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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018521
UUCD1 version UUC-CaE-00005
Ensembl Protein ID C27A12.8.1
UniProt Accession O01965; O01965_CAEEL
Genbank Protein ID CCD61206.1
Protein Name ARI (Ubiquitin ligase Ariadne) homolog
Genbank Nucleotide ID BX284601
Gene Name ari-1; C27A12.8; CELE_C27A12.8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00016158 C27A12.8.1 C27A12.8.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINA
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 19521497
Classification
Family E-value Score Start End
E3 activity/RBR 1.10e-42 146.8 128 313
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RBR
   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C+   s  el   l+C+h+ C++C+k yl+ ki ++ ++ei c+a++c+  +e+++++  ++++ +++ y+kl + ++ve+++ lkw
   Q: 128  CDICC---SLGELS-GLSCNHRACTQCWKAYLTNKIANNAQSEIECMAPNCKLLIEDEKVMFYITDPTVIATYRKLIVASYVETNRLLKW 213
           77776...333333.569************************************************************************ PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnhm 180
           cp  dC  +v++++  e   v c +cg  fC++C + wHe+++C+ lk +l+k++   +++e++++++an+k+CpkC ++iek++gCnhm
   Q: 214  CPGIDCGKAVRVSHW-EPRLVVC-SCGSRFCFSCGHDWHEPVNCRLLKLWLKKCN---DDSETSNWINANTKECPKCMITIEKDGGCNHM 298
           *************96.7777788.9******************************...99****************************** PP
   S: 181  tC..akCkaefCwlC 193
           tC  + C+ efCw+C
   Q: 299  TCknTACRFEFCWMC 313
           **7778********* PP
   
Organism Caenorhabditis elegans
Protein Sequence
(Fasta)
MSSDDEINMD DSDSSQGEID DGCMSDDDGI VLESREQNSS DYKDNGEPDN EVLNHDSLEA 60
EMKKTITDVQ AVLQVKTGVC RILLHKYKWN KESLLERFYE HPDTTTFLID AHVIPRRQER 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018521|E3,RING;E3,RBR|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTAGGTGCG CGACTGGCAG AAAATCGATA CATCAAATTG ATTTTTTTTG ATTGAGTGAA 60
TAATTGAGAA AAACTTTTAG AATGAGTTCC GACGATGAGA TCAATATGGA CGACAGTGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018521|E3,RING;E3,RBR|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF01485--IBR
SMART

SM00647--IBR
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0016874--F:ligase activity
GO:0046872--F:metal ion binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG cel:CELE_C27A12.8
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000970 Aegilops tauschii 30.13 7.00e-51 193.00
IUUC-Aml-001385 Ailuropoda melanoleuca 55.04 1.00e-138 484.00
IUUC-Atr-002480 Amborella trichopoda 31.03 1.00e-59 223.00
IUUC-Apl-004184 Anas platyrhynchos 56.78 8.00e-135 472.00
IUUC-Aca-004976 Anolis carolinensis 56.78 4.00e-135 473.00
IUUC-Aly-005807 Arabidopsis lyrata 31.21 1.00e-62 232.00
IUUC-Ath-007302 Arabidopsis thaliana 31.14 5.00e-62 230.00
IUUC-Ago-007926 Ashbya gossypii 29.09 1.00e-51 196.00
IUUC-Acl-008252 Aspergillus clavatus 42.33 5.00e-102 363.00
IUUC-Afl-008468 Aspergillus flavus 41.54 2.00e-101 361.00
IUUC-Afu-009062 Aspergillus fumigatus 41.98 3.00e-100 357.00
IUUC-Ani-009219 Aspergillus nidulans 42.22 5.00e-104 370.00
IUUC-Ang-009538 Aspergillus niger 42.23 6.00e-95 340.00
IUUC-Aor-010009 Aspergillus oryzae 41.54 1.00e-100 358.00
IUUC-Ate-010497 Aspergillus terreus 42.79 8.00e-95 339.00
IUUC-Ame-011264 Astyanax mexicanus 51.70 2.00e-146 511.00
IUUC-Bgr-012016 Blumeria graminis 42.54 6.00e-100 356.00
IUUC-Bta-013518 Bos taurus 55.04 1.00e-138 484.00
IUUC-Bci-013819 Botrytis cinerea 40.85 2.00e-101 361.00
IUUC-Bdi-014096 Brachypodium distachyon 31.08 1.00e-61 229.00
IUUC-Bol-016507 Brassica oleracea 30.61 4.00e-52 197.00
IUUC-Bra-018038 Brassica rapa 31.79 2.00e-54 206.00
IUUC-Cja-019869 Callithrix jacchus 49.23 3.00e-113 400.00
IUUC-Cfa-020812 Canis familiaris 55.04 2.00e-137 481.00
IUUC-Cpo-021627 Cavia porcellus 55.04 1.00e-138 484.00
IUUC-Cre-022815 Chlamydomonas reinhardtii 32.26 3.00e-58 218.00
IUUC-Csa-023034 Chlorocebus sabaeus 56.78 6.00e-135 472.00
IUUC-Cho-024444 Choloepus hoffmanni 53.95 3.00e-134 470.00
IUUC-Cin-025135 Ciona intestinalis 50.00 9.00e-135 472.00
IUUC-Csv-026243 Ciona savignyi 49.41 4.00e-132 463.00
IUUC-Cgl-026434 Colletotrichum gloeosporioides 43.76 8.00e-106 376.00
IUUC-Cne-026861 Cryptococcus neoformans 40.75 1.00e-97 349.00
IUUC-Dre-027785 Danio rerio 52.30 5.00e-148 516.00
IUUC-Dno-029205 Dasypus novemcinctus 55.04 1.00e-138 484.00
IUUC-Dor-030769 Dipodomys ordii 44.63 3.00e-100 357.00
IUUC-Dse-031171 Dothistroma septosporum 42.64 4.00e-99 353.00
IUUC-Dme-031903 Drosophila melanogaster 53.29 2.00e-146 511.00
IUUC-Eca-033431 Equus caballus 55.73 2.00e-137 480.00
IUUC-Eeu-034838 Erinaceus europaeus 46.73 5.00e-101 360.00
IUUC-Fca-035882 Felis catus 57.00 1.00e-121 427.00
IUUC-Fal-037068 Ficedula albicollis 55.96 2.00e-137 481.00
IUUC-Fox-037790 Fusarium oxysporum 52.57 2.00e-80 290.00
IUUC-Fso-038125 Fusarium solani 42.45 7.00e-103 366.00
IUUC-Gmo-038703 Gadus morhua 54.92 8.00e-147 512.00
IUUC-Ggr-039722 Gaeumannomyces graminis 43.42 3.00e-105 374.00
IUUC-Gga-040319 Gallus gallus 62.82 2.00e-124 437.00
IUUC-Gac-041708 Gasterosteus aculeatus 55.26 2.00e-146 511.00
IUUC-Gma-043188 Glycine max 30.04 1.00e-55 209.00
IUUC-Ggo-045178 Gorilla gorilla 55.04 1.00e-138 484.00
IUUC-Hsa-045718 Homo sapiens 55.04 1.00e-138 484.00
IUUC-Hvu-047322 Hordeum vulgare 30.70 9.00e-55 206.00
IUUC-Itr-048934 Ictidomys tridecemlineatus 65.58 3.00e-116 409.00
IUUC-Kpa-049350 Komagataella pastoris 33.18 8.00e-67 246.00
IUUC-Lpe-051110 Leersia perrieri 32.87 3.00e-65 241.00
IUUC-Loc-052442 Lepisosteus oculatus 51.70 1.00e-146 511.00
IUUC-Lma-053253 Leptosphaeria maculans 41.11 6.00e-104 370.00
IUUC-Laf-054351 Loxodonta africana 56.78 6.00e-135 472.00
IUUC-Mcc-054670 Macaca mulatta 53.29 2.00e-135 474.00
IUUC-Meu-056335 Macropus eugenii 60.65 6.00e-92 329.00
IUUC-Mor-057179 Magnaporthe oryzae 44.20 3.00e-104 370.00
IUUC-Mpo-057553 Magnaporthe poae 43.42 4.00e-106 377.00
IUUC-Mtr-058263 Medicago truncatula 30.26 2.00e-53 202.00
IUUC-Mla-058889 Melampsora laricipopulina 32.71 2.00e-71 261.00
IUUC-Mga-059385 Meleagris gallopavo 56.32 1.00e-135 475.00
IUUC-Mvi-060517 Microbotryum violaceum 41.00 2.00e-103 368.00
IUUC-Mmr-061439 Microcebus murinus 52.19 3.00e-123 434.00
IUUC-Mdo-062890 Monodelphis domestica 55.04 1.00e-138 485.00
IUUC-Mmu-063433 Mus musculus 55.04 1.00e-138 484.00
IUUC-Mac-064550 Musa acuminata 32.95 3.00e-64 238.00
IUUC-Mpu-066288 Mustela putorius furo 55.04 1.00e-138 485.00
IUUC-Mlu-067187 Myotis lucifugus 55.26 1.00e-138 484.00
IUUC-Nfi-068339 Neosartorya fischeri 42.11 2.00e-100 357.00
IUUC-Ncr-068947 Neurospora crassa 44.32 8.00e-101 359.00
IUUC-Nle-069263 Nomascus leucogenys 55.04 1.00e-138 484.00
IUUC-Ont-072309 Oreochromis niloticus 54.92 1.00e-146 511.00
IUUC-Oan-073731 Ornithorhynchus anatinus 57.04 8.00e-130 455.00
IUUC-Ocu-074000 Oryctolagus cuniculus 56.35 6.00e-135 472.00
IUUC-Oba-075628 Oryza barthii 31.31 7.00e-58 217.00
IUUC-Obr-076492 Oryza brachyantha 31.84 2.00e-64 239.00
IUUC-Ogl-077447 Oryza glaberrima 32.66 8.00e-66 243.00
IUUC-Ogu-078881 Oryza glumaepatula 32.51 8.00e-66 243.00
IUUC-Oin-079573 Oryza indica 32.33 5.00e-64 237.00
IUUC-Olo-080774 Oryza longistaminata 32.43 1.00e-65 243.00
IUUC-Ome-081470 Oryza meridionalis 30.71 5.00e-55 207.00
IUUC-Oni-082267 Oryza nivara 31.00 5.00e-58 217.00
IUUC-Opu-084135 Oryza punctata 32.66 7.00e-66 243.00
IUUC-Oru-084849 Oryza rufipogon 32.51 1.00e-65 243.00
IUUC-Osa-085435 Oryza sativa 32.29 3.00e-65 241.00
IUUC-Ola-086792 Oryzias latipes 54.92 2.00e-146 511.00
IUUC-Olu-087826 Ostreococcus lucimarinus 32.45 5.00e-45 174.00
IUUC-Oga-088706 Otolemur garnettii 55.04 1.00e-138 484.00
IUUC-Oar-089354 Ovis aries 54.82 3.00e-138 483.00
IUUC-Ptr-091287 Pan troglodytes 55.04 1.00e-138 484.00
IUUC-Pan-091701 Papio anubis 56.78 5.00e-135 473.00
IUUC-Psi-093814 Pelodiscus sinensis 56.78 7.00e-135 472.00
IUUC-Pma-094243 Petromyzon marinus 28.57 3.00e-47 182.00
IUUC-Pno-095124 Phaeosphaeria nodorum 33.94 7.00e-73 266.00
IUUC-Ppa-095554 Physcomitrella patens 29.08 9.00e-53 200.00
IUUC-Pfo-096449 Poecilia formosa 54.92 1.00e-146 511.00
IUUC-Pab-098132 Pongo abelii 55.04 1.00e-138 484.00
IUUC-Pop-099139 Populus trichocarpa 30.47 2.00e-55 209.00
IUUC-Pca-100303 Procavia capensis 63.72 5.00e-119 419.00
IUUC-Ppe-101451 Prunus persica 30.99 6.00e-52 197.00
IUUC-Pva-102457 Pteropus vampyrus 55.04 1.00e-138 484.00
IUUC-Pgr-103443 Puccinia graminis 38.22 6.00e-93 333.00
IUUC-Ptt-103795 Puccinia triticina 44.79 2.00e-85 308.00
IUUC-Pte-104022 Pyrenophora teres 40.04 2.00e-98 351.00
IUUC-Pyt-104643 Pyrenophora triticirepentis 41.01 1.00e-104 372.00
IUUC-Rno-106083 Rattus norvegicus 55.04 1.00e-138 484.00
IUUC-Sce-106154 Saccharomyces cerevisiae 30.95 6.00e-65 240.00
IUUC-Sha-106765 Sarcophilus harrisii 55.08 8.00e-136 475.00
IUUC-Sja-107977 Schizosaccharomyces japonicus 42.89 6.00e-105 373.00
IUUC-Spo-108222 Schizosaccharomyces pombe 42.67 2.00e-108 384.00
IUUC-Ssl-108406 Sclerotinia sclerotiorum 28.85 8.00e-14 70.50
IUUC-Smo-108845 Selaginella moellendorffii 31.38 4.00e-59 221.00
IUUC-Sit-110348 Setaria italica 31.60 5.00e-63 234.00
IUUC-Sly-111182 Solanum lycopersicum 31.42 2.00e-59 221.00
IUUC-Stu-112217 Solanum tuberosum 31.42 5.00e-59 220.00
IUUC-Sar-113023 Sorex araneus 56.54 5.00e-133 466.00
IUUC-Sbi-114262 Sorghum bicolor 31.24 1.00e-62 232.00
IUUC-Sre-115120 Sporisorium reilianum 43.93 1.00e-111 395.00
IUUC-Ssc-115667 Sus scrofa 54.14 1.00e-104 371.00
IUUC-Tgu-117273 Taeniopygia guttata 56.32 1.00e-135 474.00
IUUC-Tru-118338 Takifugu rubripes 54.57 4.00e-145 506.00
IUUC-Tsy-119096 Tarsius syrichta 52.57 2.00e-118 417.00
IUUC-Tni-120238 Tetraodon nigroviridis 54.92 2.00e-146 511.00
IUUC-Tca-121037 Theobroma cacao 32.70 4.00e-64 237.00
IUUC-Tre-121902 Trichoderma reesei 42.92 5.00e-103 366.00
IUUC-Tvi-122474 Trichoderma virens 42.20 4.00e-103 367.00
IUUC-Tae-124132 Triticum aestivum 31.87 3.00e-62 231.00
IUUC-Tur-126320 Triticum urartu 30.24 5.00e-53 200.00
IUUC-Tme-127089 Tuber melanosporum 43.05 5.00e-101 360.00
IUUC-Tbe-127409 Tupaia belangeri 67.33 3.00e-55 207.00
IUUC-Ttr-128909 Tursiops truncatus 48.03 5.00e-108 383.00
IUUC-Uma-129487 Ustilago maydis 43.74 4.00e-112 397.00
IUUC-Vda-129939 Verticillium dahliae 43.42 3.00e-104 370.00
IUUC-Vpa-130259 Vicugna pacos 53.29 2.00e-129 454.00
IUUC-Vvi-131463 Vitis vinifera 30.85 5.00e-58 217.00
IUUC-Xtr-132219 Xenopus tropicalis 55.04 5.00e-138 483.00
IUUC-Xma-133423 Xiphophorus maculatus 54.92 1.00e-146 511.00
IUUC-Yli-134622 Yarrowia lipolytica 33.47 2.00e-74 271.00
IUUC-Zma-135131 Zea mays 32.28 7.00e-62 230.00
Created Date 25-Jun-2017

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