iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008804

Ensembl Protein ID

CADAFUAP00002861

UniProt Accession

Q4WEJ7; Q4WEJ7_ASPFU

Genbank Protein ID

EAL85980.1

Protein Name

Ubiquitin C-terminal hydrolase (HAUSP), putative

Genbank Nucleotide ID

AAHF01000011

Gene Name

AFUA_5G03250

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00002861	CADAFUAT00002861	CADAFUAP00002861

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.90e-70	235.3	218	540

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaq 93
           +GlkN+g+tCY+NS+LQ+L++++ +r+++ +  + + +      +  + + +lq+lf +l ++++++vs++el++++++e+++   +eqqD+q
   Q: 218  VGLKNQGATCYLNSLLQSLYFTNAFRKAVYQ-IPTEAE-----ATRDNSAWTLQRLFYNL-QTSESSVSTTELTASFGWESRQ--IFEQQDVQ 301
           6******************************.444433.....345577899********.99999****************9..79****** PP
   S: 94   EflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkes 186
           E+ + l+++lee++                          k +  ++ +  lF g++k+ i c + d +ssr e+f+d++l+v+g++     +
   Q: 302  ELSRKLMERLEEKM--------------------------KATPVEKALPGLFVGKTKTYISCINVDYESSRVEDFWDIQLNVRGNK-----T 363
           **************..........................6788899999*************************************.....9 PP
   S: 187  lqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYe 279
           l+d+++++ + e+legenky   + +++q+a+k + ++++P+vL+lhLkRf+++ +++   kin++  fp e+d +p++++  +k+ e+ +Y+
   Q: 364  LDDSFKDYIQVETLEGENKYDAGSPYGLQDAKKGVIFESFPPVLHLHLKRFEYDINRDAMMKINDRHAFPMEFDATPYLSDAADKS-EPWIYQ 455
           *********************************************************************************77665.7***** PP
   S: 280  LiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg..........................staYvlfYkr 337
           L++v+vHsG l+ GHY+a+ k +k++ W++fdD++Vt  + +evlee+                            +aY+l+Y r
   Q: 456  LHGVLVHSGDLNAGHYYAFLKPTKDGhWFKFDDDRVTRATDKEVLEENYggeyelsngaagvrqphtrglstkrsMNAYMLVYIR 540
           *********************977667*******************8779*********************************87 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MDNVADNEML VDEYEQYHND RTDDVVVSRS GSEEPEPEPL ADDFTAMMAR ILPKDPDLET 60
ADEAYHTWHI QDWRKLKKKE HGPIFQCGGF PWRVLFFPYG NHVDYASFYL EHAWEKEPPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAACG TCAGTGCCCC GTTCATTTCT GCCTCCGCAT GAGAGAGGAG AGTAACGATC 60
CAGAGTCGCT GAAACATTGC TTATCAATAT CTAACATGTG TACTTTCGTC ATATAGGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR029071--Ubiquitin-rel_dom
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

afm:AFUA_5G03250

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	36.67	2.00e-150	525.00
IUUC-Aml-002408	Ailuropoda melanoleuca	35.27	5.00e-164	570.00
IUUC-Atr-003067	Amborella trichopoda	37.49	2.00e-120	425.00
IUUC-Apl-003558	Anas platyrhynchos	35.53	2.00e-171	595.00
IUUC-Aca-004518	Anolis carolinensis	34.35	3.00e-162	564.00
IUUC-Aly-006453	Arabidopsis lyrata	38.39	6.00e-168	583.00
IUUC-Ath-006591	Arabidopsis thaliana	38.99	3.00e-164	570.00
IUUC-Ago-007849	Ashbya gossypii	37.51	0.00e+00	640.00
IUUC-Acl-008327	Aspergillus clavatus	91.45	0.00e+00	2143.00
IUUC-Afl-008491	Aspergillus flavus	87.80	0.00e+00	2027.00
IUUC-Ang-009776	Aspergillus niger	88.65	0.00e+00	1977.00
IUUC-Aor-009998	Aspergillus oryzae	86.11	0.00e+00	1986.00
IUUC-Ate-010428	Aspergillus terreus	88.07	0.00e+00	2024.00
IUUC-Ame-010903	Astyanax mexicanus	35.42	5.00e-172	597.00
IUUC-Bgr-012132	Blumeria graminis	50.13	0.00e+00	1093.00
IUUC-Bta-013192	Bos taurus	35.37	2.00e-164	571.00
IUUC-Bci-013924	Botrytis cinerea	51.64	0.00e+00	1132.00
IUUC-Bdi-015069	Brachypodium distachyon	38.21	4.00e-161	560.00
IUUC-Bol-016286	Brassica oleracea	39.04	2.00e-163	568.00
IUUC-Bra-016714	Brassica rapa	38.85	3.00e-162	564.00
IUUC-Cel-018219	Caenorhabditis elegans	28.02	3.00e-99	355.00
IUUC-Cja-019006	Callithrix jacchus	35.28	9.00e-165	572.00
IUUC-Cfa-020361	Canis familiaris	35.27	4.00e-164	570.00
IUUC-Cpo-022320	Cavia porcellus	35.37	3.00e-164	571.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	43.55	2.00e-96	344.00
IUUC-Csa-024050	Chlorocebus sabaeus	35.27	6.00e-164	569.00
IUUC-Cho-024434	Choloepus hoffmanni	32.96	2.00e-99	355.00
IUUC-Cin-025689	Ciona intestinalis	34.92	4.00e-159	553.00
IUUC-Csv-025963	Ciona savignyi	32.86	2.00e-150	525.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	53.20	0.00e+00	1147.00
IUUC-Cne-026968	Cryptococcus neoformans	47.09	0.00e+00	974.00
IUUC-Cme-027103	Cyanidioschyzon merolae	39.22	1.00e-109	390.00
IUUC-Dre-028510	Danio rerio	35.51	3.00e-173	600.00
IUUC-Dno-029696	Dasypus novemcinctus	35.37	4.00e-163	567.00
IUUC-Dor-030611	Dipodomys ordii	43.93	4.00e-69	254.00
IUUC-Dse-031433	Dothistroma septosporum	52.13	0.00e+00	1137.00
IUUC-Dme-031583	Drosophila melanogaster	32.99	5.00e-153	533.00
IUUC-Ete-033191	Echinops telfairi	35.31	2.00e-158	551.00
IUUC-Eca-034122	Equus caballus	35.56	3.00e-165	574.00
IUUC-Eeu-035292	Erinaceus europaeus	35.76	4.00e-56	211.00
IUUC-Fca-036377	Felis catus	35.27	6.00e-164	570.00
IUUC-Fal-036964	Ficedula albicollis	35.04	5.00e-173	600.00
IUUC-Fox-037695	Fusarium oxysporum	53.32	0.00e+00	1182.00
IUUC-Fso-038084	Fusarium solani	51.67	0.00e+00	1141.00
IUUC-Gmo-038644	Gadus morhua	35.66	4.00e-174	603.00
IUUC-Ggr-040029	Gaeumannomyces graminis	49.83	0.00e+00	1104.00
IUUC-Gga-040944	Gallus gallus	35.60	1.00e-172	598.00
IUUC-Gac-041740	Gasterosteus aculeatus	35.66	1.00e-173	602.00
IUUC-Gma-043300	Glycine max	37.67	1.00e-176	612.00
IUUC-Ggo-044947	Gorilla gorilla	35.27	4.00e-164	570.00
IUUC-Hsa-046278	Homo sapiens	35.27	6.00e-164	569.00
IUUC-Hvu-047749	Hordeum vulgare	39.12	1.00e-149	522.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	37.33	5.00e-156	543.00
IUUC-Kpa-049121	Komagataella pastoris	36.83	0.00e+00	660.00
IUUC-Lch-049847	Latimeria chalumnae	35.22	3.00e-175	607.00
IUUC-Lpe-051505	Leersia perrieri	37.15	5.00e-152	530.00
IUUC-Loc-052234	Lepisosteus oculatus	38.52	3.00e-144	504.00
IUUC-Lma-053169	Leptosphaeria maculans	56.20	0.00e+00	1303.00
IUUC-Laf-053566	Loxodonta africana	35.37	3.00e-164	570.00
IUUC-Mcc-055549	Macaca mulatta	35.27	5.00e-164	570.00
IUUC-Meu-056887	Macropus eugenii	29.60	4.00e-78	284.00
IUUC-Mor-057149	Magnaporthe oryzae	51.36	0.00e+00	1116.00
IUUC-Mpo-057536	Magnaporthe poae	50.87	0.00e+00	1108.00
IUUC-Mtr-058583	Medicago truncatula	39.30	3.00e-167	580.00
IUUC-Mla-058899	Melampsora laricipopulina	45.28	0.00e+00	919.00
IUUC-Mga-060148	Meleagris gallopavo	35.49	8.00e-173	599.00
IUUC-Mvi-060207	Microbotryum violaceum	46.92	0.00e+00	947.00
IUUC-Mmr-060946	Microcebus murinus	35.27	3.00e-164	570.00
IUUC-Mdo-062079	Monodelphis domestica	36.31	1.00e-151	529.00
IUUC-Mmu-063678	Mus musculus	35.47	7.00e-164	569.00
IUUC-Mac-064796	Musa acuminata	37.43	6.00e-159	553.00
IUUC-Mpu-066744	Mustela putorius furo	35.07	2.00e-163	567.00
IUUC-Mlu-067949	Myotis lucifugus	35.37	5.00e-164	570.00
IUUC-Nfi-068342	Neosartorya fischeri	98.29	0.00e+00	2156.00
IUUC-Ncr-068818	Neurospora crassa	53.40	0.00e+00	1149.00
IUUC-Nle-070064	Nomascus leucogenys	35.27	6.00e-164	570.00
IUUC-Opr-071001	Ochotona princeps	36.33	4.00e-144	504.00
IUUC-Ont-072095	Oreochromis niloticus	35.32	8.00e-171	592.00
IUUC-Oan-073483	Ornithorhynchus anatinus	35.36	7.00e-164	569.00
IUUC-Ocu-073967	Oryctolagus cuniculus	35.60	3.00e-162	564.00
IUUC-Oba-075811	Oryza barthii	36.86	6.00e-152	530.00
IUUC-Obr-076857	Oryza brachyantha	38.86	4.00e-161	560.00
IUUC-Ogl-077038	Oryza glaberrima	38.71	7.00e-160	556.00
IUUC-Ogu-078265	Oryza glumaepatula	36.98	1.00e-145	509.00
IUUC-Oin-079513	Oryza indica	38.22	8.00e-158	549.00
IUUC-Olo-081067	Oryza longistaminata	36.65	5.00e-152	530.00
IUUC-Ome-081879	Oryza meridionalis	37.73	6.00e-157	546.00
IUUC-Oni-082461	Oryza nivara	36.26	6.00e-149	520.00
IUUC-Opu-083199	Oryza punctata	37.84	5.00e-157	546.00
IUUC-Oru-085109	Oryza rufipogon	37.44	3.00e-152	530.00
IUUC-Osa-085418	Oryza sativa	37.44	5.00e-146	510.00
IUUC-Ola-086640	Oryzias latipes	35.56	1.00e-172	598.00
IUUC-Olu-087874	Ostreococcus lucimarinus	32.87	4.00e-137	480.00
IUUC-Oga-089059	Otolemur garnettii	32.29	1.00e-137	482.00
IUUC-Oar-089710	Ovis aries	35.37	2.00e-164	571.00
IUUC-Ptr-091334	Pan troglodytes	35.27	4.00e-164	570.00
IUUC-Pan-091717	Papio anubis	35.17	6.00e-164	570.00
IUUC-Psi-093933	Pelodiscus sinensis	35.39	6.00e-170	590.00
IUUC-Pma-094648	Petromyzon marinus	37.25	2.00e-163	568.00
IUUC-Pno-095020	Phaeosphaeria nodorum	55.20	0.00e+00	1157.00
IUUC-Ppa-095922	Physcomitrella patens	39.85	1.00e-172	599.00
IUUC-Pfo-096181	Poecilia formosa	35.42	8.00e-172	596.00
IUUC-Pab-098231	Pongo abelii	33.62	5.00e-150	523.00
IUUC-Pop-099680	Populus trichocarpa	36.91	3.00e-163	567.00
IUUC-Pca-100543	Procavia capensis	34.55	4.00e-88	318.00
IUUC-Ppe-101847	Prunus persica	37.83	8.00e-159	553.00
IUUC-Pva-102472	Pteropus vampyrus	35.17	3.00e-157	547.00
IUUC-Pgr-103463	Puccinia graminis	44.75	0.00e+00	912.00
IUUC-Ptt-103716	Puccinia triticina	44.65	0.00e+00	861.00
IUUC-Pte-104360	Pyrenophora teres	57.21	0.00e+00	1228.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	57.12	0.00e+00	1224.00
IUUC-Rno-105816	Rattus norvegicus	35.47	9.00e-165	572.00
IUUC-Sce-106230	Saccharomyces cerevisiae	33.25	6.00e-163	566.00
IUUC-Sha-107439	Sarcophilus harrisii	35.00	6.00e-165	573.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	41.09	0.00e+00	788.00
IUUC-Spo-108019	Schizosaccharomyces pombe	43.69	0.00e+00	787.00
IUUC-Smo-109308	Selaginella moellendorffii	37.66	7.00e-164	569.00
IUUC-Sit-110268	Setaria italica	37.95	5.00e-161	560.00
IUUC-Sly-111774	Solanum lycopersicum	38.92	1.00e-169	588.00
IUUC-Stu-112387	Solanum tuberosum	38.73	1.00e-170	592.00
IUUC-Sar-113685	Sorex araneus	35.17	2.00e-161	561.00
IUUC-Sbi-114424	Sorghum bicolor	38.39	2.00e-160	558.00
IUUC-Sre-115156	Sporisorium reilianum	48.93	0.00e+00	963.00
IUUC-Ssc-116297	Sus scrofa	35.37	3.00e-164	570.00
IUUC-Tgu-116767	Taeniopygia guttata	35.07	2.00e-171	594.00
IUUC-Tru-118208	Takifugu rubripes	35.66	3.00e-169	587.00
IUUC-Tsy-119277	Tarsius syrichta	38.54	2.00e-57	216.00
IUUC-Tni-119890	Tetraodon nigroviridis	35.52	9.00e-167	579.00
IUUC-Tca-121630	Theobroma cacao	38.10	1.00e-162	565.00
IUUC-Tre-122169	Trichoderma reesei	52.75	0.00e+00	1121.00
IUUC-Tvi-122600	Trichoderma virens	53.55	0.00e+00	1160.00
IUUC-Tae-125264	Triticum aestivum	37.70	5.00e-159	553.00
IUUC-Tur-126287	Triticum urartu	35.37	5.00e-157	546.00
IUUC-Tme-127045	Tuber melanosporum	57.29	0.00e+00	1243.00
IUUC-Tbe-127861	Tupaia belangeri	34.00	5.00e-48	185.00
IUUC-Ttr-129161	Tursiops truncatus	35.27	3.00e-162	563.00
IUUC-Uma-129535	Ustilago maydis	49.25	0.00e+00	979.00
IUUC-Vda-129708	Verticillium dahliae	53.17	0.00e+00	1166.00
IUUC-Vpa-130141	Vicugna pacos	32.93	1.00e-50	194.00
IUUC-Vvi-130882	Vitis vinifera	37.61	4.00e-161	560.00
IUUC-Xtr-132073	Xenopus tropicalis	35.47	4.00e-169	587.00
IUUC-Xma-133949	Xiphophorus maculatus	35.45	1.00e-171	595.00
IUUC-Yli-134527	Yarrowia lipolytica	43.18	0.00e+00	791.00
IUUC-Zma-135855	Zea mays	38.33	8.00e-162	563.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence