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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-106083
UUCD1 version UUC-RaN-00325
Ensembl Protein ID ENSRNOP00000013581.5
UniProt Accession D3ZXL1; D3ZXL1_RAT
Genbank Protein ID ENSRNOP00000013581
Protein Name Ariadne RBR E3 ubiquitin protein ligase 1
Genbank Nucleotide ID AABR07070293
Gene Name Arih1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000009887.7 ENSRNOT00000013581.6 ENSRNOP00000013581.5
ENSRNOG00000009887.7 ENSRNOT00000084758.1 ENSRNOP00000075350.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status
Classification
Family E-Value Score Start End
E3 activity/RBR 1.70e-54 185.3 184 373
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RBR
   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelki.kegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalk 89
           C++C+l+++++ +t  leC h+fC++C+++yl++ki +eg+ ++iscpa+ c   ++++++++l+++++++ +y++l ++++ve+++ lk
   Q: 184  CQICYLNYPNSYFTG-LECGHKFCMQCWSEYLTTKImEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLK 272
           **********99985.5**************87775277899************************************************ PP
   S: 90   wcpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnh 179
           wcpapdC++vv ++   +++ v+c kcg++fC++C e+wH++++Ck+lk++ +k++   +++e++++++an+k+CpkC+v+iek++gCnh
   Q: 273  WCPAPDCHHVVKVQYP-DAKPVRC-KCGRQFCFNCGENWHDPVKCKWLKKWIKKCD---DDSETSNWIAANTKECPKCHVTIEKDGGCNH 357
           ***************7.9999999.9******************************...99***************************** PP
   S: 180  mtC..akCkaefCwlC 193
           m C  ++CkaefCw+C
   Q: 358  MVCrnQNCKAEFCWVC 373
           ***9999********* PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MDSDEGYNYE FDEDEECSEE DSGAEEEEDD DEDEPDDDNL DLGEVELVEP GLGVGGERDG 60
LLCGETGGGG GSALGPGGGG GGGGGGGGPG HEQEEDYRYE VLTAEQILQH MVECIREVNE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-106083|E3,RBR;E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGTTTTCCG TCCGAGCCCG GAGCGGAGCG GCGTCTGATT GAGGCCGGCA GTAAGCGGCC 60
CCCGCGCTCC CTCCCGCTCT GCTCCGCGCC CTCCCGGCCG CCGCCGCCGC CCGCCTCCAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-106083|E3,RBR;E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF01485--IBR
SMART

SM00647--IBR
SM00184--RING
Gene Ontology

GO:0031462--C:Cul2-RING ubiquitin ligase complex
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0097413--C:Lewy body
GO:0016604--C:nuclear body
GO:0019005--C:SCF ubiquitin ligase complex
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG rno:300756
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000970 Aegilops tauschii 29.78 2.00e-55 209.00
IUUC-Aml-001385 Ailuropoda melanoleuca 100.00 0.00e+00 927.00
IUUC-Atr-002480 Amborella trichopoda 31.85 8.00e-65 241.00
IUUC-Apl-004184 Anas platyrhynchos 98.42 0.00e+00 876.00
IUUC-Aca-004976 Anolis carolinensis 99.54 0.00e+00 877.00
IUUC-Aly-005807 Arabidopsis lyrata 32.37 2.00e-64 240.00
IUUC-Ath-007166 Arabidopsis thaliana 32.81 1.00e-64 241.00
IUUC-Ago-007926 Ashbya gossypii 29.37 2.00e-55 210.00
IUUC-Acl-008252 Aspergillus clavatus 42.49 2.00e-104 373.00
IUUC-Afl-008468 Aspergillus flavus 42.95 8.00e-106 377.00
IUUC-Afu-009062 Aspergillus fumigatus 44.69 2.00e-106 379.00
IUUC-Ani-009219 Aspergillus nidulans 42.73 1.00e-106 380.00
IUUC-Ang-009538 Aspergillus niger 43.29 1.00e-98 353.00
IUUC-Aor-010009 Aspergillus oryzae 42.95 4.00e-105 375.00
IUUC-Ate-010497 Aspergillus terreus 44.25 7.00e-99 354.00
IUUC-Ame-011264 Astyanax mexicanus 89.94 0.00e+00 961.00
IUUC-Bgr-012016 Blumeria graminis 41.19 3.00e-102 365.00
IUUC-Bta-013518 Bos taurus 100.00 0.00e+00 939.00
IUUC-Bci-013819 Botrytis cinerea 42.46 8.00e-107 380.00
IUUC-Bdi-014685 Brachypodium distachyon 32.59 3.00e-67 249.00
IUUC-Bol-016087 Brassica oleracea 31.94 1.00e-60 227.00
IUUC-Bra-017944 Brassica rapa 33.10 1.00e-55 211.00
IUUC-Cel-018521 Caenorhabditis elegans 55.04 4.00e-138 484.00
IUUC-Cja-019869 Callithrix jacchus 92.52 0.00e+00 845.00
IUUC-Cfa-020812 Canis familiaris 99.78 0.00e+00 932.00
IUUC-Cpo-021627 Cavia porcellus 100.00 0.00e+00 939.00
IUUC-Csa-023034 Chlorocebus sabaeus 100.00 0.00e+00 873.00
IUUC-Cho-024444 Choloepus hoffmanni 97.20 0.00e+00 905.00
IUUC-Cin-025135 Ciona intestinalis 69.11 0.00e+00 685.00
IUUC-Csv-026243 Ciona savignyi 68.39 0.00e+00 664.00
IUUC-Cgl-026434 Colletotrichum gloeosporioides 42.40 2.00e-107 382.00
IUUC-Cne-026861 Cryptococcus neoformans 41.98 4.00e-102 365.00
IUUC-Dre-027785 Danio rerio 90.14 0.00e+00 962.00
IUUC-Dno-029205 Dasypus novemcinctus 100.00 0.00e+00 939.00
IUUC-Dor-030769 Dipodomys ordii 82.18 0.00e+00 723.00
IUUC-Dse-031171 Dothistroma septosporum 42.46 2.00e-105 375.00
IUUC-Dme-031903 Drosophila melanogaster 70.35 0.00e+00 698.00
IUUC-Ete-032929 Echinops telfairi 84.30 1.00e-135 476.00
IUUC-Eca-033431 Equus caballus 99.78 0.00e+00 895.00
IUUC-Eeu-034838 Erinaceus europaeus 86.34 0.00e+00 753.00
IUUC-Fca-035882 Felis catus 95.88 0.00e+00 788.00
IUUC-Fal-037068 Ficedula albicollis 99.55 0.00e+00 895.00
IUUC-Fox-037790 Fusarium oxysporum 49.82 1.00e-77 282.00
IUUC-Fso-038125 Fusarium solani 42.25 2.00e-105 376.00
IUUC-Gmo-038703 Gadus morhua 90.35 0.00e+00 957.00
IUUC-Ggr-039722 Gaeumannomyces graminis 41.54 2.00e-105 375.00
IUUC-Gga-040319 Gallus gallus 100.00 0.00e+00 697.00
IUUC-Gac-041708 Gasterosteus aculeatus 96.73 0.00e+00 944.00
IUUC-Gma-043188 Glycine max 32.35 5.00e-60 225.00
IUUC-Ggo-045178 Gorilla gorilla 100.00 0.00e+00 939.00
IUUC-Hsa-045718 Homo sapiens 100.00 0.00e+00 939.00
IUUC-Hvu-047322 Hordeum vulgare 31.87 8.00e-59 221.00
IUUC-Itr-048934 Ictidomys tridecemlineatus 100.00 9.00e-178 615.00
IUUC-Kpa-049350 Komagataella pastoris 31.68 8.00e-65 241.00
IUUC-Lpe-051110 Leersia perrieri 33.18 4.00e-68 252.00
IUUC-Loc-052442 Lepisosteus oculatus 91.49 0.00e+00 972.00
IUUC-Lma-053253 Leptosphaeria maculans 42.83 1.00e-111 397.00
IUUC-Laf-054351 Loxodonta africana 100.00 0.00e+00 873.00
IUUC-Mcc-054670 Macaca mulatta 96.56 0.00e+00 927.00
IUUC-Meu-056335 Macropus eugenii 92.11 2.00e-142 498.00
IUUC-Mor-057179 Magnaporthe oryzae 42.00 1.00e-105 377.00
IUUC-Mpo-057553 Magnaporthe poae 41.33 2.00e-104 372.00
IUUC-Mtr-058263 Medicago truncatula 31.88 5.00e-58 218.00
IUUC-Mla-058889 Melampsora laricipopulina 36.76 4.00e-78 285.00
IUUC-Mga-059385 Meleagris gallopavo 98.21 0.00e+00 882.00
IUUC-Mvi-060517 Microbotryum violaceum 40.74 4.00e-105 375.00
IUUC-Mmr-061439 Microcebus murinus 93.38 0.00e+00 854.00
IUUC-Mdo-062890 Monodelphis domestica 99.78 0.00e+00 937.00
IUUC-Mmu-063433 Mus musculus 100.00 0.00e+00 939.00
IUUC-Mac-065341 Musa acuminata 33.79 2.00e-64 240.00
IUUC-Mpu-066288 Mustela putorius furo 100.00 0.00e+00 939.00
IUUC-Mlu-067187 Myotis lucifugus 99.78 0.00e+00 932.00
IUUC-Nfi-068339 Neosartorya fischeri 44.47 8.00e-106 377.00
IUUC-Ncr-068947 Neurospora crassa 43.53 3.00e-103 369.00
IUUC-Nle-069263 Nomascus leucogenys 100.00 0.00e+00 939.00
IUUC-Opr-071000 Ochotona princeps 100.00 1.00e-97 350.00
IUUC-Ont-072309 Oreochromis niloticus 96.53 0.00e+00 940.00
IUUC-Oan-073731 Ornithorhynchus anatinus 100.00 0.00e+00 831.00
IUUC-Ocu-074000 Oryctolagus cuniculus 98.19 0.00e+00 876.00
IUUC-Oba-075628 Oryza barthii 31.84 9.00e-62 231.00
IUUC-Obr-076492 Oryza brachyantha 32.74 2.00e-68 253.00
IUUC-Ogl-077447 Oryza glaberrima 33.18 6.00e-69 255.00
IUUC-Ogu-078881 Oryza glumaepatula 32.97 6.00e-69 255.00
IUUC-Oin-079573 Oryza indica 33.18 6.00e-67 248.00
IUUC-Olo-080774 Oryza longistaminata 33.19 2.00e-69 256.00
IUUC-Ome-081275 Oryza meridionalis 31.83 2.00e-61 229.00
IUUC-Oni-082267 Oryza nivara 31.83 2.00e-61 229.00
IUUC-Opu-084135 Oryza punctata 33.18 5.00e-69 255.00
IUUC-Oru-084849 Oryza rufipogon 32.97 1.00e-68 254.00
IUUC-Osa-085435 Oryza sativa 33.18 1.00e-68 254.00
IUUC-Ola-086792 Oryzias latipes 96.53 0.00e+00 939.00
IUUC-Olu-087826 Ostreococcus lucimarinus 32.90 3.00e-50 192.00
IUUC-Oga-088706 Otolemur garnettii 100.00 0.00e+00 939.00
IUUC-Oar-089354 Ovis aries 99.78 0.00e+00 937.00
IUUC-Ptr-091287 Pan troglodytes 100.00 0.00e+00 939.00
IUUC-Pan-091701 Papio anubis 100.00 0.00e+00 873.00
IUUC-Psi-093814 Pelodiscus sinensis 100.00 0.00e+00 873.00
IUUC-Pno-095124 Phaeosphaeria nodorum 35.71 6.00e-79 288.00
IUUC-Ppa-095545 Physcomitrella patens 32.44 2.00e-61 230.00
IUUC-Pfo-096449 Poecilia formosa 96.53 0.00e+00 940.00
IUUC-Pab-098132 Pongo abelii 100.00 0.00e+00 939.00
IUUC-Pop-099139 Populus trichocarpa 32.27 9.00e-64 238.00
IUUC-Pca-100303 Procavia capensis 99.70 0.00e+00 652.00
IUUC-Ppe-101740 Prunus persica 31.79 2.00e-59 223.00
IUUC-Pva-102457 Pteropus vampyrus 100.00 0.00e+00 939.00
IUUC-Pgr-103443 Puccinia graminis 42.53 7.00e-104 371.00
IUUC-Ptt-103795 Puccinia triticina 39.88 5.00e-93 335.00
IUUC-Pte-104022 Pyrenophora teres 40.77 5.00e-102 365.00
IUUC-Pyt-104643 Pyrenophora triticirepentis 42.37 7.00e-110 390.00
IUUC-Sce-106154 Saccharomyces cerevisiae 30.63 2.00e-64 239.00
IUUC-Sha-106765 Sarcophilus harrisii 97.75 0.00e+00 882.00
IUUC-Sja-107977 Schizosaccharomyces japonicus 43.59 1.00e-98 353.00
IUUC-Spo-108222 Schizosaccharomyces pombe 44.73 5.00e-111 394.00
IUUC-Smo-109078 Selaginella moellendorffii 32.71 5.00e-59 222.00
IUUC-Sit-110348 Setaria italica 32.14 8.00e-65 241.00
IUUC-Sly-111454 Solanum lycopersicum 32.79 2.00e-61 229.00
IUUC-Stu-112599 Solanum tuberosum 32.95 2.00e-58 220.00
IUUC-Sar-113023 Sorex araneus 99.77 0.00e+00 867.00
IUUC-Sbi-114262 Sorghum bicolor 32.81 2.00e-66 246.00
IUUC-Sre-115120 Sporisorium reilianum 44.80 2.00e-110 392.00
IUUC-Ssc-115667 Sus scrofa 89.47 0.00e+00 628.00
IUUC-Tgu-117273 Taeniopygia guttata 99.54 0.00e+00 873.00
IUUC-Tru-118338 Takifugu rubripes 86.76 0.00e+00 938.00
IUUC-Tsy-119096 Tarsius syrichta 91.67 0.00e+00 778.00
IUUC-Tni-120238 Tetraodon nigroviridis 86.69 0.00e+00 934.00
IUUC-Tca-121037 Theobroma cacao 33.33 2.00e-66 246.00
IUUC-Tre-121902 Trichoderma reesei 41.89 1.00e-103 370.00
IUUC-Tvi-122474 Trichoderma virens 41.19 5.00e-104 371.00
IUUC-Tae-124132 Triticum aestivum 33.11 1.00e-67 251.00
IUUC-Tur-126320 Triticum urartu 30.75 4.00e-55 209.00
IUUC-Tme-127089 Tuber melanosporum 42.92 2.00e-104 372.00
IUUC-Tbe-127409 Tupaia belangeri 93.09 9.00e-122 430.00
IUUC-Ttr-128909 Tursiops truncatus 90.85 0.00e+00 815.00
IUUC-Uma-129487 Ustilago maydis 42.49 4.00e-111 394.00
IUUC-Vda-129939 Verticillium dahliae 42.18 7.00e-106 377.00
IUUC-Vpa-130259 Vicugna pacos 96.77 0.00e+00 896.00
IUUC-Vvi-131463 Vitis vinifera 32.52 1.00e-58 221.00
IUUC-Xtr-132219 Xenopus tropicalis 99.13 0.00e+00 922.00
IUUC-Xma-133423 Xiphophorus maculatus 96.53 0.00e+00 940.00
IUUC-Yli-134622 Yarrowia lipolytica 35.65 2.00e-73 270.00
IUUC-Zma-135131 Zea mays 33.11 9.00e-67 248.00
Created Date 25-Jun-2017

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