iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007046

UUCD1 version

UUC-ArT-00718

Ensembl Protein ID

AT1G79380.1

UniProt Accession

Q9SAL0; RGLG4_ARATH

Genbank Protein ID

AAD30238.1; AEE36236.1; AAK50068.1; AAM91415.1

Protein Name

E3 ubiquitin-protein ligase RGLG4; RING domain ligase 4

Genbank Nucleotide ID

AC007202; CP002684; AF372928; AY133585

Gene Name

RGLG4; At1g79380; T8K14.20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G79380	AT1G79380.1	AT1G79380.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	64.90	5.00e-141	497.00	IUUC-Oin-079486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis thaliana

Functional Description
(View)

Possesses E3 ubiquitin-protein ligase in vitro. Acts as upstream modulator of jasmonate (JA) signaling in response to various stimuli, such as JA-inhibited root growth, JA-inductive gene expression, coronatine-mediated pathogen susceptibility, wound-stimulated expression of JA-responsive genes and wound-induced JA biosynthesis (PubMed:22898498). Controls fumonisin B1 (FB1)-triggered programmed cell death (PCD) by modulating the JA signaling pathway. May mediate salicylic acid (SA) suppression of JA signaling in FB1-induced responses (PubMed:25788731). May mediate the formation of 'Lys-48'-linked multiubiquitin chains. Mediates the polyubiquitination and subsequent proteasomal degradation of the target protein GRXS17 (PubMed:27497447).

Protein Sequence
(Fasta)

MTMGNFLKRF GSGKSRSSRN MTLGTTSSQS HEPSPSDPSL SLADNTNATK KKYALIPDRF 60
SSLDQVSKAL REAGLESSNL ILGVDFTKSN EWTGKTSFDG KCLHALGETS NPYEKAIFVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATATAGTT TAATTTTTTT CTAGGTTTTC GTTCGAACTC ATGTGGGTTC AGTAAATAAA 60
TGTTTAAGTC CCCATCTGGC CGCGTCAAAA ATACTTAGAT AACAACAATT AGTGGTTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1184--Jasmonic acid signaling pathway
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR010734--Copine
IPR002035--VWF_A
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF07002--Copine

SMART

SM00184--RING
SM00327--VWA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042742--P:defense response to bacterium
GO:0009867--P:jasmonic acid mediated signaling pathway
GO:0009611--P:response to wounding

KEGG

ath:AT1G79380

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000336	Aegilops tauschii	59.17	5.00e-133	466.00
IUUC-Aly-006470	Arabidopsis lyrata	92.57	0.00e+00	721.00
IUUC-Bdi-014120	Brachypodium distachyon	66.19	9.00e-138	482.00
IUUC-Bol-015590	Brassica oleracea	81.72	3.00e-174	603.00
IUUC-Bra-017517	Brassica rapa	86.74	2.00e-179	620.00
IUUC-Cin-025331	Ciona intestinalis	44.75	3.00e-60	223.00
IUUC-Csv-026082	Ciona savignyi	44.03	2.00e-58	218.00
IUUC-Gma-043431	Glycine max	66.48	2.00e-147	514.00
IUUC-Hvu-047280	Hordeum vulgare	65.36	6.00e-138	483.00
IUUC-Lpe-050854	Leersia perrieri	66.47	1.00e-129	455.00
IUUC-Mtr-057746	Medicago truncatula	61.54	2.00e-147	514.00
IUUC-Mac-064929	Musa acuminata	63.76	4.00e-135	473.00
IUUC-Oba-075646	Oryza barthii	65.46	2.00e-142	498.00
IUUC-Obr-076348	Oryza brachyantha	64.15	5.00e-138	483.00
IUUC-Ogl-077724	Oryza glaberrima	65.46	2.00e-142	498.00
IUUC-Ogu-078761	Oryza glumaepatula	66.29	3.00e-144	504.00
IUUC-Oin-079486	Oryza indica	64.90	3.00e-142	497.00
IUUC-Olo-080860	Oryza longistaminata	66.87	3.00e-133	467.00
IUUC-Ome-081961	Oryza meridionalis	64.62	3.00e-138	484.00
IUUC-Oni-082777	Oryza nivara	64.90	3.00e-142	497.00
IUUC-Opu-083462	Oryza punctata	65.74	1.00e-142	498.00
IUUC-Oru-084281	Oryza rufipogon	64.90	3.00e-142	497.00
IUUC-Osa-085996	Oryza sativa	64.90	5.00e-142	496.00
IUUC-Pop-099228	Populus trichocarpa	67.76	3.00e-139	486.00
IUUC-Ppe-101837	Prunus persica	66.67	9.00e-146	508.00
IUUC-Sit-109766	Setaria italica	60.49	2.00e-141	494.00
IUUC-Sly-111313	Solanum lycopersicum	67.99	1.00e-146	512.00
IUUC-Stu-112622	Solanum tuberosum	69.12	7.00e-148	516.00
IUUC-Sbi-114438	Sorghum bicolor	58.35	7.00e-141	493.00
IUUC-Tca-121234	Theobroma cacao	71.51	4.00e-153	533.00
IUUC-Tae-123953	Triticum aestivum	64.15	6.00e-138	483.00
IUUC-Tur-126574	Triticum urartu	67.33	1.00e-138	485.00
IUUC-Vvi-131358	Vitis vinifera	64.44	4.00e-134	470.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence