iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020545

Ensembl Protein ID

ENSCAFP00000001333.3

UniProt Accession

F1PUE2; F1PUE2_CANLF

Genbank Protein ID

ENSCAFP00000001333

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03007272

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000000936.3	ENSCAFT00000001447.3	ENSCAFP00000001333.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.10e-17	61.1	430	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 430  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDNGQVGLYPANYVEAIQ 486
           799************************.9**********.59*************9885 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSVAYDDSIG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT 60
EWARRWRQLV EKGPQYGTLE KAWTALMSEA ERVSELHLEV KASLMNEDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTACCACT GAACCTGCAT GTGTCTTCCC ATGCATCTCC CACTGTGGAG CTGCTTTGTC 60
TTACTGTGTG GAGTCACAAA GAGAAGTTGA GTTTTACATG TAGGGACAGT GTAAGATCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome
GO:0030100--P:regulation of endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	98.35	0.00e+00	914.00
IUUC-Apl-003574	Anas platyrhynchos	88.30	0.00e+00	791.00
IUUC-Aca-004251	Anolis carolinensis	82.89	0.00e+00	766.00
IUUC-Ame-011756	Astyanax mexicanus	66.93	0.00e+00	685.00
IUUC-Bta-013193	Bos taurus	93.83	0.00e+00	848.00
IUUC-Cel-018168	Caenorhabditis elegans	30.34	2.00e-61	230.00
IUUC-Cja-018756	Callithrix jacchus	95.68	0.00e+00	856.00
IUUC-Cpo-022000	Cavia porcellus	89.92	0.00e+00	914.00
IUUC-Csa-024030	Chlorocebus sabaeus	93.48	0.00e+00	756.00
IUUC-Cin-025707	Ciona intestinalis	43.18	9.00e-108	383.00
IUUC-Csv-026244	Ciona savignyi	41.48	6.00e-54	203.00
IUUC-Dre-028104	Danio rerio	63.82	3.00e-168	584.00
IUUC-Dno-029429	Dasypus novemcinctus	95.81	0.00e+00	826.00
IUUC-Dor-030122	Dipodomys ordii	86.63	0.00e+00	785.00
IUUC-Dme-032120	Drosophila melanogaster	43.06	3.00e-109	388.00
IUUC-Eca-033367	Equus caballus	93.62	0.00e+00	865.00
IUUC-Eeu-034821	Erinaceus europaeus	78.40	0.00e+00	705.00
IUUC-Fca-036079	Felis catus	97.65	0.00e+00	900.00
IUUC-Fal-036682	Ficedula albicollis	88.94	0.00e+00	793.00
IUUC-Gmo-039681	Gadus morhua	65.64	6.00e-159	553.00
IUUC-Gga-040717	Gallus gallus	89.15	0.00e+00	795.00
IUUC-Gac-042262	Gasterosteus aculeatus	64.83	1.00e-175	609.00
IUUC-Ggo-044841	Gorilla gorilla	94.44	0.00e+00	820.00
IUUC-Hsa-046411	Homo sapiens	94.03	0.00e+00	816.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	94.24	0.00e+00	840.00
IUUC-Loc-051975	Lepisosteus oculatus	71.28	0.00e+00	702.00
IUUC-Laf-053839	Loxodonta africana	91.65	0.00e+00	851.00
IUUC-Mcc-055783	Macaca mulatta	93.83	0.00e+00	815.00
IUUC-Mga-060087	Meleagris gallopavo	82.77	0.00e+00	721.00
IUUC-Mmr-060827	Microcebus murinus	95.06	0.00e+00	880.00
IUUC-Mmu-064109	Mus musculus	94.03	0.00e+00	872.00
IUUC-Mpu-066591	Mustela putorius furo	98.56	0.00e+00	915.00
IUUC-Mlu-067826	Myotis lucifugus	96.50	0.00e+00	899.00
IUUC-Nle-069797	Nomascus leucogenys	94.24	0.00e+00	817.00
IUUC-Oan-073076	Ornithorhynchus anatinus	86.38	1.00e-161	561.00
IUUC-Ocu-074425	Oryctolagus cuniculus	94.44	0.00e+00	846.00
IUUC-Oba-075752	Oryza barthii	35.71	5.00e-03	38.10
IUUC-Ola-087556	Oryzias latipes	66.41	4.00e-169	587.00
IUUC-Oga-089009	Otolemur garnettii	86.85	0.00e+00	803.00
IUUC-Oar-089806	Ovis aries	94.24	0.00e+00	851.00
IUUC-Ptr-091111	Pan troglodytes	93.83	0.00e+00	813.00
IUUC-Pan-091749	Papio anubis	91.10	0.00e+00	801.00
IUUC-Psi-093704	Pelodiscus sinensis	88.30	0.00e+00	808.00
IUUC-Pfo-096680	Poecilia formosa	64.52	8.00e-174	603.00
IUUC-Pab-098584	Pongo abelii	93.67	1.00e-158	552.00
IUUC-Pva-102649	Pteropus vampyrus	95.06	0.00e+00	861.00
IUUC-Rno-105431	Rattus norvegicus	93.65	0.00e+00	899.00
IUUC-Sha-106641	Sarcophilus harrisii	90.99	0.00e+00	834.00
IUUC-Sar-113461	Sorex araneus	83.13	0.00e+00	748.00
IUUC-Ssc-115349	Sus scrofa	96.29	0.00e+00	865.00
IUUC-Tgu-116876	Taeniopygia guttata	89.15	0.00e+00	793.00
IUUC-Tru-118306	Takifugu rubripes	68.00	1.00e-179	622.00
IUUC-Tsy-118901	Tarsius syrichta	85.07	2.00e-158	551.00
IUUC-Tni-120120	Tetraodon nigroviridis	69.18	0.00e+00	639.00
IUUC-Xtr-132925	Xenopus tropicalis	82.34	0.00e+00	769.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence