iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073308

Ensembl Protein ID

ENSOANP00000023386.1

UniProt Accession

F7BXQ2; F7BXQ2_ORNAN

Genbank Protein ID

ENSOANP00000023386

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01287704

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000014851.2	ENSOANT00000023390.2	ENSOANP00000023386.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	28.70	2.00e-08	57.80	IUUC-Dme-031659
UBD/Alpha-Helix/UBA	64.52	8.00e-135	478.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	64.52	8.00e-135	478.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	62.96	3.00e-144	508.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	63.25	2.00e-141	498.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

RSKAYLLGKE ESHREIRRFT RCDRLLRRLD QVFPALRPGT FQAYYRDEDG DMIAFSSDEE 60
LKMALPYVKD NILRIFIKVE KRECKREHRP PCSQEPPQNM VHPNVTCDGC QGPVVGTRFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGTCCAAGG CCTACCTGCT GGGCAAGGAG GAGTCGCACC GCGAGATCCG CCGCTTCACC 60
CTGGGCCCCC CGGAGCCGCC CGGCGGGCCC GGCTGCTGCG ACCGGCTGCT CCGCCGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0042802--F:identical protein binding
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016239--P:positive regulation of macroautophagy
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	60.86	3.00e-121	427.00
IUUC-Apl-003897	Anas platyrhynchos	59.43	5.00e-123	433.00
IUUC-Aca-004699	Anolis carolinensis	47.15	2.00e-97	348.00
IUUC-Ame-010982	Astyanax mexicanus	69.83	7.00e-40	157.00
IUUC-Bgr-012289	Blumeria graminis	35.53	1.00e-09	58.50
IUUC-Bta-012634	Bos taurus	62.81	7.00e-145	506.00
IUUC-Bci-013659	Botrytis cinerea	31.58	3.00e-09	57.00
IUUC-Cel-018660	Caenorhabditis elegans	50.00	9.00e-13	65.90
IUUC-Cja-019684	Callithrix jacchus	62.22	2.00e-144	504.00
IUUC-Cfa-020573	Canis familiaris	55.77	4.00e-89	320.00
IUUC-Cpo-021425	Cavia porcellus	57.76	2.00e-120	425.00
IUUC-Csa-023968	Chlorocebus sabaeus	62.22	5.00e-143	500.00
IUUC-Cho-024596	Choloepus hoffmanni	63.69	1.00e-32	132.00
IUUC-Cin-025557	Ciona intestinalis	30.59	4.00e-19	87.80
IUUC-Csv-025974	Ciona savignyi	26.17	6.00e-14	70.90
IUUC-Cne-027045	Cryptococcus neoformans	48.39	2.00e-10	60.80
IUUC-Cme-027152	Cyanidioschyzon merolae	51.52	6.00e-05	42.00
IUUC-Dre-028621	Danio rerio	43.40	1.00e-55	210.00
IUUC-Dno-029060	Dasypus novemcinctus	61.86	2.00e-143	501.00
IUUC-Dor-030547	Dipodomys ordii	59.33	3.00e-84	304.00
IUUC-Dme-031659	Drosophila melanogaster	27.46	4.00e-10	59.30
IUUC-Ete-033201	Echinops telfairi	58.87	4.00e-111	393.00
IUUC-Eca-033456	Equus caballus	66.84	4.00e-135	473.00
IUUC-Eeu-035157	Erinaceus europaeus	64.18	7.00e-121	426.00
IUUC-Fca-035403	Felis catus	59.40	3.00e-137	481.00
IUUC-Fal-036798	Ficedula albicollis	61.06	3.00e-139	487.00
IUUC-Fso-038342	Fusarium solani	31.58	4.00e-09	56.20
IUUC-Gmo-039619	Gadus morhua	47.04	2.00e-50	191.00
IUUC-Ggr-039979	Gaeumannomyces graminis	29.63	1.00e-08	55.10
IUUC-Gga-040137	Gallus gallus	60.40	3.00e-137	481.00
IUUC-Gac-042410	Gasterosteus aculeatus	75.00	7.00e-36	144.00
IUUC-Ggo-044690	Gorilla gorilla	62.44	3.00e-144	504.00
IUUC-Hsa-046390	Homo sapiens	62.44	6.00e-144	503.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	63.05	2.00e-145	508.00
IUUC-Lch-049658	Latimeria chalumnae	49.23	2.00e-110	391.00
IUUC-Loc-052589	Lepisosteus oculatus	47.60	9.00e-106	376.00
IUUC-Laf-053746	Loxodonta africana	56.67	5.00e-128	450.00
IUUC-Mcc-055635	Macaca mulatta	63.11	3.00e-143	500.00
IUUC-Meu-056528	Macropus eugenii	56.09	5.00e-69	253.00
IUUC-Mpo-057400	Magnaporthe poae	29.63	1.00e-08	54.70
IUUC-Mla-059147	Melampsora laricipopulina	52.50	8.00e-08	50.80
IUUC-Mga-059458	Meleagris gallopavo	62.94	4.00e-127	447.00
IUUC-Mmr-061539	Microcebus murinus	58.11	3.00e-79	288.00
IUUC-Mdo-063083	Monodelphis domestica	66.29	3.00e-158	550.00
IUUC-Mmu-063589	Mus musculus	63.83	1.00e-154	538.00
IUUC-Mpu-065727	Mustela putorius furo	61.81	2.00e-125	441.00
IUUC-Mlu-067026	Myotis lucifugus	63.94	5.00e-128	449.00
IUUC-Nle-069356	Nomascus leucogenys	49.13	4.00e-82	297.00
IUUC-Opr-071091	Ochotona princeps	53.46	5.00e-55	207.00
IUUC-Ont-071864	Oreochromis niloticus	47.51	7.00e-98	350.00
IUUC-Ocu-074110	Oryctolagus cuniculus	63.36	3.00e-146	511.00
IUUC-Ola-086944	Oryzias latipes	45.69	2.00e-37	147.00
IUUC-Oga-088869	Otolemur garnettii	62.01	5.00e-143	500.00
IUUC-Oar-089857	Ovis aries	64.96	4.00e-129	454.00
IUUC-Ptr-091640	Pan troglodytes	62.44	4.00e-144	503.00
IUUC-Pan-092831	Papio anubis	62.94	8.00e-142	496.00
IUUC-Psi-093925	Pelodiscus sinensis	59.14	7.00e-133	466.00
IUUC-Pma-094576	Petromyzon marinus	31.06	1.00e-26	113.00
IUUC-Pfo-097297	Poecilia formosa	46.04	7.00e-86	310.00
IUUC-Pab-098725	Pongo abelii	57.52	2.00e-126	444.00
IUUC-Pca-101106	Procavia capensis	60.93	1.00e-141	495.00
IUUC-Pva-102710	Pteropus vampyrus	58.02	2.00e-118	418.00
IUUC-Pgr-103390	Puccinia graminis	40.96	9.00e-10	59.70
IUUC-Rno-105539	Rattus norvegicus	64.59	2.00e-152	531.00
IUUC-Sha-107469	Sarcophilus harrisii	61.27	7.00e-127	446.00
IUUC-Spo-108198	Schizosaccharomyces pombe	37.04	6.00e-07	47.80
IUUC-Ssl-108622	Sclerotinia sclerotiorum	32.89	1.00e-09	58.20
IUUC-Ssc-115526	Sus scrofa	60.57	3.00e-145	507.00
IUUC-Tgu-117194	Taeniopygia guttata	63.85	5.00e-127	446.00
IUUC-Tru-117896	Takifugu rubripes	46.83	1.00e-95	342.00
IUUC-Tni-119943	Tetraodon nigroviridis	44.54	1.00e-85	309.00
IUUC-Ttr-128676	Tursiops truncatus	61.64	3.00e-145	507.00
IUUC-Vda-129812	Verticillium dahliae	37.33	3.00e-07	50.10
IUUC-Vpa-130319	Vicugna pacos	73.00	2.00e-44	172.00
IUUC-Xtr-132907	Xenopus tropicalis	55.08	2.00e-134	471.00
IUUC-Xma-133047	Xiphophorus maculatus	47.97	1.00e-89	322.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence