iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.30e-09	37.2	1114	1162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           + C++C+++g+ e ++v C+ C++  H  C+ ++  +++p+ + w+Cp+Cr 
   Q: 1114 ARCKICRKKGDAE-NMVLCDGCDRGHHTYCVRPK-LKTVPDGD-WFCPECRP 1162
           57*********98.6*******************.*******7.******96 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

LFHHINDFFE RTILCNSLVW SCAVTGRPGL TYQEALESER KAKQDLQSFP EPLIIPVLYL 60
TNLTHRSRLH EICDDIFAYI KDRYFVEETV EVIRNNGTRL QCRILEVLPP LHQNGFANGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTTCATC ACATAAAATA ATTCGTTTTC TCTTATTGTT AGGTGCCCAG ATTGATTTTT 60
CTACTATTAA GGTTTTTATA AAAAGCCATG GTTAATTTGA CATTAGTGTT GTGCCTTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR018501--DDT_dom
IPR029063--SAM-dependent_MTases
IPR028942--WHIM1_dom
IPR028941--WHIM2_dom
IPR013136--WSTF_Acf1_Cbp146
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50827--DDT
PS51136--WAC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF02791--DDT
PF00628--PHD
PF10537--WAC_Acf1_DNA_bd
PF15612--WHIM1
PF15613--WSD

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00571--DDT
SM00249--PHD

Gene Ontology

GO:0008623--C:CHRAC
GO:0008270--F:zinc ion binding
GO:0006261--P:DNA-dependent DNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002389	Ailuropoda melanoleuca	86.95	0.00e+00	2242.00
IUUC-Apl-004078	Anas platyrhynchos	73.25	0.00e+00	1907.00
IUUC-Aca-004951	Anolis carolinensis	70.66	0.00e+00	1335.00
IUUC-Bta-012850	Bos taurus	87.18	0.00e+00	2036.00
IUUC-Cel-018523	Caenorhabditis elegans	46.38	4.00e-16	81.30
IUUC-Cja-018999	Callithrix jacchus	84.88	0.00e+00	1651.00
IUUC-Cfa-020916	Canis familiaris	87.09	0.00e+00	2201.00
IUUC-Cpo-022146	Cavia porcellus	79.22	0.00e+00	1620.00
IUUC-Csa-024039	Chlorocebus sabaeus	86.18	0.00e+00	2217.00
IUUC-Cho-024914	Choloepus hoffmanni	74.97	0.00e+00	1130.00
IUUC-Cin-025450	Ciona intestinalis	40.69	1.00e-40	160.00
IUUC-Csv-026068	Ciona savignyi	54.96	1.00e-38	152.00
IUUC-Dre-027413	Danio rerio	58.24	0.00e+00	713.00
IUUC-Dno-029438	Dasypus novemcinctus	82.97	0.00e+00	2133.00
IUUC-Dor-030774	Dipodomys ordii	73.52	4.00e-147	516.00
IUUC-Dme-031772	Drosophila melanogaster	29.46	1.00e-34	142.00
IUUC-Ete-033052	Echinops telfairi	80.41	0.00e+00	1505.00
IUUC-Eca-034262	Equus caballus	87.05	0.00e+00	2171.00
IUUC-Eeu-034704	Erinaceus europaeus	70.59	0.00e+00	677.00
IUUC-Fca-036207	Felis catus	83.28	0.00e+00	1202.00
IUUC-Fal-036702	Ficedula albicollis	72.51	0.00e+00	1588.00
IUUC-Gmo-039218	Gadus morhua	51.22	5.00e-91	330.00
IUUC-Gga-040776	Gallus gallus	75.34	0.00e+00	1358.00
IUUC-Gac-042358	Gasterosteus aculeatus	53.55	0.00e+00	671.00
IUUC-Hsa-046560	Homo sapiens	86.95	0.00e+00	2264.00
IUUC-Itr-048135	Ictidomys tridecemlineatus	88.90	0.00e+00	1231.00
IUUC-Laf-054049	Loxodonta africana	85.84	0.00e+00	1711.00
IUUC-Mga-059382	Meleagris gallopavo	74.61	0.00e+00	1831.00
IUUC-Mmr-061301	Microcebus murinus	87.16	0.00e+00	1242.00
IUUC-Mdo-062889	Monodelphis domestica	77.08	0.00e+00	1918.00
IUUC-Mmu-064057	Mus musculus	94.03	0.00e+00	2363.00
IUUC-Mpu-066668	Mustela putorius furo	87.52	0.00e+00	2247.00
IUUC-Mlu-068089	Myotis lucifugus	85.97	0.00e+00	2171.00
IUUC-Nle-069936	Nomascus leucogenys	86.58	0.00e+00	2222.00
IUUC-Oan-073582	Ornithorhynchus anatinus	77.41	0.00e+00	1441.00
IUUC-Ocu-074115	Oryctolagus cuniculus	82.78	0.00e+00	2295.00
IUUC-Ogu-078790	Oryza glumaepatula	50.98	2.00e-13	70.10
IUUC-Ome-081195	Oryza meridionalis	50.98	2.00e-13	69.70
IUUC-Oru-084688	Oryza rufipogon	42.86	2.00e-13	70.10
IUUC-Ola-086709	Oryzias latipes	49.67	0.00e+00	842.00
IUUC-Oga-088100	Otolemur garnettii	84.30	0.00e+00	1193.00
IUUC-Oar-089208	Ovis aries	86.44	0.00e+00	2156.00
IUUC-Ptr-090630	Pan troglodytes	88.49	0.00e+00	1769.00
IUUC-Pan-092146	Papio anubis	82.71	0.00e+00	1508.00
IUUC-Psi-092932	Pelodiscus sinensis	75.55	0.00e+00	1839.00
IUUC-Pfo-096572	Poecilia formosa	53.75	0.00e+00	724.00
IUUC-Pva-102893	Pteropus vampyrus	86.46	0.00e+00	2185.00
IUUC-Sha-106513	Sarcophilus harrisii	77.63	0.00e+00	1466.00
IUUC-Sly-111896	Solanum lycopersicum	33.66	3.00e-08	55.50
IUUC-Sar-113192	Sorex araneus	63.80	5.00e-131	462.00
IUUC-Ssc-116407	Sus scrofa	86.61	0.00e+00	1671.00
IUUC-Tgu-117403	Taeniopygia guttata	73.89	0.00e+00	1823.00
IUUC-Tru-118124	Takifugu rubripes	51.49	5.00e-99	356.00
IUUC-Tsy-119386	Tarsius syrichta	82.49	0.00e+00	1191.00
IUUC-Vpa-130046	Vicugna pacos	84.76	0.00e+00	1984.00
IUUC-Xtr-132132	Xenopus tropicalis	59.65	0.00e+00	1372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence