54	7.00e-108	383.00
IUUC-Dor-030886	Dipodomys ordii	35.57	5.00e-74	271.00
IUUC-Dse-031466	Dothistroma septosporum	33.22	5.00e-68	251.00
IUUC-Dme-032079	Drosophila melanogaster	37.78	1.00e-92	332.00
IUUC-Ete-032351	Echinops telfairi	40.41	9.00e-100	356.00
IUUC-Eca-033461	Equus caballus	41.96	9.00e-112	396.00
IUUC-Eeu-035220	Erinaceus europaeus	33.43	6.00e-46	177.00
IUUC-Fca-036210	Felis catus	41.76	3.00e-109	387.00
IUUC-Fal-037528	Ficedula albicollis	42.23	2.00e-107	381.00
IUUC-Fox-037805	Fusarium oxysporum	44.29	1.00e-75	276.00
IUUC-Fso-038177	Fusarium solani	43.61	3.00e-72	265.00
IUUC-Gmo-038953	Gadus morhua	41.08	7.00e-104	370.00
IUUC-Ggr-039972	Gaeumannomyces graminis	36.98	4.00e-76	278.00
IUUC-Gga-040462	Gallus gallus	41.87	4.00e-108	384.00
IUUC-Gac-041312	Gasterosteus aculeatus	40.51	3.00e-107	380.00
IUUC-Gma-043255	Glycine max	84.06	0.00e+00	835.00
IUUC-Ggo-045458	Gorilla gorilla	37.18	5.00e-84	304.00
IUUC-Hsa-045706	Homo sapiens	41.73	1.00e-108	385.00
IUUC-Hvu-047821	Hordeum vulgare	72.27	1.00e-105	374.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	41.93	3.00e-110	390.00
IUUC-Lch-050464	Latimeria chalumnae	40.51	1.00e-106	379.00
IUUC-Lpe-051419	Leersia perrieri	71.93	0.00e+00	671.00
IUUC-Loc-052732	Lepisosteus oculatus	40.91	3.00e-111	394.00
IUUC-Lma-053177	Leptosphaeria maculans	41.67	3.00e-72	265.00
IUUC-Laf-053822	Loxodonta africana	41.76	2.00e-109	388.00
IUUC-Mcc-055893	Macaca mulatta	41.73	1.00e-108	385.00
IUUC-Meu-056307	Macropus eugenii	38.83	2.00e-99	355.00
IUUC-Mor-057171	Magnaporthe oryzae	37.45	2.00e-82	298.00
IUUC-Mpo-057415	Magnaporthe poae	36.58	2.00e-78	286.00
IUUC-Mtr-057901	Medicago truncatula	84.89	0.00e+00	839.00
IUUC-Mla-058897	Melampsora laricipopulina	35.52	2.00e-77	282.00
IUUC-Mga-060016	Meleagris gallopavo	41.67	1.00e-107	382.00
IUUC-Mvi-060562	Microbotryum violaceum	32.07	1.00e-68	253.00
IUUC-Mmr-060624	Microcebus murinus	42.09	4.00e-111	394.00
IUUC-Mdo-061809	Monodelphis domestica	41.93	4.00e-109	387.00
IUUC-Mmu-063869	Mus musculus	41.65	4.00e-109	387.00
IUUC-Mac-064876	Musa acuminata	73.60	0.00e+00	676.00
IUUC-Mpu-066480	Mustela putorius furo	41.76	4.00e-109	387.00
IUUC-Mlu-067866	Myotis lucifugus	41.96	1.00e-109	389.00
IUUC-Nfi-068393	Neosartorya fischeri	37.70	2.00e-81	295.00
IUUC-Ncr-068815	Neurospora crassa	37.50	2.00e-84	306.00
IUUC-Nle-070121	Nomascus leucogenys	46.76	8.00e-57	212.00
IUUC-Opr-070712	Ochotona princeps	30.86	2.00e-54	206.00
IUUC-Ont-071544	Oreochromis niloticus	41.08	2.00e-101	362.00
IUUC-Oan-073635	Ornithorhynchus anatinus	39.09	4.00e-82	297.00
IUUC-Ocu-074926	Oryctolagus cuniculus	41.62	4.00e-108	384.00
IUUC-Oba-075633	Oryza barthii	71.10	0.00e+00	666.00
IUUC-Obr-076423	Oryza brachyantha	72.41	0.00e+00	672.00
IUUC-Ogl-077913	Oryza glaberrima	73.03	0.00e+00	680.00
IUUC-Ogu-078435	Oryza glumaepatula	71.10	0.00e+00	666.00
IUUC-Oin-080072	Oryza indica	71.19	0.00e+00	665.00
IUUC-Olo-080535	Oryza longistaminata	65.71	1.00e-172	598.00
IUUC-Ome-081309	Oryza meridionalis	71.10	0.00e+00	666.00
IUUC-Oni-083113	Oryza nivara	71.10	0.00e+00	666.00
IUUC-Opu-083168	Oryza punctata	69.02	0.00e+00	636.00
IUUC-Oru-084253	Oryza rufipogon	71.10	0.00e+00	666.00
IUUC-Osa-085554	Oryza sativa	73.03	0.00e+00	680.00
IUUC-Ola-086998	Oryzias latipes	41.65	1.00e-105	375.00
IUUC-Olu-087818	Ostreococcus lucimarinus	42.97	7.00e-95	340.00
IUUC-Oga-088571	Otolemur garnettii	41.45	3.00e-108	384.00
IUUC-Oar-089526	Ovis aries	41.67	9.00e-109	386.00
IUUC-Ptr-091433	Pan troglodytes	41.73	1.00e-108	385.00
IUUC-Pan-091966	Papio anubis	41.73	1.00e-108	385.00
IUUC-Psi-093458	Pelodiscus sinensis	41.23	2.00e-101	362.00
IUUC-Pma-094343	Petromyzon marinus	41.32	1.00e-55	208.00
IUUC-Pno-095109	Phaeosphaeria nodorum	36.33	7.00e-81	293.00
IUUC-Ppa-095756	Physcomitrella patens	65.39	1.00e-178	618.00
IUUC-Pfo-096514	Poecilia formosa	41.03	1.00e-101	362.00
IUUC-Pab-098477	Pongo abelii	38.27	1.00e-78	285.00
IUUC-Pop-099221	Populus trichocarpa	86.54	0.00e+00	804.00
IUUC-Pca-100791	Procavia capensis	33.41	6.00e-56	210.00
IUUC-Ppe-101812	Prunus persica	86.54	0.00e+00	815.00
IUUC-Pva-102462	Pteropus vampyrus	38.41	2.00e-81	295.00
IUUC-Pgr-103623	Puccinia graminis	44.24	1.00e-72	266.00
IUUC-Ptt-103767	Puccinia triticina	43.17	8.00e-68	250.00
IUUC-Pte-104109	Pyrenophora teres	36.09	4.00e-82	298.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	35.66	1.00e-80	292.00
IUUC-Rno-105351	Rattus norvegicus	41.81	2.00e-108	385.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.92	6.00e-63	234.00
IUUC-Sha-107491	Sarcophilus harrisii	41.81	2.00e-108	384.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	34.55	8.00e-79	286.00
IUUC-Spo-108174	Schizosaccharomyces pombe	38.71	2.00e-79	288.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	36.25	8.00e-83	300.00
IUUC-Smo-108805	Selaginella moellendorffii	66.32	0.00e+00	632.00
IUUC-Sit-110361	Setaria italica	73.33	0.00e+00	704.00
IUUC-Sly-110965	Solanum lycopersicum	83.44	0.00e+00	810.00
IUUC-Sar-113355	Sorex araneus	39.56	5.00e-60	224.00
IUUC-Sbi-114778	Sorghum bicolor	73.49	0.00e+00	703.00
IUUC-Sre-115011	Sporisorium reilianum	38.19	6.00e-65	241.00
IUUC-Ssc-116273	Sus scrofa	41.96	2.00e-107	382.00
IUUC-Tgu-117063	Taeniopygia guttata	42.03	2.00e-107	381.00
IUUC-Tru-118381	Takifugu rubripes	41.73	9.00e-103	366.00
IUUC-Tsy-119076	Tarsius syrichta	39.06	1.00e-41	163.00
IUUC-Tni-119941	Tetraodon nigroviridis	41.78	4.00e-99	354.00
IUUC-Tre-121969	Trichoderma reesei	34.51	2.00e-72	266.00
IUUC-Tvi-122543	Trichoderma virens	35.21	4.00e-78	284.00
IUUC-Tae-125484	Triticum aestivum	71.37	0.00e+00	689.00
IUUC-Tur-126128	Triticum urartu	55.41	2.00e-82	298.00
IUUC-Tbe-128030	Tupaia belangeri	36.76	5.00e-89	320.00
IUUC-Ttr-128701	Tursiops truncatus	38.32	1.00e-78	286.00
IUUC-Uma-129657	Ustilago maydis	31.66	2.00e-77	282.00
IUUC-Vda-129723	Verticillium dahliae	35.71	4.00e-76	278.00
IUUC-Vpa-130284	Vicugna pacos	28.07	2.00e-31	129.00
IUUC-Vvi-131037	Vitis vinifera	90.27	0.00e+00	877.00
IUUC-Xtr-132235	Xenopus tropicalis	41.95	1.00e-109	389.00
IUUC-Xma-133840	Xiphophorus maculatus	41.42	8.00e-106	376.00
IUUC-Yli-134453	Yarrowia lipolytica	39.88	1.00e-87	316.00
IUUC-Zma-135669	Zea mays	58.80	3.00e-174	604.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence