iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-087105

Ensembl Protein ID

ENSORLP00000006130.1

UniProt Accession

H2LJE2; H2LJE2_ORYLA

Genbank Protein ID

ENSORLP00000006130

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

BAAF04034567

Gene Name

csk; LOC101158271

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000004867.1	ENSORLT00000006131.1	ENSORLP00000006130.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.80e-11	42.5	13	67

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            + + y+++++++ +L ++kGd++++i   ++d +W k+ k+++g++G +P+n+v+k
   Q: 13   ECVARYSFKGTSEQDLPFNKGDILTII-VVTKDPNWYKA-KNAAGQEGTIPANYVQK 67
           68899**********************.9**********.7**************87 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MTEDQNPWPQ GTECVARYSF KGTSEQDLPF NKGDILTIIV VTKDPNWYKA KNAAGQEGTI 60
PANYVQKREG VKTDGKLSLM PWFHGKITRD QAERLLNPPE TGLFLVREST NFPGDYTLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCTGACG GGAAGAGAAG AGCAGCGCGC CCCTCTTGGT AAAAACTCAC TTTTCTTATT 60
GTCCGGGTCA AATTTGGCGG TTCTTTTCTT TCGTGGGGGT TAAAAAAATA GCTATTCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bdi-014440	Brachypodium distachyon	32.26	3.00e-20	94.00
IUUC-Cin-025513	Ciona intestinalis	53.93	8.00e-145	506.00
IUUC-Csv-025899	Ciona savignyi	50.53	7.00e-135	473.00
IUUC-Gga-040506	Gallus gallus	82.96	0.00e+00	790.00
IUUC-Mga-060040	Meleagris gallopavo	81.67	0.00e+00	771.00
IUUC-Ont-072457	Oreochromis niloticus	94.83	0.00e+00	894.00
IUUC-Pfo-096126	Poecilia formosa	94.39	0.00e+00	887.00
IUUC-Tru-118712	Takifugu rubripes	91.76	0.00e+00	857.00
IUUC-Tni-119856	Tetraodon nigroviridis	90.56	0.00e+00	853.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence