iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049989

Ensembl Protein ID

ENSLACP00000001434.2

UniProt Accession

H2ZVL3; H2ZVL3_LATCH

Genbank Protein ID

ENSLACP00000001434

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01200590

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000001283.2	ENSLACT00000001446.2	ENSLACP00000001434.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-74	251.0	89	417
ULD/UDP/UBQ/UBQ_Other	4.60e-10	39.5	956	1015

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +Gl+Nlg+tCY+N  LQ+ ++  elr++l      k +e+++e+ ++ + ++++++lq lf+ l++s++++++p+e++kal+     ++
   Q: 89   VGLTNLGATCYVNTFLQVWFHNLELRRALYLcqstKAEEEIQED-KDYEPQTICEHLQYLFALLQNSNRRYIDPSEFVKALG-----LD 171
           6***************************9998887777777765.478889******************************9.....78 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           + +qqDaqEf + +l+ le++l                        ++k+   +++i++ F gq+   ++c +c+++s+  ++f++l+l
   Q: 172  TGQQQDAQEFSKLFLSLLEDTL-----------------------CKEKNPDVQNIIQKQFCGQYAYVTVCSHCGRESKLLSKFYELEL 237
           899*******************.......................356788999*********************************** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +++g++     +l+dc  +f kee+legen+y+ce c++k +a++k++l +lP++L l+L+Rf f++++++++k+n+++ fp+ Ld+  
   Q: 238  NIQGHK-----QLTDCVTEFLKEEKLEGENRYFCEACQSKHNATRKIRLLSLPRTLNLQLMRFVFDRQTGHKKKLNTYIGFPEVLDMGA 321
           ******.....9***************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg....................... 327
           ++ ++++    ++ YeL av++H G s+ sGHY+a+v++ + + W++f+D+++++++ ++ +   +                       
   Q: 322  YMDQKDQ----SCVYELNAVLIHRGvSAYSGHYIAHVRDARTGeWYKFNDEEIEKMEGKKLQLGIEediaepsksqtrkpkcgkgthcs 406
           ***9553....79**************************65555************999999866699********************* PP
   S: 328  staYvlfYkrr 338
           ++aY+l+Y+++
   Q: 407  RNAYMLVYRQQ 417
           ********985 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   kvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
            v+   t +eLK +i +++++ p +q+L ++G+ L +d+ tL+++g+ ++s+i+l  +++
   Q: 956  IVSANQTLKELKIQIMHAFSVAPFDQNLAIEGRMLtDDNATLGSLGVVPESVIFLKADEP 1015
           488899*************************************************98875 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWTELVSP EEVRQEHIEM AYRIRLEACK RGVCRRNCKG NPNCLVGMGE 60
HIWLGEIDEN SFHNIDDPNS ERRKKNTFVG LTNLGATCYV NTFLQVWFHN LELRRALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAAGCAC ACTTTCTGAT TTAAAAAAAA AATGTCTGGT TGGACCCCAA TTAGATGGAG 60
CCGATCTAGC TTTTCCTTCT TGATTTATGC TCTGCGTCAC ATTTTTTGAC TGGTTTGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lcm:102354898

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	34.08	3.00e-83	303.00
IUUC-Aml-001357	Ailuropoda melanoleuca	75.38	0.00e+00	1614.00
IUUC-Atr-002976	Amborella trichopoda	32.87	1.00e-82	301.00
IUUC-Apl-003773	Anas platyrhynchos	75.13	0.00e+00	1459.00
IUUC-Aca-004466	Anolis carolinensis	74.95	0.00e+00	808.00
IUUC-Aly-006249	Arabidopsis lyrata	29.75	4.00e-70	259.00
IUUC-Ath-006700	Arabidopsis thaliana	31.62	4.00e-82	299.00
IUUC-Ame-011554	Astyanax mexicanus	69.74	0.00e+00	1493.00
IUUC-Bta-012573	Bos taurus	75.38	0.00e+00	1620.00
IUUC-Bdi-014149	Brachypodium distachyon	33.39	4.00e-84	306.00
IUUC-Bol-016289	Brassica oleracea	26.78	8.00e-82	298.00
IUUC-Bra-017205	Brassica rapa	26.74	4.00e-75	276.00
IUUC-Cja-019991	Callithrix jacchus	75.49	0.00e+00	1613.00
IUUC-Cfa-020294	Canis familiaris	76.41	0.00e+00	1645.00
IUUC-Cpo-021706	Cavia porcellus	73.68	0.00e+00	1532.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	33.33	4.00e-42	168.00
IUUC-Csa-023931	Chlorocebus sabaeus	76.12	0.00e+00	1632.00
IUUC-Cho-024566	Choloepus hoffmanni	72.86	2.00e-114	407.00
IUUC-Cin-025307	Ciona intestinalis	48.47	4.00e-79	287.00
IUUC-Csv-026006	Ciona savignyi	35.07	8.00e-153	534.00
IUUC-Cne-027065	Cryptococcus neoformans	27.93	3.00e-71	263.00
IUUC-Dre-027624	Danio rerio	71.17	0.00e+00	1531.00
IUUC-Dno-029633	Dasypus novemcinctus	75.22	0.00e+00	1066.00
IUUC-Dor-030809	Dipodomys ordii	60.57	0.00e+00	962.00
IUUC-Ete-032818	Echinops telfairi	77.51	0.00e+00	809.00
IUUC-Eca-033692	Equus caballus	76.79	0.00e+00	1633.00
IUUC-Eeu-035185	Erinaceus europaeus	55.36	2.00e-167	583.00
IUUC-Fca-035676	Felis catus	76.20	0.00e+00	1641.00
IUUC-Fal-036913	Ficedula albicollis	76.13	0.00e+00	1620.00
IUUC-Gmo-038532	Gadus morhua	66.79	0.00e+00	1443.00
IUUC-Gga-041041	Gallus gallus	76.77	0.00e+00	1624.00
IUUC-Gac-042570	Gasterosteus aculeatus	67.62	0.00e+00	1478.00
IUUC-Gma-044136	Glycine max	29.15	6.00e-91	329.00
IUUC-Ggo-045367	Gorilla gorilla	72.40	0.00e+00	1518.00
IUUC-Hsa-046019	Homo sapiens	75.93	0.00e+00	1629.00
IUUC-Hvu-047303	Hordeum vulgare	34.66	1.00e-65	243.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	75.14	0.00e+00	1621.00
IUUC-Lpe-051612	Leersia perrieri	33.39	3.00e-81	296.00
IUUC-Loc-052756	Lepisosteus oculatus	73.33	0.00e+00	1607.00
IUUC-Laf-054043	Loxodonta africana	74.18	0.00e+00	1615.00
IUUC-Mcc-054986	Macaca mulatta	74.95	0.00e+00	1614.00
IUUC-Meu-056228	Macropus eugenii	62.46	0.00e+00	698.00
IUUC-Mtr-058610	Medicago truncatula	29.62	5.00e-80	292.00
IUUC-Mga-059896	Meleagris gallopavo	75.15	0.00e+00	1518.00
IUUC-Mvi-060269	Microbotryum violaceum	37.28	5.00e-63	236.00
IUUC-Mmr-060887	Microcebus murinus	75.26	0.00e+00	1622.00
IUUC-Mdo-062506	Monodelphis domestica	76.98	0.00e+00	1652.00
IUUC-Mmu-063642	Mus musculus	73.99	0.00e+00	1599.00
IUUC-Mac-064896	Musa acuminata	32.10	5.00e-81	296.00
IUUC-Mpu-066194	Mustela putorius furo	75.84	0.00e+00	1628.00
IUUC-Mlu-067233	Myotis lucifugus	74.81	0.00e+00	1613.00
IUUC-Nle-069052	Nomascus leucogenys	75.17	0.00e+00	1617.00
IUUC-Opr-070890	Ochotona princeps	78.41	0.00e+00	1024.00
IUUC-Ont-071450	Oreochromis niloticus	65.28	0.00e+00	1422.00
IUUC-Oan-073252	Ornithorhynchus anatinus	69.65	0.00e+00	842.00
IUUC-Ocu-073796	Oryctolagus cuniculus	75.63	0.00e+00	1406.00
IUUC-Oba-075563	Oryza barthii	26.09	1.00e-83	304.00
IUUC-Obr-076394	Oryza brachyantha	33.49	3.00e-83	303.00
IUUC-Ogl-077339	Oryza glaberrima	37.50	2.00e-40	159.00
IUUC-Ogu-079007	Oryza glumaepatula	25.78	4.00e-77	283.00
IUUC-Oin-079997	Oryza indica	26.09	8.00e-84	305.00
IUUC-Olo-080364	Oryza longistaminata	25.77	2.00e-84	307.00
IUUC-Ome-081165	Oryza meridionalis	26.01	3.00e-78	286.00
IUUC-Oni-083026	Oryza nivara	26.09	1.00e-83	305.00
IUUC-Opu-083284	Oryza punctata	26.06	3.00e-78	286.00
IUUC-Oru-084797	Oryza rufipogon	26.09	1.00e-83	305.00
IUUC-Osa-086221	Oryza sativa	37.50	2.00e-40	159.00
IUUC-Ola-086568	Oryzias latipes	67.35	0.00e+00	1466.00
IUUC-Oga-088687	Otolemur garnettii	75.47	0.00e+00	1608.00
IUUC-Oar-090345	Ovis aries	75.30	0.00e+00	1550.00
IUUC-Ptr-090734	Pan troglodytes	76.03	0.00e+00	1631.00
IUUC-Pan-091704	Papio anubis	73.31	0.00e+00	1551.00
IUUC-Psi-092937	Pelodiscus sinensis	74.95	0.00e+00	1395.00
IUUC-Ppa-095808	Physcomitrella patens	29.25	2.00e-74	274.00
IUUC-Pab-098129	Pongo abelii	76.03	0.00e+00	1631.00
IUUC-Pop-099738	Populus trichocarpa	31.72	4.00e-79	290.00
IUUC-Pca-100647	Procavia capensis	84.85	2.00e-169	589.00
IUUC-Ppe-102091	Prunus persica	32.47	3.00e-84	306.00
IUUC-Pva-102719	Pteropus vampyrus	75.26	0.00e+00	1617.00
IUUC-Rno-105363	Rattus norvegicus	75.55	0.00e+00	1626.00
IUUC-Sha-107620	Sarcophilus harrisii	73.90	0.00e+00	1538.00
IUUC-Smo-109487	Selaginella moellendorffii	28.09	6.00e-87	315.00
IUUC-Sit-110683	Setaria italica	32.96	2.00e-82	300.00
IUUC-Sly-111377	Solanum lycopersicum	29.41	6.00e-83	302.00
IUUC-Stu-111969	Solanum tuberosum	30.85	7.00e-70	258.00
IUUC-Sar-113099	Sorex araneus	74.81	0.00e+00	1389.00
IUUC-Sbi-113833	Sorghum bicolor	44.07	3.00e-60	224.00
IUUC-Ssc-115279	Sus scrofa	66.06	0.00e+00	1015.00
IUUC-Tgu-117519	Taeniopygia guttata	73.11	0.00e+00	1462.00
IUUC-Tru-117651	Takifugu rubripes	68.00	0.00e+00	1467.00
IUUC-Tsy-119201	Tarsius syrichta	73.23	0.00e+00	1462.00
IUUC-Tni-120840	Tetraodon nigroviridis	68.81	0.00e+00	1491.00
IUUC-Tca-121674	Theobroma cacao	27.33	5.00e-85	309.00
IUUC-Tae-125814	Triticum aestivum	27.31	4.00e-84	306.00
IUUC-Tur-126599	Triticum urartu	33.81	4.00e-82	300.00
IUUC-Tbe-127782	Tupaia belangeri	68.46	0.00e+00	1393.00
IUUC-Ttr-128312	Tursiops truncatus	74.40	0.00e+00	1600.00
IUUC-Vpa-130348	Vicugna pacos	75.05	0.00e+00	1547.00
IUUC-Vvi-131353	Vitis vinifera	31.37	5.00e-83	302.00
IUUC-Xtr-132172	Xenopus tropicalis	67.62	0.00e+00	1296.00
IUUC-Xma-133263	Xiphophorus maculatus	67.74	0.00e+00	1442.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence