iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033380

UUCD1 version

UUC-EqC-01065

Ensembl Protein ID

ENSECAP00000016122.1

UniProt Accession

F7AAM2; F7AAM2_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018570.1	ENSECAT00000019683.1	ENSECAP00000016122.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-68	232.2	411	789

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 411  GLINKGNWCYINATLQALVACPPMYHLMKF-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 497
           9***************************99.333333.334799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.............eknkpkeeeeeedkselsde...............ae 131
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+ +              +n pk+++ +ed++e +de               + 
   Q: 498  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkkllspsnekltISNGPKSHSVNEDEQEEPDEgsedeweqvgprnktSV 586
           *9999999999966599********************4456688888888885555555555555555555566776777766644444 PP
   S: 132  ekkkkknk...slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqea 217
            ++    +   ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k k+++e 
   Q: 587  TRQA---DfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKTKQEVEI 664
           4444...1555***********9.688999999*******************99...****************8....99999****** PP
   S: 218  ekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYvayvkne 302
           +++++l+klP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY+++v + 
   Q: 665  SRRVTLEKLPPVLVLHLKRFVYEKTGGCQ-KLVKNIEYPVDLEISKELLSPGVKNKNlkcHRTYRLFAVVYHHGsSATGGHYTTDVFQI 752
           **********************9998886.***************9999977776667779***************************8 PP
   S: 303  kgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
             + Wl++dD+ V++v++ +v++ t+ +taY+l+Y+r
   Q: 753  GLNgWLRIDDQMVKVVNQYQVVKPTAdRTAYLLYYRR 789
           7777*******************9989********98 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

QYIFGDFSPD EFNQFFVAPR CSVELPPYNG TVLCGVQAAD DLPDGQEYQR IEFGVNEVIE 60
SNGALPRTPN YSISSTLNPQ APEFILSCTA STKTPDDPDK EANYSSTDCP DPGSALALDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTATATTT TTGGAGATTT TAGCCCTGAC GAATTCAATC AGTTCTTTGT GGCCCCTCGC 60
TGTTCAGTTG AGGTAAGACA AAGCTTTGTT TTATTGAGTA TATGTGTAGA TAGAATCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	30.56	2.00e-46	180.00
IUUC-Aml-001584	Ailuropoda melanoleuca	89.91	0.00e+00	1346.00
IUUC-Atr-002927	Amborella trichopoda	35.73	1.00e-59	224.00
IUUC-Apl-003988	Anas platyrhynchos	78.74	0.00e+00	1172.00
IUUC-Aca-004461	Anolis carolinensis	87.72	1.00e-163	568.00
IUUC-Aly-006038	Arabidopsis lyrata	36.15	9.00e-57	214.00
IUUC-Ath-007328	Arabidopsis thaliana	35.90	4.00e-55	208.00
IUUC-Ago-007717	Ashbya gossypii	30.13	4.00e-45	176.00
IUUC-Acl-008188	Aspergillus clavatus	33.48	3.00e-64	240.00
IUUC-Afl-008456	Aspergillus flavus	39.38	3.00e-50	192.00
IUUC-Afu-009067	Aspergillus fumigatus	36.41	2.00e-67	250.00
IUUC-Ani-009483	Aspergillus nidulans	33.26	8.00e-62	231.00
IUUC-Ang-009639	Aspergillus niger	35.25	1.00e-60	227.00
IUUC-Aor-010040	Aspergillus oryzae	36.39	2.00e-62	233.00
IUUC-Ate-010310	Aspergillus terreus	34.29	1.00e-62	234.00
IUUC-Ame-011012	Astyanax mexicanus	74.94	9.00e-169	587.00
IUUC-Bgr-012311	Blumeria graminis	34.86	3.00e-45	176.00
IUUC-Bta-013299	Bos taurus	89.67	0.00e+00	1304.00
IUUC-Bci-013783	Botrytis cinerea	37.11	2.00e-58	221.00
IUUC-Bdi-015039	Brachypodium distachyon	32.52	2.00e-50	193.00
IUUC-Bol-015806	Brassica oleracea	37.69	1.00e-64	240.00
IUUC-Bra-017076	Brassica rapa	37.69	1.00e-64	240.00
IUUC-Cja-018715	Callithrix jacchus	86.38	0.00e+00	1318.00
IUUC-Cfa-020194	Canis familiaris	90.79	0.00e+00	1368.00
IUUC-Cpo-022272	Cavia porcellus	72.61	0.00e+00	1015.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	33.55	1.00e-34	141.00
IUUC-Csa-023310	Chlorocebus sabaeus	87.89	0.00e+00	1342.00
IUUC-Cho-024966	Choloepus hoffmanni	76.51	0.00e+00	935.00
IUUC-Cin-025616	Ciona intestinalis	44.56	5.00e-107	381.00
IUUC-Csv-026043	Ciona savignyi	46.85	2.00e-100	358.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	34.40	3.00e-47	183.00
IUUC-Cne-026962	Cryptococcus neoformans	35.79	2.00e-51	197.00
IUUC-Cme-027113	Cyanidioschyzon merolae	31.38	9.00e-40	158.00
IUUC-Dre-028072	Danio rerio	77.42	0.00e+00	728.00
IUUC-Dno-029489	Dasypus novemcinctus	87.52	0.00e+00	1368.00
IUUC-Dor-031068	Dipodomys ordii	74.53	3.00e-144	505.00
IUUC-Dse-031553	Dothistroma septosporum	36.08	8.00e-57	215.00
IUUC-Dme-031759	Drosophila melanogaster	42.69	8.00e-85	309.00
IUUC-Ete-032549	Echinops telfairi	77.46	0.00e+00	882.00
IUUC-Eeu-034818	Erinaceus europaeus	86.13	0.00e+00	1299.00
IUUC-Fca-035535	Felis catus	88.66	0.00e+00	1244.00
IUUC-Fal-036627	Ficedula albicollis	76.57	0.00e+00	1125.00
IUUC-Fox-037904	Fusarium oxysporum	36.59	5.00e-54	206.00
IUUC-Fso-038170	Fusarium solani	32.95	1.00e-52	201.00
IUUC-Gmo-039499	Gadus morhua	69.64	0.00e+00	668.00
IUUC-Ggr-040042	Gaeumannomyces graminis	35.90	2.00e-62	234.00
IUUC-Gga-040571	Gallus gallus	78.84	0.00e+00	1164.00
IUUC-Gac-041345	Gasterosteus aculeatus	75.65	0.00e+00	661.00
IUUC-Gma-044407	Glycine max	35.13	4.00e-59	222.00
IUUC-Ggo-044652	Gorilla gorilla	88.15	0.00e+00	1364.00
IUUC-Hsa-045864	Homo sapiens	88.40	0.00e+00	1370.00
IUUC-Hvu-047071	Hordeum vulgare	33.00	1.00e-53	203.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	89.54	0.00e+00	1016.00
IUUC-Kpa-049132	Komagataella pastoris	30.72	6.00e-47	182.00
IUUC-Lch-050040	Latimeria chalumnae	70.84	0.00e+00	932.00
IUUC-Loc-052449	Lepisosteus oculatus	74.12	0.00e+00	714.00
IUUC-Lma-053248	Leptosphaeria maculans	35.88	7.00e-59	222.00
IUUC-Laf-054121	Loxodonta africana	86.89	0.00e+00	1332.00
IUUC-Mcc-055514	Macaca mulatta	87.89	0.00e+00	1344.00
IUUC-Meu-056873	Macropus eugenii	73.00	0.00e+00	852.00
IUUC-Mor-057243	Magnaporthe oryzae	33.93	1.00e-58	221.00
IUUC-Mpo-057439	Magnaporthe poae	35.62	2.00e-61	231.00
IUUC-Mtr-058457	Medicago truncatula	34.36	2.00e-57	216.00
IUUC-Mla-058929	Melampsora laricipopulina	31.84	2.00e-58	220.00
IUUC-Mga-060157	Meleagris gallopavo	77.16	0.00e+00	1164.00
IUUC-Mvi-060442	Microbotryum violaceum	32.51	3.00e-53	204.00
IUUC-Mmr-061062	Microcebus murinus	87.12	0.00e+00	1344.00
IUUC-Mdo-062798	Monodelphis domestica	80.71	0.00e+00	1212.00
IUUC-Mmu-064050	Mus musculus	80.96	0.00e+00	1243.00
IUUC-Mac-065202	Musa acuminata	34.26	2.00e-51	196.00
IUUC-Mpu-066554	Mustela putorius furo	89.55	0.00e+00	1326.00
IUUC-Mlu-068003	Myotis lucifugus	89.79	0.00e+00	1370.00
IUUC-Nfi-068612	Neosartorya fischeri	35.90	8.00e-65	241.00
IUUC-Ncr-068878	Neurospora crassa	35.40	3.00e-52	200.00
IUUC-Nle-069661	Nomascus leucogenys	88.02	0.00e+00	1346.00
IUUC-Opr-070944	Ochotona princeps	80.87	4.00e-172	597.00
IUUC-Ont-071266	Oreochromis niloticus	58.41	0.00e+00	805.00
IUUC-Oan-073442	Ornithorhynchus anatinus	79.20	0.00e+00	1137.00
IUUC-Ocu-073788	Oryctolagus cuniculus	79.44	0.00e+00	1114.00
IUUC-Oba-075085	Oryza barthii	34.53	2.00e-38	152.00
IUUC-Obr-076663	Oryza brachyantha	32.91	7.00e-47	181.00
IUUC-Ogl-076937	Oryza glaberrima	30.63	2.00e-49	189.00
IUUC-Ogu-078909	Oryza glumaepatula	31.01	1.00e-47	184.00
IUUC-Oin-079617	Oryza indica	32.04	6.00e-49	189.00
IUUC-Olo-081043	Oryza longistaminata	26.56	1.00e-25	111.00
IUUC-Ome-081646	Oryza meridionalis	25.52	2.00e-24	107.00
IUUC-Oni-082914	Oryza nivara	31.01	1.00e-47	184.00
IUUC-Oru-084878	Oryza rufipogon	31.01	1.00e-47	184.00
IUUC-Osa-085822	Oryza sativa	31.52	1.00e-51	197.00
IUUC-Ola-086931	Oryzias latipes	58.96	0.00e+00	797.00
IUUC-Oga-088443	Otolemur garnettii	86.51	0.00e+00	1340.00
IUUC-Oar-089325	Ovis aries	87.28	0.00e+00	1211.00
IUUC-Ptr-091584	Pan troglodytes	85.37	0.00e+00	1274.00
IUUC-Pan-092551	Papio anubis	86.00	0.00e+00	1306.00
IUUC-Psi-093366	Pelodiscus sinensis	75.14	0.00e+00	707.00
IUUC-Pno-095136	Phaeosphaeria nodorum	35.33	5.00e-53	202.00
IUUC-Ppa-095574	Physcomitrella patens	35.76	2.00e-59	223.00
IUUC-Pfo-097462	Poecilia formosa	76.82	0.00e+00	695.00
IUUC-Pab-098547	Pongo abelii	88.15	0.00e+00	1344.00
IUUC-Pop-099529	Populus trichocarpa	37.18	2.00e-62	233.00
IUUC-Pca-101066	Procavia capensis	77.40	0.00e+00	1157.00
IUUC-Ppe-102110	Prunus persica	36.90	3.00e-60	225.00
IUUC-Pva-103015	Pteropus vampyrus	85.26	0.00e+00	1285.00
IUUC-Ptt-103998	Puccinia triticina	33.09	1.00e-53	204.00
IUUC-Pte-104417	Pyrenophora teres	34.51	4.00e-55	209.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	35.71	4.00e-55	209.00
IUUC-Rno-105533	Rattus norvegicus	81.74	0.00e+00	1249.00
IUUC-Sce-106160	Saccharomyces cerevisiae	27.19	1.00e-37	152.00
IUUC-Sha-106590	Sarcophilus harrisii	80.20	0.00e+00	1202.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	36.61	2.00e-57	216.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.47	5.00e-66	244.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	36.55	3.00e-58	219.00
IUUC-Smo-109645	Selaginella moellendorffii	36.92	7.00e-39	153.00
IUUC-Sit-110781	Setaria italica	31.97	9.00e-57	214.00
IUUC-Sly-111797	Solanum lycopersicum	34.02	3.00e-55	209.00
IUUC-Stu-112188	Solanum tuberosum	34.68	4.00e-55	209.00
IUUC-Sbi-114862	Sorghum bicolor	33.06	3.00e-46	179.00
IUUC-Sre-115162	Sporisorium reilianum	35.67	5.00e-68	252.00
IUUC-Ssc-115505	Sus scrofa	95.47	5.00e-166	576.00
IUUC-Tgu-116535	Taeniopygia guttata	76.42	0.00e+00	1136.00
IUUC-Tru-117542	Takifugu rubripes	57.18	0.00e+00	828.00
IUUC-Tni-120200	Tetraodon nigroviridis	58.75	0.00e+00	827.00
IUUC-Tca-121548	Theobroma cacao	35.24	6.00e-45	175.00
IUUC-Tre-122124	Trichoderma reesei	34.46	4.00e-61	229.00
IUUC-Tvi-122457	Trichoderma virens	34.79	6.00e-55	209.00
IUUC-Tae-125646	Triticum aestivum	33.92	8.00e-57	215.00
IUUC-Tme-127180	Tuber melanosporum	39.52	3.00e-71	263.00
IUUC-Tbe-127530	Tupaia belangeri	73.94	0.00e+00	1032.00
IUUC-Ttr-128549	Tursiops truncatus	81.70	0.00e+00	1228.00
IUUC-Uma-129381	Ustilago maydis	33.82	3.00e-67	250.00
IUUC-Vda-129889	Verticillium dahliae	32.11	3.00e-52	200.00
IUUC-Vpa-130100	Vicugna pacos	83.00	0.00e+00	1243.00
IUUC-Vvi-131366	Vitis vinifera	36.64	2.00e-64	239.00
IUUC-Xtr-132048	Xenopus tropicalis	63.83	0.00e+00	936.00
IUUC-Xma-133593	Xiphophorus maculatus	77.68	0.00e+00	689.00
IUUC-Yli-134338	Yarrowia lipolytica	27.29	3.00e-33	136.00
IUUC-Zma-135586	Zea mays	28.95	9.00e-50	191.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence